Drug
Cyclosporine clinical trials
Also written Ciclosporin, Sandimmune, Neoral and 27-400.
Includes 1 study of (melle-4)cyclosporin.
- studies test it
- 398
- open now
- 32
- in phase 3
- 72
- first study started
- 1990
Keep track of what changes. Save the Cyclosporine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
390 studies that test it; most in 2006 (26)
| Year | Studies |
|---|---|
| 1990 | 1 |
| 1995 | 3 |
| 1996 | 4 |
| 1997 | 7 |
| 1998 | 7 |
| 1999 | 10 |
| 2000 | 14 |
| 2001 | 10 |
| 2002 | 16 |
| 2003 | 12 |
| 2004 | 25 |
| 2005 | 18 |
| 2006 | 26 |
| 2007 | 20 |
| 2008 | 10 |
| 2009 | 16 |
| 2010 | 19 |
| 2011 | 11 |
| 2012 | 16 |
| 2013 | 8 |
| 2014 | 13 |
| 2015 | 13 |
| 2016 | 5 |
| 2017 | 11 |
| 2018 | 6 |
| 2019 | 8 |
| 2020 | 25 |
| 2021 | 12 |
| 2022 | 9 |
| 2023 | 7 |
| 2024 | 4 |
| 2025 | 14 |
| 2026 | 10 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 6
- Phase 1
- 80
- Phase 2
- 165
- Phase 3
- 72
- Phase 4
- 82
- No phase
- 26
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 113 · Other 285
Fred Hutchinson Cancer Center (28) · Novartis Pharmaceuticals (18) · National Heart, Lung, and Blood Institute (NHLBI) (15) · Hoffmann-La Roche (8) · Masonic Cancer Center, University of Minnesota (8) · National Cancer Institute (NCI) (8) · Wyeth is now a wholly owned subsidiary of Pfizer (7) · Novartis (7)
Often tested with
Tested in the same studies.
Mycophenolic Acid (75) · Fludarabine (49) · Tacrolimus (45) · Cyclophosphamide (38) · Fludarabine phosphate (32) · Methotrexate (31) · Antilymphocyte Serum (26) · Sirolimus (22)
Studies
Open first, then newest update. How each study uses Cyclosporine is read from its arms, and is right about nine times in ten.
Testing it · 398
- TRACK-TBI Precision Medicine Part 3 - Option IIEnrolling by invitationPhase 2University of California, San FranciscoNCT06790095Written as Cyclosporine (CsA)
- Rituximab Plus Cyclosporine in Idiopathic Membranous NephropathyRecruitingPhase 2National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT00977977Written as Oral Cyclosporine
- Osimertinib and Cyclosporine A to Enhance Antitumor Efficacy in NSCLCRecruitingPhase 2NYU Langone HealthNCT07874490Written as Cyclosporine A (CsA)
- A Study to Investigate the Effect of Omeprazole and Cyclosporine on Velzatinib in Healthy ParticipantsNot yet recruitingPhase 1GlaxoSmithKlineNCT07862114Written as Cyclosporine
- Feasibility Pilot Sequential Multiple Assignment Randomized Trial (SMART) for Acute Severe Ulcerative ColitisRecruitingPhase 4Berinstein, JeffreyNCT05867329Written as Cyclosporine Injection (IV)
- Study to Improve OS in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus MMF Prophylaxis of GvHD in Allografted Patients in First CRRecruitingPhase 2/3University Hospital, AngersNCT02416388Written as Cyclosporine
- Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder ArthroplastyRecruitingPhase 2NYU Langone HealthNCT07138898Written as Cyclosporine
- 211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute LeukemiaRecruitingPhase 1/2Fred Hutchinson Cancer CenterNCT03128034Written as Cyclosporine
- Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or Pegfilgrastim Biosimilar in Treating Patients With Aplastic Anemia or Low or Intermediate-Risk Myelodysplastic SyndromeRecruitingPhase 2M.D. Anderson Cancer CenterNCT01624805Written as Cyclosporine
