Drug
Ezetimibe clinical trials
Also written Zetia, Ezetrol, MK0653 and SCH 58235.
- studies test it
- 213
- open now
- 13
- in phase 3
- 76
- first study started
- 2000
Keep track of what changes. Save the Ezetimibe studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
- MK0653
- 13
Combined with it in one product
Studies by the year they started
213 studies that test it; most in 2005 (22)
| Year | Studies |
|---|---|
| 2000 | 4 |
| 2001 | 6 |
| 2002 | 2 |
| 2003 | 16 |
| 2004 | 13 |
| 2005 | 22 |
| 2006 | 12 |
| 2007 | 22 |
| 2008 | 8 |
| 2009 | 13 |
| 2010 | 4 |
| 2011 | 4 |
| 2012 | 4 |
| 2013 | 8 |
| 2014 | 8 |
| 2015 | 5 |
| 2016 | 5 |
| 2017 | 10 |
| 2018 | 6 |
| 2019 | 2 |
| 2020 | 7 |
| 2021 | 5 |
| 2022 | 6 |
| 2023 | 3 |
| 2024 | 5 |
| 2025 | 8 |
| 2026 | 5 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 30
- Phase 2
- 18
- Phase 3
- 76
- Phase 4
- 67
- No phase
- 21
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 124 · Other 89
Organon and Co (69) · Chong Kun Dang Pharmaceutical (9) · Daiichi Sankyo (6) · Sanofi (5) · NewAmsterdam Pharma (3) · University of California, San Diego (3) · Esperion Therapeutics, Inc. (3) · University of Sao Paulo (3)
Often tested with
Tested in the same studies.
Simvastatin (45) · Rosuvastatin (31) · Atorvastatin (29) · Bempedoic acid (11) · Telmisartan (11) · Hydroxymethylglutaryl-CoA Reductase Inhibitors (10) · CKD-348 (8) · Levamlodipine (8)
Studies
Open first, then newest update. How each study uses Ezetimibe is read from its arms, and is right about nine times in ten.
Testing it · 213
- Ezetimibe Utilization Early After Acute Myocardial Infarction, "EzAMI Trial"RecruitingNot applicableCairo UniversityNCT04701242Written as Ezetimibe 10mg
- Aggressive Lipid Lowering Therapy in ICI-Treated MelanomaRecruitingNot applicableUniversity of Colorado, DenverNCT07704918Written as Statins (atorvastatin, rosuvastatin, simvastatin, or pravastatin), +/- ezetimibe, +/- PCSK9 inhibitor (alirocumab, evolocumab, inclisiran)
- A Study of Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without Cardiovascular EventsNot yet recruitingPhase 3Daiichi SankyoNCT07474649Written as Ezetimibe
- LDL Cholesterol Reduction Following Ezetimibe InitiationRecruitingPhase 4Universidade do PortoNCT07839741Written as Ezetimibe
- Ezetimibe for Arrhythmia Recurrence After AF AblationNot yet recruitingPhase 4Second Affiliated Hospital, Zhejiang University, School of MedicineNCT07752758Written as Ezetimibe
- Livalozet Versus High-intensity Statin in Older Patients With Coronary Artery Disease Undergoing Percutaneous Coronary InterventionNot yet recruitingNot applicableSamsung Medical CenterNCT07626840Written as Pitavastatin/ezetimibe
- Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate CancerRecruitingPhase 2Cedars-Sinai Medical CenterNCT06437574Written as Ezetimibe
- Early Statin-Ezetimibe Combination vs. Statin Monotherapy in Stroke With AtherosclerosisRecruitingPhase 2Chang Gung Memorial HospitalNCT07307989Written as statin + ezetimibe
- Cholesterol Lowering and Residual Risk in Diabetes, Type 1RecruitingPhase 4NYU Langone HealthNCT05641753Written as Ezetimibe Tablets
- Low Dose Rosuvastatin Plus Ezetimibe Versus High-dose Rosuvastatin in AMIRecruitingPhase 4Kiyuk Chang, MD,PhDNCT04499859Written as Ezetimibe 10mg + Rosuvastatin 5mg
- To Evaluate the Efficacy and Safety of Co-administrated HODO-2224-1 and HODO-2224-2 in Patients With Essential Hypertension and Primary HypercholesterolemiaEnrolling by invitationPhase 3Hyundai PharmNCT06646354Written as Ezetimibe/Rosuvastatin/Candesartan/Amlodipine
