Hyperalgesia clinical trials
The registry lists 152 studies for Hyperalgesia across more than 10 countries. 13 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-24.
Status
- Completed
- 100
- Status unknown
- 22
- Terminated
- 10
- Recruiting
- 8
- Withdrawn
- 5
- Not yet recruiting
- 3
Phase
- Phase 4
- 25
- Phase 2
- 25
- Phase 1
- 17
- Phase 3
- 12
- Early Phase 1
- 5
Where
- United States
- 38
- Denmark
- 17
- France
- 13
- China
- 10
- United Kingdom
- 7
- Korea, Republic of
- 7
Who runs them
Rigshospitalet, Denmark (10) · Aalborg University (5) · University Hospital, Basel, Switzerland (4) · Medical University of Vienna (4) · University Hospital, Clermont-Ferrand (4) · University Hospital, Bordeaux (4) · Stanford University (3) · Seoul National University Hospital (3)
Studies
Recruiting first, then most recently updated. Showing 50 of 152 — search for more.
- Open-Label Safety Study of AXS-14 in Subjects With FibromyalgiaEnrolling by invitationNCT07637162Phase 31 country
- Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research DesignRecruitingNCT07398417Phase 31 country
- Perioperative Quantitative Sensory Testing and Incision Pain Mapping in Thoracic SurgeryNot yet recruitingNCT076539321 country
- FROST-STERN Trial: A Trial of Intraoperative Cryoablation for Post Operative Pain Management After Full SternotomyNot yet recruitingNCT07637370Not applicable1 country
- Post-operative Analgesic Effect of Oral NefopamRecruitingNCT04576078Phase 21 country
- Music Therapy During Hypothermia in the NICUNot yet recruitingNCT06951269Not applicable1 country
- Neurosensorial Disorder and Pain in Oral Cavity and Oropharynx Cancer Traited Patients (OCAPA)RecruitingNCT04673981Not applicable1 country
- Response Profiles to High-concentration Capsaicin Desensitization in Patients with Peripheral Neuropathic Pain with or Without Allodynia: a Regional Multicenter Prospective CohortRecruitingNCT058175911 country
- Survey for Parental Perception of Procedural Analgosedation in Pediatric Age.RecruitingNCT067948791 country
- Investigation on the Status Quo of Hyperalgesia in Patients After Thoracoscopic Operation and Study on the Effect of Intraoperative InterventionRecruitingNCT06790914Not applicable1 country
- Safety and Efficacy Evaluation of S (+) - Ketamine in ChildrenEnrolling by invitationNCT04834427Phase 41 country
- Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal DeformationsRecruitingNCT04697498Not applicable1 country
- Electroacupuncture Pain Treatment, Mechanical Hyperalgesia, Quality of Life & Expression of Mu+ B Cells in FibromyalgiaRecruitingNCT053571571 country
- Impact of Repeatedly-Administered THC-cannabis on Experimental Pain and Abuse Liability in HumansSuspendedNCT04596644Phase 21 country
- Dextromethorphan Effect on Central Sensitization to Pain in Healthy VolunteersCompletedNCT02596360Phase 11 country
- Effect of Ultra-low Dose Naloxone on Remifentanil-Induced HyperalgesiaTerminatedNCT03066739Phase 21 country
- Session-Order Sensitivity of TS and OA in a Capsaicin Crossover ModelCompletedNCT07625475Not applicable1 country
- STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic PancreatitisActive, not recruitingNCT05603702Phase 11 country
- Local Anesthetic Infiltration to Prevent Postoperative Pain After Lumbar SurgeryCompletedNCT00825422Phase 31 country
- Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Cancer Pain on Long Term Opioid TherapyCompletedNCT04902547Not applicable1 country
- Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan Dose Response Clinical TrialCompletedNCT01435798Phase 21 country
- Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan/Lidocaine Combination Clinical TrialCompletedNCT02218203Phase 21 country
- Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and MethadoneCompletedNCT01594047Not applicable1 country
- Hyperalgesia and PainCompletedNCT01581450Phase 11 country
- Repeated Cannabis Administration on Experimental Pain and Abuse LiabilityCompletedNCT04576507Phase 21 country
- Mechanisms of Pain Hypersensitivity in a Human Skin Inflammation ModelCompletedNCT07092215Early Phase 11 country
- A Research Study to Examine Cutaneous Allodynia and Cluster HeadacheCompletedNCT003298361 country
- Preventing Pain After Heart SurgeryCompletedNCT01480765Phase 41 country
- Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass GraftingCompletedNCT03450161Phase 41 country
- Pain Medicine for Wound Care ProceduresCompletedNCT00701909Phase 32 countries
- Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn InjuryCompletedNCT02684669Phase 21 country
- Effect of High-dose Naloxone Following Third Molar ExtractionCompletedNCT02976337Phase 21 country
- Effect of High-dose Naloxone Infusion on Pain and Hyperalgesia in Patients Following Groin-Hernia Repair.CompletedNCT01992146Phase 21 country
- Electrical Intra-cutaneous Half-sine Stimulation for Optimized Preferential C-fiber ActivationCompletedNCT05440266Not applicable1 country
- The Effect of Palmitylethanolamide on Central and Peripheral Sensitization After Heat-induced HyperalgesiaCompletedNCT04662827Not applicable1 country
- The Effect of Remimazolam on Opioid Induced HyperalgesiaCompletedNCT05866315Not applicable1 country
- A Study of Sativex® for Pain Relief of Peripheral Neuropathic Pain, Associated With AllodyniaCompletedNCT00710554Phase 31 country
- A Study of Sativex® for Relief of Peripheral Neuropathic Pain Associated With Allodynia.CompletedNCT00711880Phase 31 country
- Effect of Daytime Variation on Postoperative Hyperalgesia Induced by OpioidsCompletedNCT052346971 country
- GentleCath Air (Urinary Self-catheterization) - Pain in Female Patients With Neurological Vesico-sphincter DisordersWithdrawnNCT04847609
- Evaluation of the Antihyperalgesic Effect of Tapentadol in Two Human Experimental ModelsTerminatedNCT01615510Phase 11 country
- Reducing Nocebo Effects on Pressure PainCompletedNCT05284383Not applicable1 country
- ERECTOR SPINE PLANE BLOCK VERSUS LOCAL INFILTRATION ANAESTHESIA FOR TRANSFORAMINAL PERCUTANEOUS ENDOSCOPIC DISCECTOMYCompletedNCT05483647Not applicable1 country
- Comparison of Postoperative Nociception Between NOL-guided and Standard Intraoperative Analgesia Based on FentanylCompletedNCT03858621Not applicable1 country
- Trial Investigating the Characteristics of Knismesis - a Lever to Explore Allodynia in Neuropathic PainStatus unknownNCT04621747Not applicable1 country
- Central Sensitisation and Postoperative PainStatus unknownNCT04220697Not applicable1 country
- Intraoperative S-ketamine to Prevent Postoperative Hyperalgesia in Patients Undergoing Video-assisted Thoracic SurgeryStatus unknownNCT05016128Not applicable1 country
- Comparison of Remifentanil-induced Postoperative Hyperalgesia Between Patients From Plain Area and Plateau AreaStatus unknownNCT050280491 country
- Effect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative HyperalgesiaCompletedNCT03096730Not applicable1 country
- Gabapentin Pretreatment for Staged Bilateral Cataract OperationsCompletedNCT03826615Not applicable1 country