- Efficacy of Vevye Ophthalmic Solution for the Treatment of Meibomian Gland DysfunctionRecruitingPhase 4University of Alabama at BirminghamNCT07224529Written as Vevye(Cyclosporine 0.1% Ophthalmic Solution)
- Fungal Ulcer Treatment Augmented With Natamycin and Cyclosporine ARecruitingPhase 3University of California, San FranciscoNCT06658002Written as Cyclosporine A
- Utilization of a Microdevice for Psoriasis and Atopic DermatitisNot yet recruitingPhase 4University of California, San FranciscoNCT07352566Written as Cyclosporine
- Comparison of Conjunctival Goblet Cell Density in Dry Eye Patients Treated With Cyclosporine 0.1% Dissolved in Perfluorobutylpentane (Vevye®) or Generic 0.05% Cyclosporine Emulsion for 8 WeeksNot yet recruitingPhase 4Baylor College of MedicineNCT07368595Written as Vevye®
- Cord Blood Transplantation in Children and Young Adults With Blood CancerRecruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT07566377Written as Cyclosporine
- Methods of T Cell Depletion Trial (MoTD)RecruitingPhase 2University of BirminghamNCT04888741Written as Cyclosporine
- The Effect of 0.1% Topical Ciclosporin A for 12-weeks on the Eye Surface Immune Cells in Dry EyesRecruitingNot applicableThe University of New South WalesNCT06898853Written as 0.1% Ciclosporin A eye drops
- Cyclosporine In Takotsubo SyndromeRecruitingPhase 2University Hospital HeidelbergNCT05946772Written as Cyclosporine A
- CsA+EPAG/HPAG+Romiplostim N01 in Newly-diagnosed SAA/TD-NSAANot yet recruitingPhase 2Peking Union Medical College HospitalNCT07558434Written as Cyclosporine (CsA)
- Vevye + Flarex Combination Therapy for Dry EyeEnrolling by invitationPhase 4Canyon City EyecareNCT07553455Written as Vevye(Cyclosporine 0.1% Ophthalmic Solution)
- Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant DisordersRecruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT04644016Written as Cyclosporine-A
See all 398 studies that test Cyclosporine →
Given in every arm · 156 — Cyclosporine is usual care beside what is tested
- Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)RecruitingPhase 2Fred Hutchinson Cancer CenterNCT03970096Written as Cyclosporine
- CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic LeukemiaRecruitingPhase 1Fred Hutchinson Cancer CenterNCT04375631Written as Cyclosporine
- Ciclosporin Followed by Low-dose IL-2 in Patients With Recently Diagnosed Type 1 DiabetesRecruitingPhase 2Assistance Publique - Hôpitaux de ParisNCT05153070Written as Cyclosporin
- A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive MedicationsRecruitingPhase 3Bristol-Myers SquibbNCT04877288Written as Cyclosporine A
- Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic DiseasesRecruitingPhase 2Fred Hutchinson Cancer CenterNCT06013423Written as Cyclosporine
- Efficacy and Safety of Anti-CD25 rhMAb in the Treatment of Steroid-Refractory cGVHDNot yet recruitingPhase 4Peking University People's HospitalNCT06364319Written as Cyclosporine
- rhTPO + CsA vs CsA in the Treatment of LR-MDS With ThrombocytopeniaNot yet recruitingPhase 3Peking Union Medical College HospitalNCT07653581Written as Cyclosporine (CsA)
- Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological MalignanciesRecruitingPhase 2Fred Hutchinson Cancer CenterNCT04195633Written as Cyclosporine
- Enarodustat + CsA vs CsA in Newly Diagnosed TD-NSAANot yet recruitingPhase 3Peking Union Medical College HospitalNCT07548671Written as Cyclosporine (CsA)
