Movement Disorders clinical trials
The registry lists 371 studies for Movement Disorders across more than 10 countries. 102 are recruiting or about to start. 83 of them are mainly about Movement Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 30 narrower conditions too, such as Parkinson Disease: 6,947 studies, 1,616 open.
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A study of drug A after surgery for early breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Status
Who runs them
National Institute of Neurological Disorders and Stroke (NINDS) (40) · Drexel University College of Medicine (10) · Boston Children's Hospital (5) · Radboud University Medical Center (5) · Oregon Health and Science University (5) · Chinese PLA General Hospital (4) · University College, London (4) · Praxis Precision Medicines (4)
What is being tested here
Drugs under test in Movement Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Psilocybin | 2 | 0 | 3 |
| Deutetrabenazine | 1 | 3 | 4 |
| Z944 | 1 | 1 | 3 |
| ONO-2808 | 1 | 1 | 1 |
| Ambroxol | 1 | 1 | 1 |
| Tavapadon | 0 | 4 | 6 |
| Suvecaltamide | 0 | 0 | 3 |
| Preladenant | 0 | 0 | 3 |
| Mavoglurant | 0 | 0 | 3 |
| T-2000 | 0 | 0 | 3 |
Drug classes tested here Serotonin receptor agonists 2 open · Calcium channel blockers 1 open · Dopamine agonists 7 · Antipsychotics 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Dec 2026Monitoring Daily Mobility in Children With Autism · IRCCS San Raffaele Roma
- Dec 2026Effects of Targeted Temporal Interference Stimulation of Cerebellar Nuclei on Tremor and Gait Disturbance in Parkinson's Disease Patients · YangPan
- Dec 2026Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control · Jorge Gonzalez-Martinez
- Dec 2026Open Label Study for the Use of Low Intensity Focused Ultrasound for Essential Tremor · University of California, Los Angeles
- Feb 2027Analysis of Cutaneous Phosphorylated Alpha-Synuclein to Identify Patients at Risk of Progressing From Essential Tremor to Parkinson's Disease · CND Life Sciences
- Mar 2027Safety and Pharmacodynamic Effects of BIIB122 in Participants With LRRK2-Associated Parkinson's Disease (LRRK2-PD) · Denali Therapeutics Inc.
- Mar 2027Effects of Stimulation Patterns of Deep Brain Stimulation · Duke University
- Mar 2027Cognitive Decline Following Deep Brain Stimulation · Medical University of South Carolina
- Apr 2027Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq) · Boston Children's Hospital
- Apr 2027Leg Stretching Using an Exoskeleton on Demand for People With Spasticity · VA Office of Research and Development
Who these studies take
Of the 74 Movement Disorders studies recruiting now, 29 (39%) set no upper age limit and 18 (24%) stop at 75 or younger. 16 (22%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 17 (23%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 15 (20%) | 15 (20%) |
| 18 | 55 (74%) | 55 (74%) |
| 30 | 58 (78%) | 58 (78%) |
| 40 | 65 (88%) | 65 (88%) |
| 50 | 67 (91%) | 67 (91%) |
| 65 | 65 (88%) | 65 (88%) |
| 75 | 62 (84%) | 62 (84%) |
| 85 | 48 (65%) | 48 (65%) |
Across all 371 studies, recruiting or not: 27% stop at 75 or younger and 15% at 65; 23% take children; 1% are for women only and 1% for men only; 23% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Movement Disorders studies take
Of 22 phase 2 interventional studies under Movement Disorders, half reached primary completion within 24 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 24 mo17–40 · 22 studies | — | — |
| Interventional, no phase | 33 mo11–80 · 85 studies | — | 33 mo11–80 · 83 studies |
| Observational | 59 mo33–95 · 60 studies | — | 59 mo35–72 · 49 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 371. Browse all 371 → or search them.
