University of Pennsylvania: Alcoholism trials

The registry lists 28 Alcoholism studies with University of Pennsylvania as lead sponsor. 7 are open to participants now and 12 have results posted.

Early Phase 1 1Phase 2 16Phase 3 9Phase 4 5No phase 2(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Effects of Ketogenic Diet on Alcohol IntoxicationRecruitingNCT07602270Not applicable
• Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use DisorderRecruitingNCT06807918Phase 2/3
• Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use DisorderRecruitingNCT06559995Phase 2/3
• Effects of Ketone Supplementation on Acute Alcohol WithdrawalEnrolling by invitationNCT06173973Phase 2/3
• Naltrexone in AUD Reward DrinkersRecruitingNCT05028062Phase 4
• Relationship Between Brain and Heart Glucose Metabolism in Alcohol Use DisorderEnrolling by invitationNCT05015881Phase 2/3
• Ketone Ester Intervention in Alcohol Use DisorderRecruitingNCT04616781Phase 2/3
• Smartphone Based Continuing Care for AlcoholCompletedNCT02681406Not applicableResults posted
• A Randomized, Double-blind Placebo-Controlled Pharmacogenetic Study of Topiramate in European-American Heavy DrinkersCompletedNCT02371889Phase 2Results posted
• Topiramate to Reduce Heavy Drinking in HIV-Positive Heavy DrinkersTerminatedNCT01764685Phase 2Results posted
• Vigabatrin for Cocaine and Alcohol DependenceTerminatedNCT01335867Phase 2Results posted
• HBPL Study of the Impact of the NK1 Antagonist AprepitantCompletedNCT01176591Phase 2Results posted
• Human Behavioral Pharmacology Laboratory (HBPL) Study of Varenicline's Impact on Cocaine and Alcohol CravingCompletedNCT01151813Phase 2Results posted
• Understanding Treatment Response With Naltrexone Among White AlcoholicsCompletedNCT00817089Phase 4Results posted
• VIVITROL as a Treatment for Cocaine and Alcohol DependenceCompletedNCT00777062Phase 2Results posted
• Varenicline (Chantix™) for the Treatment of Alcohol DependenceCompletedNCT00705523Phase 2Results posted
• Seroquel for Frequent, Heavy DrinkersCompletedNCT00674765Phase 2Results posted
• Managing Alcoholism in People Who Do Not Respond to NaltrexoneCompletedNCT00115037Phase 4Results posted
• Treatment for Alcoholism and Post-Traumatic Stress Disorder (Naltrexone)CompletedNCT00006489Phase 4Results posted
• Imaging Inflammation With Alcohol Use Disorder: an [18F]NOS StudyActive, not recruitingNCT05885594Early Phase 1
• Ibudilast for Treating Alcohol Use DisorderActive, not recruitingNCT05414240Phase 2
• Brief Intervention for Problem Drinking and Partner ViolenceCompletedNCT01207258Phase 2
• Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence - 1CompletedNCT00218660Phase 3
• Effectiveness of Extended Telephone MonitoringCompletedNCT00194103Phase 3
• Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol DependenceCompletedNCT00167232Phase 3
• Combination of Disulfiram Plus Naltrexone to Treat Both Cocaine- and Alcohol-dependent Individuals - 1CompletedNCT00142844Phase 2
• Quetiapine Fumarate (Seroquel) for the Treatment of Alcohol Dependence.CompletedNCT00124059Phase 3
• Sertraline for Alcohol Dependence and DepressionCompletedNCT00004554Phase 4