Dyslexia clinical trials
The registry lists 127 studies for Dyslexia across more than 10 countries. 27 are recruiting or about to start. 91 of them are mainly about Dyslexia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.
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Status
Who runs them
IRCCS Eugenio Medea (8) · Catholic University of the Sacred Heart (6) · Vanderbilt University (5) · Hospices Civils de Lyon (4) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (4) · Poppins (3) · Education University of Hong Kong (3) · University Hospital, Toulouse (3)
What is being tested here
Drugs under test in Dyslexia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Atomoxetine | 0 | 0 | 4 |
| Lovastatin | 0 | 0 | 1 |
| Lidocaine | 0 | 0 | 1 |
| Methylphenidate | 0 | 0 | 1 |
| Guanfacine | 0 | 0 | 1 |
| Levodopa | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6
- Dec 2026Personalization of Visual Characters and Text-to-Speech (TTS) to Support Learning in Students With Reading Difficulties · IRCCS Eugenio Medea
- Jan 2027Interventions for Reading Disabilities in NF1 · Vanderbilt University
- Jan 2027Pai.ACT: AI-Driven ACT Chatbot for Mental Health Triage and Service Evaluation · Chinese University of Hong Kong
- Jun 2027Enhancing Letter-Speech Sound Learning and Reading Network Activation With Transcranial Electrical Stimulation · Silvia Brem
- Jun 2027Intervention Effectiveness Study of BEtter AT LEarning (BEATLE)- Digital Neuropsychological Rehabilitation Program · Helsinki University Central Hospital
- Jul 2027Brain Stimulation With Combined Reading and Motor Training for Children With Dyslexia · Shahid Beheshti University
Who these studies take
Of the 18 Dyslexia studies recruiting now, 2 (11%) set no upper age limit and 14 (78%) stop at 75 or younger. 13 (72%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 11 (61%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 7 (39%) | 7 (39%) |
| 18 | 7 (39%) | 7 (39%) |
| 30 | 6 (33%) | 6 (33%) |
| 40 | 5 (28%) | 5 (28%) |
| 50 | 5 (28%) | 5 (28%) |
| 65 | 4 (22%) | 4 (22%) |
| 75 | 4 (22%) | 4 (22%) |
| 85 | 4 (22%) | 4 (22%) |
Across all 127 studies, recruiting or not: 87% stop at 75 or younger and 85% at 65; 82% take children; 0% are for women only and 3% for men only; 49% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Dyslexia studies take
Of 69 interventional studies with no phase under Dyslexia, half reached primary completion within 24 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 24 mo9–57 · 69 studies | — | 24 mo10–57 · 62 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Results posted1
- Neurocognitive Factors in EdTech Intervention ResponseOct 20, 2026NCT04568824
Studies
Recruiting first, then most recently updated. Showing 50 of 127. Browse all 127 → or search them.
- taVNS for Letter Learning in DyslexiaEnrolling by invitationNCT06127550Not applicable1 country
- Brain Stimulation Paired With Structured Reading Instruction in Children With DyslexiaEnrolling by invitationNCT07762365Not applicable1 country
- Personalization of Visual Characters and Text-to-Speech (TTS) to Support Learning in Students With Reading DifficultiesRecruitingNCT06947512Not applicable1 country
- Dynamic Assessment of the Risk for Language and Reading Disorders in Monolingual and Multilingual ChildrenRecruitingNCT06937255Not applicable1 country
- Immediate Effects of Active Prisms on Reading Automaticity and Motor Control in Young Adults With Developmental DyslexiaNot yet recruitingNCT07868367Not applicable1 country
- Brain Stimulation With Combined Reading and Motor Training for Children With DyslexiaNot yet recruitingNCT07781761Not applicable1 country
- Executive Function in Early ChildhoodEnrolling by invitationNCT03713125Not applicable1 country
- Combined Exercise and Targeted Therapy for Post-Stroke Reading DeficitsRecruitingNCT06213272Not applicable1 country
- Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered SpeechRecruitingNCT07459803Not applicable1 country
- Validating a Neurocognitive Remediation Model for Visual-Attentional Pathway in Chinese Developmental DyslexiaRecruitingNCT07707700Not applicable1 country
- Enhancing Letter-Speech Sound Learning and Reading Network Activation With Transcranial Electrical StimulationRecruitingNCT07546292Not applicable1 country
- Dual Executive Function Training PackageRecruitingNCT07262853Not applicable1 country
- Reading-FREE Markers for Early Detection of Developmental DyslexiaEnrolling by invitationNCT07072104Not applicable1 country
- Intervention Effectiveness Study of BEtter AT LEarning (BEATLE)- Digital Neuropsychological Rehabilitation ProgramRecruitingNCT06713863Not applicable1 country
