AbbVie: Glaucoma trials

The registry lists 73 Glaucoma studies with AbbVie as lead sponsor. 0 are open to participants now and 54 have results posted.

Phase 1 3Phase 2 8Phase 3 21Phase 4 20No phase 23(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT04285580Phase 3Results posted
• Chart Review of XEN 45 Gel Stent: Long Term Performance and Safety Assessment (XEN LT)CompletedNCT03868254Results posted
• XEN-45 Gel Stent Versus Trabeculectomy in Glaucoma: Gold-Standard Pathway Study (GPS)CompletedNCT03654885Phase 4Results posted
• Safety and Effectiveness of the XEN45 Glaucoma Treatment System in Patients With Angle Closure GlaucomaCompletedNCT03362931Phase 3Results posted
• A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT02636946Phase 3Results posted
• Comparison of Bimatoprost Sustained Release (SR) to Selective Laser Trabeculoplasty (SLT) in Adults With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT02507687Phase 3Results posted
• Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT02250651Phase 3Results posted
• Efficacy and Safety Study of Bimatoprost Sustained-Release (SR) in Participants With Open-angle Glaucoma or Ocular HypertensionCompletedNCT02247804Phase 3Results posted
• Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular HypertensionCompletedNCT02097719Phase 4Results posted
• A Study of Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular HypertensionCompletedNCT02061683Phase 4Results posted
• A Study of 0.03% Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular HypertensionCompletedNCT02020512Phase 4Results posted
• A Study of 0.15% Brimonidine Tartrate in Patients With Primary Open Angle Glaucoma and Ocular HypertensionCompletedNCT02003534Phase 4Results posted
• A Study of GANFORT® UD in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) in a Medical SettingCompletedNCT01999348Results posted
• An Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular HypertensionCompletedNCT01881126Phase 4Results posted
• A Safety and Efficacy Study of Fixed-Combination Bimatoprost and Brimonidine in Chronic Glaucoma or Ocular HypertensionCompletedNCT01863953Phase 2Results posted
• A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Switched to Lumigan® UD Monotherapy for Medical ReasonsCompletedNCT01853085Results posted
• A Safety Study of Bimatoprost in Patients With Glaucoma or Ocular HypertensionCompletedNCT01830140Phase 3Results posted
• A Study of Quantitative Assessments of Angle Width in Chinese Patients With Open-angle Glaucoma and/or Ocular HypertensionTerminatedNCT01781962Results posted
• An Observational Study of Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) Who Switched IOP-lowering TreatmentsCompletedNCT01735214Results posted
• A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Were Insufficiently Responsive to MonotherapyCompletedNCT01637246Results posted
• A Study of Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)CompletedNCT01632423Results posted
• A Study of Intraocular Pressure (IOP) Reduction in Newly Diagnosed Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)CompletedNCT01628614Results posted
• GANfort® in Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Are Insufficiently Responsive to MonotherapyCompletedNCT01628601Results posted
• Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)CompletedNCT01628588Results posted
• A Safety and Efficacy Study of Bimatoprost 0.01% in Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OH)CompletedNCT01594970Phase 4Results posted
• A Study of Lumigan® 0.01% in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)CompletedNCT01589510Results posted
• Observational Study of Lumigan® 0.01% for Treatment of Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)CompletedNCT01568008Results posted
• Study Comparing Quantitative Assessments in Open-angle Glaucoma (OAG) and/or Ocular Hypertension (OHT)CompletedNCT01540370Results posted
• A Safety and Efficacy Study of ALPHAGAN® P and LUMIGAN® in Subjects Previously Treated With Latanoprost for Glaucoma and Ocular HypertensionCompletedNCT01525173Phase 4Results posted
• Observational Study of Lumigan® 0.01% Treatment for Patients With Primary Open Angle Glaucoma or Ocular HypertensionCompletedNCT01489670Results posted
• A Study of the Safety and Efficacy of Bimatoprost Ophthalmic Solution in Paediatric Patients With GlaucomaTerminatedNCT01426113Phase 3Results posted
• Long-Term Safety of Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular HypertensionCompletedNCT01298700Phase 4Results posted
• Safety and Efficacy of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT01291108Phase 2Results posted
• Ocular Surface Tolerability Study of Prostaglandin Analogues in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT01253902Phase 4Results posted
• Safety and Efficacy of Bimatoprost/Timolol Fixed Combination Versus Latanoprost in Patients With Open-Angle Glaucoma Who Have Never Been TreatedCompletedNCT01243567Phase 4Results posted
• Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular HypertensionCompletedNCT01241240Phase 3Results posted
• Safety and Efficacy of Brimonidine Tartrate/Timolol Fixed Combination in Patients With Glaucoma or Ocular HypertensionCompletedNCT01229462Not applicableResults posted
