Hyperalgesia: all 154 studies

Page 1 of 2. Open to participants first (14), then studies with results posted, then the rest; newest registration first within each.

• Photobiomodulation After Nonsurgical Root Canal TreatmentNot yet recruitingNCT07886723Not applicable
• Perioperative Quantitative Sensory Testing and Incision Pain Mapping in Thoracic SurgeryNot yet recruitingNCT07653932
• FROST-STERN Trial: A Trial of Intraoperative Cryoablation for Post Operative Pain Management After Full SternotomyNot yet recruitingNCT07637370Not applicable
• Open-Label Safety Study of AXS-14 in Subjects With FibromyalgiaEnrolling by invitationNCT07637162Phase 3
• Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research DesignRecruitingNCT07398417Phase 3
• Music Therapy During Hypothermia in the NICUNot yet recruitingNCT06951269Not applicable
• Survey for Parental Perception of Procedural Analgosedation in Pediatric Age.RecruitingNCT06794879
• Investigation on the Status Quo of Hyperalgesia in Patients After Thoracoscopic Operation and Study on the Effect of Intraoperative InterventionRecruitingNCT06790914Not applicable
• Response Profiles to High-concentration Capsaicin Desensitization in Patients with Peripheral Neuropathic Pain with or Without Allodynia: a Regional Multicenter Prospective CohortRecruitingNCT05817591
• Electroacupuncture Pain Treatment, Mechanical Hyperalgesia, Quality of Life & Expression of Mu+ B Cells in FibromyalgiaRecruitingNCT05357157
• Safety and Efficacy Evaluation of S (+) - Ketamine in ChildrenEnrolling by invitationNCT04834427Phase 4
• Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal DeformationsRecruitingNCT04697498Not applicable
• Neurosensorial Disorder and Pain in Oral Cavity and Oropharynx Cancer Traited Patients (OCAPA)RecruitingNCT04673981Not applicable
• Post-operative Analgesic Effect of Oral NefopamRecruitingNCT04576078Phase 2
• Repeated Cannabis Administration on Experimental Pain and Abuse LiabilityCompletedNCT04576507Phase 2Results posted
• Effect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative HyperalgesiaCompletedNCT03096730Not applicableResults posted
• Effect of Ultra-low Dose Naloxone on Remifentanil-Induced HyperalgesiaTerminatedNCT03066739Phase 2Results posted
• The Efficacy of MK-8291 in Participants With Post-herpetic Neuralgia (PHN) With Allodynia (MK-8291-012)CompletedNCT02336555Phase 1Results posted
• Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan/Lidocaine Combination Clinical TrialCompletedNCT02218203Phase 2Results posted
• Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in PatientsCompletedNCT02043366Not applicableResults posted
• Mechanisms of Sleep Disruption HyperalgesiaCompletedNCT01794689Not applicableResults posted
• Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and MethadoneCompletedNCT01594047Not applicableResults posted
• IV Acetaminophen as an Adjunct Analgesic in Cardiac SurgeryCompletedNCT01544062Phase 4Results posted
• Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan Dose Response Clinical TrialCompletedNCT01435798Phase 2Results posted
• Low Dose Ketamine Study on Opioid Tolerance and HyperalgesiaCompletedNCT01325493Phase 4Results posted
• Evaluation of the Effect of Ketamine on Remifentanil-induced HyperalgesiaCompletedNCT01301079Phase 3Results posted
• Study on the Effect of a Beta Blocker on Increased Sensitivity to Pain in Humans Caused by OpioidsCompletedNCT01222091Phase 2Results posted
• Hyperalgesia in Methadone-Maintained Patients: Can it be Treated?CompletedNCT01210079Phase 2Results posted
• Transversus Abdominis Plane (TAP) Block for Cesarean SectionCompletedNCT01015807Not applicableResults posted
• Study on the Development of Opioid Induced Hyperalgesia (OIH) After Exposure to AlfentanilCompletedNCT00991809Not applicableResults posted
• Effect of Ketamine on Opioid-Induced HyperalgesiaCompletedNCT00833755Not applicableResults posted
