Drug
Etanercept clinical trials
Also written Enbrel, HD203 and CHS-0214.
Includes 2 studies of GP2015.
- studies test it
- 257
- open now
- 13
- in phase 3
- 68
- first study started
- 1997
Keep track of what changes. Save the Etanercept studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
252 studies that test it; most in 2005 (20)
| Year | Studies |
|---|---|
| 1997 | 2 |
| 1998 | 1 |
| 1999 | 5 |
| 2000 | 7 |
| 2001 | 6 |
| 2002 | 10 |
| 2003 | 9 |
| 2004 | 18 |
| 2005 | 20 |
| 2006 | 19 |
| 2007 | 19 |
| 2008 | 15 |
| 2009 | 16 |
| 2010 | 12 |
| 2011 | 11 |
| 2012 | 8 |
| 2013 | 8 |
| 2014 | 10 |
| 2015 | 8 |
| 2016 | 16 |
| 2017 | 6 |
| 2018 | 4 |
| 2019 | 5 |
| 2020 | 2 |
| 2021 | 5 |
| 2022 | 2 |
| 2023 | 3 |
| 2024 | 1 |
| 2025 | 3 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 3
- Phase 1
- 34
- Phase 2
- 63
- Phase 3
- 68
- Phase 4
- 91
- No phase
- 17
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 114 · Other 143
Amgen (37) · Wyeth is now a wholly owned subsidiary of Pfizer (32) · Pfizer (18) · Massachusetts General Hospital (6) · National Institute of Allergy and Infectious Diseases (NIAID) (6) · University of Michigan Rogel Cancer Center (5) · Sun Yat-sen University (4) · Hanwha Chemical (4)
Often tested with
Tested in the same studies.
Adalimumab (16) · Methotrexate (15) · Infliximab (13) · Hydroxychloroquine (8) · Tofacitinib (8) · Sulfasalazine (8) · Tacrolimus (6) · Certolizumab Pegol (6)
Studies
Open first, then newest update. How each study uses Etanercept is read from its arms, and is right about nine times in ten.
Testing it · 257
- Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder ArthroplastyRecruitingPhase 2NYU Langone HealthNCT07138898Written as Etanercept
- Ruxolitinib Plus Etanercept vs Ruxolitinib for Steroid-Refractory Severe Acute GVHDRecruitingNot applicableFirst Affiliated Hospital of Zhejiang UniversityNCT07184853Written as Etanercept (Enbrel)
- Treatment of Rheumatoid Arthritis With DMARDs: Predictors of ResponseRecruitingPhase 3University of NebraskaNCT03414502Written as Etanercept
- Utilization of a Microdevice for Psoriasis and Atopic DermatitisNot yet recruitingPhase 4University of California, San FranciscoNCT07352566Written as Etanercept
- Study of the Efficacy and Safety of Etanercept Treatment in Patients With SAPHO SyndromeRecruitingPhase 2/3National Institute of Geriatrics, Rheumatology and Rehabilitation, PolandNCT06011889Written as Etanercept
- RENAL: TNF-alpha Inhibitor for Improving Renal Dysfunction and Primary Graft Dysfunction After Lung TransplantEnrolling by invitationEarly Phase 1Northwestern UniversityNCT05950724Written as Etanercept Injection [Enbrel]
- Stand UP to Rheumatoid Arthritis (SUPRA)RecruitingNot applicableMarie Hudson, MDNCT05305066Written as TNFi
- GD2 Specific CAR and Interleukin-15 Expressing Autologous NKT Cells to Treat Children With NeuroblastomaRecruitingPhase 1Baylor College of MedicineNCT03294954Written as GINAKIT cells + Etanercept
- Effect and Safety of Benzathine Penicillin Combined With Etanercept on SpondyloarthritisRecruitingPhase 4Nanfang Hospital, Southern Medical UniversityNCT06707194Written as Etanercept
- Advanced Therapeutics in Rheumatoid Arthritis (RA)RecruitingPhase 4London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sNCT03976245Written as Etanercept
- STep-up and Step-down Therapeutic Strategies in Childhood ARthritiSRecruitingPhase 3Istituto Giannina GasliniNCT03728478Written as Etanercept
- Effects of Treatment With Biological Agents on Vascular and Cardiac Function in PsoriasisRecruitingPhase 4University of AthensNCT02144857Written as etanercept
- Impact of Tapering Immunosuppressants on Maintaining Minimal Disease Activity in Adult Subjects With Psoriatic ArthritisRecruitingPhase 3University of Erlangen-Nürnberg Medical SchoolNCT04610476Written as Etanercept
- TNF-α Treatment of Blast-Induced TinnitusActive, not recruitingPhase 2Wayne State UniversityNCT04066348Written as Etanercept
- TNF and Glucocorticoid Antagonist for GWI Associated Multi-symptom Disease Homeostasis ResetCompletedPhase 1Nova Southeastern UniversityNCT04254627Written as Etanercept
