Autoimmune Diseases clinical trials
The registry lists 802 studies for Autoimmune Diseases across more than 10 countries. 271 are recruiting or about to start. 219 of them are mainly about Autoimmune Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 41 narrower conditions too, such as Diabetes Mellitus, Type 1: 15,730 studies, 3,333 open.
ClinicalTrials.gov finds 15,606 studies for Autoimmune Diseases. How that becomes 802 here
This page counts the studies the registry files under Autoimmune Diseases, and those it files under no condition that list Autoimmune Diseasesthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 15,606Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −14,438Filed under a narrower condition, counted on its own pageDiabetes Mellitus, Type 1 3,509 · Arthritis, Rheumatoid 3,201 · Multiple Sclerosis 3,078 · Lupus Erythematosus, Systemic 956 · Purpura, Thrombocytopenic, Idiopathic 450 · Arthritis, Juvenile 311 · 34 more
- −13List Autoimmune Diseases as a condition, but the registry did not file them under itMost often written as “Systemic Autoimmune Diseases” (4), “Raynaud's Disease Secondary to Autoimmune Disease” (1), and “Raynaud's Disease Secondary to Other Autoimmune Disease” (1). The registry filed them under other conditions only, most often Raynaud Disease (2) and Scleroderma, Diffuse (2).
- −353Match it another way32 name it in the title, 7 in a keyword, and 314 by a synonym or other text the search reads.
- 802The count on this page14 of them list Autoimmune Diseases in their own words; the registry filed them under no condition.
Get an email when these change. Save the Autoimmune Diseases studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
National Institute of Allergy and Infectious Diseases (NIAID) (22) · GlaxoSmithKline (18) · Assistance Publique - Hôpitaux de Paris (17) · National Heart, Lung, and Blood Institute (NHLBI) (13) · Peking Union Medical College Hospital (11) · Novartis Pharmaceuticals (11) · National Cancer Institute (NCI) (10) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (8)
What is being tested here
Drugs under test in Autoimmune Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Antimetabolites 6 open · Alkylating agents 3 open · Corticosteroids 2 open · Calcineurin inhibitors 2 open · GLP-1 receptor agonists 2 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026A Study Investigating Intravenous Human Normal Immunoglobulin 10% in Adults With Chronic Immune Thrombocytopenia (ITP) · Phase 3 · Kedrion S.p.A.
- Dec 2026A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus · Phase 3 · Viatris Innovation GmbH
- Jan 2027Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY) · Phase 3 · AstraZeneca
- Mar 2027A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus · Phase 3 · Viatris Innovation GmbH
- Jul 2027The Effect of Nicorandil on Rheumatoid Arthritis Patients · Phase 3 · Ain Shams University
- Sep 2027A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections · Phase 3 · X4 Pharmaceuticals
- Sep 2027KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis · Phase 3 · Kyverna Therapeutics
- Nov 2026Study of Single Doses of SBT777101 in Subjects With Hidradenitis Suppurativa · Sonoma Biotherapeutics, Inc.
- Nov 2026Study of Single Doses of SBT777101 in Subjects With Rheumatoid Arthritis · Sonoma Biotherapeutics, Inc.
- Nov 2026Clinical Study of EVM18001 in the Treatment of Refractory Autoimmune Diseases · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Who these studies take
Of the 194 Autoimmune Diseases studies recruiting now, 89 (46%) set no upper age limit and 79 (41%) stop at 75 or younger. 55 (28%) take children under 18. 6 (3%) are for women only and 5 (3%) for men only; 36 (19%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 44 (23%) | 44 (23%) |
| 18 | 179 (92%) | 177 (91%) |
| 30 | 180 (93%) | 178 (92%) |
| 40 | 180 (93%) | 179 (92%) |
| 50 | 179 (92%) | 180 (93%) |
| 65 | 171 (88%) | 172 (89%) |
| 75 | 126 (65%) | 127 (65%) |
| 85 | 107 (55%) | 107 (55%) |
Across all 802 studies, recruiting or not: 46% stop at 75 or younger and 31% at 65; 25% take children; 5% are for women only and 2% for men only; 21% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Autoimmune Diseases studies take
