Low Tension Glaucoma clinical trials
The registry lists 65 studies for Low Tension Glaucoma across more than 10 countries. 10 are recruiting or about to start. 33 of them are mainly about Low Tension Glaucoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02.
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Who runs them
Universitaire Ziekenhuizen KU Leuven (7) · Wills Eye (3) · Technische Universität Dresden (3) · Qlaris Bio, Inc. (3) · Medical University of Vienna (2) · Augenabteilung Allgemeines Krankenhaus Linz (2) · Helsinki University Central Hospital (2) · The Catholic University of Korea (2)
What is being tested here
Drugs under test in Low Tension Glaucoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Timolol | 0 | 0 | 4 |
| Brimonidine | 0 | 0 | 3 |
| QLS-111 | 0 | 0 | 2 |
| Netarsudil | 0 | 0 | 2 |
| Bimatoprost | 0 | 0 | 2 |
| Foslevcromakalim | 0 | 0 | 1 |
| Brinzolamide | 0 | 0 | 1 |
| Sovesudil | 0 | 0 | 1 |
| Bimatoprost Ophthalmic Solution | 0 | 0 | 1 |
| Travoprost | 0 | 0 | 1 |
Drug classes tested here Beta blockers 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
Who these studies take
Of the 5 Low Tension Glaucoma studies recruiting now, 3 (60%) set no upper age limit and 0 (0%) stop at 75 or younger. 1 (20%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (20%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (20%) | 1 (20%) |
| 18 | 2 (40%) | 2 (40%) |
| 30 | 2 (40%) | 2 (40%) |
| 40 | 3 (60%) | 3 (60%) |
| 50 | 3 (60%) | 3 (60%) |
| 65 | 5 (100%) | 5 (100%) |
| 75 | 5 (100%) | 5 (100%) |
| 85 | 5 (100%) | 5 (100%) |
Across all 65 studies, recruiting or not: 9% stop at 75 or younger and 6% at 65; 8% take children; 0% are for women only and 0% for men only; 43% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 65. Browse all 65 → or search them.
- Topical Insulin for Glaucoma (TING2)Enrolling by invitationNCT07619482Phase 1/21 country
- Dresden Glaucoma and Treatment Study (DGTS)RecruitingNCT029592421 country
- Transcorneal Electrical Stimulation for the Treatment of Visual Field Defects in Patients With Open-Angle GlaucomaRecruitingNCT06682962Not applicable1 country
- DSLT in Normal Tension Glaucoma (NTG) Asian EyesNot yet recruitingNCT07300852Not applicable1 country
- Optic Nerve Head Evaluation Through Multimodal Blood Flow Analysis: a Prospective Observational, Multi-center StudyNot yet recruitingNCT07075887
- Obstructive Sleep Apnea as a Risk Factor for Normal Tension Glaucoma and a Crucial Step in Preventing BlindnessNot yet recruitingNCT060239271 country
- Investigation of Neurovascular Coupling in Glaucoma Patients and Healthy SubjectsRecruitingNCT03870230Not applicable1 country
- R&D of Non-invasive Innovative Intracranial Waves Monitoring System for Diagnostics and Treatment Monitoring of Patients with Normal Tension GlaucomaEnrolling by invitationNCT064434111 country
- Deep Sclerectomy Versus Trabeculectomy in Normal Tension GlaucomaRecruitingNCT05371977Not applicable1 country
- Endoscopic Cyclophotocoagulation in Normal Tension GlaucomaRecruitingNCT04651530Not applicable1 country
- Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel DilationCompletedNCT07354477Phase 21 country
- Direct Selective Laser Trabeculoplasty in Ethnic Chinese PopulationActive, not recruitingNCT05902871Not applicable2 countries
- Study of an Investigational Product, QLS-111, Provided as an Eyedrop, for Treatment of Normal Tension Glaucoma (NTG)CompletedNCT06030193Phase 21 country
- 24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP MonitoringCompletedNCT066896961 country
- Effect of Netarsudil vs Brimonidine in NTG Patients on LatanoprostCompletedNCT06449352Phase 41 country
- A Study to Evaluate Safety and Tolerability of QLS-101 in NTGCompletedNCT04857827Phase 21 country
- EVALUATION of CATS TONOMETER PRISM in LASIK SUBJECTSCompletedNCT062663511 country
- Trabecular Microbypass IStent in Patients with GlaucomaCompletedNCT06630546Not applicable1 country