- A Study of Romiplostim N01 Plus IST vs. Placebo Plus IST for Treatment-Naive Severe Aplastic AnemiaNot yet recruitingPhase 3Qilu Pharmaceutical Co., Ltd.NCT07345000Written as Cyclosporine A (CsA)
- Efficacy of 0.05% Cyclosporine A Eye Drops Combined With Absorbable Tear Duct Plugs in the Treatment of Dry Eye in Sjögren's SyndromEnrolling by invitationNot applicableTianjin Eye HospitalNCT07171710Written as 0.05% Cyclosporine Eye Drops
- Efficacy and Safety of rhTPO in Combination With Cyclosporine Versus Cyclosporine Alone in the Treatment of TD-NSAANot yet recruitingPhase 4Peking Union Medical College HospitalNCT06525948Written as Cyclosporin A
- Cyclosporine and Intense Pulsed Light for Dry Eye in Contact Lens UsersRecruitingPhase 3Université de SherbrookeNCT06392438Written as CycloSPORINE Ophthalmic
- Efficacy and Safety of CsA+AVA in the Treatment of NSAA in the ElderlyRecruitingPhase 2Peking Union Medical College HospitalNCT06004752Written as Ciclosporin
- Romiplostim in Combination With CsA vs. CsA in the Treatment of Newly Diagnosed NSAANot yet recruitingPhase 4Peking Union Medical College HospitalNCT06009497Written as Ciclosporin
- Outcomes of Patients After Allo-HSCT With Decitabine and NACNot yet recruitingPhase 3The First Affiliated Hospital of Soochow UniversityNCT04945096Written as Cyclosporin A
- A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)TerminatedPhase 3Boston Children's HospitalNCT05600426Written as cyclosporine
- A Study in Healthy Men to Find Out How Blocking Certain Transport Proteins Affects the Amount of BI 3000202 in the BloodActive, not recruitingPhase 1Boehringer IngelheimNCT07774325Written as Ciclosporin
- A Phase II Dose-escalation Study Characterizing the PK of Eltrombopag in Pediatric Patients With Previously Untreated or Relapsed Severe Aplastic Anemia or Recurrent Aplastic AnemiaCompletedPhase 2Novartis PharmaceuticalsNCT03025698Written as CsA
- Luspatercept Plus CsA vs CsA for the Treatment of Newly Diagnosed Non-Transfusion-Dependent NSAAWithdrawnPhase 4Peking Union Medical College HospitalNCT06424639Written as cyclosporine
Showing 20 of 156.
As the comparator · 69 — what is tested is compared with Cyclosporine
- Evaluation of the Efficacy of Zuberitamab Injection in Patients With Primary Membranous NephropathyNot yet recruitingPhase 3BioRay Pharmaceutical Co., Ltd.NCT07830433Written as Cyclosporine
- A Clinical Study of B007 in the Treatment of Primary Membranous Nephropathy.RecruitingPhase 2/3Shanghai Jiaolian Drug Research and Development Co., LtdNCT06470191Written as Cyclosporin Capsules
- A Study to Compare the Effectiveness and Safety of T1695 Versus Ciclosporin in Participants With Moderate to Severe Vernal KeratoconjunctivitisRecruitingPhase 2Laboratoires TheaNCT07169695Written as Ciclosporin
- Cyclosporine Vs Steroids in DRESSEnrolling by invitationEarly Phase 1University of Southern CaliforniaNCT04988256Written as Cyclosporine
- Evaluation of Safety & Efficacy for the Prevention of Ocular GVHD With Ophthalmic Tacrolimus vs Cyclosporine in Allo-HSCTRecruitingPhase 1/2Hospital Universitario Dr. Jose E. GonzalezNCT06348602Written as Cyclosporine ophthalmic solution 0.1%
- A Randomized Controlled Study of High-dose Cyclophosphamide Induction Therapy in Adult Patients With HLHRecruitingNot applicableshifeng LouNCT05936086Written as Cyclosporine (CSA)
- Tofacitinib Versus Cyclosporine for Steroid Refractory Acute Severe Ulcerative ColitisNot yet recruitingNot applicablePost Graduate Institute of Medical Education and Research, ChandigarhNCT05112263Written as Cyclosporine
