An interventional study of Mindfulness-based Intervention for Tics and Tic Information and Coping Strategies in Tourette Syndrome and Persistent Tic Disorder, sponsored by Bowdoin College. Completed at 2 sites in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-04-29.
Sponsored by Bowdoin College · Not applicable, Interventional, and Treatment
Tourette Syndrome (TS) and Persistent Tic Disorder (PTD) are chronic and potentially disabling neurobiological conditions. Although a range of pharmacological and psychosocial treatments exists, a significant number of individuals either do not respond to the current treatments or find them unacceptable. Thus, it is essential that researchers continue to develop and test novel treatment approaches.
In this randomized controlled trial the investigators will compare two different online group-based interventions for tics: a mindfulness-based program (Mindfulness-based Intervention for Tics (MBIT), and a psychoeducational and supportive therapy program (Tic Information and Coping Strategies (TICS)). The purpose of this study is to determine which intervention is more helpful for adults with a tic disorder.
240 studies on the registry are indexed under Tourette Syndrome; 40 are open to participants now.
This study's enrollment of 37 is close to the median of 36 across 183 interventional studies indexed under Tourette Syndrome.
Browse Tourette Syndrome studies →Bowdoin College is the lead sponsor of 3 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
8-week group-based mindfulness-based program
Behavioral: Mindfulness-based Intervention for Tics
8-week group-based educational and supportive therapy program
Behavioral: Tic Information and Coping Strategies
Psychological intervention that focuses on cultivating awareness of urges to tic and developing a different relationship to those urges through meditation and other mindfulness practices.
Psychological Intervention that focuses on learning more about tics, practicing a range of strategies for coping with tics (e.g., relaxation, effective communication), and discussing challenges commonly experienced by individuals with tics.
Change in Yale Global Tic Severity Scale (YGTSS) Total Tic Severity Score
Clinician-rated measure of tic severity
Time frame: Screening, Week 0, Week 9, Week 13, Week 35
Clinical Global Impressions Scale
Time frame: Weeks 0, 9, 13, 35
Adult Tic Questionnaire
Time frame: Weeks 0, 9, 13, 35
Yale-Brown Obsessive Compulsive Scale
Time frame: Weeks 0, 9, 13, 35
Attention-Deficit Hyperactivity Rating Scale
Time frame: Weeks 0, 9, 13, 35
Depression Anxiety Stress Scale
Time frame: Weeks 0, 9, 13, 35
Premonitory Urge to Tic Scale
Time frame: Weeks 0, 9, 13, 35
Tic Rating Form
Time frame: Weeks 1-8
Problem Rating Form
Time frame: Weeks 1-8
Patient Health Questionnaire-9
Time frame: Weeks 0, 9, 13, 35
Work and Social Adjustment Survey
Time frame: Weeks 0, 9, 13, 35
Five Facet Mindfulness Questionnaire
Time frame: Weeks 0, 4, 8, 9, 13, 35
Credibility and Expectancy Questionnaire
Time frame: Week 3
Patient Satisfaction Questionnaire
Time frame: Week 9
Self Compassion Scale
Time frame: Weeks 0, 9, 13, 35
Affective Reactivity Index
Time frame: Weeks 0, 9, 13, 35
Brief Irritability Test
Time frame: Weeks 0, 9, 13, 35
Plan to share: No
Ran from Nov 2018 to primary completion in Dec 2020, 24 months.
Of 65 non-industry interventional studies with no phase under Tourette Syndrome, half reached primary completion within 33 months of starting (the median), counting those still running; a quarter within 22 and three quarters within 50. This study's 24 months is below that.
Counting every sponsor, half of 65 studies reached it within 33 months; a quarter within 22 and three quarters within 50.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Apr 2024. You cannot join it, but the record below documents what was studied.
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Bowdoin College