• Subcutaneous Botulinum Toxin for Cutaneous Allodynia - Enriched Responder TrialTerminatedNCT00822926Not applicableResults posted
• Subcutaneous Botulinum Toxin for Cutaneous AllodyniaCompletedNCT00725322Not applicableResults posted
• A Study of Sativex® for Relief of Peripheral Neuropathic Pain Associated With Allodynia.CompletedNCT00711880Phase 3Results posted
• A Study of Sativex® for Pain Relief of Peripheral Neuropathic Pain, Associated With AllodyniaCompletedNCT00710554Phase 3Results posted
• Pain Medicine for Wound Care ProceduresCompletedNCT00701909Phase 3Results posted
• The Effect of Intravenous Lidocaine on AllodyniaCompletedNCT00659633Not applicableResults posted
• Prevalence of Phonophobia and Cutaneous Allodynia in Episodic MigraineursCompletedNCT00386880Results posted
• A Research Study to Examine Cutaneous Allodynia and Cluster HeadacheCompletedNCT00329836Results posted
• Session-Order Sensitivity of TS and OA in a Capsaicin Crossover ModelCompletedNCT07625475Not applicable
• Mechanisms of Pain Hypersensitivity in a Human Skin Inflammation ModelCompletedNCT07092215Early Phase 1
• The Effect of Remimazolam on Opioid Induced HyperalgesiaCompletedNCT05866315Not applicable
• STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic PancreatitisActive, not recruitingNCT05603702Phase 1
• ERECTOR SPINE PLANE BLOCK VERSUS LOCAL INFILTRATION ANAESTHESIA FOR TRANSFORAMINAL PERCUTANEOUS ENDOSCOPIC DISCECTOMYCompletedNCT05483647Not applicable
• Electrical Intra-cutaneous Half-sine Stimulation for Optimized Preferential C-fiber ActivationCompletedNCT05440266Not applicable
• Reducing Nocebo Effects on Pressure PainCompletedNCT05284383Not applicable
• Effect of Daytime Variation on Postoperative Hyperalgesia Induced by OpioidsCompletedNCT05234697
• Comparison of Remifentanil-induced Postoperative Hyperalgesia Between Patients From Plain Area and Plateau AreaStatus unknownNCT05028049
• Intraoperative S-ketamine to Prevent Postoperative Hyperalgesia in Patients Undergoing Video-assisted Thoracic SurgeryStatus unknownNCT05016128Not applicable
• Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Cancer Pain on Long Term Opioid TherapyCompletedNCT04902547Not applicable
• GentleCath Air (Urinary Self-catheterization) - Pain in Female Patients With Neurological Vesico-sphincter DisordersWithdrawnNCT04847609
• The Effect of Palmitylethanolamide on Central and Peripheral Sensitization After Heat-induced HyperalgesiaCompletedNCT04662827Not applicable
• Trial Investigating the Characteristics of Knismesis - a Lever to Explore Allodynia in Neuropathic PainStatus unknownNCT04621747Not applicable
• Impact of Repeatedly-Administered THC-cannabis on Experimental Pain and Abuse Liability in HumansSuspendedNCT04596644Phase 2
• Validation of a Questionnaire for Allodynia in Migraine.Status unknownNCT04580641
• Drip-infusion of Remifentanil for RIHCompletedNCT04387097
• Central Sensitisation and Postoperative PainStatus unknownNCT04220697Not applicable
• Electrophysiological Correlates of Nocebo Effects on PainCompletedNCT04199858Not applicable
• Pain-related Fear as a Facilitator of Nocebo HyperalgesiaCompletedNCT04197154Not applicable
• Pain Response to Cannabidiol in Opioid-induced Hyperalgesia, Acute Nociceptive Pain and Allodynia By Using a Model Mimicking Acute Pain in Healthy AdultsCompletedNCT04059978Not applicable
• Pain Response to Cannabidiol in Induced Acute Nociceptive Pain, Allodynia and Hyperalgesia By Using a Model Mimicking Acute Pain in Healthy AdultsCompletedNCT03985995Not applicable
• Reliability of Measuring the Area and Intensity of Secondary Hyperalgesia Induced by High Frequency StimulationCompletedNCT03966508Not applicable
• Effect of Cannabinoid (THC / CBD 50%) on Hyperalgesia in Patients With Deep EndometriosisStatus unknownNCT03875261Phase 2
• Comparison of Postoperative Nociception Between NOL-guided and Standard Intraoperative Analgesia Based on FentanylCompletedNCT03858621Not applicable