- Effect of PCSK9 Inhibitors on Calcific Aortic Valve StenosisRecruitingPhase 3Beijing Anzhen HospitalNCT04968509Written as PCSK9 inhibitors and statins with or without ezetimibe
- Intensive Lipid-lowering in Patients With STEMI and NSTEMI (Germany on Target)Not yet recruitingNot applicableJena University HospitalNCT05587621Written as statins, ezetimibe, bempedoic acid, evolocumab, alirocumab, inclisiran
- Dual vs Triple Lipid-Lowering Therapy in Type 2 Diabetes Mellitus Patients With Elevated LDL CholesterolCompletedPhase 4Bahria UniversityNCT07255820Written as Rosuvastatin + Ezetimibe
- Comparison of Moderate-Intensity Statin Plus Ezetimibe vs. High-Intensity Statin for Coronary Plaque StabilizationActive, not recruitingPhase 4Korea University Anam HospitalNCT06767345Written as Rosuvastatin/ezetimibe
- Efficacy and Safety of Ezetimibe/Rosuvastatin and Amlodipine Patients With High Blood Pressure and High CholesterolCompletedPhase 3Celltrion Pharm, Inc.NCT07564726Written as Ezetimibe/Rosuvastatin
- Long-term Comparison of Pitavastatin/Ezetimibe and Pitavastatin in Patients With Hypercholesterolemia and Elevated TriglyceridesActive, not recruitingPhase 4JW PharmaceuticalNCT07442630Written as Ezetimibe 10 mg
- Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid / Ezetimibe, and AtorvastatinCompletedPhase 1Daiichi SankyoNCT07268625Written as Ezetimibe
- A Study Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid, Ezetimibe, and AtorvastatinCompletedPhase 1Daiichi SankyoNCT07235189Written as Ezetimibe
- Evaluating Bioequivalence of a Fixed Dose Combination Versus Tablets of Bempedoic Acid / Ezetimibe and RosuvastatinCompletedPhase 1Daiichi SankyoNCT07201545Written as Ezetimibe
See all 213 studies that test Ezetimibe →
Given in every arm · 20 — Ezetimibe is usual care beside what is tested
- Early Triple Lipid-Lowering Therapy With Bempedoic Acid After Acute Coronary SyndromeRecruitingPhase 4Taipei Medical University HospitalNCT07824323Written as Ezetimibe
- Efficacy and Safety Study of Digital Cognitive Training and PCSK9 Inhibitor-Enhanced Lipid-lowering Strategy in Patients With Intracranial Atherosclerotic Stenosis: A 2x2 Factorial, Randomized, Parallel-Group, Multicenter TrialNot yet recruitingPhase 4Peking Union Medical College HospitalNCT07605130Written as Ezetimibe
- Early Intensive Lipid-Lowering With Inclisiran for Plaque Stabilization in Acute Coronary SyndromeNot yet recruitingPhase 4Seoul National University Bundang HospitalNCT07799779Written as Ezetimibe
- Triple vs Dual Lipid-Lowering Therapy for LDL-C Reduction in Acute Coronary SyndromeNot yet recruitingPhase 4Punjab Institute of CardologyNCT07508254Written as Ezetimibe 10 mg
- A Study to Investigate the Pharmacokinetics, Safety, Tolerability, and Efficacy of AZD0780 With Ezetimibe Combinations in Healthy Adults With Elevated LDL-C.CompletedPhase 1AstraZenecaNCT06742853Written as Ezetimibe
- Effect of Early Initiation of Evolocumab on Lipid Profiles Changes in Patients With ACS Undergoing PCICompletedPhase 4Yonsei UniversityNCT05661552Written as Ezetimibe 10mg
- A Study to Evaluate the Safety and Efficacy of the PCSK9 Inhibitor AK102 in Patients With HoFHCompletedPhase 2AkesoNCT03933293Written as Ezetimibe
- Durable Effect of PCSK9 Antibody CompARed wiTh placEbo StudyCompletedPhase 3AmgenNCT01516879Written as Ezetimibe
