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Glaucoma, Open-Angle clinical trials

The registry lists 924 studies for Glaucoma, Open-Angle across more than 10 countries. 117 are recruiting or about to start. 865 of them are mainly about Glaucoma, Open-Angle (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Hydrophthalmos too: 960 studies, 119 open.

ClinicalTrials.gov finds 1,086 studies for Glaucoma, Open-Angle. How that becomes 922 here

This page counts the studies the registry files under Glaucoma, Open-Angle, and those it files under no condition that list Glaucoma, Open-Anglethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 1,086Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −36Filed under a narrower condition, counted on its own pageHydrophthalmos 36
  3. −11List Glaucoma, Open-Angle as a condition, but the registry did not file them under itMost often written as “Primary Open Angle Glaucoma of Both Eyes” (3), “Subjects With Primary Open-angle Glaucoma (POAG)” (1), and “Subject With Primary Open-angle Glaucoma (POAG)” (1). The registry filed them under other conditions only, most often Glaucoma (9) and Ocular Hypertension (3).
  4. −117Match it another way103 name it in the title, 3 in a keyword, and 11 by a synonym or other text the search reads.
  5. 922The count on this page4 of them list Glaucoma, Open-Angle in their own words; the registry filed them under no condition.

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Status

Completed
577
Status unknown
91
Recruiting
83
Terminated
66
Active, not recruiting
40
Withdrawn
28

Phase

Phase 3
146
Phase 2
143
Phase 4
135
Phase 1
58
Early Phase 1
3

Where

United States
348
Germany
64
Spain
47
Canada
41
China
38
Italy
35

Who runs them

Alcon Research (102) · Allergan (48) · Glaukos Corporation (43) · Aerie Pharmaceuticals (18) · Wills Eye (15) · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (15) · Santen Pharmaceutical Co., Ltd. (13) · Sensimed AG (12)

What is being tested here

Drugs under test in Glaucoma, Open-Angle studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Netarsudil3517
Travoprost21646
Bimatoprost2929
Bimatoprost Ophthalmic Solution215
Brimonidine1418
Ketorolac103
Cytidine Diphosphate Choline112
Niacinamide102
Semaglutide101
AMDX2011P101

Drug classes tested here Beta blockers 33 · Corticosteroids 4

Coming up

12phase 3 studies under way
52studies finish main data collection within a year5 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 83 Glaucoma, Open-Angle studies recruiting now, 64 (77%) set no upper age limit and 5 (6%) stop at 75 or younger. 5 (6%) take children under 18. 1 (1%) are for women only and 0 (0%) for men only; 11 (13%) take healthy volunteers.

Recruiting studies that take each age, of 83
AgeWomenMen
104 (5%)4 (5%)
1851 (61%)51 (61%)
3062 (75%)62 (75%)
4074 (89%)74 (89%)
5081 (98%)81 (98%)
6582 (99%)81 (98%)
7582 (99%)81 (98%)
8575 (90%)75 (90%)

Across all 924 studies, recruiting or not: 6% stop at 75 or younger and 2% at 65; 6% take children; <1% are for women only and <1% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Glaucoma, Open-Angle studies take

Of 49 phase 3 interventional studies under Glaucoma, Open-Angle, half reached primary completion within 25 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 115 mo7–23 · 17 studies——
Phase 211 mo7–18 · 41 studies11 mo6–16 · 38 studies—
Phase 325 mo12–39 · 49 studies25 mo12–39 · 47 studies—
Phase 420 mo14–37 · 45 studies——
Interventional, no phase35 mo19–61 · 170 studies33 mo19–64 · 70 studies35 mo16–57 · 100 studies
Observational25 mo12–… · 53 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Started recruiting1

Stopped1

Newly registered4

Studies

Recruiting first, then most recently updated. Showing 50 of 924. Browse all 924 → or search them.