Bacteremia clinical trials
The registry lists 297 studies for Bacteremia across more than 10 countries. 51 are recruiting or about to start. 184 of them are mainly about Bacteremia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Endotoxemia too: 377 studies, 58 open.
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Who runs them
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (8) · Assistance Publique - Hôpitaux de Paris (6) · Sunnybrook Health Sciences Centre (6) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (5) · Rambam Health Care Campus (5) · Fondation Hôpital Saint-Joseph (4) · University of Pittsburgh (4) · Pfizer (4)
What is being tested here
Drugs under test in Bacteremia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Linezolid | 1 | 2 | 3 |
| Penicillin G | 1 | 0 | 2 |
| Thiamine hydrochloride | 1 | 0 | 1 |
| Thiamine | 1 | 0 | 1 |
| Clindamycin | 1 | 0 | 1 |
| Doxycycline | 1 | 0 | 1 |
| Ertapenem | 1 | 0 | 1 |
| Beta-Lactams | 1 | 0 | 1 |
| Levofloxacin | 1 | 0 | 1 |
| Amdinocillin Pivoxil | 1 | 1 | 1 |
Drug classes tested here Beta-lactamase inhibitors 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Sep 2027Pivmecillinam With Amoxicillin/Clavulanic Acid for Step Down Oral Therapy in ESBL UTIs · Phase 3 · Lund University
- Nov 2026Impact of Real-time MIC (Minimum Inhibitory Concentration) Reporting (<6 Hours) on β-lactam Prescription in Cases of Gram-negative Bacilli Bacteremia in ICU Patients in Real-life Settings · Assistance Publique - Hôpitaux de Paris
- Dec 2026Improving Therapeutic Drug Monitoring and Dosing for Vancomycin in Young Infants With Infections (VANCAPP) (Part 2) · Murdoch Childrens Research Institute
- Dec 2026Clinical Efectiveness of a Multiplex PCR-Based Rapid Diagnostic Method in Bloodstream Infections · Istanbul Medipol University Hospital
- Jan 2027Blood Culture Collection Strategies for Suspected Bloodstream Infection · Izola General Hospital
- Jan 2027PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN) · Rambam Health Care Campus
- Apr 2027Combination Cefazolin With Ertapenem for Methicillin-susceptible Staphylococcus Aureus Bacteremia · Todd C. Lee MD MPH FIDSA
- Apr 2027Evaluation of Diagnostic Accuracy and Clinical Performance of the UllCORE Bloodstream Infection (BSI) Test · Deepull Diagnostics S.L.
- Apr 2027A Platform Trial for Gram Negative Bloodstream Infections · Sunnybrook Health Sciences Centre
- May 2027Examination of the Large Intestine With Camera Capsule in Patients With Blood Stream Infection With Gut-associated Bacteria · Odense University Hospital
Who these studies take
Of the 40 Bacteremia studies recruiting now, 32 (80%) set no upper age limit and 4 (10%) stop at 75 or younger. 11 (28%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (5%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 8 (20%) | 8 (20%) |
| 18 | 36 (90%) | 36 (90%) |
| 30 | 36 (90%) | 36 (90%) |
| 40 | 36 (90%) | 36 (90%) |
| 50 | 36 (90%) | 36 (90%) |
| 65 | 36 (90%) | 36 (90%) |
| 75 | 36 (90%) | 36 (90%) |
| 85 | 36 (90%) | 36 (90%) |
Across all 297 studies, recruiting or not: 12% stop at 75 or younger and 11% at 65; 27% take children; <1% are for women only and 0% for men only; 7% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Bacteremia studies take
Of 39 observational studies under Bacteremia, half reached primary completion within 21 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 34 mo13–64 · 35 studies | — | 34 mo13–64 · 34 studies |
| Observational | 21 mo11–38 · 39 studies | — | 21 mo11–41 · 32 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting3
- Oral Switch in Bloodstream Infections in Immunocompromised ChildrenNov 10, 2026NCT07923266
- Oral Switch in Pediatric Bloodstream InfectionsOct 19, 2026NCT07791914
- From Commensalism to Pathogenicity: Exploring the Pathophysiology of Bacteremia to Better Understand Enterococcus Faecalis Infective EndocarditisOct 13, 2026NCT07313865
Newly registered5
- Oral Switch in Bloodstream Infections in Immunocompromised ChildrenNov 6, 2026NCT07923266
- Evaluation of an AI-Assisted Tool for CLABSI Surveillance at VA Medical CentersNov 5, 2026NCT07918352
- Comparative Study of the Genomic Characteristics of Uropathogenic Escherichia Coli According to the Severity of Community-Acquired Urinary Tract Infections in Guadeloupe (COLIGENURI)Oct 29, 2026NCT07905638
- Middle East Study of Infections in Patients With Hematological MalignanciesOct 28, 2026NCT07900542
- Predicting the Optimal Empirical Antibiotic Therapy for Bacteremia Using an Artificial Intelligence-based ModelOct 26, 2026NCT07894237
Studies
Recruiting first, then most recently updated. Showing 50 of 297. Browse all 297 → or search them.
