Amgen: Arthritis, Rheumatoid trials

The registry lists 59 Arthritis, Rheumatoid studies with Amgen as lead sponsor. 1 are open to participants now and 31 have results posted.

Phase 1 9Phase 2 18Phase 3 18Phase 4 12No phase 6(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune DiseasesRecruitingNCT06570798Phase 2
• A Study to Evaluate the Safety and Efficacy of VIB4920 in Participants With Rheumatoid ArthritisCompletedNCT04163991Phase 2Results posted
• Etanercept Plus Methotrexate Versus Methotrexate Alone in Children With Polyarticular Course Juvenile Rheumatoid ArthritisTerminatedNCT03781375Phase 3Results posted
• Safety and Efficacy of Etanercept (Recombinant Human Tumor Necrosis Factor Receptor Fusion Protein [TNFR:Fc]) in Children With Juvenile Rheumatoid Arthritis (JRA)CompletedNCT03780959Phase 2/3Results posted
• Safety and Efficacy of Efavaleukin Alfa in Subjects With Active Rheumatoid ArthritisTerminatedNCT03410056Phase 1/2Results posted
• Multiple Ascending Doses of Rozibafusp Alfa (AMG 570) in Adults With Rheumatoid ArthritisCompletedNCT03156023Phase 1Results posted
• Study to Assess the Injection Site Pain Associated With a New Etanercept Formulation in Adults With Rheumatoid Arthritis or Psoriatic ArthritisCompletedNCT02986139Phase 3Results posted
• Study to Assess if ABP710 is Safe & Effective in Treating Moderate to Severe Rheumatoid Arthritis Compared to InfliximabCompletedNCT02937701Phase 3Results posted
• Study to Assess if ABP 798 is Safe & Effective in Treating Moderate to Severe Rheumatoid Arthritis (RA) Compared to RituximabCompletedNCT02792699Phase 3Results posted
• A Phase 1b Study of MEDI4920 in Participants With Adult-onset Rheumatoid ArthritisCompletedNCT02780388Phase 1Results posted
• Study of Etanercept Monotherapy vs Methotrexate Monotherapy for Maintenance of Rheumatoid Arthritis RemissionCompletedNCT02373813Phase 3Results posted
• Evaluate Effects of Personalized Patient Counselling for Enbrel® Therapy in Adults With Rheumatoid ArthritisTerminatedNCT02346877Phase 4Results posted
• A Non-Interventional Study of RAYOS in Adult Patients With Rheumatoid ArthritisCompletedNCT02287610Results posted
• Long-term Safety and Efficacy of ABP 501 in Subjects With Moderate to Severe Rheumatoid ArthritisCompletedNCT02114931Phase 3Results posted
• Efficacy and Safety Study of ABP 501 Compared to Adalimumab in Subjects With Moderate to Severe Rheumatoid ArthritisCompletedNCT01970475Phase 3Results posted
• Evaluating Etanercept Use in Patients With Moderate to Severe Rheumatoid Arthritis Who Have Lost Response to AdalimumabTerminatedNCT01927757Phase 4Results posted
• Study to Evaluate the Ability of Subjects With Rheumatoid Arthritis or Psoriatic Arthritis to Effectively Use a Reusable Autoinjector to Self-inject EtanerceptCompletedNCT01901185Phase 3Results posted
• Preference Between Two Autoinjectors in Patients With Rheumatoid Arthritis and Plaque Psoriasis Treated With EtanerceptCompletedNCT01875991Phase 4Results posted
• Moderate Rheumatoid Arthritis (RA) With Etanercept (Enbrel)CompletedNCT01313208Phase 4Results posted
• Effects of Denosumab on the Pharmacokinetics of EtanerceptTerminatedNCT01294397Phase 1Results posted
• Study of Apremilast to Evaluate the Safety and Effectiveness for Patients With Rheumatoid ArthritisTerminatedNCT01285310Phase 2Results posted
• Safety and Efficacy of AMG 827 in Subjects With RATerminatedNCT01059448Phase 2Results posted
• Safety Study of HZT-501 in Patients Who Require Long-Term Daily Non-steroidal Anti-inflammatory Drug TreatmentCompletedNCT00984815Phase 3Results posted
• Brodalumab (AMG 827) in Rheumatoid Arthritis (RA) Participants With Inadequate Response to MethotrexateCompletedNCT00950989Phase 2Results posted
• Study to Evaluate the Safety, PK, PD and Efficacy of AMG 827 in Adults With Rheumatoid ArthritisCompletedNCT00771030Phase 1/2Results posted
• CAMEO: Canadian Methotrexate and Etanercept Outcome StudyCompletedNCT00654368Phase 4Results posted
• Study to Assess the Safety and Efficacy of Modified-Release Prednisone (Lodotra®) Therapy in Patients With Active Rheumatoid ArthritisCompletedNCT00650078Phase 3Results posted
• Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Measure Response to Etanercept in Rheumatoid ArthritisCompletedNCT00361634Phase 1Results posted
• Open-Label Extension Treatment With Etanercept (TNFR:Fc) for Participating Patients in Etanercept (TNFR:Fc) Clinical TrialsCompletedNCT00357903Phase 3Results posted
• Open-Label Extension Treatment With Etanercept (TNFR:Fc) for Participating Patients in Etanercept (TNFR:Fc) Clinical Trial 016.0012CompletedNCT00356590Phase 3Results posted
• Efficacy, Safety and Tolerability of Denosumab in the Treatment of Rheumatoid ArthritisCompletedNCT00095498Phase 2Results posted
• Safety and Efficacy Study of Etanercept (Enbrel®) In Children With Systemic Onset Juvenile Rheumatoid ArthritisTerminatedNCT00078806Phase 3Results posted
• Study to Evaluate the Safety, Tolerability, and Action of AMG 357 in Females With Rheumatoid ArthritisTerminatedNCT02499315Phase 1
• Phase 1 Single and Multiple Dose Study of FPA008 in Healthy Volunteers and Rheumatoid Arthritis SubjectsTerminatedNCT01962337Phase 1
• A Study to Evaluate the Safety and Efficacy of CCX354-C in Subjects With Rheumatoid Arthritis Partially Responsive to Methotrexate TherapyCompletedNCT01242917Phase 2
• Study to Evaluate Safety and Efficacy of CCX 354-C in Subjects With Rheumatoid ArthritisCompletedNCT01027728Phase 1/2
• The SPECTRA StudyTerminatedNCT00537667Phase 2
• Ancillary Study to Protocol 20060104CompletedNCT00439894
• Phase 2 AMG 714 in Rheumatoid ArthritisCompletedNCT00433875Phase 2
• Etanercept SFP in RA PatientsCompletedNCT00413452Phase 3
• Long-Term Assessment of Safety and Physical Function With AMG 108 in RACompletedNCT00369473Phase 2
• An Open-Label Study to Assess the Rate of Failure of an Enbrel® (Etanercept) SureClick™ Auto-injector in Subjects With Rheumatoid ArthritisCompletedNCT00346294Phase 4
• A Multiple Dose Study to Evaluate Subcutaneous AMG 108 in Subjects With Rheumatoid ArthritisCompletedNCT00293826Phase 2
• Enbrel Liquid Immunogenicity ProtocolCompletedNCT00249041Phase 3
• Study of Enbrel in Rheumatoid Arthritis (RA) Subjects With Comorbid DisordersCompletedNCT00132418Phase 4
• REKinDLE: Registry With Enbrel® or Kineret® in a Database Using Longitudinal EvaluationsCompletedNCT00121056
• Evaluating Kineret® (Anakinra) in Rheumatoid Arthritis (RA) Subjects Using aSelf-Reported QuestionnaireCompletedNCT00121043Phase 4
• Anakinra (Kineret®) in Combination With Disease Modifying Anti-Rheumatic Drugs (DMARDS) in Subjects With Active Rheumatoid Arthritis (RA)CompletedNCT00117091Phase 3
• Rheumatoid Arthritis DMARD Intervention and UtilizationStudyCompletedNCT00116727
• Rheumatoid Arthritis (DMARD) Intervention and UtilizationStudyCompletedNCT00116714
• Evaluating Efficacy and Safety of Etanercept 50 mg Twice Weekly (BIW) in Rheumatoid Arthritis (RA) Subjects Who Are Sub-Optimal Responders to Etanercept 50 mg Once Weekly (QW)CompletedNCT00115219Phase 4
• Evaluating the Safety of Extended Treatment With Pegsunercept (PEG sTNF-RI)in Subjects With Rheumatoid Arthritis (RA)CompletedNCT00111423Phase 2
• Evaluating the Effect of Anakinra (r-metHuIL-1ra) on Vaccine AntibodyResponse in Subjects With Rheumatoid Arthritis (RA)CompletedNCT00111410Phase 4
• Treatment for Subjects With Active Rheumatoid Arthritis (RA)CompletedNCT00110903Phase 3
• Effectiveness and Safety of Enbrel® (Etanercept) in Rheumatoid Arthritis Subjects Who Have Failed Remicade® (Infliximab)CompletedNCT00099554Phase 4
• Preference of Rheumatoid Arthritis (RA) Patients of Enbrel® (Etanercept) Auto-Injector Versus Enbrel® Pre-Filled SyringesCompletedNCT00094341Phase 4
• Registry of Etanercept (Enbrel®) In Children With Juvenile Rheumatoid ArthritisCompletedNCT00078793
• A Rheumatoid Arthritis (RA) Study Treating Signs and Symptoms of RA in People With RA & Receiving MethotrexateCompletedNCT00038298Phase 2
• Evaluation of the Efficacy of Combination Treatment With Anakinra and Pegsunercept in Improving Rheumatoid ArthritisCompletedNCT00037700Phase 2