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Huntington Disease clinical trials

The registry lists 293 studies for Huntington Disease across more than 10 countries. 54 are recruiting or about to start. 245 of them are mainly about Huntington Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.

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Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

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Status

Completed
161
Recruiting
43
Status unknown
31
Terminated
25
Active, not recruiting
19
Not yet recruiting
9

Phase

Phase 2
76
Phase 1
57
Phase 3
29
Early Phase 1
6
Phase 4
4

Where

United States
138
France
63
Canada
52
United Kingdom
51
Germany
44
Spain
29

Who runs them

Assistance Publique - Hôpitaux de Paris (12) · Pfizer (12) · CHDI Foundation, Inc. (11) · Massachusetts General Hospital (8) · University Hospital, Angers (8) · Institut National de la Santé Et de la Recherche Médicale, France (7) · Hoffmann-La Roche (7) · Prilenia (6)

What is being tested here

Drugs under test in Huntington Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Pridopidine138
Creatine117
Creatine monohydrate116
LPM3770164104
Votoplam113
Valbenazine133
Beta-hydroxyisovaleric acid101
Nicotinamide-beta-riboside101
Acetylcysteine101
Latrepirdine0213

Drug classes tested here Antipsychotics 3

Coming up

8phase 3 studies under way
21studies finish main data collection within a year2 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 43 Huntington Disease studies recruiting now, 19 (44%) set no upper age limit and 20 (47%) stop at 75 or younger. 5 (12%) take children under 18. 2 (5%) are for women only and 0 (0%) for men only; 20 (47%) take healthy volunteers.

Recruiting studies that take each age, of 43
AgeWomenMen
104 (9%)4 (9%)
1831 (72%)29 (67%)
3043 (100%)41 (95%)
4043 (100%)41 (95%)
5043 (100%)41 (95%)
6541 (95%)39 (91%)
7529 (67%)27 (63%)
8521 (49%)19 (44%)

Across all 293 studies, recruiting or not: 38% stop at 75 or younger and 25% at 65; 11% take children; 1% are for women only and 2% for men only; 32% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Huntington Disease studies take

Of 22 phase 2 interventional studies under Huntington Disease, half reached primary completion within 31 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 121 mo7–29 · 19 studies——
Phase 231 mo21–40 · 22 studies——
Interventional, no phase32 mo19–36 · 33 studies——
Observational47 mo34–… · 34 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 15, 2026.

Stopped1

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 50 of 293. Browse all 293 → or search them.