- Oral Switch in Bloodstream Infections in Immunocompromised ChildrenRecruitingNCT07923266Phase 41 country
- A Platform Trial for Gram Negative Bloodstream InfectionsRecruitingNCT06537609Not applicable5 countries
- Evaluation of an AI-Assisted Tool for CLABSI Surveillance at VA Medical CentersNot yet recruitingNCT07918352Not applicable
- Combination Cefazolin With Ertapenem for Methicillin-susceptible Staphylococcus Aureus BacteremiaRecruitingNCT04886284Phase 21 country
- Middle East Study of Infections in Patients With Hematological MalignanciesRecruitingNCT079005425 countries
- Comparative Study of the Genomic Characteristics of Uropathogenic Escherichia Coli According to the Severity of Community-Acquired Urinary Tract Infections in Guadeloupe (COLIGENURI)Not yet recruitingNCT07905638
- Oral Switch in Pediatric Bloodstream InfectionsRecruitingNCT07791914Phase 41 country
- From Commensalism to Pathogenicity: Exploring the Pathophysiology of Bacteremia to Better Understand Enterococcus Faecalis Infective EndocarditisRecruitingNCT07313865Not applicable1 country
- Impact of Blood Cultures Drawn From Arterial Lines on the Incidence of Contamination, Detection of Bacteremia, and Blood Culture VolumeRecruitingNCT071834101 country
- THiamine for Recovery In Vulnerable Early-life InfectionsNot yet recruitingNCT07868679Phase 21 country
- Evaluation of Diagnostic Accuracy and Clinical Performance of the UllCORE Bloodstream Infection (BSI) TestRecruitingNCT078598525 countries
- The Per-procedural Antibiotic Prophylaxis in Patients Undergoing Transcatheter Aortic Valve Implantation TrialRecruitingNCT07442357Not applicable2 countries
- Combination Antibiotic Therapy for Staphylococcus Aureus BacteremiaRecruitingNCT07376889Phase 41 country
- Dabigatran vs. Oral Anti-Xa Inhibitors in S. Aureus BacteremiaRecruitingNCT06650501Phase 41 country
- Does Staphylococcus Aureus Bacteremia Early Dual Therapy Improve Outcomes?Enrolling by invitationNCT07148960Phase 41 country
- Microbiology Operations & Time Optimization in SepsisNot yet recruitingNCT078170431 country
- Daptomycin vs. Vancomycin for the Treatment of Methicillin Resistant S. Aureus BacteremiaRecruitingNCT06637332Phase 43 countries
- Beta-lactam Plus Levofloxacin to Enhance Therapy in Streptococcal SepticemiaRecruitingNCT07240077Phase 41 country
- Cefepime/Enmetazobactam for Bacteremic Complicated Urinary Tract InfectionsNot yet recruitingNCT077258481 country
- Reducing Risk for Infective EndocarditisRecruitingNCT05721781Not applicable1 country
- Surveillance of AMR in DRCRecruitingNCT068212821 country
- Machine Learning Assisted Electrochemical Profiling to Provide Early Identification of Bloodstream Infections PathogensRecruitingNCT06853301Not applicable1 country
- Linezolid Plus Standard of CareRecruitingNCT06958835Not applicable1 country
- Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus BacteraemiaRecruitingNCT06726395Phase 41 country
- Improving Therapeutic Drug Monitoring and Dosing for Vancomycin in Young Infants With Infections (VANCAPP) (Part 2)RecruitingNCT05770622Phase 41 country
- Febrile Infants Swedish StudyRecruitingNCT071347511 country
- Structural and Microbiological Characterization of Arterial Catheter Biofilm in ICU's Patients Using Optical Coherence TomographyRecruitingNCT068385981 country
