Endotoxemia clinical trials
The registry lists 84 studies for Endotoxemia across more than 10 countries. 8 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-07-20.
Status
- Completed
- 64
- Recruiting
- 6
- Status unknown
- 5
- Active, not recruiting
- 3
- Not yet recruiting
- 2
- Terminated
- 1
Phase
- Phase 1
- 12
- Phase 4
- 7
- Phase 2
- 3
- Early Phase 1
- 1
- Phase 3
- 1
Where
- Netherlands
- 21
- United States
- 15
- Denmark
- 11
- Austria
- 8
- Canada
- 4
- France
- 3
Who runs them
Radboud University Medical Center (21) · University of Aarhus (5) · Ohio State University (4) · Rigshospitalet, Denmark (4) · Spectral Diagnostics (US) Inc. (4) · Medical University of Vienna (3) · Laval University (3) · University of Vienna (3)
Studies
Recruiting first, then most recently updated. Showing 50 of 84 — search for more.
- Short-Chain Fatty Acids in Lypopolysaccharide-Induced Inflammation and Executive FunctionRecruitingNCT07713641Not applicable1 country
- Hemoadsorpion in Patients With Septic Shock: Efficacy and Safety EvaluationNot yet recruitingNCT07661303Not applicable1 country
- OxiCLEAR (Oxiris Cytokines and Endotoxin Adsorption Rate) StudyRecruitingNCT074198021 country
- Glucose Levels in Acute Pancreatitis and the Impact of Insulin Depletion and Bacterial EndotoxaemiaNot yet recruitingNCT06972238
- Different Dietary PatternsRecruitingNCT06147440Not applicable1 country
- Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human EndotoxemiaRecruitingNCT06624436Phase 41 country
- Efficacy and Safety of Hemoperfusion With Polymyxin B in Septic Shock Associated With Severe Endotoxemia in Cardiac Surgery Patients (РМХ vs SS)RecruitingNCT04920565Not applicable1 country
- The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive DisorderRecruitingNCT062030151 country
- Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label StudyActive, not recruitingNCT03901807Not applicable1 country
- Gut-level Antiinflammatory Activities of Green Tea in Metabolic SyndromeCompletedNCT03973996Not applicable1 country
- Assessing Gut Microbiota Mediated Health Outcomes of Whole Wheat and Its Major Bioactive ComponentsActive, not recruitingNCT05318183Not applicable1 country
- Synergistic Innovative Functional Food Concepts to Neutralize Inflammation for Cardiometabolic Risk PreventionCompletedNCT04190706Not applicable1 country
- Polyphenol Metabolism and Personalized Nutrition in Menopause (PolyPause).Active, not recruitingNCT07182370Not applicable1 country
- Cardiometabolic Benefits of Potatoes Mediated Along the Gut-Vessel Axis in Adults With Metabolic SyndromeCompletedNCT03624569Not applicable1 country
- Dietary Green Tea Confection For Resolving Gut Permeability-Induced Metabolic Endotoxemia In Obese AdultsCompletedNCT03413735Not applicable1 country
- Determining the Fingerprint of Endotoxin ToleranceCompletedNCT06801873Not applicable1 country
- Rifaximin in Cirrhosis: Effects on Endotoxin and Haemostatic IndexesTerminatedNCT06630572Phase 41 country
- Effects of Maple Syrup on Gut Microbiota Diversity and Metabolic SyndromeCompletedNCT04117802Not applicable1 country
- Elevated Levels of Antibodies to Endotoxin Core in Hemodialysis Patients With Peripheral Artery DiseaseCompletedNCT057529681 country
- Dietary Intervention to Reduce Metabolic EndotoxemiaCompletedNCT05776329Not applicable1 country
- Effects of Non-calorie Sweeteners, Mono- and Disaccharides on Intestinal Barrier FunctionCompletedNCT04788680Not applicable1 country
