An observational study in GERD, sponsored by Asian Institute of Gastroenterology, India. Completed at 1 site in India. Open to participants aged 18 Months to 50 Months. Per ClinicalTrials.gov, last updated 2026-11-05.
Sponsored by Asian Institute of Gastroenterology, India · Observational
This prospective, single-center study at AIG Hospitals, Hyderabad, aims to establish normal 24-hour ambulatory esophageal pH-impedance values, including acid exposure time (AET), in 50 healthy Indian adults. Current Western diagnostic cut-offs may not be applicable to the Indian population, where normal AET is likely lower. Healthy volunteers aged 18-50 with no GI symptoms or systemic diseases will undergo baseline evaluations, high-resolution manometry, and 24-hour pH-impedance monitoring while maintaining regular activities. The study will assess how diet, body position, and sleep affect reflux, with statistical analysis to determine normative values for improved GERD diagnosis in India.
1,211 studies on the registry are indexed under Gastroesophageal Reflux; 202 are open to participants now.
This study's enrollment of 50 is below the median of 178 across 348 observational studies indexed under Gastroesophageal Reflux.
Browse Gastroesophageal Reflux studies →Asian Institute of Gastroenterology, India is the lead sponsor of 135 studies on the registry; 59 are open to participants now.
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This study will include adults aged 18-50 years with GERD symptoms
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Age ≥18 years.
Symptoms of GERD (heartburn, regurgitation, chest pain) diagnosed using:
Clinical symptoms based on validated questionnaires. Endoscopic findings (e.g., esophagitis, Barrett's esophagus). Provide written .
Exclusion Criteria:
Pregnant women or breast-feeding women
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
To correlate the subjective (GERD HRQL scores) and objective (Endoscopy, Esophageal manometry and 24-hour pH- impedance monitoring) parameters of GERD
Time frame: 12 months
To develop predective models for forecasting manometric and pH findings
Time frame: 12 months
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.
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Asian Institute of Gastroenterology, India →