Glaucoma clinical trials
The registry lists 1,419 studies for Glaucoma across more than 10 countries. 223 are recruiting or about to start. 986 of them are mainly about Glaucoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 5 narrower conditions too, such as Glaucoma, Open-Angle: 2,182 studies, 314 open.
ClinicalTrials.gov finds 2,256 studies for Glaucoma. How that becomes 1,419 here
This page counts the studies the registry files under Glaucoma, and those it files under no condition that list Glaucomathemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 2,256Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −761Filed under a narrower condition, counted on its own pageGlaucoma, Open-Angle 627 · Glaucoma, Angle-Closure 51 · Hydrophthalmos 28 · Glaucoma, Neovascular 25 · Low Tension Glaucoma 22
- −24List Glaucoma as a condition, but the registry did not file them under itMost often written as “Glaucoma, Suspect” (4), “Pseudoexfoliation Glaucoma” (4), and “Primary Glaucoma” (3). The registry filed them under other conditions only, most often Ocular Hypertension (9) and Cataract (5).
- −52Match it another way49 name it in the title, 2 in a keyword, and 1 by a synonym or other text the search reads.
- 1,419The count on this page55 of them list Glaucoma in their own words; the registry filed them under no condition.
Get an email when these change. Save the Glaucoma studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
Alcon Research (77) · Wills Eye (38) · Allergan (33) · Glaukos Corporation (22) · University of Zurich (19) · Medical University of Vienna (17) · Sun Yat-sen University (16) · Stanford University (16)
What is being tested here
Drugs under test in Glaucoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Niacinamide | 3 | 1 | 5 |
| Latanoprost | 2 | 10 | 45 |
| Netarsudil | 2 | 5 | 11 |
| Insulin | 2 | 0 | 3 |
| Brimonidine | 1 | 3 | 23 |
| Mitomycin | 1 | 3 | 11 |
| Cytidine Diphosphate Choline | 1 | 2 | 7 |
| Aflibercept | 1 | 1 | 3 |
| Pilocarpine | 1 | 1 | 3 |
| Apraclonidine | 1 | 0 | 2 |
Drug classes tested here Angiogenesis inhibitors 1 open · Beta blockers 40 · Corticosteroids 17 · Diuretics 5 · NSAIDs 5
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jun 2027Clarifying the Optimal Application of SLT Therapy Trial · Phase 3 · University of Pittsburgh
- Jul 2027Nicotinamide Supplementation in Glaucoma · Phase 3 · Singapore Eye Research Institute
- Nov 2026Long-Term Clinical Results of Ab-Interno Trabeculotomy in Glaucoma Management · Wuerzburg University Hospital
- Nov 2026Glaucoma Related Quality of Life · Marc Toeteberg-Harms
- Dec 2026Electrical Stimulation for the Treatment of Optic Neuropathies · Stanford University
- Dec 2026Electrical Stimulation for the Treatment of Glaucoma · Stanford University
- Dec 2026A Real-World Evidence Study of Goniotomy With the C-REX™ Instrument in Patients With Primary Open Angle Glaucoma · Iantrek, Inc.
