Still's Disease, Adult-Onset clinical trials
The registry lists 23 studies for Still's Disease, Adult-Onset across more than 10 countries. 5 are recruiting or about to start. 14 of them are mainly about Still's Disease, Adult-Onset (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Who runs them
Swedish Orphan Biovitrum (6) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (2) · Central Hospital, Nancy, France (2) · Novartis Pharmaceuticals (2) · University of Helsinki (1) · Brugmann University Hospital (1) · Apollo Therapeutics Ltd (1) · Syneos Health (1)
Who develops what
Save this setEvery programme with a company-led study here in the last two years, whatever its size: 1 programme from 1 company, 1 with this as their studies’ main aim; 1 with a live phase 3 study; 0 primary completions in the next 12 months.
Comparator & background therapies
What other companies’ phase 2+ studies give as the comparator or the background here (its leading trial sponsor and partners left out): a sign of what new drugs are measured against, not by itself the standard of care, its prescriptions or its market.
None given by two companies or more yet.
Programmes
“Meets, by arms” reads each study’s arms: vs its arm against the therapy’s; + X vs a combination against it; added to it plus the therapy against the therapy; studied with given together only. The next primary completion is the next phase-3 study’s when there is one.
The 1 programme — sign in to see the whole list, free: filter by phase and aim, sort by late development, direct comparisons or the next primary completion.
Primary completion in the next 12 months (0)
Live phase 2 and 3 studies of these programmes. Primary completion is when the main measure’s data collection ends, as the registry states it (most are estimates); results come later, if they are announced.
None in the next 12 months.
Read from ClinicalTrials.gov, industry-led studies. Main aim: this is the study’s judged main condition; named, not the main aim: the sponsor names it, the study is about something else; registry mapping only: only the registry’s mapping put it here. Leading trial sponsor is the company leading the most industry studies of a drug, a measure of trial activity, not of rights. US and EU rights, and Approved: from the regulators’ records (FDA’s Drugs@FDA via openFDA; EMA’s medicines data) — the holder of a marketed or authorised original, generics and other companies’ versions; not rights elsewhere, nor approval for this condition. Phase 4 trial recorded, where neither lists it: a phase 4 study exists somewhere. Not read yet: labels by indication, exclusivity, licences, line of therapy, academic comparators, sales.
What is being tested here
Drugs under test in Still's Disease, Adult-Onset studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Dec 2026A Study on the Use of Canakinumab Among Familial Mediterranean Fever and Still's Disease Patients · Novartis Pharmaceuticals
- Jul 2027Acostill ( RaDiCo Cohort) (RaDiCo Acostill) · Institut National de la Santé Et de la Recherche Médicale, France
Who these studies take
Of the 5 Still's Disease, Adult-Onset studies recruiting now, 2 (40%) set no upper age limit and 0 (0%) stop at 75 or younger. 4 (80%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (40%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (80%) | 4 (80%) |
| 18 | 5 (100%) | 5 (100%) |
| 30 | 5 (100%) | 5 (100%) |
| 40 | 5 (100%) | 5 (100%) |
| 50 | 5 (100%) | 5 (100%) |
| 65 | 5 (100%) | 5 (100%) |
| 75 | 5 (100%) | 5 (100%) |
| 85 | 5 (100%) | 5 (100%) |
Across all 23 studies, recruiting or not: 17% stop at 75 or younger and 9% at 65; 48% take children; 0% are for women only and 0% for men only; 17% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 23 of 23. search them.
- Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related ConditionsRecruitingNCT035104421 country
- A Study on the Use of Canakinumab Among Familial Mediterranean Fever and Still's Disease PatientsRecruitingNCT075172501 country
- Rheumatology Patient Registry and BiorepositoryRecruitingNCT044020861 country
- Acostill ( RaDiCo Cohort) (RaDiCo Acostill)RecruitingNCT059274541 country
- Glycosylated Ferritin in Macrophagic Activation SyndromesRecruitingNCT021439861 country
- Assessment of Macrophage Activation syndromE in STill's DiseaseCompletedNCT064051527 countries
- Therapeutic Value of Sirolimus in Refractory Adult-Onset Still's DiseaseActive, not recruitingNCT07151157Not applicable1 country
- An Efficacy and Safety Study of Subcutaneous Anakinra in Chinese Patients With Systemic Juvenile Idiopathic Arthritis (SJIA) and Adult-Onset Still's Disease (AOSD)WithdrawnNCT07706868Phase 4
- Study of Efficacy and Safety of Canakinumab in Japanese Patients With AOSDCompletedNCT04717635Phase 31 country
- Assessment of Macrophage Activation syndromE in STill's Disease in ItalyCompletedNCT069925051 country
- A Study of Anakinra in Japanese Patients With Still's Disease (SJIA and AOSD)Active, not recruitingNCT05814159Phase 31 country
- Efficacy and Safety Clinical Study of RPH-104 in Adult Onset Still's Disease (AOSD)WithdrawnNCT05432960Phase 31 country
- Assessment of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of APB-R3CompletedNCT05715736Phase 11 country
- A Study to Evaluate Camoteskimab in Participants With Still's DiseaseTerminatedNCT04752371Phase 14 countries
- A Study to Investigate the Safety and Efficacy of Emapalumab, an Anti-IFN-gamma mAb in Patients With Systemic Juvenile Idiopathic Arthritis (sJIA) or Adult-onset Still's Disease (AOSD) Developing Macrophage Activation Syndrome/Secondary HLH (MAS/sHLH)CompletedNCT03311854Phase 25 countries
- A Study to Evaluate Efficacy and Safety of Anakinra in the Treatment of Still's Disease (SJIA and AOSD)TerminatedNCT03265132Phase 32 countries
- Evaluation of Adult Onset Still Disease Classification Criteria and Differential Diagnosis at Eighteen Months of Follow-upCompletedNCT04750863
- Multi-center Registration Study of Adult Onset Still's Disease in Chinese PopulationStatus unknownNCT036511931 country
- Canakinumab for Treatment of Adult-onset Still's DiseaseTerminatedNCT02204293Phase 21 country
- Admission of Adult-onset Still Disease Patients in the ICUCompletedNCT032766501 country
- Treatment of Refractory Adult-onset Still's Disease With Anakinra: a Randomized StudyCompletedNCT01033656Phase 21 country
- Therapeutic Use of Tadekinig Alfa in Adult-onset Still's DiseaseCompletedNCT02398435Phase 23 countries
- Interleukin-1 Trap to Treat Autoinflammatory DiseasesCompletedNCT00094900Phase 21 country