Drug
Tofacitinib clinical trials
Also written CP-690,550 and Xeljanz.
- studies test it
- 184
- open now
- 41
- in phase 3
- 42
- first study started
- 2002
Keep track of what changes. Save the tofacitinib studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
184 studies that test it; most in 2020 (16)
| Year | Studies |
|---|---|
| 2002 | 1 |
| 2003 | 3 |
| 2005 | 4 |
| 2007 | 7 |
| 2008 | 8 |
| 2009 | 7 |
| 2010 | 12 |
| 2011 | 7 |
| 2012 | 8 |
| 2013 | 8 |
| 2014 | 7 |
| 2015 | 3 |
| 2016 | 4 |
| 2017 | 7 |
| 2018 | 6 |
| 2019 | 11 |
| 2020 | 16 |
| 2021 | 11 |
| 2022 | 12 |
| 2023 | 12 |
| 2024 | 9 |
| 2025 | 10 |
| 2026 | 11 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 6
- Phase 1
- 35
- Phase 2
- 70
- Phase 3
- 42
- Phase 4
- 31
- No phase
- 10
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 87 · Other 97
Pfizer (81) · Shanghai Zhongshan Hospital (6) · Second Affiliated Hospital, School of Medicine, Zhejiang University (5) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (4) · Peking University People's Hospital (3) · University of Colorado, Denver (3) · Yale University (3) · Stanford University (2)
Often tested with
Tested in the same studies.
Methotrexate (11) · Etanercept (8) · Tocilizumab (6) · Upadacitinib (5) · Abatacept (5) · Adalimumab (5) · Infliximab (5) · Azathioprine (4)
Studies
Open first, then newest update. How each study uses tofacitinib is read from its arms, and is right about nine times in ten.
Testing it · 184
- Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic ArthritisRecruitingPhase 3Duke UniversityNCT06654882Written as Tofacitinib
- Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren DiseaseRecruitingPhase 2National Institute of Dental and Craniofacial Research (NIDCR)NCT07281456Written as Tofacitinib
- A Study to Evaluate the Safety and Pharmacokinetics of Multiple Doses Upadacitinib, Tofacitinib, and Baricitinib in Healthy Adult VolunteersRecruitingPhase 1AbbVieNCT07843693Written as Tofacitinib
- A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)RecruitingPhase 4TakedaNCT06095128Written as Tofacitinib
- Modulation of the Immune System in Down Syndrome for Improved Outcomes and Neurodevelopment - 1RecruitingPhase 2University of Colorado, DenverNCT07598643Written as Tofacitinib Oral Solution
- JAK Inhibitor Dose TAPering Strategy StudyRecruitingPhase 4University Hospital, ToulouseNCT06687551Written as Tofacitinib 5 mg twice daily
- Tofacitinib Plus Imatinib in Moderate-to-Severe Palmoplantar PustulosisNot yet recruitingPhase 3Second Affiliated Hospital, Zhejiang University, School of MedicineNCT07530367Written as Tofacitinib
- A Phase 2 Trial to Assess Safety and Efficacy of Tofacitinib 2% Cream in the Treatment of Cutaneous T-cell Lymphoma (CTCL), Stages IA, IB, and IIARecruitingPhase 2M.D. Anderson Cancer CenterNCT06698822Written as tofacitinib 2% cream
- Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder ArthroplastyRecruitingPhase 2NYU Langone HealthNCT07138898Written as Tofacitinib
- Treatment of Rheumatoid Arthritis With DMARDs: Predictors of ResponseRecruitingPhase 3University of NebraskaNCT03414502Written as Tofacitinib
- Utilization of a Microdevice for Psoriasis and Atopic DermatitisNot yet recruitingPhase 4University of California, San FranciscoNCT07352566Written as Tofacitinib
- Comparison of Methotrexate and Tofacitinib in Chronic Plaque PsoriasisNot yet recruitingNot applicablePak Emirates Military HospitalNCT07581418Written as Tofacitinib
- Tofacitinib for Glucocorticoid-Resistant Moderate-to-Severe Thyroid Eye DiseaseRecruitingPhase 2The First Affiliated Hospital of Xiamen UniversityNCT07547930Written as Tofacitinib
- Major Adverse Cardiovascular Events (MACE) in Rheumatoid Arthritis Patient With Moderate to Severe Disease Activity Treated With Tofacitinib and Statins vs TNF Inhibitors: TOFSTAT CLINICAL TRIALRecruitingPhase 4Shaikh Zayed Hospital, LahoreNCT07554820Written as Tofacitinib 5 MG
- A Precision Medicine Trial for Patients With Relapsed or Refractory T Cell ALLNot yet recruitingPhase 2Philippe ROUSSELOTNCT07522801Written as Venetoclax + Tofacitinib
- Study of Salvage Therapy to Treat Patients With Granulomatosis With PolyangiitisRecruitingPhase 3Assistance Publique - Hôpitaux de ParisNCT04871191Written as Tofacitinib
- The Efficacy and Safety of Anti-inflammation Treatment (Hirudoid Introduction Followed by Yellow Light Therapy) Combined With Tofacitinib and Doxycycline in Chinese Adult Patients With Mild to Moderate Erythematous Telangiectatic RosaceaRecruitingNot applicableThe Fourth Affiliated Hospital of Zhejiang University School of MedicineNCT07343635Written as Tofacitinib