• Exercise-induced Ischemia and the Influence of Pain Modulation in a Nerve Growth Factor (NGF) ModelStatus unknownNCT03844243Early Phase 1
• Gabapentin Pretreatment for Staged Bilateral Cataract OperationsCompletedNCT03826615Not applicable
• The Role of Learning in Nocebo HyperalgesiaCompletedNCT03793790Not applicable
• Can DFN-15 Terminate Migraine With Allodynia?CompletedNCT03472378Phase 2
• Interaction Between NGF and Acute Exercise-induced IschemiaCompletedNCT03470038Early Phase 1
• Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass GraftingCompletedNCT03450161Phase 4
• Cortical Neuroplasticity by Muscle Pain of Pain-induced PlasticityCompletedNCT03354624Not applicable
• Prevention of Hyperalgesia With Epidural MorphineStatus unknownNCT03225690Phase 4
• Spread of Muscle Hyperalgesia and Pain in a Low Dose NGF-induced Pain ModelCompletedNCT03217942Early Phase 1
• The Relationship Between Saliva β-endorphins Levels, Cold Pressor Test and Perception of Pain in Oral Surgery ProceduresStatus unknownNCT03164161Not applicable
• The Effects of Opioid Taper on Opioid-Induced HyperalgesiaTerminatedNCT03063905
• Administration of Acetazolamide to Prevent Remifentanil Induced HyperalgesiaCompletedNCT02992938Phase 4
• Effect of High-dose Naloxone Following Third Molar ExtractionCompletedNCT02976337Phase 2
• DNA Methylation and Perioperative Pain TreatmentCompletedNCT02938455
• Opioid Induced Hyperalgesia (OIH) Modulation With PropranololStatus unknownNCT02934763Phase 4
• An fMRI Study in Healthy Volunteers to Investigate the Effects of ABX-1431 on Experimental Hyperalgesia and Its Neural CorrelatesCompletedNCT02929264Phase 1
• A Trial of Lidocaine Patch for Lower Limb Amputation PainWithdrawnNCT02696720Phase 2
• Pilot Study to Compare Topical Voriconazole to Placebo as a Pain Reducing AgentWithdrawnNCT02689713Phase 2
• Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn InjuryCompletedNCT02684669Phase 2
• L-menthol as a Topical Counter-irritant to TRPA1-induced Neurogenic Inflammation and PainCompletedNCT02653703Not applicable
• Dextromethorphan Effect on Central Sensitization to Pain in Healthy VolunteersCompletedNCT02596360Phase 1
• Evaluation of the Efficacy of Somatosensory Rehabilitation of Pain by Vibrotactile Stimulation on Static Mechanical AllodyniaCompletedNCT02571010Not applicable
• Is the Volume of the Caudate Nuclei Associated With Area of Secondary Hyperalgesia?CompletedNCT02567318Not applicable
• Association Between Heat Pain Detection Threshold and Area of Secondary HyperalgesiaCompletedNCT02527395Not applicable
• The Effect of Hyperbaric Oxygen Therapy on Inflammatory Parameters Induced by a Heat Injury ModelCompletedNCT02397343Phase 2
• Use of Intrathecal Fentanyl and Development of Hyperalgesia in Patients Undergoing Elective CesareanStatus unknownNCT02387060Phase 4
• A Randomized, Double-Blind Study of Placebo vs. Ketamine For Use During Dressing Changes in Critically Ill Burn PatientsWithdrawnNCT02336308Phase 4
• Delineating Areas of Secondary Hyperalgesia: Influence of the Assessment MethodCompletedNCT02286037
• Preoperative Intraarticular Injection of Methylprednisolone in Patients Scheduled for Total Knee-arthroplastyCompletedNCT02253966Phase 2
• Can Fentanyl Lead to Opioid-induced Hyperalgesia in Healthy Volunteers?CompletedNCT02252458Not applicable
• Prevention of Remifentanil-induced Postoperative Hyperalgesia With Intravenous IbuprofenCompletedNCT02243254Not applicable
• Characterization of Secondary Hyperalgesia in Healthy VolunteersCompletedNCT02166164Not applicable
• Cortical Representation of Hyperalgesia Induced by Nerve Growth FactorCompletedNCT02159170Not applicable
• Effect of Gabapentin on Pain of the Second Cataract SurgeryStatus unknownNCT02127853Phase 4
• Hyperalgesia and NMDA Receptor AntagonistStatus unknownNCT02087202Not applicable
• Somatosensory Assessment and Rehabilitation of Allodynia (SARA)CompletedNCT02070367Not applicable

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