- Analysis of Cutaneous Phosphorylated Alpha-Synuclein to Identify Patients at Risk of Progressing From Essential Tremor to Parkinson's DiseaseRecruitingNCT074284471 country
- A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic TherapyRecruitingNCT07804615Phase 22 countries
- Deep Brain Stimulation Surgery for Movement DisordersRecruitingNCT01581580Not applicable1 country
- Botulinum Toxin for the Treatment of Involuntary Movement DisordersRecruitingNCT000012081 country
- A Study of SGT-212 Gene Therapy in Friedreich's AtaxiaRecruitingNCT07180355Phase 11 country
- Genetic Characterization of Movement Disorders and DementiasRecruitingNCT020142461 country
- Human Movement DatabaseRecruitingNCT000012521 country
- Evaluating the Effects of the EXOPULSE Suit on Mobility, Walking Ability, and Balance in People With Multiple SclerosisNot yet recruitingNCT07897760Not applicable2 countries
- Phenotype/Genotype Correlations in Movement DisordersRecruitingNCT000188891 country
- Monitoring Daily Mobility in Children With AutismRecruitingNCT07519369Not applicable1 country
- Deep Brain Stimulation Therapy in Movement DisordersRecruitingNCT02119611Not applicable1 country
- Video-oculography and Parkinson's DiseaseRecruitingNCT04731246Not applicable1 country
- Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System - RAPID for CNSRecruitingNCT065536252 countries
- Essential 3 - Decentralized, Phase 3 Study Evaluating the Safety and Efficacy of Ulixacaltamide in Essential Tremor (ET)RecruitingNCT06087276Phase 31 country
- Leg Stretching Using an Exoskeleton on Demand for People With SpasticityRecruitingNCT05926596Not applicable1 country
- A Manualized Recreational Therapy Balance Program for Older Adults With Parkinson's and Movement DisordersNot yet recruitingNCT07845474Not applicable1 country
- The Efficacy of Psilocybin Therapy for Depression in Parkinson's DiseaseRecruitingNCT07610369Phase 21 country
- Brain Stimulation to Improvement After Cerebellar DamageNot yet recruitingNCT07838961Not applicable1 country
- Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle ControlRecruitingNCT07056361Not applicable1 country
- Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor FunctionRecruitingNCT07056348Not applicable1 country
- Natural History Protocol for Movement DisordersRecruitingNCT054132911 country
- A Trial of ONO-2808 in Participants With the Parkinsonian Subtype of Multiple System Atrophy (MSA-P)Not yet recruitingNCT07825402Phase 3
- ZEPU-AI Series Limb Feedback Robot Training Study (ZEPUAISRCT)RecruitingNCT07749625Not applicable1 country
- Neurodegenerative Diseases Progression Markers (MARKERS-NDD)RecruitingNCT065967461 country
- Biofluid Research on Age-Related or Inherited NeurodegenerationRecruitingNCT077987001 country
- rTMS as an Intervention for Levodopa-induced DyskinesiaRecruitingNCT06570824Not applicable1 country
- Transplantation of Human iPS Cell-derived Dopaminergic Progenitors (CT1-DAP001) for Parkinson's Disease (Phase I/II)RecruitingNCT06482268Phase 11 country
- Psilocybin Therapy for Depression in Parkinson's DiseaseRecruitingNCT06455293Phase 21 country
- Circadian Adaptive DBS in Essential TremorRecruitingNCT06635811Not applicable1 country
- Moderate Versus High Volume Light-Moderate Intensity Exercise for People With Moderate Parkinson's DiseaseRecruitingNCT06088355Not applicable1 country
- Motoneuron Recruitment and Motor Evoked Potential Up-Conditioning (MEP) in Spinal Cord Injury (SCI)RecruitingNCT07179822Not applicable1 country
- ZR001 Chemogenetics Gene Therapy Study in Patients With Parkinson's DiseaseNot yet recruitingNCT07718659Phase 11 country
- Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement DisordersRecruitingNCT06848530Not applicable1 country
- Pediatric Movement Disorders of Unknown Etiology in Vietnam (VPeMD)RecruitingNCT076956101 country
- Deutetrabenazine Treatment for Tardive Dyskinesia in Intellectual/Developmental DisabilitiesRecruitingNCT06997198Phase 41 country
- Effects of Targeted Temporal Interference Stimulation of Cerebellar Nuclei on Tremor and Gait Disturbance in Parkinson's Disease PatientsNot yet recruitingNCT07384442Not applicable1 country
- Stimulation-Based Modulation of Spinal and Cortical Sensory PathwaysRecruitingNCT07401186Not applicable1 country
- Behavioral Intervention for Lifestyle Physical Activity in Parkinson's DiseaseNot yet recruitingNCT06603012Not applicable1 country
- Dyadic Mindfulness for People With Parkinson's Disease and Their CaregiversRecruitingNCT06821230Not applicable1 country
- Cognitive Decline Following Deep Brain StimulationRecruitingNCT058223881 country
- Long-read Genome Sequencing for the Molecular Diagnosis of DystoniaRecruitingNCT06999096Not applicable1 country
- Open Label Study for the Use of Low Intensity Focused Ultrasound for Essential TremorRecruitingNCT07599592Early Phase 11 country
- Comparison of NeuroEXPLORER PET/CT Versus Standard-of-care PET/CT of the Head and Neck Region.Enrolling by invitationNCT07595666Not applicable1 country
- A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's DiseaseRecruitingNCT06826612Phase 1/21 country
- Validating a New Machine-Learned Accelerometer Algorithm Using Doubly Labeled WaterRecruitingNCT057363021 country
- Non-invasive BCI-controlled Assistive DevicesRecruitingNCT05183152Not applicable1 country
- Study of Axial and Cognitive Symptoms and Biomarkers of Neurodegeneration in Brain-first and Body-first PDRecruitingNCT071878431 country
- Deep Brain Stimulation (DBS) MatchMakerEnrolling by invitationNCT069128411 country
- Effects of Stimulation Patterns of Deep Brain StimulationEnrolling by invitationNCT02553525Not applicable1 country
- Cerebellar Research in Ultrasound StimulationNot yet recruitingNCT07508696Not applicable1 country