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RecruitingNCT02959242Updated Sep 16, 2026

Dresden Glaucoma and Treatment Study (DGTS)

An observational study in Glaucoma, Glaucoma, Open-Angle and Glaucoma, Angle-Closure, sponsored by Technische Universität Dresden. Recruiting at 1 site in Germany. Per ClinicalTrials.gov, last updated 2026-09-16.

Sponsored by Technische Universität Dresden · Observational

From the registry’s dates

  • Started Jan 2006; still recruiting 20 years 10 months later.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
10,000
Sex
All
01

Study summary

To assure the quality of follow-up and treatment, data of glaucoma patients are stored and evaluated after anonymisation.

Read the detailed description

The aim of the study is to evaluate the quality of follow-up and treatment by means of consecutive data collection and anonymised analysis of all glaucoma patients of a tertiary university hospital glaucoma service.

Parameters being analyzed are:

Age, sex, refraction, family history, known duration of glaucoma, highest intraocular pressure before treatment, systemic and topical medication, previous ocular surgery.

24h Goldmann-applanation tonometry, biomicroscopy, gonioscopy, Heidelberg Retinal Tomograph (HRT), glaucoma diagnosis with Scanning-Laser-Polarimetry (GDx), optical coherence tomography (OCT), Pentacam, Ocular Response Analyzer (ORA), Corvis ST (Corneal Visualization with the Scheimpflug Technology), perimetry

02

Conditions studied

  • Glaucoma
  • Glaucoma, Open-Angle
  • Glaucoma, Angle-Closure
  • Glaucoma, Low Tension

Keywords

  • Follow-up intervals
  • Treatment Efficiency
  • Laser Therapy
  • Glaucoma Surgery
  • Minimal Invasive Glaucoma Surgery (MIGS)
03

In context

Glaucoma

1,419 studies on the registry are indexed under Glaucoma; 223 are open to participants now.

This study's planned enrollment of 10,000 is above the median of 101 across 385 observational studies indexed under Glaucoma.

Browse Glaucoma studies →

Lead sponsor

Technische Universität Dresden is the lead sponsor of 247 studies on the registry; 46 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Glaucoma patients attending a tertiary University Hospital glaucoma Service.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • manifest glaucoma, ocular Hypertension, glaucoma suspect

Exclusion criteria

Exclusion Criteria:

  • under 18 years of age, corneal diseases
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
10,000 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Follow-up intervals

    To find the best follow-up intervals for glaucoma patients.

    Time frame: 20 years

Secondary outcomes

  1. Assessment of treatment quality

    What is the best treatment option for the individual patient?

    Time frame: 20 years

  2. Assessment of intraocular pressure-lowering efficacy and number of participants with treatment-related adverse events as assessed by CTCAE v4.0 of glaucoma laser therapy

    Diurnal intraocular pressure, best corrected visual acuity, visual fields

    Time frame: 20 years

  3. Assessment of intraocular pressure-lowering efficacy and number of participants with treatment-related adverse events as assessed by CTCAE v4.0 of glaucoma laser therapy of glaucoma surgery

    Diurnal intraocular pressure, best corrected visual acuity, visual fields

    Time frame: 20 years

07

Study locations

1 of 1 sites recruiting
08

References and documents

Publications

  • Pillunat KR, Herber R, Jamke M, Jasper CS, Haase MA, Manseck AS, Pillunat LE. Early Results of Preserflo MicroShunt for Primary Open Angle Glaucoma in White Patients. J Glaucoma. 2025 Feb 1;34(2):103-113. doi: 10.1097/IJG.0000000000002509. Epub 2024 Oct 11. PubMed 39401481 ↗
  • Jamke M, Herber R, Haase MA, Jasper CS, Pillunat LE, Pillunat KR. PRESERFLO MicroShunt versus trabeculectomy: 1-year results on efficacy and safety. Graefes Arch Clin Exp Ophthalmol. 2023 Oct;261(10):2901-2915. doi: 10.1007/s00417-023-06075-4. Epub 2023 May 3. PubMed 37133501 ↗
  • Pillunat KR, Kocket GA, Herber R, Jasper CS, Lenk J, Pillunat LE. Efficacy of selective laser trabeculoplasty on lowering intraocular pressure fluctuations and nocturnal peak intraocular pressure in treated primary open-angle glaucoma patients. Graefes Arch Clin Exp Ophthalmol. 2023 Jul;261(7):1979-1985. doi: 10.1007/s00417-022-05897-y. Epub 2022 Nov 23. PubMed 36418515 ↗

Individual participant data

Plan to share: No — Individual participant data are only shared between researchers of our Institute.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 16, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02959242
Responsible party
Dr. Karin Pillunat (Dr. med., Technische Universität Dresden) — Principal investigator
First posted
Nov 9, 2016
Start date
Jan 2006
Primary completion
Dec 2032 (estimated)
Completion
Dec 2032 (estimated)
Last update
Sep 16, 2026

Study contacts

Karin R Pillunat, MD
Contact
karin.pillunat@uniklinikum-dresden.de
+49 351 458 3274
Lutz E Pillunat, MD, PhD
Contact
lutze.pillunat@uniklinikum-dresden.de
+49 351 458 3381
Lutz E Pillunat, MD, PhD
study director · Medical faculty of the Technical University of Dresden, Germany

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

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