Drug
Vonoprazan clinical trials
Also written TAK-438, Takecab and vocinti.
- studies test it
- 99
- open now
- 20
- in phase 3
- 33
- first study started
- 2007
Keep track of what changes. Save the vonoprazan studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
- TAK-438
- 31
Studies by the year they started
98 studies that test it; most in 2021 (14)
| Year | Studies |
|---|---|
| 2007 | 2 |
| 2008 | 2 |
| 2010 | 1 |
| 2011 | 8 |
| 2012 | 5 |
| 2015 | 2 |
| 2016 | 4 |
| 2017 | 4 |
| 2018 | 1 |
| 2019 | 5 |
| 2020 | 4 |
| 2021 | 14 |
| 2022 | 10 |
| 2023 | 7 |
| 2024 | 12 |
| 2025 | 12 |
| 2026 | 5 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 23
- Phase 2
- 7
- Phase 3
- 33
- Phase 4
- 25
- No phase
- 12
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 50 · Other 49
Takeda (33) · Phathom Pharmaceuticals, Inc. (14) · Shandong University (5) · Nanjing First Hospital, Nanjing Medical University (3) · Alexandria University (3) · Asian Institute of Gastroenterology, India (3) · Fu Jen Catholic University Hospital (2) · Xijing Hospital of Digestive Diseases (2)
Often tested with
Tested in the same studies.
Amoxicillin (17) · Clarithromycin (7) · Esomeprazole (5) · Levofloxacin (4) · Tetracycline (4) · Metronidazole (3) · Bismuth (3) · Lansoprazole (3)
Studies
Open first, then newest update. How each study uses vonoprazan is read from its arms, and is right about nine times in ten.
Testing it · 99
- A Study to Evaluate the Efficacy and Safety of Vonoprazan 10 mg Compared to Placebo for Relief of Episodic Heartburn in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease Through 24 WeeksRecruitingPhase 3Phathom Pharmaceuticals, Inc.NCT07752407Written as Vonoprazan
- Vonoprazan-Amoxicillin Dual Therapy for Helicobacter Pylori Infection in United States AdolescentsNot yet recruitingPhase 2Boston Children's HospitalNCT07860112Written as Vonoprazan
- Comparative Study Evaluating Safety and Effectiveness of ( Proton Pump Inhibitor Versus Vonoprazan ) Based Triple Therapy With or Without Zinc to Eradicate H. Pylori InfectionRecruitingPhase 3Tanta UniversityNCT07275827Written as Vonoprazan + amoxicillin + clarithromycin
- Comparison of Rabeprazole and Vonoprazan in the Prevention of Post-endoscopic Variceal Ligation Ulcer in Patients With CirrhosisNot yet recruitingPhase 3King George's Medical UniversityNCT07608536Written as Vonoprazan
- Simplified Dual Regimen Guided by Fecal Clarithromycin Resistance Gene Detection for First-line H. Pylori EradicationRecruitingNot applicablePeking University First HospitalNCT07439445Written as Vonoprazan 20 mg twice daily + clarithromycin 500 mg twice daily for 14 days
- Vonaprazan Versus Esomeprazole for Healing of LA Grade B or Higher Esophagitis After POEMRecruitingNot applicableAsian Institute of Gastroenterology, IndiaNCT06955520Written as Vonoprazan
- PPI Infusion Versus Oral Acid Pump Inhibitors for Bleeding Peptic UlcersRecruitingPhase 4Chinese University of Hong KongNCT05582174Written as Vonoprazan
- A Randomized, Three-Arm Study Comparing Vonaprazan 10 mg, Vonaprazan 20 mg, and Esomeprazole 40 mg for the Healing of LA Grade B or Higher Reflux Esophagitis at 8 WeeksRecruitingNot applicableAsian Institute of Gastroenterology, IndiaNCT06953986Written as Vonoprazan
