Leprosy clinical trials
The registry lists 52 studies for Leprosy across more than 10 countries. 13 are recruiting or about to start. 46 of them are mainly about Leprosy (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.
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Who runs them
London School of Hygiene and Tropical Medicine (6) · Institute of Tropical Medicine, Belgium (4) · National Institute of Allergy and Infectious Diseases (NIAID) (3) · University of Sao Paulo (2) · University of Brasilia (2) · Aswan University (2) · Lo-Sheng Sanatorium (2) · The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz) (2)
What is being tested here
Drugs under test in Leprosy studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4, phase 3 first
- Mar 2027Bedaquiline Enhanced Post ExpOsure Prophylaxis for Leprosy · Phase 3 · Institute of Tropical Medicine, Belgium
- Dec 2026Epidemiological, Clinical, Diagnostic, and Therapeutic Characteristics of Hansen's Disease in Costa Rica (2018-2025) · Caja Costarricense de Seguro Social
- Dec 2026Accuracy of the Polymerase Chain Reaction of Ulnar Perineural Subcutaneous Aspirate Guided by Ultrasound for the Diagnosis and Monitoring of Leprosy Cure · University of Brasilia
- Feb 2027Integrating Mental Health Into Neglected Tropical Disease Care in Ghana · Liverpool School of Tropical Medicine
Who these studies take
Of the 7 Leprosy studies recruiting now, 3 (43%) set no upper age limit and 4 (57%) stop at 75 or younger. 4 (57%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (43%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (43%) | 3 (43%) |
| 18 | 6 (86%) | 6 (86%) |
| 30 | 7 (100%) | 7 (100%) |
| 40 | 7 (100%) | 7 (100%) |
| 50 | 7 (100%) | 7 (100%) |
| 65 | 5 (71%) | 5 (71%) |
| 75 | 3 (43%) | 3 (43%) |
| 85 | 3 (43%) | 3 (43%) |
Across all 52 studies, recruiting or not: 46% stop at 75 or younger and 42% at 65; 35% take children; 2% are for women only and 2% for men only; 35% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered1
- Telacebec in Adults With Multibacillary Leprosy (TEBULA Leprosy Trial)Nov 5, 2026NCT07918573
Studies
Recruiting first, then most recently updated. Showing 50 of 52. Browse all 52 → or search them.
- Telacebec in Adults With Multibacillary Leprosy (TEBULA Leprosy Trial)Not yet recruitingNCT07918573Phase 21 country
- Bedaquiline Enhanced Post ExpOsure Prophylaxis for LeprosyRecruitingNCT05597280Phase 31 country
- Accuracy of the Polymerase Chain Reaction of Ulnar Perineural Subcutaneous Aspirate Guided by Ultrasound for the Diagnosis and Monitoring of Leprosy CureRecruitingNCT07515989Not applicable1 country
- Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health WorkersNot yet recruitingNCT07506967Not applicable5 countries
- Epidemiological, Clinical, Diagnostic, and Therapeutic Characteristics of Hansen's Disease in Costa Rica (2018-2025)Not yet recruitingNCT074483891 country
- Integrating Mental Health Into Neglected Tropical Disease Care in GhanaNot yet recruitingNCT07248462Not applicable
- Novel Interventions and Diagnostic Tests for LeprosyRecruitingNCT06222372Not applicable1 country
- Efficacy and Tolerability of Adjunct Metformin for Multibacillary LeprosyRecruitingNCT05243654Phase 21 country
- Trauma-Informed Motivational Interviewing in Rural Dwelling SamplesRecruitingNCT06909734Not applicable1 country
- Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy PatientsRecruitingNCT06819449Not applicable1 country
- TGF β 1 Expression Related Gene PolymorphismRecruitingNCT066836901 country
- Trial LEP-F1 + GLA-SE in Healthy Adult in Areas Endemic for LeprosyNot yet recruitingNCT06627257Phase 11 country
- Phase 1b/2a Trial to Evaluate LEP-F1 + GLA-SE in Healthy Adults and Leprosy PatientsNot yet recruitingNCT03947437Phase 1/21 country
- Auricular Electroacupuncture and Auricular Acupuncture With Health Education for Pain in LeprosyCompletedNCT07862413Not applicable1 country