- Anti-inflammatory Therapy to Improve Outcomes After TPIATCompletedPhase 4University of MinnesotaNCT02713997Written as etanercept
- Treatment Tapering in JIA With Inactive DiseaseCompletedPhase 3Assistance Publique - Hôpitaux de ParisNCT02840175Written as etanercept
- Rotation or Change of Biotherapy After First Anti-TNF Treatment Failure for Rheumatoid ArthritisCompletedPhase 4University Hospital, Strasbourg, FranceNCT01000441Written as infliximab, etanercept, adalimumab
- NATIENS: Optimal Management and Mechanisms of SJS/TENCompletedPhase 3Vanderbilt University Medical CenterNCT02987257Written as Etanercept 50 mg sc day 1 and day 4
- COBRA-Slim With or Without Fast Access to TNF Blockade for Remission Induction in Early RACompletedPhase 4P. VerschuerenNCT03649061Written as Etanercept 50 MG/ML
See all 257 studies that test Etanercept →
Given in every arm · 16 — Etanercept is usual care beside what is tested
- A Study of Tildrakizumab in Pediatric Subjects With Chronic Plaque PsoriasisActive, not recruitingPhase 2/3Sun Pharmaceutical Industries LimitedNCT03997786Written as Etanercept
- Safety, Tolerability, Pharmacokinetics, and Efficacy of Acapatamab in Subjects With mCRPCTerminatedPhase 1AmgenNCT03792841Written as Etanercept
- Stem Cell Mobilization (Plerixafor) and Immunologic Reset in Type 1 Diabetes (T1DM)CompletedPhase 1/2University of AlbertaNCT03182426Written as Etanercept
- Immune Effects of Vedolizumab With or Without Anti-TNF Pre-treatment in T1DCompletedEarly Phase 1Benaroya Research InstituteNCT05281614Written as Etanercept
- Study of Etanercept Monotherapy vs Methotrexate Monotherapy for Maintenance of Rheumatoid Arthritis RemissionCompletedPhase 3AmgenNCT02373813Written as etanercept pre-filled syringe subcutaneous injection
- Safety and Effectiveness of Low Molecular Weight Sulfated Dextran in Islet TransplantationCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT00789308Written as Enbrel® (Etanercept)
- Very Early Versus Delayed Etanercept in Patients With RACompletedPhase 4University of LeedsNCT02433184Written as Etanercept
- Niclosamide With Etanercept in Rheumatoid ArthritisCompletedPhase 1/2Faiq GorialNCT03160001Written as Etanercept
- Efficacy, Safety and Immunogenicity of Enerceptan Compared to Enbrel in Rheumatoid ArthritisCompletedPhase 3Gema Biotech S.A.NCT03332719Written as Etanercept
- Efficacy and Safety of Etanercept 50 mg Once Weekly Plus As Needed Topical Agent in Moderate to Severe Plaque PsoriasisCompletedPhase 3AmgenNCT01313221Written as etanercept
- Peritransplant Deoxyspergualin in Islet Transplantation in Type 1 DiabetesCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT00434850Written as Etanercept
- Safety and Tolerability of Rituxan With Methotrexate and Etanercept or Methotrexate and Adalimumab in Patients With Active Rheumatoid ArthritisTerminatedPhase 2BiogenNCT00298272Written as Etanercept
- Trial of an Injectable Biologic and U0279 as Combination Therapy for Severe Plaque-Type PsoriasisWithdrawnPhase 4Stiefel, a GSK CompanyNCT00832364Written as Etanercept
- The Efficacy and Safety of Adding Methotrexate to Etanercept in PsoriasisCompletedPhase 3AmgenNCT01001208Written as Etanercept
- Open Label Study Etanercept's Maintenance Dose in Obese Patients With Moderate to Severe Plaque Type PsoriasisCompletedNot applicableUniversity of California, San FranciscoNCT00800982Written as etanercept
- Safety and Efficacy of Combining nbUVB to Etanercept in PatientsCompletedPhase 4Innovaderm Research Inc.NCT00640393Written as Etanercept
As the comparator · 27 — what is tested is compared with Etanercept
- A Study to Compare Efficacy, Pharmacokinetics, Safety and Immunogenicity of MB04 [Proposed Etanercept Biosimilar] to Enbrel® [EU-sourced] in Rheumatoid ArthritisCompletedPhase 3mAbxience Research S.L.NCT06596772Written as Enbrel (etanercept)
- A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric ParticipantsActive, not recruitingPhase 3Janssen Research & Development, LLCNCT03451851Written as Etanercept
- A Study to Evaluate Safety and Efficacy of ASP015K in Patients With Rheumatoid Arthritis (RA) Who Had an Inadequate Response to DMARDsCompletedPhase 3Astellas Pharma IncNCT02308163Written as Etanercept