- Outcomes With Treatment and Withdraw of Secukinumab in Patients With Plaque PsoriasisNot yet recruitingPhase 4Singapore General HospitalNCT04239859Written as Cyclosporin A
- Outcomes With Treatment and Withdraw of Ixekizumab in Patients With Plaque PsoriasisRecruitingPhase 4Singapore General HospitalNCT04537689Written as Cyclosporin A
- Comparison of Efficacy and Safety of Treatment With a Calcineurin Inhibitor (CNI)Versus a CNI-free Treatment in Renal Transplantation (CIME)CompletedPhase 3Centre Hospitalier Universitaire, AmiensNCT01595984Written as cyclosporin + mycophenolate mofetil
- Rebamipide Versus Diquafosol and Cyclosporine for Perioperative Dry Eye in Cataract SurgeryCompletedPhase 4Samsung Medical CenterNCT07397936Written as Cyclosporine 0.05% ophthalmic solution
- Safety And Effectiveness Of The TearCare® System In The Treatment Of The Signs And Symptoms Of Dry Eye Disease (SAHARA)CompletedNot applicableSight Sciences, Inc.NCT04795752Written as Cyclosporine Ophthalmic 0.05% Ophthalmic Emulsion
- A Phase II Study of Zuberitamab Injection in Patients With Primary Membranous NephropathyActive, not recruitingPhase 2BioRay Pharmaceutical Co., Ltd.NCT06642909Written as cyclosporine
- A Phase Ib/ Ⅱ Clinical Study of MIL62 in Primary Membranous NephropathyCompletedPhase 1/2Beijing Mabworks Biotech Co., Ltd.NCT05398653Written as Cyclosporine
- Study of Methotrexate Efficacy Versus Cyclosporine in Moderate to Severe Atopic Dermatitis PatientsCompletedPhase 3Hospices Civils de LyonNCT00809172Written as Ciclosporin
- Mycophenolate Mofetil in Patients With Progressive Idiopathic Membranous NephropathyCompletedPhase 3Kyungpook National University HospitalNCT01282073Written as Cyclosporin, low dose steroid
- A Phase Ⅲ Clinical Study of MIL62 in Primary Membranous NephropathyActive, not recruitingPhase 3Beijing Mabworks Biotech Co., Ltd.NCT05862233Written as Cyclosporine
- A Research Study To See How Well an Eye Drop, SURF-100 (A Mycophenolic Acid/Betamethasone Sodium Phosphate Combination), Works and What Side Effects There Are in Subjects With Dry Eye DiseaseCompletedPhase 2Surface Ophthalmics, Inc.NCT04734197Written as Cyclosporine 0.05% Ophthalmic Emulsion
- Prevention of Skin Cancer in High Risk Patients After Conversion to a Sirolimus-based Immunosuppressive ProtocolTerminatedPhase 4Charite University, Berlin, GermanyNCT00866684Written as Ciclosporin
- HU007 in Patients with Dry Eye SyndromeCompletedPhase 3Huons Co., Ltd.NCT05743764Written as Restasis
Showing 20 of 69.
Codes
What other systems call Cyclosporine · ClinicalTrials.gg INT008533
- MeSH (NLM) D016572CyclosporineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 83HN0GTJ6DCYCLOSPORINEConfirmed FDA, NLM, Wikidata
- RxNorm 3008Confirmed FDA, Wikidata
- Wikidata Q367700cyclosporineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C406CyclosporineOne source FDA
- DrugBank DB00091One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D016572 | Cyclosporine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 83HN0GTJ6D | CYCLOSPORINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 3008 | — | Confirmed FDA, Wikidata |
| Wikidata | Q367700 | cyclosporine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C406 | Cyclosporine | One source FDA |
| DrugBank | DB00091 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.