Drug
Amantadine clinical trials
Also written Symmetrel and GOCOVRI.
- studies test it
- 71
- open now
- 8
- in phase 3
- 17
- first study started
- 1996
Keep track of what changes. Save the Amantadine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Studies by the year they started
71 studies that test it; most in 2009 (7)
| Year | Studies |
|---|---|
| 1996 | 1 |
| 1997 | 1 |
| 1999 | 2 |
| 2000 | 2 |
| 2001 | 1 |
| 2002 | 1 |
| 2003 | 3 |
| 2004 | 1 |
| 2005 | 3 |
| 2006 | 2 |
| 2007 | 1 |
| 2008 | 2 |
| 2009 | 7 |
| 2010 | 5 |
| 2011 | 4 |
| 2012 | 1 |
| 2014 | 4 |
| 2015 | 1 |
| 2016 | 1 |
| 2017 | 2 |
| 2018 | 2 |
| 2019 | 2 |
| 2020 | 5 |
| 2021 | 4 |
| 2022 | 3 |
| 2023 | 4 |
| 2024 | 2 |
| 2025 | 1 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 5
- Phase 2
- 25
- Phase 3
- 17
- Phase 4
- 15
- No phase
- 12
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 8 · Other 63
Wake Forest University Health Sciences (3) · Adamas Pharmaceuticals, Inc. (3) · University Hospital, Toulouse (2) · Cairo University (2) · Ain Shams University (2) · Oregon Health and Science University (2) · Johns Hopkins University (2) · University of Pennsylvania (2)
Often tested with
Tested in the same studies.
Ribavirin (4) · Oseltamivir (3) · Pregabalin (2) · Propranolol (2) · Peginterferon alfa-2a (2) · Cerebrolysin (1) · Cytidine Diphosphate Choline (1) · Modafinil (1)
Studies
Open first, then newest update. How each study uses Amantadine is read from its arms, and is right about nine times in ten.
Testing it · 71
- Evaluation of the Effect of Amantadine in the Prevention of Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer PatientsNot yet recruitingPhase 2Al-Azhar UniversityNCT07889115Written as Amantadine (oral)
- Use of Gocovri to Improve Disability Due to Radiation EncephalopathyNot yet recruitingPhase 2Weill Medical College of Cornell UniversityNCT07125222Written as Gocovri (extended-release amantidine)
- Promoting Recovery After STroke With AmantadineRecruitingPhase 2University of PennsylvaniaNCT05140148Written as Amantadine
- Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised TrialRecruitingPhase 2/3University of EdinburghNCT04302870Written as Amantadine Hydrochloride Oral Solution
- Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain SyndromeRecruitingNot applicableCairo UniversityNCT07421427Written as Pregabalin + Amantadine
- Amantadine for Neuroenhancement in Acute Patients StudyRecruitingPhase 2University Hospital TuebingenNCT05479032Written as Amantadine
- Amantadine and Transcranial Magnetic Stimulation for Treating Fatigue in Multiple SclerosisRecruitingPhase 3Hospital San Carlos, MadridNCT05809414Written as Amantadine Hydrochloride 100 mg (milligrams) Oral Capsule
- Comparison of Antidepressant Augmentation With Amantadine vs Pramipexole vs Quetiapine in Treatment Resistant DepressionRecruitingPhase 4All India Institute of Medical Sciences, BhubaneswarNCT04936126Written as Amantadine
- Amantadine and L-DOPA-induced Dyskinesia in Early Parkinson's DiseaseCompletedPhase 2University Hospital, ToulouseNCT01538329Written as Amantadine
- Amantadine Therapy for Cognitive Impairment in Long COVIDCompletedPhase 2Ohio State UniversityNCT06055244Written as Amantadine
- Adding Amantadine to Pregabalin on Occurrence of Post-thoracotomy Pain SyndromeCompletedNot applicableCairo UniversityNCT06833203Written as Amantadine+ Pregabalin
- Combined Cerebrolysin and Amantadine Sulfate Administration for Patients With Traumatic Brain Injury in the ICUCompletedPhase 3Ain Shams UniversityNCT06052787Written as amantadine sulfate
- A Study of Amantadine for Cognitive Dysfunction in Patients With Long-CovidWithdrawnPhase 2University of Texas Southwestern Medical CenterNCT06234462Written as Amantadine
- A Study Comparing Propranolol and Amantadine for Reducing Tremors in People With Parkinson's DiseaseCompletedNot applicableMultan Medical And Dental CollegeNCT07113015Written as Amantadine
- Study to Assess the Safety of Amantadine Hydrochloride (HCl) Intravenous (IV) Solution (MR-301) in Patients With Severe Traumatic Brain Injury (TBI).Active, not recruitingPhase 2SHINKEI Therapeutics, IncNCT06253923Written as Amantadine Hydrochloride
- Effect of GOCOVRI (Amantadine, Extended Release Capsules) on Gait in Parkinson's DiseaseCompletedPhase 4Oregon Health and Science UniversityNCT04387773Written as GOCOVRI
- Effect of Intravenous Amantadine Sulphate on Disorders of ConsciousnessActive, not recruitingPhase 2Azienda Sanitaria dell'Alto AdigeNCT06443827Written as Amantadine Sulfate
- Citicholine-Amantadine Trial in Traumatic Brain InjuryCompletedPhase 4Ain Shams UniversityNCT03430817Written as Amantadine
- Amantadine for Treatment of Symptoms of the Post-traumatic Confusional StateCompletedPhase 4Methodist Rehabilitation CenterNCT00693121Written as Amantadine hydrochloride
- Impact of Amantadine on Traumatic Brain InjuryCompletedPhase 4Damanhour UniversityNCT04527289Written as Amantadine (100mg) as add on therapy.
See all 71 studies that test Amantadine →
Given in every arm · 1 — Amantadine is usual care beside what is tested
As the comparator · 1 — what is tested is compared with Amantadine
Codes
What other systems call Amantadine · ClinicalTrials.gg INT006936
- MeSH (NLM) D000547AmantadineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) BF4C9Z1J53AMANTADINEConfirmed FDA, NLM, Wikidata
- RxNorm 620Confirmed FDA, Wikidata
- Wikidata Q409761amantadineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C61632AmantadineOne source FDA
- DrugBank DB00915One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000547 | Amantadine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | BF4C9Z1J53 | AMANTADINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 620 | — | Confirmed FDA, Wikidata |
| Wikidata | Q409761 | amantadine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C61632 | Amantadine | One source FDA |
| DrugBank | DB00915 | — | One source Wikidata |
Also registered as amantadine hydrochloride (UNII M6Q1EO9TD0 · RxNorm 282415) and amantadine sulfate (UNII 9921T5P019 · RxNorm 621).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.