Drug
Yohimbine clinical trials
- studies test it
- 25
- open now
- 2
- in phase 3
- 1
- first study started
- 1996
Keep track of what changes. Save the Yohimbine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Combined with it in one product
Studies by the year they started
24 studies that test it; most in 2009 (2)
| Year | Studies |
|---|---|
| 1996 | 1 |
| 2002 | 1 |
| 2004 | 1 |
| 2005 | 1 |
| 2007 | 1 |
| 2009 | 2 |
| 2010 | 1 |
| 2012 | 2 |
| 2013 | 1 |
| 2014 | 1 |
| 2016 | 1 |
| 2017 | 1 |
| 2018 | 2 |
| 2021 | 1 |
| 2023 | 2 |
| 2024 | 2 |
| 2025 | 1 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 3
- Phase 1
- 6
- Phase 2
- 8
- Phase 3
- 1
- Phase 4
- 3
- No phase
- 5
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 1 · Other 24
Wayne State University (5) · University Medicine Greifswald (2) · Charite University, Berlin, Germany (2) · Florida State University (1) · Hospices Civils de Lyon (1) · Vanderbilt University Medical Center (1) · National Institute of Mental Health (NIMH) (1) · VA Office of Research and Development (1)
Often tested with
Tested in the same studies.
Hydrocortisone (6) · Clonidine (2) · Phenylephrine (1) · Isoproterenol (1) · Nitroprusside (1) · Propranolol (1) · Edrophonium (1) · Atropine (1)
Studies
Open first, then newest update. How each study uses Yohimbine is read from its arms, and is right about nine times in ten.
Testing it · 25
- Evaluation of Solanidine as an Exogenous Biomarker to Phenotype CYP2D6 Activity in HumansNot yet recruitingNot applicableUniversity Medicine GreifswaldNCT07817030Written as Yohimbine
- Effects of Pharmacological Stress and rTMS on Executive Function in Opioid Use DisorderNot yet recruitingPhase 2Wayne State UniversityNCT04231708Written as Yohimbine + Hydrocortisone
- Cannabinoids and Biological Reactivity to StressCompletedEarly Phase 1Florida State UniversityNCT06430580Written as Yohimbine Hydrochloride
- Kinetics of Yohimbine in Humans to Explore Sex and CYP2D6 Genotype InteractionsCompletedNot applicableUniversity Medicine GreifswaldNCT06939608Written as Yohimbine
- [11C]Yohimbine PET Study of alpha2-ARCompletedPhase 1Hospices Civils de LyonNCT03520543Written as [11C]Yohimbine
- Role Of Sensitivity to neuroEndocrine Systems in Social DecisionsWithdrawnPhase 4University of North Carolina, Chapel HillNCT06018727Written as Yohimbine
- Effects of Stress and Drug-cue Exposure (SCM)CompletedPhase 1Wayne State UniversityNCT03154567Written as Yohimbine
- The Role of the Noradrenergic System in the Nonmotor Symptoms of Parkinson's DiseaseWithdrawnEarly Phase 1Nathaniel M. RobbinsNCT04346394Written as Yohimbine HCl
- rTMS of Limbic Circuitry in Stress Modulation in Healthy VolunteersWithdrawnPhase 2Wayne State UniversityNCT04180969Written as yohimbine + hydrocortisone
- Using rTMS to Explore Neural Mechanisms of Stress-Induced Opioid UseWithdrawnPhase 2Wayne State UniversityNCT04181515Written as Yohimbine + Hydrocortisone
- The Pathophysiology of Orthostatic HypotensionCompletedPhase 1Vanderbilt University Medical CenterNCT00748059Written as clonidine,yohimbine,metoclopramide,alpha-methyldopa
- Rapid Antidepressant Effects of Yohimbine in Major DepressionCompletedPhase 2National Institute of Mental Health (NIMH)NCT00078715Written as Yohimbine hydrochloride
- Effects of Melatonin to Reduce Nocturnal Hypertension in Patients With Neurogenic Orthostatic HypotensionTerminatedEarly Phase 1London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph'sNCT02963181Written as Yohimbine
- Noradrenergic Activity, Cognition and Major Depressive DisorderCompletedNot applicableCharite University, Berlin, GermanyNCT02470026Written as yohimbine
- Investigation of Nicotine Seeking Behavior in Current SmokersCompletedPhase 1Wayne State UniversityNCT03670212Written as Yohimbine Hydrochloride
- Prolonged Exposure for Post Traumatic Stress Disorder (PTSD) With/Without YohimbineCompletedPhase 2VA Office of Research and DevelopmentNCT01031979Written as Yohimbine
- The Effect of Yohimbine on Cocaine Cue ReactivityCompletedPhase 2Medical University of South CarolinaNCT00535002Written as Yohimbine
- Treatment of Orthostatic Hypotension in Autonomic FailureCompletedPhase 1Vanderbilt UniversityNCT00223691Written as Yohimbine
- Influence of the Noradrenergic System on the Formation of Intrusive MemoriesCompletedNot applicableCharite University, Berlin, GermanyNCT02541071Written as Yohimbine
- Bioequivalence Study Comparing Two Test Products With One Reference Product, All Containing 5 mg YohimbineCompletedPhase 4Walter Ritter GmbH & CoNCT00975325Written as Yohimbine
See all 25 studies that test Yohimbine →
Given in every arm · 1 — Yohimbine is usual care beside what is tested
Codes
What other systems call Yohimbine · ClinicalTrials.gg INT008427
- MeSH (NLM) D015016YohimbineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 2Y49VWD90QYOHIMBINEConfirmed FDA, NLM, Wikidata
- RxNorm 220982Confirmed FDA, Wikidata
- Wikidata Q412226yohimbineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C77304YohimbineOne source FDA
- DrugBank DB01392One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D015016 | Yohimbine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 2Y49VWD90Q | YOHIMBINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 220982 | — | Confirmed FDA, Wikidata |
| Wikidata | Q412226 | yohimbine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C77304 | Yohimbine | One source FDA |
| DrugBank | DB01392 | — | One source Wikidata |
Also registered as corynanthine (UNII F5Z7C9RK8U), corynanthine tartrate (UNII 7359P0A2QF) and yohimbine hydrochloride (UNII NB2E1YP49F · RxNorm 133041).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.