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TerminatedNCT03364010Updated May 14, 2026

Dyslexia, Motor Control and Proprioception

An interventional study of Evaluation of proprioception and Evaluation of motor learning in Dyslexia, sponsored by Institut National de la Santé Et de la Recherche Médicale, France. Terminated at 1 site in France. Open to participants aged 10 Years to 12 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-05-14.

Sponsored by Institut National de la Santé Et de la Recherche Médicale, France · Not applicable, Interventional, and Basic science

Why this study was terminated
Suspension due to COVID-19
Phase
Not applicable
Study type
Interventional
Enrollment
56
Allocation
Not applicable
Ages
10 Years to 12 Years
Sex
All
01

Study summary

The investigators hypothesize that children with dyslexia present proprioceptive disorders and the purpose of the present study is to better understand relationships between motor control, proprioception and academic learnings. The investigators compare a group of French students with and without dyslexia aged 10-12.

Read the detailed description

2 groups of children (dyslexics and control) will be evaluated on 2 tasks:

  • Evaluation of the proprioception: Perception of the speed and Perception of the position
  • Evaluation of the motor learning: Estimation of state in the framework of a motor perturbation
02

Conditions studied

  • Dyslexia

Browse trials for

Keywords

  • Motor control
  • Proprioception
03

Who can participate

Ages eligible
10 Years to 12 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Child with a French social security
  • School child
  • Native French speaker
  • right-handed
  • Normal or corrected vision
  • Without neurological or psychiatric histories
  • Agree to participate in the study in agreement with parental rights representatives

For the dyslexic group :

  • pluridisciplinary diagnostic
  • never consulted for proprioception before
  • without any other leaning disorders like dysphasia
  • attention deficit hyperactivity disorder (ADHD) or developmental coordination disorder (DCD)

For the control group :

  • regular school attendance
  • never consulted for learning disabilities
  • No learning disorders known for their parents or siblings.

Exclusion criteria

Exclusion criteria for all children

  • genetic disorder
  • neurological or psychiatric history
  • Delayed psychomotor development
  • Reeducation or current treatment interfering with the evaluation
04

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
56 participants (actual)

Study arms

  • Experimental
    Dyslexic and non dyslexic Children

    Children aged 10-12 Evaluation of proprioception Evaluation of motor learning Evaluation of written language

    Behavioral: Evaluation of proprioception · Behavioral: Evaluation of motor learning · Behavioral: Evaluation of written language

Interventions

  • BehavioralEvaluation of proprioception

    Velocity perception and Position perception

  • BehavioralEvaluation of motor learning

    Motor accurancy and State Estimation with visual perturbations

  • BehavioralEvaluation of written language

    Text reading, Identifying words and Phonological awareness: phonemic blending and phonemic elision

05

What researchers measure

Primary outcomes

  1. Evaluation of proprioception through velocity perception

    The ability to perceive motion at 3 different velocities for 3 different joints is assessed using a motorized ergometer. A passive movement is performed by the ergometer and children are tasked to press a button as soon as they feel the movement. We calculate the angle of detection for each speed and compare it between Dyslexic and healthy children.

    Time frame: 1day

Secondary outcomes

  1. Evaluation of proprioception through position perception

    The ability to perceive position is assessed using an ergometer that produces passive movements of 3 different amplitudes on the dominant arm. In a second time, the ergometer produces a passive movement of the same arm and children are tasked to press a button as soon as they feel they are in the exact previously-experienced position. We calculate the angular error and compare it between Dyslexic and healthy children.

    Time frame: 1 day

  2. Motor learning

    The ability to learn new motor tasks is assessed using virtual reality and motor acquisition systems. First we evaluate the motor accuracy and the state estimation by pointing tests. Then visual perturbations are introduced during pointing. Finally, we evaluate motor accuracy and state estimation again.

    Time frame: 1 day

  3. Text reading

    The ability to read aloud a text is assessed using the French standardized test " Alouette ", which provide accuracy in reading aloud age-normed texts (ratio between words that have been correctly read and all the words that have been read).

    Time frame: 1day

  4. Phonological awareness: phonemic blending and phonemic elision

    The ability to derive a phonemic pattern from distinct phonemic units or to substitute a phonemic pattern for another is assessed using the French standardized test " Nepsy2, phonological process " which provide standard deviation in reading aloud by the investigator.

    Time frame: 1day

  5. Identifying words

    The ability to identify words is assessed using the French standardized test " Timé3 ", which provide lexical level and delay reading in silent reading age-normed words.

    Time frame: 1day

06

Study locations

1 site
  • Inserm U1093
    Dijon, Bourgogne-Franche-Comté 21000, France
07

References and documents

Publications

  • Laprevotte J, Papaxanthis C, Saltarelli S, Quercia P, Gaveau J. Movement detection thresholds reveal proprioceptive impairments in developmental dyslexia. Sci Rep. 2021 Jan 11;11(1):299. doi: 10.1038/s41598-020-79612-4. PubMed 33431949 ↗
08

Registry details

Key details

Study ID
NCT03364010
Lead sponsor
Institut National de la Santé Et de la Recherche Médicale, France
Responsible party
Sponsor
First posted
Dec 6, 2017
Start date
Jan 4, 2018
Primary completion
May 9, 2019
Completion
Jun 2, 2021
Last update
May 14, 2026

Study contacts

Patrick QUERCIA, dr
principal investigator · Unité Inserm d'affiliation : Laboratoire U1093 Cognition, Action et Plasticité Sensorimotrice

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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