- Clinical Efectiveness of a Multiplex PCR-Based Rapid Diagnostic Method in Bloodstream InfectionsRecruitingNCT074085441 country
- Treatment of Enterococcus Faecalis BacteremRecruitingNCT072995391 country
- Echocardiography Versus no Echocardiography in S. Aureus Bacteraemia and VIRSTA Score < 3RecruitingNCT06457386Not applicable1 country
- Examination of the Large Intestine With Camera Capsule in Patients With Blood Stream Infection With Gut-associated BacteriaRecruitingNCT069190681 country
- Impact of Real-time MIC (Minimum Inhibitory Concentration) Reporting (<6 Hours) on β-lactam Prescription in Cases of Gram-negative Bacilli Bacteremia in ICU Patients in Real-life SettingsNot yet recruitingNCT07202377Not applicable
- Evaluation of the Systemic Burden of Non-surgical Periodontal Therapy: A Randomized Clinical Trial on Five Different Treatment ProtocolsRecruitingNCT07077122Not applicable1 country
- Prospective Validation of GRADY: A Machine Learning Model for Early Sepsis and Bacteremia Detection in ICU PatientsRecruitingNCT071261061 country
- Cefiderocol and Ampicillin-sulbactam vs. Colistin +/- Meropenem for Carbapenem Resistant A. BaumanniiRecruitingNCT05922124Phase 41 country
- PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN)RecruitingNCT03671967Phase 42 countries
- Outcomes of Empiric Antibiotic Therapy Based on Hospital Antibiograms in Organ Transplant Recipients with BacteraemiaEnrolling by invitationNCT068749201 country
- Cardiac Implantable Electronic Device RemOval Versus Full CoUrse Medical TreatmentRecruitingNCT06323668Not applicable1 country
- Fosfomycin I.v. for Treatment of Severely Infected PatientsRecruitingNCT029799515 countries
- Impact of Performing a Rapid Antibiotic Susceptibility Test on Antibiotic Therapy Adaptation in Adult Patients with Enterobacterales BacteremiaRecruitingNCT06425367Not applicable1 country
- Knowledge Attitude and Practice Regarding Bloodstream Bacterial Infections and Antibiotics Usage Among Doctors.Enrolling by invitationNCT066056771 country
- Identification and Validation of Clinical Phenotypes in Staphylococcus Aureus Bacteremia and Their Association With Mortality and Development of Complicated BacteremiaRecruitingNCT065743991 country
- Early Intravenous to Oral Antibiotic Switch in Uncomplicated Staphylococcus Aureus BacteraemiaRecruitingNCT06336824Phase 31 country
- An Oral Doxycycline Regimen to Prevent Bacteremia Following Dental ProceduresNot yet recruitingNCT06422221Phase 41 country
- the Safety and Efficacy of Intravitreal Injection of Tpdelansbsalbac in Malignant Effusions.RecruitingNCT06178003Not applicable1 country
- Evaluation of the Usefulness of Echocardiography in Patients With Staphylococcus Aureus Bacteremia (ET-AUREUS Study).RecruitingNCT05862025Not applicable1 country
- Exposure to Antibiotics and Incidence of Bacteraemia Caused by Resistant BacteriaNot yet recruitingNCT04065750
- Pivmecillinam With Amoxicillin/Clavulanic Acid for Step Down Oral Therapy in ESBL UTIsRecruitingNCT05224401Phase 31 country
- Short vs Long of Usual Treatment for Non Complicated Enterococcal BacteremiaRecruitingNCT05394298Phase 41 country
- Lebanese Interhospital Pneumococcal Surveillance ProgramRecruitingNCT009016021 country