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Borderline Personality Disorder clinical trials

The registry lists 278 studies for Borderline Personality Disorder across more than 10 countries. 70 are recruiting or about to start. 232 of them are mainly about Borderline Personality Disorder (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.

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Status

Completed
142
Recruiting
49
Status unknown
35
Not yet recruiting
17
Active, not recruiting
11
Terminated
10

Phase

Phase 2
29
Phase 1
11
Phase 3
10
Phase 4
7
Early Phase 1
1

Where

United States
81
Germany
37
France
32
Canada
24
Spain
19
Denmark
10

Who runs them

University Hospital, Montpellier (8) · University of Minnesota (7) · Centre for Addiction and Mental Health (6) · Icahn School of Medicine at Mount Sinai (5) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (5) · University Hospital, Toulouse (5) · University Hospital, Strasbourg, France (5) · Yale University (5)

What is being tested here

Drugs under test in Borderline Personality Disorder studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Psilocybin102
Methylphenidate102
Ketamine102
N-Methyl-3,4-methylenedioxyamphetamine101
Cycloserine101
Brexpiprazole013
Oxytocin003
Olanzapine023
Quetiapine023
Fluoxetine002

Drug classes tested here Psychedelics 2 open · Antipsychotics 8 · SSRIs 4 · Opioid antagonists 3

Coming up

0phase 3 studies under way
22studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest

Who these studies take

Of the 49 Borderline Personality Disorder studies recruiting now, 18 (37%) set no upper age limit and 30 (61%) stop at 75 or younger. 8 (16%) take children under 18. 3 (6%) are for women only and 0 (0%) for men only; 11 (22%) take healthy volunteers.

Recruiting studies that take each age, of 49
AgeWomenMen
101 (2%)1 (2%)
1845 (92%)43 (88%)
3043 (88%)42 (86%)
4043 (88%)42 (86%)
5042 (86%)41 (84%)
6533 (67%)33 (67%)
7519 (39%)19 (39%)
8518 (37%)18 (37%)

Across all 278 studies, recruiting or not: 73% stop at 75 or younger and 71% at 65; 15% take children; 13% are for women only and 1% for men only; 26% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Borderline Personality Disorder studies take

Of 107 interventional studies with no phase under Borderline Personality Disorder, half reached primary completion within 35 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase35 mo24–54 · 107 studies—35 mo24–54 · 105 studies
Observational37 mo23–119 · 19 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting1

Results posted1

Newly registered2

Studies

Recruiting first, then most recently updated. Showing 50 of 278. Browse all 278 → or search them.