CClinicalTrials.gg
Not yet recruitingNCT07804277Updated Sep 9, 2026

Comparative Study of the Tomey FT-1000, and Goldmann Applanation Tonometer (GAT)

An observational study in Glaucoma, sponsored by Tomey Corporation. Not yet recruiting. Open to participants aged 22 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-09.

Sponsored by Tomey Corporation · Observational

Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
30
Ages
22 Years and older
Sex
All
01

Study summary

This study is intended to evaluate the agreement between Intraocular pressure(IOP) measurements obtained with the FT-1000 non-contact tonometer and a GAT to confirm the feasibility of the measurement procedures.

This is a prospective comparative study that will be conducted at one clinical site in the United States. Subjects who sign an informed consent form and fulfill all inclusion and exclusion criteria will undergo FT-1000 measurements followed by Goldmann applanation tonometry during a single study visit.

The primary analysis will be performed using one preselected study eye from each subject. Measurements from the fellow eye, when available, may be summarized as exploratory analyses but will not contribute to the primary effectiveness analysis.

In general, descriptive statistics (n, mean, standard deviation, median, minimum and maximum) will be used to summarize continuous variables. Frequencies and percentages will be used to summarize categorical variables. The number of accepted scans and the total number of scans evaluated will be summarized by scan type, device, and subject population.

Agreement between the FT-1000 and the Goldmann applanation tonometer will be evaluated using the study eye measurements by calculating the mean difference, standard deviation (SD), 95% limits of agreement (LOA), Bland-Altman plots, Deming regression, and Pearson correlation coefficient.

Exploratory analyses may also be performed using fellow-eye measurements.

02

Conditions studied

  • Glaucoma

Browse trials for

03

Who can participate

Ages eligible
22 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Low Intraocular pressure(IOP) (22 years old or older) Middle Intraocular pressure(IOP)(22 years old or older) High Intraocular pressure(IOP)(22 years old or older)

Inclusion criteria

  1. Male or female subjects 22 years of age or older who have full legal capacity to volunteer on the date the informed consent is signed.
  2. Subjects who are able to understand and follow the study procedures and instructions provided by the clinical staff.
  3. Subjects who voluntarily provide written informed consent.
  4. Subjects who satisfy all study eligibility requirements and are able to undergo both FT-1000 and Goldmann applanation tonometry measurements during the study visit.

Exclusion criteria

Exclusion Criteria:

  1. Subjects with only one functional eye.
  2. Subjects with poor or eccentric fixation in either eye.
  3. Subjects with a history of corneal surgery, including corneal laser or refractive surgery (e.g., LASIK).
  4. Subjects with corneal scarring, keratoconus, or any other clinically significant corneal pathology.
  5. Subjects with an active corneal or conjunctival infection or inflammation in either eye.
  6. Subjects with microphthalmos or buphthalmos.
  7. Subjects who are unable or unwilling to remove contact lenses before study measurements.
  8. Subjects with clinically significant dry eye disease that, in the investigator's opinion, may affect tonometry measurements.
  9. Subjects with blepharospasm (lid squeezing) or nystagmus that may interfere with accurate measurements.
  10. Subjects with abnormal central corneal thickness (CCT).
  11. Subjects with any condition or circumstance that, in the opinion of the investigator, could place the subject at significant risk, interfere with study participation, or confound interpretation of the study results.
04

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
30 participants (estimated)
Patient registry
No

Groups and cohorts

  • Low Intraocular pressure(IOP) Group: 7-16 mmHg

    Group with IOP of 7-16 mmHg; 10 subjects.

    Device: Non Contact Tonometer and Applanation Tonometer

  • Middle Intraocular pressure(IOP) Group: >16 to <23 mmHg

    Group with IOP of \>16 to \<23 mmHg; 10 subjects.

    Device: Non Contact Tonometer and Applanation Tonometer

  • High Intraocular pressure(IOP)Group: ≥23 mmHg

    Group with IOP of ≥23 mmHg; 10 subjects.

    Device: Non Contact Tonometer and Applanation Tonometer

Interventions

  • DeviceNon Contact Tonometer and Applanation Tonometer

    Intraocular pressure measurement by non-contact tonometer and applanation tonometer.

05

What researchers measure

Primary outcomes

  1. Agreement of the Intraocular pressure (IOP) mmHg between the test devices and predicate device

    Agreement of the Intraocular pressure (IOP) mmHg between the FT-1000 and the Goldmann Applanation Tonometer(GAT) will be evaluated using the study eye measurements by calculating the mean difference, standard deviation (SD), 95% limits of agreement (LOA), Bland-Altman plots, Deming regression, and Pearson correlation coefficient. Exploratory analyses may also be performed using fellow-eye measurements.

    Time frame: Through study completion, approximately 3 days

  2. Safety of the test devices

    Any adverse events observed or reported during the study visit will be assessed and documented.

    Time frame: Through study completion, approximately 3 days

06

Study locations

No study locations are listed for this record.

07

Registry details

Key details

Study ID
NCT07804277
Lead sponsor
Tomey Corporation
Responsible party
Sponsor
First posted
Sep 4, 2026
Start date
Sep 24, 2026 (estimated)
Primary completion
Sep 28, 2026 (estimated)
Completion
Sep 28, 2026 (estimated)
Last update
Sep 9, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion