Glaucoma, Open-Angle clinical trials
The registry lists 928 studies for Glaucoma, Open-Angle across more than 10 countries. 121 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-23.
Status
- Completed
- 581
- Status unknown
- 91
- Recruiting
- 85
- Terminated
- 62
- Active, not recruiting
- 40
- Not yet recruiting
- 28
Phase
- Phase 2
- 151
- Phase 3
- 149
- Phase 4
- 123
- Phase 1
- 60
- Early Phase 1
- 3
Where
- United States
- 350
- Germany
- 61
- Spain
- 48
- Canada
- 44
- China
- 39
- Italy
- 38
Who runs them
Alcon Research (95) · Allergan (48) · Glaukos Corporation (46) · Aerie Pharmaceuticals (18) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (16) · Medical University of Vienna (14) · Santen Pharmaceutical Co., Ltd. (13) · Wills Eye (13)
Studies
Recruiting first, then most recently updated. Showing 50 of 928 — search for more.
- A Study to Evaluate Efficacy and Safety of YSBP Compared to Lumigan in Patients With Glaucoma or Ocular HypertensionRecruitingNCT07661329Phase 32 countries
- Hydrus® Microstent New Enrollment Post-Approval StudyRecruitingNCT04553523Not applicable1 country
- A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With GlaucomaRecruitingNCT06822738Phase 31 country
- Phase 2 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral ImplantRecruitingNCT07075718Phase 21 country
- Combined Phacoemulsification-Goniotomy in Primary Open-Angle and Primary Angle-Closure GlaucomaNot yet recruitingNCT07821827Not applicable
- Dresden Glaucoma and Treatment Study (DGTS)RecruitingNCT029592421 country
- Direct vs. Conventional SLT in Open-Angle Glaucoma: A RCTEnrolling by invitationNCT06925477Not applicable1 country
- iDose TR Administration in an Office-Based Surgery SettingRecruitingNCT078166921 country
- Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)Not yet recruitingNCT07808333Phase 21 country
- Impact of Home Intraocular Pressure Telemonitoring on Intraocular Pressure Control and Glaucoma ProgressionRecruitingNCT05940623Not applicable1 country
- Three Year Outcomes of Combined Hydrus Microstent With iTrack CanaloplastyEnrolling by invitationNCT070739371 country
- A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and DiseasesRecruitingNCT077808901 country
- A Phase II Trial of G01 Eye Drops for Glaucomatous Optic NeuropathyRecruitingNCT07777861Phase 21 country
- Caffeine Consumption in Glaucoma Patients and Healthy SubjectsRecruitingNCT03675412Not applicable1 country
- Testing a Reading Module to Improve Reading Skills and Quality of Life in Glaucoma PatientsNot yet recruitingNCT07741812Not applicable1 country
- A Study of Outcomes Following Bio-Reinforced Canaloplasty in Eyes With Open-Angle GlaucomaEnrolling by invitationNCT075201751 country
- 5-Year Postoperative Outcomes of Patients Who Completed the CREST StudyEnrolling by invitationNCT074803431 country
- Clinical Characteristics of Pigmentary Glaucoma and Efficacy Analysis of Ab-interno 120° TrabeculotomyRecruitingNCT077130561 country
- PRESERFLO™ MicroShunt XI Observational PMCF Study With no Control GroupRecruitingNCT072355928 countries
- PEI-GT Trial for Initial Treatment of Primary Open-Angle Glaucoma With CataractRecruitingNCT07700498Not applicable1 country
- REGN22530 for Adults With Primary Open Angle Glaucoma or Ocular HypertensionNot yet recruitingNCT07675824Phase 1/2
- [KJ-TFC-005] Phase 3 Study, Evaluate the Efficacy and Safety of TFC-003 in Patients With Primary Open-Angle Glaucoma or Ocular HypertensionRecruitingNCT07662759Phase 31 country