- Pediatric Study in Children and Adolescents With Severe Plaque PsoriasisCompletedPhase 3Novartis PharmaceuticalsNCT02471144Written as Active Comparator: Etanercept
- Rheumatoid Arthritis Treatment After First Anti-TNF INvestiGationTerminatedPhase 4Mario Negri Institute for Pharmacological ResearchNCT03100253Written as Etanercept
- A Study to Evaluate the Efficacy and Safety/Tolerability of Subcutaneous Tildrakizumab (SCH 900222/MK-3222) in Participants With Moderate-to-Severe Chronic Plaque Psoriasis Followed by a Long-term Extension Study (MK-3222-011)CompletedPhase 3Sun Pharmaceutical Industries LimitedNCT01729754Written as Etanercept 50 mg
- A Study to Evaluate the Efficacy and Safety/Tolerability of Subcutaneous MK-3222 in Participants With Moderate-to-Severe Chronic Plaque Psoriasis (MK-3222-012)WithdrawnPhase 3Sun Pharmaceutical Industries LimitedNCT01936688Written as Etanercept 50 mg
- Safety Study Of Tofacitinib Versus Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid ArthritisCompletedPhase 4PfizerNCT02092467Written as etanercept
- Efficacy and Safety Study of Certolizumab Pegol (CZP) Versus Active Comparator and Placebo in Subjects With Plaque Psoriasis (PSO)CompletedPhase 3UCB Biopharma S.P.R.L.NCT02346240Written as Etanercept
- Safety and Efficacy of Secukinumab Compared to Etanercept in Subjects With Moderate to Severe, Chronic Plaque-Type PsoriasisCompletedPhase 3Novartis PharmaceuticalsNCT01358578Written as etanercept
- A Study in Participants With Moderate to Severe Psoriasis (UNCOVER-3)CompletedPhase 3Eli Lilly and CompanyNCT01646177Written as 50 mg etanercept
- A Phase 3 Study in Participants With Moderate to Severe Psoriasis (UNCOVER-2)CompletedPhase 3Eli Lilly and CompanyNCT01597245Written as 50 mg etanercept
- Tolerance, Pharmacokinetics and Preliminary Efficacy of T0001 in RA (Rheumatoid Arthritis)TerminatedPhase 1Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.NCT02481180Written as Enbrel
- A Phase 3, Multi Site, Randomized, Double Blind, Placebo Controlled Study Of The Efficacy And Safety Comparing CP- 690,550 And Etanercept In Subjects With Moderate To Severe Chronic Plaque PsoriasisCompletedPhase 3PfizerNCT01241591Written as Etanercept 50 mg
- A Study Comparing SB4 to Enbrel® in Subjects With Moderate to Severe Rheumatoid Arthritis Despite Methotrexate TherapyCompletedPhase 3Samsung Bioepis Co., Ltd.NCT01895309Written as Enbrel (etanercept)
- An Evaluation of Sarilumab Plus Methotrexate Compared to Etanercept Plus Methotrexate in RA Patients Not Responding to Adalimumab Plus MethotrexateTerminatedPhase 3SanofiNCT01764997Written as Etanercept
- A Study of Tocilizumab in Comparison to Etanercept in Participants With Rheumatoid Arthritis and Cardiovascular Disease Risk FactorsCompletedPhase 4Hoffmann-La RocheNCT01331837Written as Etanercept
- A Pilot Study of MSCs Iufusion and Etanercept to Treat Ankylosing SpondylitisStatus unknownPhase 2/3Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityNCT02809781Written as Etanercept
- Compare Actions in Healthy Volunteer of 50 mg Etanercept Injection Using an Auto-injector Device and Manual InjectionCompletedPhase 1AmgenNCT02799498Written as Etanercept (ENBREL®)
- A Study Comparing LBEC0101 to Enbrel® in Subjects With Active Rheumatoid Arthritis Despite Methotrexate TherapyStatus unknownPhase 3LG Life SciencesNCT02357069Written as Enbrel
Showing 20 of 27.
Codes
What other systems call Etanercept · ClinicalTrials.gg INT006542
- MeSH (NLM) D000068800EtanerceptConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) OP401G7OJCETANERCEPTConfirmed FDA, NLM, Wikidata
- RxNorm 214555Confirmed FDA, Wikidata
- Wikidata Q415343etanerceptConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C2381EtanerceptOne source FDA
- DrugBank DB00005One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000068800 | Etanercept | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | OP401G7OJC | ETANERCEPT | Confirmed FDA, NLM, Wikidata |
| RxNorm | 214555 | — | Confirmed FDA, Wikidata |
| Wikidata | Q415343 | etanercept | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C2381 | Etanercept | One source FDA |
| DrugBank | DB00005 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.