VA Office of Research and Development: Alcoholism trials

The registry lists 47 Alcoholism studies with VA Office of Research and Development as lead sponsor. 7 are open to participants now and 32 have results posted.

Early Phase 1 1Phase 1 4Phase 2 9Phase 3 5Phase 4 3No phase 28(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• PTSD and Alcohol Couples Treatment for VeteransNot yet recruitingNCT07388654Early Phase 1
• Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized Controlled Trial for Alcohol Use Disorder (CRAVE)RecruitingNCT07218354Phase 3
• MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use DisorderRecruitingNCT07118839Phase 2/3
• Non-invasive Vagal Nerve Stimulation as Novel Treatment to Improve Functional Outcomes in Veterans With Alcohol Use DisorderRecruitingNCT06399653Not applicable
• Combining a Smartphone App With Medications to Manage Heavy DrinkingRecruitingNCT06303778Not applicable
• AAT for Alcohol Use Disorder in VeteransRecruitingNCT05372029Not applicable
• rTMS Target Identification for Functional Disability in AUD+mTBIEnrolling by invitationNCT04043442Phase 2
• Non-invasive Vagal Nerve Stimulation in Alcohol Use DisorderCompletedNCT05226130Phase 1Results posted
• Stress, Emotion Regulation, and Alcohol in Women VeteransCompletedNCT04393623Not applicableResults posted
• HCV and Co-morbid Alcohol Use Disorders: A Translational Investigation of Antiviral Therapy Outcomes on CNS FunctionCompletedNCT03902366Results posted
• Pioglitazone for the Treatment of Alcohol Use DisorderCompletedNCT03864146Not applicableResults posted
• Impact of Modifiable Psychosocial Factors on Veterans' Long-term Trajectories of Functioning and Quality of LifeCompletedNCT03615222Results posted
• Neurobiology of Alcohol and Nicotine Co-AddictionCompletedNCT03338933Results posted
• Improving Outcomes Among Medical/Surgical Inpatients With Alcohol Use DisordersCompletedNCT03258632Not applicableResults posted
• Transcranial Magnetic Stimulation for the Treatment of Veterans With Alcohol Use DisordersCompletedNCT03191266Not applicableResults posted
• Topiramate and Prolonged ExposureCompletedNCT03176953Phase 2/3Results posted
• Topiramate Treatment of Alcohol Use Disorders in African AmericansTerminatedNCT03018704Phase 4Results posted
• Cognitive Remediation for Alcohol Use Disorder and Posttraumatic Stress DisorderCompletedNCT02929979Not applicableResults posted
• Implementing a Blended Care Model That Integrates Mental Healthcare and Primary Care Using Telemedicine and Care Management for Patients With Depression or Alcohol Use Disorder in Small Primary Care ClinicsCompletedNCT02713217Results posted
• Cognitive Training in the Treatment of AUDCompletedNCT02664038Not applicableResults posted
• CAP: Doxazosin in the Treatment of Co-Occurring PTSD and Alcohol Use DisordersCompletedNCT02500602Phase 2Results posted
• Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use DisorderCompletedNCT02461927Phase 1/2Results posted
• Effectiveness of Zonisamide in Alcohol Dependent VeteransTerminatedNCT02368431Phase 3Results posted
• Group Motivational Interviewing (GMI) For Homeless Veterans In VA ServicesCompletedNCT02233738Not applicableResults posted
• Relational Agent for Alcohol Screening and TreatmentCompletedNCT02030288Not applicableResults posted
• Examination of Zinc, S-adenosylmethionine, and Combination Therapy Versus Placebo in AlcoholicsCompletedNCT01899521Not applicableResults posted
• Web-based Intervention to Reduce Alcohol Use in Veterans With Hepatitis CCompletedNCT01707030Not applicableResults posted
• Helping Families Help Veterans With PTSD and Alcohol Abuse: An RCT of VA-CRAFTCompletedNCT01678196Not applicableResults posted
• Citalopram Effects on Craving and Dopamine Receptor Availability in AlcoholicsCompletedNCT01657760Phase 1Results posted
• Integrated Alcohol Disorder and PTSD TreatmentCompletedNCT01601067Phase 2Results posted
• Treatment Strategy for Alcohol Use Disorders in Veterans With TBICompletedNCT01342549Phase 3Results posted
• N-acetylcysteine Plus Naltrexone for the Treatment of Alcohol DependenceCompletedNCT01214083Phase 2Results posted
• Project SERVE: Post Deployment FunctioningCompletedNCT01123642Results posted
• Baclofen to Reduce Alcohol Use in Veterans With HCVCompletedNCT01008280Phase 4Results posted
• Couple-Based Treatment for Alcohol Use Disorders and Post-Traumatic Stress DisorderCompletedNCT00946322Phase 1Results posted
• Topiramate to Aid Smoking Cessation in Alcohol Dependent MenCompletedNCT00802412Phase 2Results posted
• Impact of Group Motivational Interviewing and In-Home-Messaging-Devices for Dually Diagnosed VeteransCompletedNCT00706901Not applicableResults posted
• LINK: Aftercare Monitoring ProjectCompletedNCT00265512Not applicableResults posted
• Health Focused Motivational Treatment for Alcohol Dependent VeteransCompletedNCT00252590Not applicableResults posted
• Personalized Approach Bias Modification in Heavy Drinking Veterans With Mild to Moderate Traumatic Brain InjuryWithdrawnNCT06380985Not applicable
• Stand Down-Think Before You Drink: An RCT of a Mobile App for Hazardous Drinking With Peer Phone SupportActive, not recruitingNCT05473598Not applicable
• CRP and S&A for Inpatient VeteransActive, not recruitingNCT05054738Not applicable
• CBT-I Augmentation of Medication for Drinking in AUDTerminatedNCT04581603Phase 4
• Effects of tDCS Paired With Cognitive Training on Brain Networks Associated With Alcohol Use Disorder in VeteransCompletedNCT04574167Not applicable
• Improving Care for Unhealthy Alcohol Use in Primary CareCompletedNCT04565899Not applicable
• sTMS for Substance Use-disordered VeteransCompletedNCT04336293Not applicable
• Pilot rTMS for AUD+mTBIActive, not recruitingNCT03995173Phase 2