ClinicalTrials.gg
RecruitingNCT06227611Updated Sep 3, 2026

Evaluation of Different Perimetric Grids to Detect Central Visual Field Defect in Glaucoma Patients With Reduce Ganglion Cell Layer Thickness Measured by Spectral Domain OCT.

An observational study in Glaucoma, sponsored by Fondazione G.B. Bietti, IRCCS. Recruiting at 2 sites in Italy. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-03.

Sponsored by Fondazione G.B. Bietti, IRCCS · Observational

From the registry’s dates

  • Started May 2021; still recruiting 5 years 6 months later.
Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
16
Ages
18 Years and older
Sex
All
01

Study summary

The aim of the study is to evaluate the agreement between three different grids in detecting central visual field defect in early glaucoma patients with reduced ganglion cell layer thickness.

02

Conditions studied

  • Glaucoma

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03

In context

Glaucoma

1,419 studies on the registry are indexed under Glaucoma; 223 are open to participants now.

This study's planned enrollment of 16 is below the median of 101 across 385 observational studies indexed under Glaucoma.

Browse Glaucoma studies →

Lead sponsor

Fondazione G.B. Bietti, IRCCS is the lead sponsor of 19 studies on the registry; 7 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

glaucoma patients referring to glaucoma clinic of IRCCS-Fondazione GB Bietti and University of Rome Tor Vergata.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • glaucoma patients with glaucomatous optic nerve head defect and reduced ganglion cell layer thickness

Exclusion criteria

Exclusion Criteria:

  • age\<18 years
  • unable to read, understand and sign the written
  • unable to perform visual field test
  • advanced glaucoma with C/D>0.7
  • other causes of optic neuropathies
  • retinal or macular diseases
  • lens or corneal opacities
  • spherical refractive defect >± 6D
  • cylindric refractive defect >± 3D
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
16 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. the agreement between 10-2 HFA and 24-2c HFA in detecting central visual field defect

    central visual field is defined by the presence of a cluster of three test locations with significantly reduced sensitivity in a hemifield fo the pattern deviation plot.

    Time frame: 12 month

Secondary outcomes

  1. the agreement between 24-2c HFA and G1 Octopus in detecting central visual field defect

    central visual field is defined by the presence of a cluster of three test locations with significantly reduced sensitivity in a hemifield fo the pattern deviation plot.

    Time frame: 12 month

07

Study locations

2 of 2 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 3, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06227611
Lead sponsor
Fondazione G.B. Bietti, IRCCS
Responsible party
Sponsor
First posted
Jan 29, 2024
Start date
May 4, 2021
Primary completion
May 4, 2022
Completion
May 4, 2029 (estimated)
Last update
Sep 3, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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No contact was published for this record. The registry link below has the sponsor’s details.

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