- Prednisolone Monotherapy Versus Prednisolone Plus Methotrexate in ENLCompletedNCT07806357Phase 11 country
- Leprosy Active Searching Trial in BrazilCompletedNCT06761469Not applicable1 country
- Potential Injection of Human Umbilical Cord Secretome in the Case of Trophic Ulcers (Pre-post Intervention)CompletedNCT05777213Phase 11 country
- Methotrexate and Prednisolone Study in Erythema Nodosum LeprosumActive, not recruitingNCT03775460Not applicable6 countries
- Post ExpOsure Prophylaxis for LEprosy in the Comoros and MadagascarCompletedNCT03662022Phase 32 countries
- Serum Irisin Level In Leprosy PatientsCompletedNCT064160331 country
- Bedaquiline Enhanced Post ExpOsure Prophylaxis for Leprosy (Phase 2)CompletedNCT05406479Phase 21 country
- Integrated Mapping of Skin-presenting Neglected Tropical Diseases in LiberiaCompletedNCT036837451 country
- The Effect of "Jinchuang Ointment" (JCO) on the Treatment of Wounds in Patients With Hansen's Disease.CompletedNCT05047809Not applicable1 country
- The Effects of Traditional Chinese Medicine Mouthwash Solutions on the Oral Health of Leprosy PatientsCompletedNCT05091216Not applicable1 country
- Treatment of Neuropathic Pain in LeprosyStatus unknownNCT03324035Phase 31 country
- Epidemiology of Leprosy in French GuianaStatus unknownNCT050310911 country
- Modified Tarsorrhaphy vs Gold Weight Implant for Paralytic Lagophthalmos in Leprosy PatientsCompletedNCT04944498Not applicable1 country
- Improved Understanding of Ongoing Transmission of Leprosy in the Hyperendemic Comoros (ComLep)CompletedNCT035267181 country
- Extramembranous and Interosseous Technique of Tibialis Posterior Tendon TransferTerminatedNCT01751503Not applicable1 country
- CC-11050 Trial in Nepalese Patients With Erythema Nodosum LeprosumStatus unknownNCT03807362Phase 21 country
- CD8 Reactivity to Microorganisms in Blood and Breast MilkTerminatedNCT030846141 country
- Phase 1 LEP-F1 + GLA-SE Vaccine Trial in Healthy Adult VolunteersCompletedNCT03302897Phase 11 country
- Uniform Multidrug Therapy Regimen for Leprosy PatientsCompletedNCT00669643Phase 41 country
- Virgin Coconut Oil Oral Supplementation for Leprosy PatientsWithdrawnNCT01885611Phase 1/21 country
- Low Level Laser Therapy Effects in Peripheral Nerves Patient With Leprosy.Status unknownNCT03072004Not applicable1 country
- Clinical Utility Of Genetic Screening For HLA-B*1301, On Susceptibility To Dapsone Hypersensitivity SyndromeStatus unknownNCT02550080Phase 41 country
- Effect of Weight and/or Obesity on Dapsone Drug ConcentrationsCompletedNCT01165840Phase 41 country
- Impact of the Virtual Human Project on Team-based Learning: A Randomized-controlled TrialCompletedNCT02484469Not applicable
- Effect of Additional Clofazimine on Erythema Nodosum Leprosum (ENL) Reactions in LeprosyCompletedNCT01290744Phase 41 country
- Treatment Protocol for Clofazamine in the Long Term Treatment of LeprosyNo longer availableNCT008523451 country
- Ciclosporin in the Management of Chronic or Recurrent Erythema Nodosum LeprosumCompletedNCT00919776Phase 21 country
- Ciclosporin in the Management of Steroid Resistant Type 1 Reactions in LeprosyCompletedNCT00919451Phase 21 country
- Ciclosporin in the Management of New Type 1 Reactions in LeprosyCompletedNCT00919815Phase 2/31 country
- Ciclosporin in the Management of New Erythema Nodosum LeprosumCompletedNCT00919542Phase 21 country
- Leprosy Skin Test Antigens TrialCompletedNCT00128193Phase 22 countries
- Molecular and Immunological Tools for Detection of Strain Diversity, Drug Resistance and Immunological ResponsesCompletedNCT001384371 country
- Leprosy Skin Test Antigens Phase 1CompletedNCT01920750Phase 1
- Microcirculatory Impairment in Patients With LeprosyCompletedNCT02085317Not applicable
- Molecular Epidemiology of Leprosy - PhilippinesCompletedNCT003158091 country
- The Use of Low Level Laser Therapy for Wound Healing in Leprosy PatientsCompletedNCT00860717Not applicable1 country