• Safety and Efficacy of Triple Combination Therapy in Patients With Primary Open-Angle Glaucoma or Ocular HypertensionCompletedNCT01217606Phase 3Results posted
• Safety and Efficacy of Triple Combination Therapy in Patients With Glaucoma or Ocular HypertensionCompletedNCT01216943Phase 3Results posted
• Safety and Pharmacodynamics Study of AGN-207281 Ophthalmic Solutions Compared With Timolol Ophthalmic Solution or Placebo in Patients With Ocular Hypertension or Primary Open-Angle GlaucomaCompletedNCT01215786Phase 1Results posted
• Safety and Efficacy of a New Formulation of Bimatoprost/Timolol Ophthalmic Solution Compared With Bimatoprost/Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular HypertensionCompletedNCT01177098Phase 3Results posted
• Comparing Safety and Efficacy of Combigan® and Lumigan® With Lumigan® Alone in Glaucoma or Ocular Hypertension Subjects Treated With Xalatan®CompletedNCT01170884Phase 4Results posted
• Safety and Efficacy of a New Ophthalmic Formulation of Bimatoprost in Patients With Open Angle Glaucoma and Ocular HypertensionCompletedNCT01157364Phase 1/2Results posted
• Study of Brimonidine and Timolol Ophthalmic Solution With Latanoprost Compared With Latanoprost in Glaucoma PatientsTerminatedNCT01151904Phase 4Results posted
• Safety and Efficacy of AGN-210961 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular HypertensionCompletedNCT01110499Phase 2Results posted
• Safety and Efficacy of Different Formulations of Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular HypertensionCompletedNCT01099774Phase 3Results posted
• Safety and Efficacy of Bimatoprost Timolol Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular HypertensionCompletedNCT01068964Not applicableResults posted
• Comparing Effects of Two Fixed Combinations Ophthalmic Solutions on Ocular Blood FlowCompletedNCT00811850Phase 4Results posted
• An Evaluation of the Fixed Combination Brimonidine Tartrate 0.2%/ Timolol Maleate 0.5% to Latanoprost 0.005% in Glaucoma or Ocular Hypertension SubjectsCompletedNCT00811564Phase 4Results posted
• Safety and Efficacy of AGN 210669 Ophthalmic Solution in Patients With Ocular Hypertension or Primary Open-Angle GlaucomaCompletedNCT00809848Phase 1/2Results posted
• Comparing Efficacy and Safety of Combigan With Timolol Adjunctive to Xalatan in Glaucoma or Ocular Hypertension SubjectsCompletedNCT00735449Phase 4Results posted
• Safety and Efficacy Study of Bimatoprost, Latanoprost, and Travoprost in Patients With Elevated Intraocular Pressure (IOP) and Open-angle Glaucoma (OAG)CompletedNCT00716742Results posted
• Safety and Efficacy of Bimatoprost Compared With Latanoprost in Patients With Glaucoma or Ocular HypertensionCompletedNCT00541242Phase 4Results posted
• A Study of the Safety and Efficacy of Bimatoprost in Patients With Glaucoma or Ocular HypertensionCompletedNCT00538304Phase 2Results posted
• Study to Assess Change in Disease Activity and Adverse Events of Ab Externo Approach for Glaucoma Gel Stent (XEN45) Implantation In Participants Aged 45 Years or Older With Open-Angle GlaucomaCompletedNCT05411198Phase 3
• Real-world Evidence Study of XEN in Chinese Patients With Refractory GlaucomaCompletedNCT04303897
• Satisfaction With XEN Gel Stent Versus Trabeculectomy for the Treatment of GlaucomaCompletedNCT03852810
• Efficacy and Safety of COMBIGAN® in Korean Patients With Primary Open Angle Glaucoma (POAG) and Normal Tension Glaucoma (NTG)CompletedNCT02863705Phase 4
• Safety of GANFORT® Ophthalmic Solution in Chinese Patients With Open-angle Glaucoma or Ocular HypertensionCompletedNCT02571712Phase 4
• A Study of Simbrinza™ Therapy in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT02348476
• Comparison of Efficacy & Tolerability Between Ganfort vs Krytantek in Mexican Patients With Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OHT)CompletedNCT01737853
• A Study of the Rate of Progression of Glaucoma During a Follow-up Period of Two YearsCompletedNCT01629407
• Safety and Efficacy of Triple Combination Therapy With Dorzolamide Hydrochloride / Brimonidine Tartrate / Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular HypertensionWithdrawnNCT01284166Phase 3
• Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT00822055Phase 4
• Safety and Efficacy Study of Different Formulations of Bimatoprost Once-Daily in Patients With Glaucoma or Ocular HypertensionCompletedNCT00652496Phase 2
• Safety and Efficacy Study of Brimonidine in Patients With Glaucoma or Ocular HypertensionCompletedNCT00652483Phase 3
• Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular HypertensionCompletedNCT00652106Phase 3
• Safety and Efficacy Study of Bimatoprost in Ethnically Japanese Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT00651859Phase 2
• Study to Evaluate Safety of Brimonidine/Timolol Fixed Combination in Glaucoma or Ocular Hypertension PatientsCompletedNCT00651612Phase 3
• Internet-based, Naturalistic Evaluation of Tolerability and Individual Patient Target Pressures With Bimatoprost 0.03% in GlaucomaCompletedNCT00487214
• Safety and Efficacy of Brimonidine in Patients With Glaucoma or Ocular HypertensionCompletedNCT00168363Phase 3
• Memantine in Patients With Chronic GlaucomaCompletedNCT00168350Phase 3
• Memantine in Patients With Chronic GlaucomaCompletedNCT00141882Phase 3