Drug
Pentoxifylline clinical trials
Also written Trental and Pentoxil.
- studies test it
- 145
- open now
- 25
- in phase 3
- 33
- first study started
- 1995
Keep track of what changes. Save the Pentoxifylline studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Studies by the year they started
143 studies that test it; most in 2022 (15)
| Year | Studies |
|---|---|
| 1995 | 2 |
| 1996 | 1 |
| 1999 | 1 |
| 2000 | 2 |
| 2001 | 1 |
| 2002 | 4 |
| 2003 | 2 |
| 2004 | 3 |
| 2005 | 4 |
| 2006 | 6 |
| 2008 | 2 |
| 2009 | 8 |
| 2010 | 5 |
| 2011 | 5 |
| 2012 | 5 |
| 2013 | 5 |
| 2014 | 1 |
| 2015 | 5 |
| 2016 | 3 |
| 2017 | 4 |
| 2018 | 4 |
| 2019 | 6 |
| 2020 | 8 |
| 2021 | 5 |
| 2022 | 15 |
| 2023 | 14 |
| 2024 | 8 |
| 2025 | 11 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 9
- Phase 1
- 13
- Phase 2
- 62
- Phase 3
- 33
- Phase 4
- 22
- No phase
- 27
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 3 · Other 142
Tanta University (14) · Ain Shams University (8) · University Health Network, Toronto (5) · National Taiwan University Hospital (5) · Mansoura University (4) · Institute of Liver and Biliary Sciences, India (4) · Beni-Suef University (3) · M.D. Anderson Cancer Center (3)
Often tested with
Tested in the same studies.
Vitamin E (8) · Tocopherols (5) · Ursodeoxycholic Acid (3) · Tadalafil (2) · Zinc Sulfate (2) · Sildenafil (2) · Pravastatin (2) · Folic Acid (1)
Studies
Open first, then newest update. How each study uses Pentoxifylline is read from its arms, and is right about nine times in ten.
Testing it · 145
- Pentoxifylline Add-On Therapy for Mild-to-Moderate Plaque PsoriasisNot yet recruitingNot applicableWasuchon ChaichanNCT07626788Written as Pentoxifylline 400 mg Oral Tablet
- Pentoxifylline as Anti-Inflammatory in Patients With Rheumatoid ArthritisRecruitingPhase 2Tanta UniversityNCT06998628Written as Pentoxifylline
- Systemic Therapy of Open-label Prophylactic Pravastatin or Pentoxifylline/Tocopherol Prevention of Lymphedema Advancing to Eventual Fibrosis: an Interventional Registry-embedded Bayesian Randomized Trial for Radiation Sequelae (STOP4-LATE-FIBROSE)RecruitingPhase 2M.D. Anderson Cancer CenterNCT06494111Written as Pentoxifylline
- Pneumonitis Prevention Protocol Using Pentoxifylline and α-tocopherol In Stage III Non-Small Cell Lung Cancer Patients Undergoing ChemoradiationRecruitingPhase 2University Health Network, TorontoNCT06634056Written as Pentoxifylline
- Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomized-controlled Orphan Drug Platform Trial for Orodental Sequelae (Reverse-fibrose)RecruitingPhase 2M.D. Anderson Cancer CenterNCT06912763Written as Pentoxifylline
- The PENTO Protocol in Medication-related Osteonecrosis of the JawRecruitingPhase 2University Hospital, LimogesNCT05795647Written as Pentoxifylline+Tocopherol
- Cocaine and Pentoxifylline (BED IN 47)RecruitingEarly Phase 1William StoopsNCT07086794Written as Pentoxifylline
- Pentoxifylline in Patients With Ulcerative ColitisRecruitingPhase 2Ihab Elsayed HassanNCT07349472Written as Pentoxifylline
- Effect of Pentoxyfilline on Endometrial Thickness and Frozen Embryo Transfer OutcomesRecruitingPhase 3Beni-Suef UniversityNCT07499817Written as pentoxifylline 400 mg
- Effect of Pentoxifylline + CoQ10 vs CoQ10 Alone on Sperm Motility in Subfertile Men With AsthenozoospermiaRecruitingNot applicableMst.Sumyara KhatunNCT07252518Written as Pentoxifylline 400 MG Oral Tablet
- Nephroprotection Following Perinatal Asphyxia: Randomized Controlled TrialNot yet recruitingNot applicableAlexandria UniversityNCT07088328Written as Pentoxifylline
