Aortic Valve, Calcification of clinical trials

The registry lists 44 studies for Aortic Valve, Calcification of across more than 10 countries. 15 are recruiting or about to start. 18 of them are mainly about Aortic Valve, Calcification of (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-16.

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Status

Completed: 13
Recruiting: 8
Status unknown: 8
Active, not recruiting: 7
Not yet recruiting: 7
Withdrawn: 1

Phase

Phase 3: 4
Phase 2: 3
Early Phase 1: 1

Where

Germany: 7
Netherlands: 7
Denmark: 5
United States: 5
China: 4
France: 3

Who runs them

Anteris Technologies Ltd. (4) · Cardiawave SA (3) · Boston Scientific Corporation (3) · National and Kapodistrian University of Athens (2) · Instituto Nacional de Cardiologia Ignacio Chavez (2) · Institut für Pharmakologie und Präventive Medizin (2) · Beijing Anzhen Hospital (2) · Wuhan Union Hospital, China (2)

What is being tested here

Drugs under test in Aortic Valve, Calcification of studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Pioglitazone	1	0	1
Folic Acid	1	0	1
Ezetimibe	1	1	1
Colchicine	0	1	1
Denosumab	0	0	1
Alendronate	0	0	1
Eplerenone	0	0	1
Vitamin K 2	0	0	1

Coming up

3phase 3 studies under way

5studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 5, phase 3 first

Dec 2026Colchicine and Inflammation in Aortic Stenosis · Phase 3 · Radboud University Medical Center
Dec 2026Valvular Assessment of New Generation Aortic Replacement Devices · Instituto Dante Pazzanese de Cardiologia
Dec 2026Derivation and Validation of the Aortic Valve Echocardiographic Calcium Score to Confirm Severe Aortic Stenosis: the Echo-AVCS Study · Azienda Ospedaliera "Sant'Andrea"
Jun 2027Identification of Genetic Causes of Calcific Aortic Valve Disease · Beth Israel Deaconess Medical Center
Jun 2027Valvosoft Outcomes Registry for Real-World Evidence · Cardiawave SA

Who these studies take

Of the 8 Aortic Valve, Calcification of studies recruiting now, 6 (75%) set no upper age limit and 1 (13%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 8
Age	Women	Men
10	0 (0%)	0 (0%)
18	6 (75%)	6 (75%)
30	6 (75%)	6 (75%)
40	6 (75%)	6 (75%)
50	6 (75%)	6 (75%)
65	8 (100%)	8 (100%)
75	7 (88%)	7 (88%)
85	7 (88%)	7 (88%)

Across all 44 studies, recruiting or not: 5% stop at 75 or younger and 5% at 65; 18% take children; 0% are for women only and 0% for men only; 7% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 44 of 44. search them.