- Dec 2026Rocklatan Retinal Perfusion OCT Study · Oregon Health and Science University
- Dec 2026A Study Evaluating the Safety and Efficacy of MINIject S+ in Subjects With Open Angle Glaucoma · iSTAR Medical
- Dec 2026Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial · University of Pennsylvania
Who these studies take
Of the 156 Glaucoma studies recruiting now, 114 (73%) set no upper age limit and 9 (6%) stop at 75 or younger. 13 (8%) take children under 18. 1 (1%) are for women only and 0 (0%) for men only; 45 (29%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 13 (8%) | 13 (8%) |
| 18 | 111 (71%) | 110 (71%) |
| 30 | 126 (81%) | 125 (80%) |
| 40 | 140 (90%) | 139 (89%) |
| 50 | 149 (96%) | 148 (95%) |
| 65 | 154 (99%) | 153 (98%) |
| 75 | 152 (97%) | 151 (97%) |
| 85 | 135 (87%) | 134 (86%) |
Across all 1,419 studies, recruiting or not: 10% stop at 75 or younger and 6% at 65; 10% take children; <1% are for women only and 1% for men only; 26% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Glaucoma studies take
Of 44 phase 4 interventional studies under Glaucoma, half reached primary completion within 34 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 8 mo3–23 · 18 studies | — | — |
| Phase 2 | 11 mo6–22 · 32 studies | 7 mo6–11 · 23 studies | — |
| Phase 3 | 20 mo12–43 · 33 studies | 17 mo11–26 · 26 studies | — |
| Phase 4 | 34 mo11–66 · 44 studies | — | 34 mo12–45 · 32 studies |
| Interventional, no phase | 30 mo12–53 · 287 studies | 22 mo8–46 · 58 studies | 31 mo12–55 · 229 studies |
| Observational | 31 mo12–208 · 134 studies | — | 47 mo12–208 · 110 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting1
- Effect of Late Ripcord Removal From Glaucoma Drainage DeviceNov 9, 2026NCT07803536
Newly registered6
- AI-Assisted vs Conventional Teleglaucoma ReferralNov 5, 2026NCT07917741
- A Phase 2a Study Comparing the Efficacy, Safety and Tolerability of Pregabalin Eye Drops Comparing With Timolol Eye Drops in Adults With Glaucoma or High Eye Pressure.Nov 3, 2026NCT07913074
- Effects of Balance Training in Individuals With GlaucomaNov 2, 2026NCT07910955
- PAUL® Glaucoma Implant Safety and Effectiveness StudyOct 30, 2026NCT07907055
- VGFTe-(HD)-OD-2566: Adjunctive Aflibercept Ahmed Glaucoma Valve (AAA) StudyOct 23, 2026NCT07891182
Show 1 moreShow fewer
- Iopidine to Decrease Intraocular Pressure Rise After InjectionsOct 23, 2026NCT07891910
Studies
Recruiting first, then most recently updated. Showing 50 of 1,419. Browse all 1,419 → or search them.
- Effect of Late Ripcord Removal From Glaucoma Drainage DeviceRecruitingNCT07803536Not applicable1 country
- Implementing AI-based Glaucoma Screening Within Federally Qualified Health CentersRecruitingNCT06629649Not applicable1 country
- AI-Assisted vs Conventional Teleglaucoma ReferralNot yet recruitingNCT07917741Not applicable
- A Phase 2a Study Comparing the Efficacy, Safety and Tolerability of Pregabalin Eye Drops Comparing With Timolol Eye Drops in Adults With Glaucoma or High Eye Pressure.RecruitingNCT07913074Phase 21 country
- Automated Applanation Tonometry - UpdatedRecruitingNCT07298356Not applicable1 country
- Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision ImpairmentRecruitingNCT07341763Not applicable1 country
- Effects of Balance Training in Individuals With GlaucomaRecruitingNCT07910955Not applicable1 country
- PAUL® Glaucoma Implant Safety and Effectiveness StudyNot yet recruitingNCT07907055Not applicable
- Glaucoma Drop Aids Part 2Not yet recruitingNCT06806332Not applicable1 country
- Adaptive Optics OCT Evaluation of Rhopressa's Effects on the Retinal Ganglion Cells in Glaucoma PatientsRecruitingNCT07847073Phase 41 country
- VGFTe-(HD)-OD-2566: Adjunctive Aflibercept Ahmed Glaucoma Valve (AAA) StudyNot yet recruitingNCT07891182Phase 21 country
- Inflammatory Mediators of Glaucoma After Corneal Transplantation (AH-Tears)RecruitingNCT04339907Not applicable1 country
- Iopidine to Decrease Intraocular Pressure Rise After InjectionsNot yet recruitingNCT07891910Phase 41 country
- Timing of Glaucoma Drainage Device With Boston KeratoprosthesisRecruitingNCT02084745Not applicable1 country
