Tourette Syndrome clinical trials
The registry lists 240 studies for Tourette Syndrome across more than 10 countries. 40 are recruiting or about to start. 200 of them are mainly about Tourette Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
National Institute of Neurological Disorders and Stroke (NINDS) (12) · Yale University (9) · Johns Hopkins University (9) · University of Florida (8) · Neurocrine Biosciences (8) · University of Utah (6) · Emalex Biosciences Inc. (6) · Vanderbilt University Medical Center (6)
What is being tested here
Drugs under test in Tourette Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Sertraline | 1 | 0 | 1 |
| Ornidazole | 1 | 0 | 1 |
| Medical Marijuana | 1 | 0 | 1 |
| Aripiprazole | 0 | 7 | 10 |
| Valbenazine | 0 | 0 | 8 |
| Ecopipam | 0 | 2 | 6 |
| Lactiplantibacillus plantarum PS128 | 0 | 0 | 2 |
| Deutetrabenazine | 0 | 1 | 2 |
| Guanfacine | 0 | 1 | 2 |
| ABX-1431 | 0 | 0 | 2 |
Drug classes tested here Antipsychotics 19
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Dec 2026Neurofeedback From the Supplementary Motor Area for Tourette Syndrome · Yale University
- Jan 2027Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals · Massachusetts General Hospital
- Feb 2027Multimodal Electrophysiological Study of Cortico-subcortical Biomarkers of Tics in Tourette Syndrome · University Hospital, Bordeaux
- Feb 2027Neural Correlates of Sensory Phenomena in Tourette Syndrome · Vanderbilt University Medical Center
- Mar 2027Longitudinal Impact of Stressors in Adults With Tourette Syndrome · Vanderbilt University Medical Center
- Aug 2027Integrating Exposure and Response Prevention and Habit Reversal Techniques to Treat a Tourettic Subtype of Obsessive-Compulsive Disorder (Tourettic OCD) · University College London Hospitals
- Sep 2027Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders · Holland Bloorview Kids Rehabilitation Hospital
- Sep 2027Serotonin Control of Impulsivity in Tourette Disorder · Hospices Civils de Lyon
- Sep 2027Characterising Sleep Disorders in Children With Tourette Syndrome · Steffi Baker
- Oct 2027SCI-110 in the Treatment of Tourette Syndrome · Neurothera Labs Inc.
Who these studies take
Of the 33 Tourette Syndrome studies recruiting now, 9 (27%) set no upper age limit and 22 (67%) stop at 75 or younger. 20 (61%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 9 (27%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 13 (39%) | 13 (39%) |
| 18 | 23 (70%) | 23 (70%) |
| 30 | 18 (55%) | 18 (55%) |
| 40 | 18 (55%) | 18 (55%) |
| 50 | 18 (55%) | 18 (55%) |
| 65 | 15 (45%) | 15 (45%) |
| 75 | 11 (33%) | 11 (33%) |
| 85 | 11 (33%) | 11 (33%) |
Across all 240 studies, recruiting or not: 77% stop at 75 or younger and 75% at 65; 65% take children; 0% are for women only and 1% for men only; 18% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Tourette Syndrome studies take
Of 19 phase 2 interventional studies under Tourette Syndrome, half reached primary completion within 25 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 25 mo15–42 · 19 studies | — | — |
| Interventional, no phase | 33 mo22–50 · 65 studies | — | 33 mo22–50 · 65 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Newly registered1
- Evaluating and Promoting Resilience in Adolescents With Tourette SyndromeOct 30, 2026NCT07905898
Studies
Recruiting first, then most recently updated. Showing 50 of 240. Browse all 240 → or search them.