- The Water Drinking Test in Glaucoma StudyCompletedNCT052830311 country
- IOP Lowering Effects of Topical Anesthetics Used Frequently in the Ophthalmology ClinicCompletedNCT012541491 country
- Reproducibility of Blood Flowmetry in Human Retina Using the Nidek Laser Speckle Flowgraphy LSFG-NAVI SystemCompletedNCT040149331 country
- Computer-aided Diagnosis of Ocular Diseases Based on Corneal BiomechanicsCompletedNCT044759001 country
- Study in Prostaglandin Associated Peri-orbitopathy Switching From Prostaglandin Monotherapy to Omidenepag IsopropylStatus unknownNCT05279716Phase 41 country
- Water Drinking Test Study and Disc Hemorrhages in Normal Tension GlaucomaStatus unknownNCT05075369Not applicable
- Intraocular Pressure Reduction Efficacy of Rhopressa and Lumigan in Normal Tension GlaucomaStatus unknownNCT04981886Phase 41 country
- Observational Study of the Long-term Effect of Latanoprost in Normal Tension GlaucomaCompletedNCT01209624
- Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography StudyCompletedNCT03323164Phase 41 country
- Measurement of the Effect of Gingko Biloba Extract on Ocular and Nailfold Blood-flow in NTGStatus unknownNCT03761992Not applicable1 country
- Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Tensor ImagingTerminatedNCT01864317Phase 21 country
- Isometric Exercise in NTGCompletedNCT03921372Not applicable1 country
- Advanced Glycation End Products as a Biomarker for Accelerated AgeingCompletedNCT028632241 country
- Assessing Ocular Hemodynamic Response to Surgical Intervention in GlaucomaTerminatedNCT028913171 country
- Additive Effect of Twice-daily Brinzolamide 1%/Brimonidine 0.2%Combination as an Adjunctive Therapy to Travoprost in Patients With Normal Tension GlaucomaCompletedNCT03150160Phase 41 country
- Evaluation of PHP-201 Ophthalmic Solution in Patients With Normal Tension GlaucomaCompletedNCT03106532Phase 21 country
- Efficacy and Safety of COMBIGAN® in Korean Patients With Primary Open Angle Glaucoma (POAG) and Normal Tension Glaucoma (NTG)CompletedNCT02863705Phase 41 country
- Evaluation of Blood Flow Regulation With Laser Speckle FlowgraphyStatus unknownNCT03391518Not applicable1 country
- Serum Bilirubin Levels in Normal-tension GlaucomaCompletedNCT033873061 country
- Pressure Difference Between Brain and Eye: a Possible Cause to Normal Tension Glaucoma.CompletedNCT027764491 country
- Metabolomics in Surgical Ophthalmological PatientsStatus unknownNCT030983161 country
- Effect of Alphagan on Retinal Blood Flow Autoregulation and Motion Detection in Patients With Normal Pressure GlaucomaCompletedNCT01105065Not applicable1 country
- A New View of Normal Tension Glaucoma: Autoregulation and Systemic Blood PressureCompletedNCT007060561 country
- Does the Optic Disc Grading Done Visually by Your Doctor Agree With Optic Nerve Testing Which is Done by Machines?CompletedNCT004302871 country
- Will Listening to Music Make it Easier to Take a Visual Field Test?CompletedNCT010270391 country
- Pilot Study on Ambulatory Intraocular Pressure and Blood Pressure Monitoring in GlaucomaCompletedNCT01912599Not applicable1 country
- Relationship Between 24-hour IOP Pattern and the 24-hour Blood Pressure Pattern in Patients With POAGCompletedNCT01769521Not applicable1 country
- Investigation of Intraocular Pressure (IOP) Reduction Efficacy of Travoprost Ophthalmic Solution in Patients With Normal Tension GlaucomaCompletedNCT01995136Phase 41 country
- Ocular Blood Flow in Glaucoma Patients - the Leuven Eye StudyCompletedNCT018402021 country
- Study on the Oxygen Saturation in Pulsating and Non-pulsating Central Retinal VeinsStatus unknownNCT017944421 country
- Intraocular Pressure and Hemodialysis Midwestern BrazilCompletedNCT02405884Not applicable
- Intraocular Pressure and Ocular Perfusion Pressure of Cosopt in Normal Tension GlaucomaCompletedNCT01175902Not applicable1 country