- Safety and Tolerability Study of Ezetimibe (SCH 058235/MK-0653) Plus Atorvastatin or Simvastatin in Homozygous Familial Hypercholesterolemia (P01417/MK-0653-019)CompletedPhase 3Organon and CoNCT03885921Written as Ezetimibe
- Evolocumab Plus Ezetimibe in Haemodialized Statin-intolerant Patients With HypercholesterolemiaStatus unknownPhase 4Policlinico Casilino ASL RMBNCT04659525Written as Ezetimibe
- Evolocumab Plus Ezetimibe in High Risk Haemodialized Statin Intolerant PatientsStatus unknownPhase 4Policlinico Casilino ASL RMBNCT04397653Written as Ezetimibe
- Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C (CLEAR Tranquility)CompletedPhase 3Esperion Therapeutics, Inc.NCT03001076Written as Ezetimibe
- A Study of LY3015014 in Participants With High CholesterolCompletedPhase 2Eli Lilly and CompanyNCT01890967Written as Ezetimibe
- Evaluation of Effect of Alirocumab on Coronary Atheroma Volume in Japanese Patients Hospitalized for Acute Coronary Syndrome With HypercholesterolemiaCompletedPhase 4SanofiNCT02984982Written as Ezetimibe
- A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Administering Multiple Oral Doses of GSK1292263 Alone and With AtorvastatinCompletedPhase 2GlaxoSmithKlineNCT01218204Written as 10mg ezetimibe
- Dose Ranging Study Of Bococizumab (PF-04950615; RN316) In Hypercholesterolemic Japanese SubjectsCompletedPhase 2PfizerNCT02055976Written as Ezetimibe
- A Study to Compare the Pharmacokinetics of DP-R207 in Comparison to Each Component Administered AloneCompletedPhase 1Alvogen KoreaNCT02730689Written as Ezetimibe
- Rosuvastatin for Reduction of Myocardial Damage and Systemic Inflammation During Coronary AngioplastyTerminatedPhase 3G. d'Annunzio UniversityNCT02205775Written as Ezetimibe
- Safety and Efficacy Study Comparing ABT-335 Coadministered With Atorvastatin and Ezetimibe to Atorvastatin Coadministered With Ezetimibe in Subjects With Multiple Abnormal Lipid (Fat) Levels in the BloodCompletedPhase 3AbbottNCT00639158Written as ezetimibe
- Comparative Study of the Effect of Ezetimibe Versus Extended-Release Niacin on AtherosclerosisTerminatedPhase 4Walter Reed Army Medical CenterNCT00397657Written as ezetimibe
As the comparator · 35 — what is tested is compared with Ezetimibe
- Assessing Coronary Non-Culprit Plaque Early with Start of PCSK9 Inhibitors in Acute Myocardial Infarction (ACCESS-AMI)Not yet recruitingNot applicableYun Dai ChenNCT06854523Written as Statin+ezetimibe
- Statin and Bone HealthEnrolling by invitationPhase 4The University of Hong KongNCT05613400Written as Ezetimibe 10mg
- A Study to Evaluate the Efficacy and Safety of Enlicitide (MK-0616, Oral PCSK9 Inhibitor) Compared With Ezetimibe or Bempedoic Acid or Ezetimibe and Bempedoic Acid in Adults With Hypercholesterolemia (MK-0616-018/CORALreef AddOn)CompletedPhase 3Merck Sharp & Dohme LLCNCT06450366Written as Ezetimibe
- Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy.CompletedPhase 3Novartis PharmaceuticalsNCT05763875Written as Ezetimibe
- Switching to Rosuvastatin Versus Adding Ezetimibe to Atorvastatin Versus Doubling the Dose of Atorvastatin in Patients With Hypercholesterolemia and Risk Factors (P03708)TerminatedPhase 4Organon and CoNCT00651378Written as Ezetimibe + Atorvastatin
- Study of HSK31679 in Subjects With Hypercholesterolemia With Nonalcoholic Fatty Liver Disease（NAFLD）CompletedPhase 2Haisco Pharmaceutical Group Co., Ltd.NCT05795517Written as Ezetimibe 10mg