Of 94 phase 1 interventional studies under Autoimmune Diseases, half reached primary completion within 23 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 23 mo9–36 · 94 studies | 12 mo9–32 · 68 studies | — |
| Phase 2 | 55 mo34–100 · 60 studies | — | 76 mo52–114 · 31 studies |
| Phase 3 | 48 mo36–84 · 29 studies | — | — |
| Interventional, no phase | 31 mo15–62 · 86 studies | — | 31 mo16–62 · 77 studies |
| Observational | 121 mo41–309 · 92 studies | — | 121 mo41–309 · 77 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting6
- Study of PTC844 in Participants With Active Rheumatoid ArthritisNov 6, 2026NCT07779616
- A Phase 3 Blinded Study of JADE101 in Participants With Immunoglobulin A NephropathyNov 3, 2026NCT07902817
- Tissue Modeling in Systemic Sclerosis Using Induced Pluripotent Stem Cells (iPSCs)Oct 29, 2026NCT07650565
- A Study of ATG-201 in Adult Participants With Autoimmune DiseasesOct 28, 2026NCT07732309
- A Study to Test CRT-402 in Refractory Autoimmune DiseaseOct 22, 2026NCT07778446
Show 1 moreShow fewer
Results posted1
- Day and Night Closed-loop in Young People With Type 1 DiabetesOct 15, 2026NCT02925299
Stopped5
- A Study of CAR-T Cells Targeting Autoimmune DiseasesWithdrawnOct 15, 2026NCT06661811
- Safety and Efficacy of CD19 CAR-T Therapy for Recurrent/Refractory Autoimmune DiseasesWithdrawnOct 15, 2026NCT06983964
- Autologous CD19CAR-T Therapy for Recurrent/Refractory Autoimmune DiseasesWithdrawnOct 15, 2026NCT06993493
- A Clinical Study of AFN50 in the Treatment of Autoimmune DiseasesWithdrawnOct 15, 2026NCT07448298
- FIT-(BCMA+CD19)-CAR-T Cells in Recurrent/Refractory Autoimmune Diseases Patients.WithdrawnOct 15, 2026NCT07604792
Newly registered5
- A Phase 1 Study of QLS2416 Injection in Participants With Autoimmune DiseasesOct 30, 2026NCT07906145
- A Clinical Study to Evaluate the Safety and Effectiveness of MSCohi-O Lens in the Treatment of Immune-related Ocular Surface Diseases.Oct 29, 2026NCT07902687
- A Phase 3 Blinded Study of JADE101 in Participants With Immunoglobulin A NephropathyOct 29, 2026NCT07902817
- Evaluation of ETHY-001 for Safety, Tolerability, and Clinical Activity in Thyroid Eye DiseaseOct 21, 2026NCT07885605
- A Study of BMS-986553 in Participants With Refractory Autoimmune DiseasesOct 14, 2026NCT07873931
Studies
Recruiting first, then most recently updated. Showing 50 of 802. Browse all 802 → or search them.
- Deciphering the Genetic Architecture of Autoimmune DiseasesRecruitingNCT069481102 countries
- Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of ImmunityRecruitingNCT04339777Phase 21 country
- Two Arm, Double-blind, Phase III Study Assessing Efficacy and Safety of Ianalumab Versus Placebo, in Participants With Sjögren's Disease With High Symptom BurdenRecruitingNCT07621809Phase 320 countries
- Secukinumab Open Label Roll-over Extension ProtocolRecruitingNCT04638647Phase 422 countries
- Safety of Belimumab in People With Idiopathic CD4 Lymphopenia and Autoantibodies (Phoebe)RecruitingNCT04097561Phase 11 country
- Natural History of BronchiectasisRecruitingNCT009435141 country
- Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ LymphocytopeniaRecruitingNCT008672691 country
- Study of PTC844 in Participants With Active Rheumatoid ArthritisRecruitingNCT07779616Phase 24 countries
- Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesRecruitingNCT02579967Phase 21 country
- A Trial in Healthy Adult Participants and Adults With Autoimmune Diseases to Test How HBM7020 is Tolerated and How it Behaves in the BodyRecruitingNCT07649265Phase 11 country
- A Study of Mezagitamab in Adults With Chronic Primary Immune ThrombocytopeniaRecruitingNCT06722235Phase 318 countries
- Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune DisordersRecruitingNCT06434363Phase 1/21 country
- A Phase 3 Blinded Study of JADE101 in Participants With Immunoglobulin A NephropathyRecruitingNCT07902817Phase 31 country
- CAR-T Cells Targeting Autoimmune DiseasesNot yet recruitingNCT05459870Phase 1/21 country
- NIAID Centralized Sequencing ProtocolRecruitingNCT032060991 country
- A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune DiseaseRecruitingNCT07085104Phase 12 countries
