An observational study in Acute Pain and Servical Disc Herniation, sponsored by Samsun University. Not yet recruiting. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2026-07-09.
Sponsored by Samsun University · Observational
The aim of this study is to evaluate the postoperative analgesic efficacy of the Serratus Posterior Superior Intercostal Plane Block (SPSIP block) in patients undergoing Anterior Cervical Discectomy and Fusion (ACDF) surgery and to compare the outcomes with those of patients who do not receive regional anesthesia.
Cervical disc disorders may lead to various signs and symptoms, including neck pain, radicular pain in the upper extremities, sensory disturbances, motor weakness, and functional impairment. Anterior cervical discectomy and fusion (ACDF) is a widely accepted surgical procedure for the treatment of cervical disc herniation and other degenerative cervical spine disorders. However, postoperative pain remains a significant concern and may adversely affect recovery and patient comfort.
A multimodal analgesic approach is commonly preferred for postoperative pain management following cervical spine surgery. The incorporation of regional anesthesia techniques may reduce opioid consumption and opioid-related adverse effects while facilitating earlier mobilization, shorter hospital stay, and improved patient satisfaction.
In patients undergoing ACDF surgery, the Serratus Posterior Superior Intercostal Plane Block (SPSIPB) has emerged as a promising regional anesthesia technique for postoperative pain control. This study aims to evaluate the postoperative analgesic efficacy of SPSIPB and compare postoperative outcomes between patients receiving SPSIPB and those managed without regional anesthesia.
876 studies on the registry are indexed under Acute Pain; 154 are open to participants now.
This study's planned enrollment of 66 is below the median of 150 across 113 observational studies indexed under Acute Pain.
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The study population will consist of adult patients aged 18-70 years with ASA physical status I-III who are scheduled to undergo elective anterior cervical discectomy and fusion (ACDF) surgery under general anesthesia at Samsun City Hospital. Eligible patients who provide written informed consent and meet the study inclusion criteria will be enrolled consecutively during the study period
Exclusion Criteria:
The Serratus Posterior Superior Intercostal Plane Block (SPSIPB) will be administered under ultrasound guidance 30 minutes before the induction of anesthesia for anterior cervical discectomy and fusion (ACDF) surgery.
Patients in the control group will not receive any regional anesthesia technique before surgery and will undergo anterior cervical discectomy and fusion (ACDF) surgery under standard general anesthesia. Postoperative pain management will be provided according to the institution's routine multimodal analgesia protocol.
Opioid consumption
Time frame: 24 hours
1. Opioid consumption
In the postoperative period, patients will be given opioids according to their pain density with a patient-controlled device, and the daily Morphine consumption in Patient Controlled Analgesia device will be collected and compared between groups.
Time frame: 24 hours
2. Perioperative pain intensity
Changes in the Numerical Rating Scale (NRS) will be recorded at rest and during movement. The participant's baseline NRS will be recorded, followed by measurements before and after neuraxial positioning and up to 24 hours post-surgery. The NRS is a unidimensional measure of pain intensity in adults. It is a segmented numerical version of the Visual Analog Scale (VAS) where the participant selects a whole number (0-10) that best represents the intensity of their pain. The 11-point numerical scale ranges from '0' representing one end of the pain spectrum (e.g. 'no pain') to '10' representing the other end (e.g. 'worst imaginable pain').
Time frame: 24 hours
Quality of recovery 15 scale
Postoperative Quality of Recovery 15 in Turkish scale. The QoR-15 (Quality of Recovery-15) questionnaire is a simple and practical tool used to assess postoperative recovery. It consists of 15 items, each scored on a numeric scale from 0 to 10, resulting in a total score ranging from 0 to 150. Based on the total score, postoperative recovery is categorized as follows: 136-150: Excellent recovery 122-135: Good recovery 90-121: Moderate recovery 0-89: Poor recovery
Time frame: 24 hours after surgery
Postoperative nausea and vomiting
Postoperative nausea and vomiting (PONV): During follow-up, patients who experience nausea or vomiting will be evaluated using a verbal descriptive PONV scale (0=None, 1=Mild nausea, 2=Moderate nausea, 3=Single episode of vomiting, 4=More than one episode of vomiting).
Time frame: 24 hours
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Samsun University