- Evaluation of Speech Rhythm Training in Dyslexic Readers Aged 7 to 9 YearsRecruitingNCT05996497Not applicable1 country
- Reading and StutteringNot yet recruitingNCT06836115
- ReadMap: Reading in Stroke Alexia and Typical AgingRecruitingNCT067000051 country
- A Game-based Neurodevelopmental Assessment for Young ChildrenRecruitingNCT057808531 country
- A Strength-Based Intervention to Improve Job Interview Skills in Neurodiverse Young AdultsNot yet recruitingNCT06479850Not applicable
- Poly-unsaturated Fatty Acids and Developmental DyslexiaRecruitingNCT04287530Not applicable1 country
- Neuroplasticity of Multisensory Cortical Areas Induced by Musical Training: a Translational Approach (MusicPlast)RecruitingNCT03786185Not applicable1 country
- Gene x Environment Interplay in Developmental Dyslexia Treatment: A Round-trip Translation Between Humans and AnimalRecruitingNCT06186882Not applicable1 country
- Comparing the Efficacy of tDCS and tRNS to Improve Reading Skills in Children and Adolescents With DyslexiaEnrolling by invitationNCT05832060Not applicable1 country
- V5/MT Stimulation on Reading and Reading-related Measures in Developmental DyslexiaRecruitingNCT05972200Not applicable1 country
- Efficacy of rTMS as an Adjunct to AI Enabled Remedial Intervention in Children With DyslexiaRecruitingNCT05923645Not applicable1 country
- The Role of Knowledge Retrieval in Inference-makingRecruitingNCT05692973Not applicable1 country
- Clinical Effectiveness of iReadMore for People With AlexiaRecruitingNCT048490911 country
- Usefulness of an Assistive Technology Training Program for Adolscents With DyslexiaCompletedNCT05636813Not applicable1 country
- Promoting Caregiver Implementation of an Effective Early Learning InterventionActive, not recruitingNCT06275815Not applicable1 country
- Pai.ACT: AI-Driven ACT Chatbot for Mental Health Triage and Service EvaluationActive, not recruitingNCT06808555Not applicable1 country
- Neurocognitive Factors in EdTech Intervention ResponseCompletedNCT04568824Not applicable1 country
- Noninvasive Brain Stimulation to Enhance Reading Comprehension Ability in AdultsCompletedNCT05523505Not applicable1 country
- Let's Know!2: Language-focused Intervention for Children at Risk of Comprehension DifficultiesActive, not recruitingNCT05133479Not applicable1 country
- Tackling Two of the Most Important Unresolved Tasks in Reading InterventionCompletedNCT06403007Not applicable1 country
- Examining the Medium-term Effect on Non Inferiority of the Previous Training With the DMD Poppins Clinical for Cognitive, Musical Training in Addition to Bi-monthly Speech and Reading Therapy on Reading Writing Abilities of Pediatric Patients With SLD Reading VS Control GroupCompletedNCT069026101 country
- Interventions for Reading Disabilities in NF1Active, not recruitingNCT02964884Phase 21 country
- Dyslexia, Motor Control and ProprioceptionTerminatedNCT03364010Not applicable1 country
- Enhancing Reading Recovery in Aphasia With tDCS and Phonomotor TherapyCompletedNCT06891638Not applicable1 country
- Language Development Deficits and Early Interactive Music InterventionActive, not recruitingNCT06261307Not applicable1 country
- Improving the Academic Performance of First-Grade Students With Reading and Math DifficultyCompletedNCT03991234Not applicable1 country
- Impact of Non-invasive Brain Stimulation on Learning Novel Spoken WordsCompletedNCT06387615Not applicable1 country
- Perinatal and Psychological Correlates of Neurodevelopmental Disorders in Children.CompletedNCT062150921 country
- Examining the Effect of a Digital MD for Cognitive and Musical Training + Reduced Conventional SOC on the Reading and Writing Skills of Pediatric Participants With a Specific Learning Disability With Reading and/or Written Expression Deficit vs a Control Group Receiving Conventional SOC.CompletedNCT06592911Not applicable1 country
- Impact of Motor Tasks and Lidocaine on Reading Unfamiliar Words in Adults With and Without DyslexiaCompletedNCT05854082Phase 41 country
- Characterization of Auditory Processing Involved in the Encoding of Speech SoundsCompletedNCT02574299Not applicable1 country
- Intervention Efficacy of ALD for Children With DyslexiaCompletedNCT07247253Not applicable1 country
- Neural Mechanisms of Successful Intervention in Children With DyslexiaCompletedNCT04323488Not applicable1 country
- Building Long-term Academic Success Through Ongoing Fun Fitness ProgramWithdrawnNCT04113707Not applicable
- Neurobiology and Treatment of Reading Disability in NF-1CompletedNCT00624234Not applicable1 country
- Behavioural and Physiological Measures of Young Students With DyslexiaCompletedNCT05376696Not applicable1 country