Alcohol-Related Disorders clinical trials
The registry lists 156 studies for Alcohol-Related Disorders across more than 10 countries. 23 are recruiting or about to start. 59 of them are mainly about Alcohol-Related Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 7 narrower conditions too, such as Alcoholism: 2,109 studies, 431 open.
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Who runs them
National Institute on Alcohol Abuse and Alcoholism (NIAAA) (9) · National Institute on Drug Abuse (NIDA) (8) · VA Office of Research and Development (7) · Yale University (6) · Kaiser Permanente (6) · University of Washington (4) · The Scripps Research Institute (4) · Northwell Health (4)
What is being tested here
Drugs under test in Alcohol-Related Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Spironolactone | 1 | 0 | 1 |
| Naltrexone | 0 | 1 | 7 |
| Disulfiram | 0 | 0 | 4 |
| Ethanol | 0 | 0 | 4 |
| Nalmefene | 0 | 3 | 3 |
| Fluoxetine | 0 | 0 | 2 |
| Venlafaxine | 0 | 1 | 2 |
| Nitrous Oxide | 0 | 0 | 2 |
| Dutasteride | 0 | 0 | 2 |
| Acetaminophen | 0 | 0 | 2 |
Drug classes tested here Opioid antagonists 10
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 10
- Nov 2026The Liver Care Trial · Zealand University Hospital
- Dec 2026Spironolactone in Alcohol Use Disorder (SAUD) · National Institute on Drug Abuse (NIDA)
- Dec 2026COVID-19 Pandemic Impact on Alcohol (PIA) - A Natural History Study · National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Feb 2027Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa · University of Maryland, College Park
- May 2027Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years · Emory University
- May 2027External Facilitation to Increase Prescribing of AUD Medications in the Psychiatric Setting · University of Maryland, Baltimore
- Jul 2027LaunchPad: Supporting Healthy Decisions and Preventing Drug Use After High School · Prevention Strategies, LLC
- Jul 2027Testing the Impact of Thrive App Versions on Alcohol Use and Posttraumatic Stress After Recent Sexual Assault · University of Washington
- Aug 2027The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD) · Yale University
- Aug 2027Centralized Virtual SBIRT for Pediatric Primary Care · Kaiser Permanente
Who these studies take
Of the 16 Alcohol-Related Disorders studies recruiting now, 5 (31%) set no upper age limit and 7 (44%) stop at 75 or younger. 3 (19%) take children under 18. 2 (13%) are for women only and 0 (0%) for men only; 5 (31%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 13 (81%) | 11 (69%) |
| 30 | 13 (81%) | 11 (69%) |
| 40 | 13 (81%) | 11 (69%) |
| 50 | 12 (75%) | 11 (69%) |
| 65 | 12 (75%) | 11 (69%) |
| 75 | 9 (56%) | 8 (50%) |
| 85 | 9 (56%) | 8 (50%) |
Across all 156 studies, recruiting or not: 53% stop at 75 or younger and 44% at 65; 12% take children; 3% are for women only and 3% for men only; 26% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Alcohol-Related Disorders studies take
Of 49 interventional studies with no phase under Alcohol-Related Disorders, half reached primary completion within 30 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 30 mo17–44 · 49 studies | — | 30 mo17–44 · 49 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 15, 2026.
Newly registered1
- Using Virtual Reality to Augment Brief Interventions for Heavy Drinking Young AdultsOct 28, 2026NCT07902154
Studies
Recruiting first, then most recently updated. Showing 50 of 156. Browse all 156 → or search them.