- Comparative Effectiveness and Safety of ELIOS in Patients With Open-Angle Glaucoma Undergoing Cataract SurgeryRecruitingNCT06246136Not applicable6 countries
- Comparison of Goniotomy Device Outcomes in Combined Phacoemulsification-goniotomy SurgeriesNot yet recruitingNCT07418853Not applicable1 country
- Travoprost Intraocular Implant + iStent InfiniteRecruitingNCT06066645Phase 41 country
- Topical Insulin for Glaucoma (TING2)Not yet recruitingNCT07619482Phase 1/21 country
- Efficacy and Safety of DNN.31.19.026 for Ocular Hypertension or Primary Open-Angle GlaucomaNot yet recruitingNCT07617532Phase 3
- Additive Efficacy of Physical Activity Program in Hypthyroidism Elder Females With Glaucoma and Fatty Liver IssuesRecruitingNCT07599241Not applicable1 country
- Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)RecruitingNCT07290244Phase 11 country
- Adaptive Optics Retinal ImagingRecruitingNCT05370287Not applicable1 country
- Direct vs Standard SLT for Glaucoma: A Noninferiority TrialRecruitingNCT07408154Not applicable1 country
- GVB-2001 Gene Therapy Via Intracameral Injection for the Treatment of Primary Open Angle GlaucomaRecruitingNCT06921317Phase 1/21 country
- 24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension PatientsRecruitingNCT07325240Phase 41 country
- DSLT for Reducing Medication in GlaucomaRecruitingNCT073908901 country
- A Trial of Hydrus Microstent Versus GoniotomyRecruitingNCT06289491Not applicable1 country
- Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral ImplantRecruitingNCT07495852Phase 31 country
- Preserflo MicroShunt Versus TrabeculectomyRecruitingNCT07496957Not applicable1 country
- Combined Non-Invasive Brain and Visual Stimulation for Vision ImprovementNot yet recruitingNCT07486323Not applicable1 country
- Personalized Mobile Reminders for Medication Adherence and Intraocular Pressure Control in Primary Open-Angle GlaucomaNot yet recruitingNCT07480577Not applicable
- Quality of Life After Glaucoma Surgery: Evaluating the Patient Perspective Across Surgical OptionsRecruitingNCT073032571 country
- Transcorneal Electrical Stimulation for the Treatment of Visual Field Defects in Patients With Open-Angle GlaucomaRecruitingNCT06682962Not applicable1 country
- Aqueous Humor and Ocular Tissue Analysis in Glaucoma and CataractRecruitingNCT07462000Not applicable1 country
- UBM Evaluation After Combined Deep Sclerectomy With Trabeculotomy in Primary Open Angle GlaucomaRecruitingNCT074544471 country
- Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication UseRecruitingNCT07217678Phase 41 country
- Glaucoma Respsosne to Lifestyle Corrections in Sleep ApneaRecruitingNCT07447011Not applicable1 country
- Comparison of Visual Outcomes and Patient Satisfaction in Mild to Moderate Glaucoma Patients Undergoing Cataract Surgery With EDOF Versus Monofocal IOLsNot yet recruitingNCT07436871Not applicable
- Clinical Trial to Evaluate the Safety and Effectiveness of a Canaloplasty Device in Subjects With Open-Angle GlaucomaRecruitingNCT05696561Not applicable3 countries
- Observational Trial of the Updated Inserter for the Travoprost Intracameral Implant 75mcgRecruitingNCT074009261 country
- The Acute Effect of Exercise Type And Timing on Ambulatory Blood Pressure and Intra-Ocular Pressure in Individuals With Glaucoma (The ACHIEVE-project).Not yet recruitingNCT07413614Not applicable1 country
- Clinical Study Evaluating the Safety and Performance of the MIST Device for Intraocular Pressure Reduction in Patients With Primary Open-Angle GlaucomaRecruitingNCT07358650Not applicable1 country