- Vonoprazan Test for PPI Refractory GERDEnrolling by invitationNot applicableFu Jen Catholic University HospitalNCT07437768Written as Patients received a 4-week treatment of vonoprazan 20 mg once daily (VOCINTI®)
- Efficacies of Bismuth-amoxicillin-vonoprazan Triple Therapy, Vonoprazan-amoxicillin Dual Therapy and Proton Pump Inhibitor-based Standard Triple Therapy for Hp EradicationRecruitingNot applicableKaohsiung Medical UniversityNCT06349486Written as vonoprazan, amoxicillin
- Evaluating the Efficacy of Vonoprazan in Preventing Post-Endoscopic Variceal Band Ligation Ulcers: A Randomized Controlled TrialRecruitingPhase 2King Edward Medical UniversityNCT07267260Written as Vonoprazan 20 mg
- The Effects of Vonoprazan Fumarate on DGF Incidence in DD Kidney Transplant RecipientsRecruitingPhase 1/2First Affiliated Hospital of Chongqing Medical UniversityNCT07275632Written as Vonoprazan fumarate
- Head-to-head Study of Tegoprazan 50 mg BID Plus Amoxicillin 1 g TID vs. Vonoprazan 20 mg BID Plus Amoxicillin 1 g TID for H. Pylori EradicationRecruitingPhase 2/3First People's Hospital of HangzhouNCT07242456Written as Vonoprazan
- Comparison of Omeprazole vs Vonoprazon in Treatment of H Pylori InfectionNot yet recruitingPhase 4Rehman Medical Institute - RMINCT07040839Written as Vonoprazan 20 mg
- Vonoprazan Evaluation Compared to Standard Triple Therapy in Helicobacter Pylori eRadicationRecruitingPhase 4Asian Institute of Gastroenterology, IndiaNCT06959368Written as Vonoprazan 20mg, Esomeprazole 40 mg, Amoxicillin 1 g, Clarithromycin 500 mg
- Indonesian Study of Vonoprazan Vs Esomeprazole in Erosive EsophagitisNot yet recruitingPhase 4Indonesia UniversityNCT06720610Written as Vonoprazan 20 mg
- Efficacy of Different Durations of Dual and Quadruple Regimens for Helicobacter Pylori EradicationRecruitingPhase 4Shandong UniversityNCT06723197Written as vonoprazan+amoxicillin
- Clinical Study Evaluating The Role of Vonoprazan Versus Pantoprazole in Patients With Gastroesophageal Reflux DiseaseRecruitingPhase 4Tanta UniversityNCT06564246Written as Vonoprazan 20 mg versus Pantoprazole 40 mg
- Triple Versus Quadruple Therapy for the Eradication of Helicobacter PyloriEnrolling by invitationNot applicableShandong UniversityNCT06299605Written as Vonoprazan-Amoxicillin-Tetracycline-Bismuth quadruple regimen for 14 days
- Efficacy and Safety of Vonorasan Versus Esomeprazole in the Treatment of Ulcers After Endoscopic Submucosal DissectionNot yet recruitingPhase 4Shicai YeNCT06526455Written as Vonoprazan
See all 99 studies that test vonoprazan →
Given in every arm · 13 — vonoprazan is usual care beside what is tested
- Efficacy Comparison of Vonoprazan Combined With Different Antibiotics in Dual Therapy for Helicobacter Pylori Eradication: A Prospective, Randomized Controlled Clinical TrialRecruitingPhase 4Yongquan ShiNCT07068607Written as Vonoprazan
- Zuojin Wan Combined with Vonoprazan-Amoxicillin Dual Therapy in H.Pylori EradicationNot yet recruitingEarly Phase 1Nanjing First Hospital, Nanjing Medical UniversityNCT06901375Written as Vonoprazan
- Efficacy and Safety of Black Seed Oil With Vonoprazan Based Triple Therapy in Treatment of Helicobacter PyloriActive, not recruitingPhase 2Ain Shams UniversityNCT05957432Written as Vonoprazan, Amoxicillin and Clarithromycin
- Optimization of Minocycline for Helicobacter Pylori Rescue TreatmentCompletedPhase 4Shanghai Jiao Tong University School of MedicineNCT06561711Written as Vonoprazan
