Drug
Clofazimine clinical trials
Also written Lamprene.
- studies test it
- 23
- open now
- 3
- in phase 3
- 8
- first study started
- 1994
Keep track of what changes. Save the Clofazimine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
- CFZ
- 2
Brand
Studies by the year they started
20 studies that test it; most in 2020 (4); 1 more planned to start later
| Year | Studies |
|---|---|
| 1994 | 1 |
| 2010 | 1 |
| 2012 | 1 |
| 2016 | 2 |
| 2017 | 2 |
| 2018 | 1 |
| 2019 | 1 |
| 2020 | 4 |
| 2021 | 2 |
| 2022 | 2 |
| 2023 | 1 |
| 2024 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 1
- Phase 2
- 14
- Phase 3
- 8
- Phase 4
- 1
- No phase
- 3
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 1 · Other 22
Huashan Hospital (2) · Médecins Sans Frontières, France (2) · Medecins Sans Frontieres, Netherlands (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · The University of Queensland (2) · Brigham and Women's Hospital (1) · Boston University (1) · Oregon Health and Science University (1)
Often tested with
Tested in the same studies.
Bedaquiline (12) · Linezolid (9) · OPC-67683 (5) · Levofloxacin (5) · Moxifloxacin (4) · Pyrazinamide (4) · Ethambutol (4) · Amikacin (4)
Studies
Open first, then newest update. How each study uses Clofazimine is read from its arms, and is right about nine times in ten.
Testing it · 23
- Bacteriophage Therapy for Mycobacterium Abscessus Pulmonary InfectionEnrolling by invitationPhase 1Vancouver Coastal HealthNCT07228702Written as Clofazimine
- Finding the Optimal Regimen for Mycobacterium Abscessus TreatmentRecruitingPhase 2/3The University of QueenslandNCT04310930Written as Clofazimine
- Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform TrialNot yet recruitingPhase 2The University of QueenslandNCT07485010Written as Clofazimine
- Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard Therapy for Drug-Susceptible TuberculosisActive, not recruitingPhase 2Brigham and Women's HospitalNCT05556746Written as Clofazimine (CFZ)
- Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and Clofazimine to Treat MDR-TBActive, not recruitingPhase 2Boston UniversityNCT03828201Written as Clofazimine
- Clofazimine- and Rifapentine-Containing Treatment Shortening Regimens in Drug-Susceptible Tuberculosis: The CLO-FAST StudyTerminatedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT04311502Written as Clofazimine 100 MG
- Clofazimine in the Treatment of Pulmonary Mycobacterium Avium Complex (MAC)Active, not recruitingPhase 2Oregon Health and Science UniversityNCT02968212Written as Clofazimine
- Innovating Shorter, All- Oral, Precised Treatment Regimen for Rifampicin Resistant Tuberculosis：BDLL Chinese CohortActive, not recruitingPhase 3Huashan HospitalNCT06649721Written as Clofazimine
- Evaluating Newly Approved Drugs for Multidrug-resistant TBCompletedPhase 3Médecins Sans Frontières, FranceNCT02754765Written as Clofazimine
- Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q)CompletedPhase 3Médecins Sans Frontières, FranceNCT03896685Written as Clofazimine 100 MG Oral Capsule
- Refining MDR-TB Treatment (T) Regimens (R) for Ultra(U) Short(S) Therapy(T)-PLUSCompletedNot applicableHuashan HospitalNCT04717908Written as Clofazimine
- Economic Evaluation of New MDR TB RegimensCompletedPhase 2/3Medecins Sans Frontieres, NetherlandsNCT04207112Written as Clofazimine
- The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TBCompletedPhase 3IUATLD, IncNCT02409290Written as Clofazimine
- Pharmacokinetic Study With a Loading Dose of Clofazimine in Adult Patients With Nontuberculous Mycobacterial DiseaseCompletedPhase 2Radboud University Medical CenterNCT05294146Written as Clofazimine
- Two-month Regimens Using Novel Combinations to Augment Treatment Effectiveness for Drug-sensitive TuberculosisCompletedPhase 2/3University College, LondonNCT03474198Written as Clofazimine
- A Phase II/III Trial of Rifampin, Ciprofloxacin, Clofazimine, Ethambutol, and Amikacin in the Treatment of Disseminated Mycobacterium Avium Infection in HIV-Infected Individuals.CompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT00000641Written as Clofazimine
- PRACTECAL-PKPD Sub StudyStatus unknownPhase 2/3Medecins Sans Frontieres, NetherlandsNCT04081077Written as Clofazimine
- Dual Therapy With Interferon Beta-1b and Clofazimine for COVID-19Status unknownPhase 2The University of Hong KongNCT04465695Written as Clofazimine
- A Phase 2A Evaluation of the Safety, Tolerability, Pharmacokinetics, Efficacy of Clofazimine (CFZ) in CryptosporidiosisTerminatedPhase 2University of WashingtonNCT03341767Written as Clofazimine
- Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z)CompletedPhase 2Global Alliance for TB Drug DevelopmentNCT01691534Written as clofazimine (C)
See all 23 studies that test Clofazimine →
Given in every arm · 5 — Clofazimine is usual care beside what is tested
- A Study of an Oral Short-course Regimen Including Bedaquiline for the Treatment of Participants With Multidrug-resistant Tuberculosis in ChinaRecruitingPhase 4Beijing Chest HospitalNCT05306223Written as Clofazimine
- Linezolid Dosing Strategies in Drug-Resistant TBCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT05007821Written as Clofazimine 300 mg
- Innovating Shorter, All- Oral, Precised, Individualized Treatment Regimen for Rifampicin Resistant Tuberculosis：Contezolid, Delamanid and Bedaquiline CohortActive, not recruitingPhase 3Beijing Chest HospitalNCT06081361Written as Clofazimine
- Building Evidence for Advancing New Treatment for Rifampicin Resistant Tuberculosis (RR-TB) Comparing a Short Course of Treatment (Containing Bedaquiline, Delamanid and Linezolid) With the Current South African Standard of CareCompletedPhase 3Wits Health Consortium (Pty) LtdNCT04062201Written as Clofazimine Oral Product
- Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s)CompletedPhase 2/3Medecins Sans Frontieres, NetherlandsNCT02589782Written as Clofazimine
As the comparator · 2 — what is tested is compared with Clofazimine
- 6 Months of Bedaquiline(BDQ), Delamanid(DLM), Linezolid(LZD) and Levofloxacin(LFX) in RR-TB Patients in Hubei ProvinceNot yet recruitingNot applicableWuhan Pulmonary HospitalNCT07198685Written as Clofazimine
- A Study on the Short-course Treatment Regimen Containing Pretomanid for Drug-resistant TuberculosisNot yet recruitingNot applicableWuhan Pulmonary HospitalNCT07126639Written as clofazimine
Codes
What other systems call Clofazimine · ClinicalTrials.gg INT007230
- MeSH (NLM) D002991ClofazimineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) D959AE5USFCLOFAZIMINEConfirmed FDA, NLM, Wikidata
- RxNorm 2592Confirmed FDA, Wikidata
- Wikidata Q105302601(E/Z)-clofazimineConfirmed FDA, NLM, Wikidata
- Wikidata Q418611clofazimineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C47456ClofazimineOne source FDA
- DrugBank DB00845One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D002991 | Clofazimine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | D959AE5USF | CLOFAZIMINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 2592 | — | Confirmed FDA, Wikidata |
| Wikidata | Q105302601 | (E/Z)-clofazimine | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q418611 | clofazimine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C47456 | Clofazimine | One source FDA |
| DrugBank | DB00845 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.