- Safety and Feasibility of an Endotoxemia ModelCompletedNCT01329965Phase 11 country
- Remove LPS RegistryWithdrawnNCT05260099
- Demonstration of the Prebiotic-like Effects of Camu-camu Consumption Against Obesity-related Disorders in HumansCompletedNCT04130321Not applicable1 country
- The Effect of Probiotics on Systemic Inflammation and Metabolic Endotoxemia in Patients Undergoing Bariatric SurgeryStatus unknownNCT05407090Not applicable1 country
- Evaluating the Use of Polymyxin B Cartridge Hemoperfusion for Patients With Septic Shock and COVID 19No longer availableNCT043529851 country
- Open-label Evaluation of Polymyxin B Hemoperfusion for Septic ShockTemporarily not availableNCT02825329
- The Effect of Probiotics on Obesity. Metabolic Endotoxemia and InflammationCompletedNCT03883685Not applicable1 country
- ENDOCUR - Modulation of Endotoxaemia Via Curcumin Intake in Healthy Overweight AdultsCompletedNCT03329781Not applicable
- Foodprint 1.0: Physiological Acute Responses After Consumption of Confectionary ProductsCompletedNCT03972878Not applicable1 country
- Investigating the Possible Link Between Habitual Diet, Physical Activity, Sleeping Patterns, Obesity Status and Age With Gut Bacterial Composition, Gut Barrier Function, Metabolic Endotoxemia, Systemic Inflammation and Glycaemic Control.Status unknownNCT038641071 country
- Cereals and Intestinal FunctionCompletedNCT04019457Not applicable1 country
- Echocardiographic Changes After 3-hydroxy Butyrate+Whey IntakeCompletedNCT04037722Not applicable1 country
- Gastro-intestinal and Hormonal Responses to Systemic Inflammatory DiseaseCompletedNCT04056286Not applicable1 country
- Anabolic Potential of 3-hydroxybutyrate (3-OHB) and Whey Protein in a Human Catabolic Inflammatory Disease ModelCompletedNCT04064268Not applicable1 country
- Effects of Cranberry Powder Supplements on Gut Microbiota Diversity and Metabolic SyndromeCompletedNCT03754504Not applicable1 country
- Vorapaxar in the Human Endotoxemia ModelCompletedNCT02875028Phase 41 country
- Defibrotide in the Human Endotoxemia Model --- an Exploratory Trial Investigating the Effects and the Mechanisms of DefibrotideCompletedNCT02876601Phase 41 country
- The Effects of Acetylsalicylic Acid on Immunoparalysis Following Human EndotoxemiaCompletedNCT02922673Not applicable1 country
- Role Of Phospholipid Transfer Proteins (Pltp) On Endotoxemia Caused By Buccal InflammationCompletedNCT01950962Not applicable1 country
- Whey vs Casein to Combat Post-inflammatory Protein and Muscle Waste in Acute DiseaseCompletedNCT03319550Not applicable1 country
- Effect of Monosaccharides on Intestinal Barrier FunctionCompletedNCT03482284Not applicable
- Effects of Cold Exposure and Breathing Techniques on Immune ResponseCompletedNCT03240497Not applicable1 country
- Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Septic ShockCompletedNCT01046669Not applicable2 countries
- A New Model of Acute Febrile DiseaseCompletedNCT03158363Not applicable1 country
- Sevelamer for Reducing Endotoxemia and Immune ActivationCompletedNCT01543958Phase 21 country
- The Association Between Microbiota, Endotoxaemia and the Host Obesity/ Insulin Resistance (MiPOOP Study)CompletedNCT036659611 country
- Effects of Vasopressors on Immune ResponseCompletedNCT02675868Phase 41 country
- PK/PD of EA-230 During EndotoxemiaCompletedNCT02629874Phase 11 country
- Effect of Gemigliptin on Metabolic Endotoxemia and LipemiaCompletedNCT02186080Not applicable1 country