- Tofacitinib vs Methotrexate for Severe Alopecia Areata (TOFA-MTX-AA)Not yet recruitingPhase 4Hayat Abad Medical Complex, PeshawarNCT07406204Written as Tofacitinib
- Stand UP to Rheumatoid Arthritis (SUPRA)RecruitingNot applicableMarie Hudson, MDNCT05305066Written as JAKi
- Combination Therapy With Infliximab and Tofacitinib for Acute Severe Ulcerative Colitis - CINTO TrialNot yet recruitingPhase 2Asian Institute of Gastroenterology, IndiaNCT07297069Written as Tofacitinib
See all 184 studies that test tofacitinib →
Given in every arm · 4 — tofacitinib is usual care beside what is tested
- Tofacitinib in Recurrent GBM PatientsCompletedPhase 3University of Texas Southwestern Medical CenterNCT05326464Written as Tofacitinib 10mg
- The Efficacy and Safety of Tofacitinib (TF) With Iguratimod (IGU) on RACompletedPhase 4Qilu Hospital of Shandong UniversityNCT04928066Written as Tofacitinib
- Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and Other Mesothelin Expressing Solid TumorsCompletedPhase 1National Cancer Institute (NCI)NCT04034238Written as Tofacitinib
- Study Of The Effects Of Atorvastatin On Cholesterol Levels In Rheumatoid Arthritis Patients Taking CP-690,550CompletedPhase 2PfizerNCT01059864Written as CP-690,550
As the comparator · 12 — what is tested is compared with tofacitinib
- A Clinical Trial of TQH3906 Capsules in the Treatment of Active Psoriatic ArthritisRecruitingPhase 2Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.NCT07406035Written as Tofacitinib Citrate Tablet 5 mg
- Efficacy and Safety of HS-10374 Compared to Placebo in Adults With Active Psoriatic ArthritisRecruitingPhase 2Hansoh BioMedical R&D CompanyNCT06176508Written as Tofacitinib 5Mg Tab,Oral
- Baricitinib in the Treatment of Refractory Axial Spondyloarthritis Patients: A Comparison With TofacitinibRecruitingPhase 2Bangabandhu Sheikh Mujib Medical University, Dhaka, BangladeshNCT06114407Written as Tofacitinib 5 mg
- Comparison of Adalimumab and Tofacitinib in the Treatment of Active Takayasu ArteritisRecruitingPhase 4Chinese SLE Treatment And Research GroupNCT05151848Written as Tofacitinib 5 MG
- A Phase 3 Study Comparing TLL-018 to Tofacitinib in RA Subjects With Inadequate Response or Intolerance to bDMARDsCompletedPhase 3Hangzhou Highlightll Pharmaceutical Co., LtdNCT06020144Written as Tofacitinib
- Efficacy and Safety Clinical Study of VC005 Tablets in Subjects With Active Ankylosing Spondylitis.CompletedPhase 2Jiangsu vcare pharmaceutical technology co., LTDNCT05814939Written as Tofacitinib Citrate Tablets
- The Safety and Efficacy of TLL-018 in Active Rheumatoid ArthritisCompletedPhase 2Hangzhou Highlightll Pharmaceutical Co., LtdNCT05133297Written as Tofacitinib
- A Study of JNJ-64251330 in Healthy ParticipantsCompletedPhase 1Janssen Research & Development, LLCNCT04552197Written as Tofacitinib
- Study to Evaluate Safety, Tolerability, and Efficacy of GS-5718 in Participants With Active Rheumatoid Arthritis Who Have an Inadequate Response to Disease-modifying Antirheumatic Drug(s) (bDMARDs) TreatmentWithdrawnPhase 2Gilead SciencesNCT05165771Written as Tofacitinib 5 mg
- Study to Evaluate HL-TOF Tab. 5 mg Compared With XelJanz Tab. in Healthy VolunteersCompletedPhase 1Hanlim Pharm. Co., Ltd.NCT04114461Written as Xeljanz tab. 5mg
- Safety and Efficacy of Pf-06650833 In Subjects With Rheumatoid Arthritis, With An Inadequate Response To MethotrexateCompletedPhase 2PfizerNCT02996500Written as Tofacitinib
- A Study in Healthy Adults and Adult Subjects With Rheumatoid Arthritis to Evaluate the Safety, Tolerability and Pharmacokinetics After Multiple Doses of ABT-494CompletedPhase 1AbbVie (prior sponsor, Abbott)NCT01741493Written as Tofacitinib
Codes
What other systems call tofacitinib · ClinicalTrials.gg INT004585
- MeSH (NLM) C479163tofacitinibConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 87LA6FU830TOFACITINIBConfirmed FDA, NLM, Wikidata
- RxNorm 1357536Confirmed FDA, Wikidata
- Wikidata Q3530324tofacitinibConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C95800TofacitinibOne source FDA
- DrugBank DB08895One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C479163 | tofacitinib | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 87LA6FU830 | TOFACITINIB | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1357536 | — | Confirmed FDA, Wikidata |
| Wikidata | Q3530324 | tofacitinib | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C95800 | Tofacitinib | One source FDA |
| DrugBank | DB08895 | — | One source Wikidata |
Also registered as tofacitinib citrate (UNII O1FF4DIV0D · RxNorm 1358492).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.