- A Study About the Safety of ASP2767 and Whether it Helps People With Glaucoma-Related Optic Nerve DamageRecruitingNCT07770685Phase 1/21 country
- A Study Evaluating the Safety and Efficacy of MINIject S+ in Subjects With Open Angle GlaucomaRecruitingNCT07009236Not applicable2 countries
- Topical Insulin for GlaucomaRecruitingNCT05206877Phase 11 country
- Glaucoma Screening to Enhance At-Risk Californians' HealthRecruitingNCT06854198Not applicable1 country
- Topical Insulin for Glaucoma (TING2)Enrolling by invitationNCT07619482Phase 1/21 country
- The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma PatientsNot yet recruitingNCT04007276Phase 41 country
- Trabeculectomy Versus MicroShunt Implantation in Glaucoma Surgery (TIGER)Not yet recruitingNCT07869108Not applicable1 country
- Hyperbaric Oxygen Therapy for Optic NeuropathiesRecruitingNCT06128720Not applicable1 country
- Electrical Stimulation for Vision Neuroenhancement in GlaucomaRecruitingNCT06685211Not applicable1 country
- Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle GlaucomaRecruitingNCT07220876Not applicable2 countries
- Comparative Study of the Tomey FT-1000, and Goldmann Applanation Tonometer (GAT)RecruitingNCT078042771 country
- Efficacy and Safety of a Releasable Intraluminal Suture Technique to Reduce Hypotony Following Glaucoma Surgery Using the Preserflo DeviceRecruitingNCT07531199Not applicable1 country
- iDose TR Administration in an Office-Based Surgery SettingRecruitingNCT078166921 country
- Efficacy and Safety of the ELIOS Laser in Combined Cataract and Glaucoma SurgeryRecruitingNCT06760169Not applicable1 country
- Efficacy and Safety of Tran Cannula in Combined Pseudoexfoliative Glaucoma and Cataract Surgery Compared With Augmented Ocular IrrigationRecruitingNCT06979752Not applicable1 country
- Switching From Preserved Glaucoma Therapy to Preservative-Free ZOLYMBUSNot yet recruitingNCT07845357Phase 4
- Ocular Surface Disease in Glaucoma Patients on Long-Term TherapyNot yet recruitingNCT07841912
- Phase 2 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral ImplantRecruitingNCT07075718Phase 21 country
- Visual Function and Exercise in Glaucoma PatientsNot yet recruitingNCT078242321 country
- Dresden Glaucoma and Treatment Study (DGTS)RecruitingNCT029592421 country
- The Effect of Topical Rho-kinase Inhibitors on Corneas of Patients With Fuchs Endothelial Corneal DystrophyEnrolling by invitationNCT069695861 country
- Functional and Structural Imaging for GlaucomaRecruitingNCT019572671 country
- Glaucoma Screening to Enhance At-Risk Californians' Health - Survey Response IncentivesRecruitingNCT07755748Not applicable1 country
- GlaukomAI: Clinical Validation of an AI System for Early Glaucoma ScreeningNot yet recruitingNCT07668193Not applicable
- Impact of Home Intraocular Pressure Telemonitoring on Intraocular Pressure Control and Glaucoma ProgressionRecruitingNCT05940623Not applicable1 country
- Evaluation of Different Perimetric Grids to Detect Central Visual Field Defect in Glaucoma Patients With Reduce Ganglion Cell Layer Thickness Measured by Spectral Domain OCT.RecruitingNCT062276111 country
- Magnetic Resonance Imaging of Cerebral Connectivity and Volume in Neurodegeneration and GlaucomaRecruitingNCT07802769Not applicable1 country
- Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General PracticeRecruitingNCT07015034Not applicable1 country
- Eye Patient Adherence and Compliance StudyNot yet recruitingNCT07793474Not applicable1 country
- The Glaucoma and Retinopathy Screening StudyRecruitingNCT06882356Not applicable1 country
- Three Year Outcomes of Combined Hydrus Microstent With iTrack CanaloplastyEnrolling by invitationNCT070739371 country
- Know Your Pressures NYCNot yet recruitingNCT05992415Not applicable1 country
- Long-Term Clinical Results of Ab-Interno Trabeculotomy in Glaucoma ManagementRecruitingNCT077809161 country
- Smart Soft Contact Lenses for Monitoring GlaucomaEnrolling by invitationNCT07224542Not applicable1 country
- Behavioural Test for Early GlaucomaNot yet recruitingNCT07775898
- Impact of Meditation on Reducing Stress in Glaucoma Patients: An Electronic Feasibility StudyNot yet recruitingNCT07769463Not applicable