- Autoimmune Disease Treatment With Mesenchymal Stem Cells (MSCs) and CAR-T CellsNot yet recruitingNCT06435897Phase 1/21 country
- A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune ThrombocytopeniaRecruitingNCT06948318Phase 315 countries
- A Phase 1 Study of QLS2416 Injection in Participants With Autoimmune DiseasesNot yet recruitingNCT07906145Phase 1
- A Study of JADE101 in Participants With Immunoglobulin A NephropathyRecruitingNCT07541287Phase 25 countries
- Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell DeathRecruitingNCT002468572 countries
- Tissue Modeling in Systemic Sclerosis Using Induced Pluripotent Stem Cells (iPSCs)RecruitingNCT07650565Not applicable1 country
- A Clinical Study to Evaluate the Safety and Effectiveness of MSCohi-O Lens in the Treatment of Immune-related Ocular Surface Diseases.Not yet recruitingNCT07902687Phase 1
- CD19-Directed CAR-T Cell Therapy in Refractory Systemic Lupus ErythematosusNot yet recruitingNCT07659704Phase 1/21 country
- A Study of ATG-201 in Adult Participants With Autoimmune DiseasesRecruitingNCT07732309Phase 11 country
- Evaluation of ETHY-001 for Safety, Tolerability, and Clinical Activity in Thyroid Eye DiseaseRecruitingNCT07885605Phase 11 country
- Rituximab Plus Cyclosporine in Idiopathic Membranous NephropathyRecruitingNCT00977977Phase 21 country
- A Study Investigating Intravenous Human Normal Immune Globulin 10% in Adults With Stiff Person SyndromeNot yet recruitingNCT07552987Phase 3
- A Study to Test CRT-402 in Refractory Autoimmune DiseaseRecruitingNCT07778446Phase 1/21 country
- Study of Anitocabtagene Autoleucel in Participants With Non-Oncology Plasma Cell-Related DiseasesRecruitingNCT06626919Phase 11 country
- A Study Investigating Intravenous Human Normal Immunoglobulin 10% in Adults With Chronic Immune Thrombocytopenia (ITP)RecruitingNCT07059000Phase 38 countries
- Testimonials and Navigation in RheumatologyRecruitingNCT06469788Not applicable1 country
- A Clinical Study of YTS109 Cells for the Treatment of R/R Autoimmune DiseasesRecruitingNCT07123519Phase 11 country
- A Clinical Study of YTS109 Cell for R/R Autoimmune DiseasesRecruitingNCT07104721Phase 11 country
- Daratumumab in Primary Antiphospholipid SyndromeRecruitingNCT05671757Phase 1/21 country
- RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia GravisRecruitingNCT06359041Phase 1/21 country
- A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) SyndromeRecruitingNCT05027945Phase 21 country
- Environmental Risk Factors for the Anti-synthetase SyndromeRecruitingNCT012764701 country
- RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic SclerosisRecruitingNCT06328777Phase 2/31 country
- Hyaluronidase for Sclerodactyly in Systemic Sclerosis TrialNot yet recruitingNCT07697274Early Phase 11 country
- RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory MyopathyRecruitingNCT06154252Phase 2/34 countries
- A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)RecruitingNCT04422912Phase 1/21 country
- A Study of Safety, Tolerability, PK, and PD of Subcutaneous GenSci136 in Healthy Adults.RecruitingNCT07366866Phase 11 country
- A Study of BMS-986553 in Participants With Refractory Autoimmune DiseasesNot yet recruitingNCT07873931Phase 16 countries
- C-CAR168, an Autologous Anti-CD20/BCMA Chimeric Antigen Receptor T-Cell Therapy, in Participants With Systemic Sclerosis (SSc) Refractory to Standard TherapyNot yet recruitingNCT07854483Phase 11 country
- First in Human Study of ALT-01 in Healthy ParticipantsNot yet recruitingNCT07865442Phase 11 country
- C-CAR168, an Autologous Anti-CD20/BCMA Chimeric Antigen Receptor T-Cell Therapy, in Participants With Lupus Nephritis Refractory to Standard TherapyNot yet recruitingNCT07729826Phase 2
- The diabEAT Study: Insulin dElivery Technologies And eaTing Behaviours in People With Type 1 DiabetesRecruitingNCT073484321 country
- Study of Autoimmune Lymphoproliferative Syndrome (ALPS)RecruitingNCT000013501 country
- Exploratory Study of the Efficacy of HuMoSCs (Human Monocyte-derived Suppressor Cells) on Glandular Involvement in Sjögren's SyndromeNot yet recruitingNCT07861828Not applicable1 country