Leprosy clinical trials
The registry lists 51 studies for Leprosy across more than 10 countries. 12 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-08.
Status
- Completed
- 28
- Recruiting
- 7
- Status unknown
- 6
- Not yet recruiting
- 5
- Terminated
- 2
- Active, not recruiting
- 1
Phase
- Phase 2
- 11
- Phase 1
- 8
- Phase 3
- 4
- Phase 4
- 4
Where
- Brazil
- 11
- Ethiopia
- 6
- United States
- 5
- Indonesia
- 4
- Bangladesh
- 4
- Egypt
- 4
Who runs them
London School of Hygiene and Tropical Medicine (6) · Institute of Tropical Medicine, Belgium (4) · National Institute of Allergy and Infectious Diseases (NIAID) (3) · Colorado State University (2) · University of Brasilia (2) · University of Sao Paulo (2) · The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz) (2) · Aswan University (2)
Studies
Recruiting first, then most recently updated. Showing 50 of 51 — search for more.
- Bedaquiline Enhanced Post ExpOsure Prophylaxis for LeprosyRecruitingNCT05597280Phase 31 country
- Accuracy of the Polymerase Chain Reaction of Ulnar Perineural Subcutaneous Aspirate Guided by Ultrasound for the Diagnosis and Monitoring of Leprosy CureRecruitingNCT07515989Not applicable1 country
- Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health WorkersNot yet recruitingNCT07506967Not applicable5 countries
- Epidemiological, Clinical, Diagnostic, and Therapeutic Characteristics of Hansen's Disease in Costa Rica (2018-2025)Not yet recruitingNCT074483891 country
- Integrating Mental Health Into Neglected Tropical Disease Care in GhanaNot yet recruitingNCT07248462Not applicable
- Novel Interventions and Diagnostic Tests for LeprosyRecruitingNCT06222372Not applicable1 country
- Efficacy and Tolerability of Adjunct Metformin for Multibacillary LeprosyRecruitingNCT05243654Phase 21 country
- Trauma-Informed Motivational Interviewing in Rural Dwelling SamplesRecruitingNCT06909734Not applicable1 country
- Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy PatientsRecruitingNCT06819449Not applicable1 country
- TGF β 1 Expression Related Gene PolymorphismRecruitingNCT066836901 country
- Trial LEP-F1 + GLA-SE in Healthy Adult in Areas Endemic for LeprosyNot yet recruitingNCT06627257Phase 11 country
- Phase 1b/2a Trial to Evaluate LEP-F1 + GLA-SE in Healthy Adults and Leprosy PatientsNot yet recruitingNCT03947437Phase 1/21 country
- Prednisolone Monotherapy Versus Prednisolone Plus Methotrexate in ENLCompletedNCT07806357Phase 11 country
- Leprosy Active Searching Trial in BrazilCompletedNCT06761469Not applicable1 country
- Potential Injection of Human Umbilical Cord Secretome in the Case of Trophic Ulcers (Pre-post Intervention)CompletedNCT05777213Phase 11 country
- Methotrexate and Prednisolone Study in Erythema Nodosum LeprosumActive, not recruitingNCT03775460Not applicable6 countries
- Post ExpOsure Prophylaxis for LEprosy in the Comoros and MadagascarCompletedNCT03662022Phase 32 countries
- Serum Irisin Level In Leprosy PatientsCompletedNCT064160331 country
- Bedaquiline Enhanced Post ExpOsure Prophylaxis for Leprosy (Phase 2)CompletedNCT05406479Phase 21 country
- Integrated Mapping of Skin-presenting Neglected Tropical Diseases in LiberiaCompletedNCT036837451 country
- The Effects of Traditional Chinese Medicine Mouthwash Solutions on the Oral Health of Leprosy PatientsCompletedNCT05091216Not applicable1 country
- The Effect of "Jinchuang Ointment" (JCO) on the Treatment of Wounds in Patients With Hansen's Disease.CompletedNCT05047809Not applicable1 country
- A Study to Evaluate the Efficacy and Safety of Bedaquiline (TMC207) in Participants With Multibacillary LeprosyCompletedNCT03384641Phase 21 country
- Treatment of Neuropathic Pain in LeprosyStatus unknownNCT03324035Phase 31 country
- Epidemiology of Leprosy in French GuianaStatus unknownNCT050310911 country
- Modified Tarsorrhaphy vs Gold Weight Implant for Paralytic Lagophthalmos in Leprosy PatientsCompletedNCT04944498Not applicable1 country
- Improved Understanding of Ongoing Transmission of Leprosy in the Hyperendemic Comoros (ComLep)CompletedNCT035267181 country
- Extramembranous and Interosseous Technique of Tibialis Posterior Tendon TransferTerminatedNCT01751503Not applicable1 country
- CC-11050 Trial in Nepalese Patients With Erythema Nodosum LeprosumStatus unknownNCT03807362Phase 21 country
- CD8 Reactivity to Microorganisms in Blood and Breast MilkTerminatedNCT030846141 country
- Phase 1 LEP-F1 + GLA-SE Vaccine Trial in Healthy Adult VolunteersCompletedNCT03302897Phase 11 country
- Uniform Multidrug Therapy Regimen for Leprosy PatientsCompletedNCT00669643Phase 41 country
- Virgin Coconut Oil Oral Supplementation for Leprosy PatientsWithdrawnNCT01885611Phase 1/21 country
- Low Level Laser Therapy Effects in Peripheral Nerves Patient With Leprosy.Status unknownNCT03072004Not applicable1 country
- Clinical Utility Of Genetic Screening For HLA-B*1301, On Susceptibility To Dapsone Hypersensitivity SyndromeStatus unknownNCT02550080Phase 41 country
- Effect of Weight and/or Obesity on Dapsone Drug ConcentrationsCompletedNCT01165840Phase 41 country
- Impact of the Virtual Human Project on Team-based Learning: A Randomized-controlled TrialCompletedNCT02484469Not applicable
- Effect of Additional Clofazimine on Erythema Nodosum Leprosum (ENL) Reactions in LeprosyCompletedNCT01290744Phase 41 country
- Treatment Protocol for Clofazamine in the Long Term Treatment of LeprosyNo longer availableNCT008523451 country
- Ciclosporin in the Management of Chronic or Recurrent Erythema Nodosum LeprosumCompletedNCT00919776Phase 21 country
- Ciclosporin in the Management of Steroid Resistant Type 1 Reactions in LeprosyCompletedNCT00919451Phase 21 country
- Ciclosporin in the Management of New Type 1 Reactions in LeprosyCompletedNCT00919815Phase 2/31 country
- Ciclosporin in the Management of New Erythema Nodosum LeprosumCompletedNCT00919542Phase 21 country
- Leprosy Skin Test Antigens TrialCompletedNCT00128193Phase 22 countries
- Molecular and Immunological Tools for Detection of Strain Diversity, Drug Resistance and Immunological ResponsesCompletedNCT001384371 country
- Leprosy Skin Test Antigens Phase 1CompletedNCT01920750Phase 1
- Microcirculatory Impairment in Patients With LeprosyCompletedNCT02085317Not applicable
- Molecular Epidemiology of Leprosy - PhilippinesCompletedNCT003158091 country
- The Use of Low Level Laser Therapy for Wound Healing in Leprosy PatientsCompletedNCT00860717Not applicable1 country
- Prevention of Disability: Proposal for a Guidance Manual for Leprosy PatientsCompletedNCT01006759Phase 11 country