ClinicalTrials.gg
Sign In

Gastroesophageal Reflux clinical trials

The registry lists 1,211 studies for Gastroesophageal Reflux across more than 10 countries. 202 are recruiting or about to start. 868 of them are mainly about Gastroesophageal Reflux (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 3 narrower conditions too, such as Laryngopharyngeal Reflux: 1,301 studies, 218 open.

ClinicalTrials.gov finds 1,557 studies for Gastroesophageal Reflux. How that becomes 1,210 here

This page counts the studies the registry files under Gastroesophageal Reflux, and those it files under no condition that list Gastroesophageal Refluxthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 1,557Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −84Filed under a narrower condition, counted on its own pageLaryngopharyngeal Reflux 33 · Non-Erosive Reflux Disease 27 · Respiratory Aspiration of Gastric Contents 21
  3. −9List Gastroesophageal Reflux as a condition, but the registry did not file them under itMost often written as “Hiatal Hernia With Gastroesophageal Reflux Disease” (3), “Non-Erosive Gastro-Esophageal Reflux Disease” (2), and “Gastroesophageal Reflux Disease With Hiatal Hernia” (1). The registry filed them under other conditions only, most often Hernia, Hiatal (3) and Heartburn (3).
  4. −257Match it another way43 name it in the title, 3 in a keyword, and 211 by a synonym or other text the search reads.
  5. 1,207Counted here and found by its search31 of them list Gastroesophageal Reflux in their own words; the registry filed them under no condition.
  6. +3
    Counted here, but its search does not find them
  7. 1,210The count on this page

Get an email when these change. Save the Gastroesophageal Reflux studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

Watch these studies
See an example email

Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

One email a week for all your saved searches. Stop any time.

Status

Completed
697
Status unknown
140
Recruiting
132
Terminated
81
Not yet recruiting
55
Withdrawn
54

Phase

Phase 3
124
Phase 4
118
Phase 2
85
Phase 1
85
Early Phase 1
6

Where

United States
419
Italy
78
Germany
70
France
62
Korea, Republic of
56
China
55

Who runs them

AstraZeneca (89) · Takeda (35) · Mayo Clinic (30) · Asian Institute of Gastroenterology, India (14) · Chinese University of Hong Kong (14) · Universitaire Ziekenhuizen KU Leuven (11) · Johns Hopkins University (11) · Midwest Biomedical Research Foundation (10)

What is being tested here

Drugs under test in Gastroesophageal Reflux studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Vonoprazan5114
Tegoprazan305
Omeprazole2119
Lidocaine214
Famotidine213
Esomeprazole11565
Lansoprazole1123
Domperidone139
Linaprazan glurate117
Amitriptyline102

Drug classes tested here Proton pump inhibitors (PPIs) 6 open · H2 blockers 2 open · Antiemetics 1 open · Serotonin receptor agonists 1 open · SSRIs 1 open

Coming up

6phase 3 studies under way
67studies finish main data collection within a year2 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 132 Gastroesophageal Reflux studies recruiting now, 56 (42%) set no upper age limit and 53 (40%) stop at 75 or younger. 22 (17%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 20 (15%) take healthy volunteers.

Recruiting studies that take each age, of 132
AgeWomenMen
109 (7%)9 (7%)
18104 (79%)104 (79%)
30115 (87%)115 (87%)
40117 (89%)117 (89%)
50117 (89%)117 (89%)
65108 (82%)108 (82%)
7590 (68%)90 (68%)
8569 (52%)69 (52%)

Across all 1,211 studies, recruiting or not: 46% stop at 75 or younger and 29% at 65; 18% take children; <1% are for women only and 1% for men only; 21% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Gastroesophageal Reflux studies take

Of 34 phase 1 interventional studies under Gastroesophageal Reflux, half reached primary completion within 4 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 14 mo2–10 · 34 studies4 mo1–6 · 28 studies—
Phase 215 mo13–52 · 14 studies——
Phase 319 mo12–49 · 20 studies——
Phase 428 mo15–53 · 30 studies——
Interventional, no phase32 mo12–68 · 225 studies33 mo21–59 · 33 studies31 mo11–68 · 192 studies
Observational45 mo17–167 · 116 studies—57 mo18–167 · 95 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Started recruiting2

Newly registered7

Show 2 more

Studies

Recruiting first, then most recently updated. Showing 50 of 1,211. Browse all 1,211 → or search them.