- Spironolactone in Alcohol Use Disorder (SAUD)RecruitingNCT05807139Phase 11 country
- The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among VeteransNot yet recruitingNCT06746727Not applicable1 country
- Using Virtual Reality to Augment Brief Interventions for Heavy Drinking Young AdultsNot yet recruitingNCT07902154Not applicable
- The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)RecruitingNCT06070649Phase 11 country
- Body-Focused Mindfulness as an Add-on Intervention in Inpatient Alcohol Use Disorder Treatment (MBI-AUD-PL)RecruitingNCT07706660Not applicable1 country
- Game-Based Intervention to Reduce Alcohol Use Among YouthRecruitingNCT07463118Not applicable1 country
- Intensive Care Outcome Prediction Using Admission Carbohydrate-deficient TransferrinRecruitingNCT076327161 country
- LaunchPad: Supporting Healthy Decisions and Preventing Drug Use After High SchoolNot yet recruitingNCT07655609Not applicable
- COVID-19 Pandemic Impact on Alcohol (PIA) - A Natural History StudyRecruitingNCT043918161 country
- CARRII Native Intervention Optimization TrialRecruitingNCT07547696Not applicable1 country
- Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive YearsRecruitingNCT05910580Not applicable1 country
- External Facilitation to Increase Prescribing of AUD Medications in the Psychiatric SettingRecruitingNCT07053098Not applicable1 country
- Intervention to Increase Intention to Change Alcohol/Tobacco Use in Veterans With Chronic DiseaseRecruitingNCT07039175Phase 31 country
- Cohort/Ethics Study of Patients With Severe Alcoholic Hepatitis Undergoing Early Liver TransplantationEnrolling by invitationNCT042341391 country
- Comparing Combined Behavioral Intervention and Ericksonian Hypnotherapy for Alcohol AddictionRecruitingNCT06916754Not applicable1 country
- Phase I, Dose-Escalation Study of Dihydromyricetin (DHM) to Treat Alcohol-Associated Liver DiseaseNot yet recruitingNCT05623501Phase 11 country
- Centralized Virtual SBIRT for Pediatric Primary CareRecruitingNCT06486688Not applicable1 country
- Recognition and Early Intervention for Alcohol and Substance Abuse in Adolescence in AdolescentRecruitingNCT06262958Not applicable1 country
- Efficacy and Safety of Dual-target Deep Brain Stimulation for Treatment-resistant Alcohol Use DisorderRecruitingNCT05884619Not applicable1 country
- The Liver Care TrialRecruitingNCT05855031Not applicable1 country
- Evaluating the Impact of Emergency Maternity HousingRecruitingNCT05428514Not applicable1 country
- Housing for Recovery InitiativeNot yet recruitingNCT05341830Not applicable
- Neurobiological Effects of Transcranial Direct Current Stimulation Treatment in Alcohol Use DisorderNot yet recruitingNCT04897295Not applicable
- Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETACompletedNCT04955795Not applicable1 country
- Longitudinal Changes in the Oral and Gut Microbiome of Individuals With Alcohol DependenceCompletedNCT029110771 country
- Characterization Imaging Instruments in Alcoholics and Non-AlcoholicsCompletedNCT021080801 country
- Neural and Behavioral Effects of Cognitive Bias Modification (CBM)TerminatedNCT04430543Not applicable1 country
- Diclofenac Dose Response StudyCompletedNCT06636227Phase 11 country
- Testing the Impact of Thrive App Versions on Alcohol Use and Posttraumatic Stress After Recent Sexual AssaultActive, not recruitingNCT06444295Not applicable1 country
- Addressing Barriers to Care for Substance Use Disorder Pilot StudyActive, not recruitingNCT06317987Not applicable1 country
- Feasibility and Effects of Activity Trackers Among Alcohol Users Receiving In-patient Treatment for Alcohol Use DisorderCompletedNCT06629493Not applicable1 country
- Common Elements Treatment Approach HIV Alcohol Reduction Trial in ZambiaCompletedNCT05121064Not applicable1 country
- Feasibility of the 5-Step Method in the U.S.Active, not recruitingNCT06565429Not applicable1 country
- Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South AfricaActive, not recruitingNCT05933226Not applicable1 country
- Implementing a Blended Care Model That Integrates Mental Healthcare and Primary Care Using Telemedicine and Care Management for Patients With Depression or Alcohol Use Disorder in Small Primary Care ClinicsCompletedNCT027132171 country
- A Response Modulation Hypothesis of Socioemotional Processing Associated With Alcohol Use DisorderCompletedNCT03535129Not applicable1 country
- The Co-Venture Trial: A Cluster Randomized Trial of Personality-targeted Interventions on Adolescent Substance Use and Cognitive OutcomesCompletedNCT01655615Not applicable1 country
- Digital Treatments for Opioids and Other Substance Use Disorders in Primary CareCompletedNCT05160233Not applicable1 country
- Project QueST 2023: Queer Survivors of TraumaCompletedNCT05569915Not applicable1 country
- Game-Based Intervention to Reduce Alcohol-Related Harms Among Sexual and Gender Minority YouthTerminatedNCT06215664Not applicable1 country
- Addressing Barriers to Care for Substance Use Disorder TrialActive, not recruitingNCT06729957Not applicable1 country
- TeleHealth Resources for IndiVidualizEd Goals (THRIVE) in Alcohol Recovery StudyActive, not recruitingNCT06074341Not applicable1 country
- Semaglutide Therapy for Alcohol Reduction - TulsaCompletedNCT05891587Phase 21 country
- Endourage Complete Spectrum Oral Mucosal Drops (OMD) in Adults Desiring a Reduction in Ethanol UseWithdrawnNCT04659278Not applicable1 country
- An Initial Study of the Implementation of Digital Therapeutics for Substance Use Disorders in Primary CareCompletedNCT04907045Not applicable1 country
- Alcohol & Exercise StudyCompletedNCT05955911Not applicable1 country
- Psilocybin in Alcohol Use Disorder With Comorbid DepressionCompletedNCT06235411Not applicable1 country
- Remote Alcohol Monitoring and Episodic ThinkingCompletedNCT03340051Not applicable1 country
- Project VALOR: Veteran Stress and WellbeingTerminatedNCT06095817Not applicable1 country
- Manipulating Ghrelin Signaling Via GOAT Inhibition in Alcohol Use DisorderCompletedNCT03896516Phase 1/21 country