- Effects of Statin for Elderly Patients With Atherosclerotic Cardiovascular DiseaseCompletedPhase 4Korea University Anam HospitalNCT04826354Written as Rosuvastatin and Ezetimibe
- Monoclonal Antibody Against PCSK9 to Reduce Elevated LDL-C in Subjects Currently Not Receiving Drug Therapy for Easing Lipid Levels-2CompletedPhase 3AmgenNCT01763827Written as Ezetimibe
- LDL-C Assessment With PCSK9 Monoclonal Antibody Inhibition Combined With Statin Therapy-2CompletedPhase 3AmgenNCT01763866Written as Ezetimibe
- Monoclonal Antibody Against PCSK9 to Reduce Elevated Low-density Lipoprotein Cholesterol (LDL-C) in Adults Currently Not Receiving Drug Therapy for Easing Lipid LevelsCompletedPhase 2AmgenNCT01375777Written as Ezetimibe
- A Study to Evaluate the Efficacy and Safety of AD-221 and AD-221ACompletedPhase 3Addpharma Inc.NCT05131997Written as AD-221B
- Compare the Efficacy and Safety of 1PC111 With Pitavastatin and Ezetimibe in Patients With Primary Hypercholesterolemia or Mixed DyslipidemiaCompletedPhase 3Orient Pharma Co., Ltd.NCT04643093Written as Ezetimibe
- A Study to Determine the Bioequivalence of SCH 900068 Compared to Marketed Products (Protocol No. P07551)CompletedPhase 1Organon and CoNCT01236430Written as Ezetimibe
- Investigating the Lowest Threshold of Vascular Benefits From LDL Cholesterol Lowering in Patients With Stable CV DiseaseStatus unknownNot applicableCambridge University Hospitals NHS Foundation TrustNCT03355027Written as Ezetimibe 10Mg Tablet
- A Phase 3 Study to Compare the Efficacy and Safety of Co-administered HGP0608, HGP0904 and HCP1306 Versus HCP1701 in Patients With Hypertension and DyslipidemiaCompletedPhase 3Hanmi Pharmaceutical Company LimitedNCT04074551Written as Rosuvastatin and Ezetimibe
- Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-4CompletedPhase 3AmgenNCT02634580Written as Ezetimibe
- Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects -2CompletedPhase 3AmgenNCT01763905Written as Ezetimibe
- Study of Alirocumab (REGN727/SAR236553) in Patients With Primary Hypercholesterolemia and Moderate, High, or Very High Cardiovascular (CV) Risk, Who Are Intolerant to Statins (ODYSSEY ALTERNATIVE)CompletedPhase 3Regeneron PharmaceuticalsNCT01709513Written as Ezetimibe
- Bempedoic Acid + Ezetimibe Fixed-Dose Combination (FDC) Study in Patients With Type 2 Diabetes and Elevated LDL-CCompletedPhase 2Esperion Therapeutics, Inc.NCT03531905Written as Ezetimibe 10 mg Oral Tablet
- Study of Alirocumab (REGN727/SAR236553) added-on to Rosuvastatin Versus Other Lipid Modifying Treatments (LMT) (ODYSSEY OPTIONS II)CompletedPhase 3Regeneron PharmaceuticalsNCT01730053Written as Ezetimibe
Showing 20 of 35.
Codes
What other systems call Ezetimibe · ClinicalTrials.gg INT006574
- MeSH (NLM) D000069438EzetimibeConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) EOR26LQQ24EZETIMIBEConfirmed FDA, NLM, Wikidata
- RxNorm 341248Confirmed FDA, Wikidata
- Wikidata Q417997ezetimibeConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C47529EzetimibeOne source FDA
- DrugBank DB00973One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000069438 | Ezetimibe | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | EOR26LQQ24 | EZETIMIBE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 341248 | — | Confirmed FDA, Wikidata |
| Wikidata | Q417997 | ezetimibe | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C47529 | Ezetimibe | One source FDA |
| DrugBank | DB00973 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.