- Deep Brain Stimulation Therapy in Movement DisordersRecruitingNCT02119611Not applicable1 country
- Evaluating and Promoting Resilience in Adolescents With Tourette SyndromeNot yet recruitingNCT07905898Not applicable1 country
- Transcutaneous Auricular Vagus Nerve Stimulation for Chronic Tic Disorders/Tourette's Syndrome in Children and AdolescentsNot yet recruitingNCT07854665Not applicable1 country
- Exploring the Role of Neuroactive Steroids in Tourette SyndromeRecruitingNCT05281445Not applicable1 country
- Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental DisordersRecruitingNCT06081348Phase 21 country
- Integrating Exposure and Response Prevention and Habit Reversal Techniques to Treat a Tourettic Subtype of Obsessive-Compulsive Disorder (Tourettic OCD)RecruitingNCT07725926Not applicable1 country
- Multimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for TicsRecruitingNCT06194305Phase 21 country
- Trajectories of Change in Tourette SyndromeRecruitingNCT06679790Not applicable1 country
- Transcranial Ultrasound Stimulation for Tourette SyndromeNot yet recruitingNCT07699783Phase 1
- Neurofeedback From the Supplementary Motor Area for Tourette SyndromeRecruitingNCT05558566Not applicable1 country
- CBIT+TMS R33 PhaseRecruitingNCT06678737Phase 21 country
- Remote Delivery of a Mindfulness-based Intervention for TicsRecruitingNCT06408662Not applicable1 country
- Longitudinal Impact of Stressors in Adults With Tourette SyndromeRecruitingNCT048516781 country
- SCI-110 in the Treatment of Tourette SyndromeNot yet recruitingNCT05126888Phase 23 countries
- A Multicenter Pediatric Deep Brain Stimulation RegistryRecruitingNCT065856181 country
- Sensory Symptoms in Tourette SyndromeRecruitingNCT038514841 country
- Observational Database on Deep Brain Stimulation in Tourette SyndromeRecruitingNCT044490681 country
- Characterising Sleep Disorders in Children With Tourette SyndromeNot yet recruitingNCT07450079
- Epidemiology of Assertiveness and Emotion Management Disorders in People With Tourette's SyndromeRecruitingNCT06136572Not applicable1 country
- Objective Characterizatoion of Repetitive BehaviorsRecruitingNCT06050369Not applicable1 country
- Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation ResearchRecruitingNCT048066201 country
- Neural Correlates of Sensory Phenomena in Tourette SyndromeEnrolling by invitationNCT039146641 country
- Sensorimotor and Psychosocial Trajectories in Adolescents With Tic DisorderRecruitingNCT065767261 country
- Where Wild Things Grow: Nature- and Activity-based Group Interventions for Neurodivergent Children and YouthRecruitingNCT07203469Not applicable1 country
- Strengthening Tourette Treatment OPtions Using TMS to Improve CBIT, a Double-blind, Randomized, Controlled StudyRecruitingNCT05705999Not applicable1 country
- Cognitive-psychophysiological Treatment for Tics in Young People With Tourette's Syndrome With or Without BiofeedbackRecruitingNCT06873841Not applicable1 country
- Investigating Changes in Premonitory Urges During Habit Reversal Training for TicsRecruitingNCT06825520Not applicable1 country
- Multitarget Stereotactic Electrophysiological Recording and Stimulation for Tourette SyndromeRecruitingNCT06889480Not applicable1 country
- Multimodal Electrophysiological Study of Cortico-subcortical Biomarkers of Tics in Tourette SyndromeRecruitingNCT06909656Not applicable1 country
- Forehead Temperature-Regulating Therapy for Insomnia in Adults With Tourette's DisorderRecruitingNCT05499741Not applicable1 country
- Effect of RNS in Treatment-refractory Tourette's SyndromeRecruitingNCT06785532Not applicable1 country
- Serotonin Control of Impulsivity in Tourette DisorderRecruitingNCT05942716Phase 21 country
- Effectiveness of Symptom Management Application on Parental Care Ability of Children With Tourette SyndromeRecruitingNCT06613126Not applicable1 country
- Washed Microbiota Transplantation for Tourette's SyndromeRecruitingNCT03764748Phase 11 country
- The Findings of Magnetic Resonance Imaging in Subtypes of Tics-related DisordersRecruitingNCT055664961 country
- Clinical Characteristics and Temporal Properties of Individual Tics in Persistent Tic DisorderRecruitingNCT06385535Not applicable1 country
- Peripheral Mechanisms of Humoral Immune Effector-mediated Tourette's Syndrome and the Role of Tuina InterventionRecruitingNCT06379373Not applicable1 country
- Exploring DBS Efficacy in Treatment-refractory Tourette's SyndromeNot yet recruitingNCT06361004Not applicable1 country
- Internet-based Behavior Therapy for Adults With Tourette SyndromeRecruitingNCT06271083Not applicable1 country
- Outcomes Mandate National Integration With Cannabis as MedicineRecruitingNCT03944447Phase 21 country
- Physiological Investigations of Movement DisordersCompletedNCT01019343Not applicable1 country
- Expanded Access Program for Treatment With Ecopipam for Tourette's DisorderNo longer availableNCT070935411 country
- Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cells for Tourette SyndromeWithdrawnNCT05158439Phase 1
- Repetitive Transcranial Magnetic Stimulation of the Posterior Parietal Cortex in Patients Suffering From Gilles de la Tourette SyndromeTerminatedNCT01043549Not applicable1 country
- Evaluation of an Online Comprehensive Behavioral Intervention for Tics (CBIT) Therapist Training ProgramCompletedNCT05547854Not applicable1 country
- Study on the Mechanism of Pei Tu Ning Feng Tang in Alleviating Tourette Syndrome Via Functional Near-Infrared Spectroscopy (fNIRS) and the DA-MAPK-BDNF PathwayCompletedNCT07417371Not applicable1 country
- Tourette Deep Brain Stimulation (DBS) Target Detection & SuppressionActive, not recruitingNCT05371041Not applicable1 country
- Cognitive and Brain Development in Adolescents With Gilles de la Tourette SyndromeCompletedNCT04179435Not applicable1 country
- Epidiolex in Obsessive Compulsive Disorder and Related DisordersCompletedNCT04978428Phase 21 country
- A Study to Evaluate Long-term Safety of Ecopipam Tablets in Children, Adolescents and Adults With Tourette's DisorderActive, not recruitingNCT06021522Phase 38 countries