- Banxiaxiexin Decoction Combined With Vonoprazan-Amoxicillin Dual Therapy in H. Pylori EradicationCompletedPhase 3Nanjing First Hospital, Nanjing Medical UniversityNCT06340724Written as Vonoprazan
- Rescue Therapy for Helicobacter Pylori InfectionCompletedPhase 4Shanghai Jiao Tong University School of MedicineNCT05874544Written as Vonoprazan
- Helicobacter Rescue Therapy With Vonorazon and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple TherapyCompletedPhase 4Yongquan ShiNCT06168084Written as Vonoprazan
- The Effects of High-dose Dual Therapy With Probiotics on Gut Microbiota for Helicobacter Pylori Rescue TreatmentCompletedNot applicableZhongshan Hospital (Xiamen), Fudan UniversityNCT06292546Written as Vonoprazan
- High-dose Dual Therapy and Minocycline-cotaining Quadruple Therapy for Helicobacter Pylori InfectionStatus unknownPhase 4Shanghai Jiao Tong University School of MedicineNCT06561698Written as Vonoprazan
- Efficacy and Safety of Dual Therapy as First-line Treatment for Hp InfectionStatus unknownPhase 4Second Affiliated Hospital, School of Medicine, Zhejiang UniversityNCT05419674Written as Vonoprazan
- The Effect of Probiotics on Gut Microbiotain After Helicobacter Pylori EradicationStatus unknownPhase 4Nanjing First Hospital, Nanjing Medical UniversityNCT05658055Written as Vonoprazan
- Comparison of Vonoprazan-based Dual and Triple Therapies for H. Pylori EradicationCompletedPhase 3Hamamatsu UniversityNCT02827942Written as vonoprazan 20 mg bid
- Phase 3 Study to Evaluate the Acid-Inhibitory Effect of Multiple Oral Doses of Vonoprazan (TAK-438)CompletedPhase 3TakedaNCT02037477Written as Vonoprazan
As the comparator · 4 — what is tested is compared with vonoprazan
- Vonoprazan Alone vs With Itopride for Functional Dyspepsia: The VIVA TrialRecruitingNot applicableAsian Institute of Gastroenterology, IndiaNCT07731542Written as Vonoprazan
- Vonoprazan High-Dose Dual VS Levofloxacin ConcomitantNot yet recruitingPhase 4Damascus HospitalNCT07624422Written as Vonoprazan
- Vonoprazan-containing Triple Therapy Versus Empiric Bismuth Quadruple Therapy for First-line Helicobacter Pylori Treatment: a Randomized Clinical TrialNot yet recruitingPhase 4Shanghai East HospitalNCT05726734Written as Vonoprazan
- Comparison of the Efficacies of Two Novel Dose Dual Therapies in the First-line Helicobacter Pylori EradicationStatus unknownPhase 3Chang Gung Memorial HospitalNCT06811207Written as Vonoprazan
Codes
What other systems call vonoprazan · ClinicalTrials.gg INT005725
- MeSH (NLM) C552956vonoprazanOne source NLM
- UNII (FDA) 1R5L3J156GVONOPRAZANConfirmed FDA, NLM, Wikidata
- RxNorm 2604577One source FDA
- Wikidata Q27887191vonoprazanConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C152911VonoprazanOne source FDA
- DrugBank DB11739One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C552956 | vonoprazan | One source NLM |
| UNII (FDA) | 1R5L3J156G | VONOPRAZAN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 2604577 | — | One source FDA |
| Wikidata | Q27887191 | vonoprazan | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C152911 | Vonoprazan | One source FDA |
| DrugBank | DB11739 | — | One source Wikidata |
Also registered as vonoprazan fumarate (UNII 4QW3X4AMLB · RxNorm 2604576).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.