- To Study Effect of Injection Pentoxifylline on Liver Growth After Major Liver SurgeryRecruitingNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT07085806Written as Pentoxifylline (also known as oxpentifylline)
- Pentoxifylline for Vascular Calcification in Kidney DiseaseNot yet recruitingPhase 1/2Mansoura UniversityNCT06903689Written as Pentoxifylline 400 MG Oral Tablet
- Bioequivalence Study of Pentoxifylline 400 Mg in Healthy Subjects Under Fasting and Fed ConditionsNot yet recruitingPhase 4Centro de Atencion e Investigacion MedicaNCT06823362Written as Pentoxifylline
- Renoprotective Effects of Dapagliflozin Versus Pentoxiphylline in Chronic Kidney Disease PatientsRecruitingPhase 3Ain Shams UniversityNCT06421870Written as Pentoxifylline 400 MG
- Effect of Pentoxifylline on Cognitive Impairment After Ischemic StrokeRecruitingPhase 1/2The First Hospital of Hebei Medical UniversityNCT06344390Written as Pentoxifylline
- Efficacy of Intralesional Injection of Pentoxifylline, Platelet-Rich Plasma, and Combined Pentoxifylline With Platelet-Rich Plasma in Patients With Atrophic Acne ScarsRecruitingNot applicableSohag UniversityNCT06319768Written as Pentoxifylline
- Safety of Pentoxifylline and Vitamin E With Stereotactic Ablative Radiotherapy (SABR) in Non-small Cell Lung CancersRecruitingPhase 2University of LouisvilleNCT01871454Written as Pentoxifylline
- Pentoxifylline as an Adjunct Therapy for Patients With Eisenmenger SyndromeRecruitingNot applicableUniversity of Sao Paulo General HospitalNCT05611268Written as Pentoxifylline
- Topical Pentoxifylline; Metformin Versus Betamethasone in the Treatment of Alopecia Areata.Not yet recruitingPhase 1Assiut UniversityNCT06087796Written as Pentoxifylline
See all 145 studies that test Pentoxifylline →
Given in every arm · 2 — Pentoxifylline is usual care beside what is tested
- The Association of Miltefosine and Pentoxifylline to Treat Mucosal and Cutaneous Leishmaniasis: A Clinical Trial in BrazilActive, not recruitingPhase 2University of BrasiliaNCT02530697Written as Pentoxifylline
- Clinical Benefit of Spa Care on Severe Radiation-induced Fibrosis After Postoperative Radiotherapy for Breast CancerStatus unknownPhase 3Institut de Cancérologie de LorraineNCT02898376Written as Pentoxifylline
As the comparator · 12 — what is tested is compared with Pentoxifylline
- Clinical Study Evaluating Safety of Pentoxifylline and Celecoxib in Patients With Grand-Mal Epilepsy Treated by Phenytoin MonotherapyRecruitingPhase 2Mostafa BahaaNCT05637086Written as Pentoxifylline 400 MG
- Efficacy, Satisfaction, and Safety of the Mesolipo® Protocol for the Treatment of Localized AdiposityCompletedNot applicableAntony de Paula BarbosaNCT07743788Written as Pentoxifylline
- Impact of Curcumin and Pentoxiphylline on Chronic Kidney Disease PatientsCompletedNot applicableAlexandria UniversityNCT06458465Written as Pentoxifylline 400 MG
- Metformin Repurposing in Oral Submucous Fibrosis: Unveiling In Vitro Signaling Pathways, Progressing to Clinical TrialCompletedPhase 1/2Ziauddin UniversityNCT06332612Written as Pentoxifylline
- Acute Post-Radiation Hyperbaric Oxygen (HBO2) for Breast Cancer Patients Who Have Recently Completed Radiation TherapyTerminatedPhase 2Legacy Health SystemNCT03916068Written as Trental Pill
- Evaluate the Effect and Safety of Pu Yang Wan Wu Tang and Western Medicine on Chronic Kidney DiseaseStatus unknownPhase 2/3Taipei Medical University HospitalNCT05387187Written as Pentoxifylline
- Study to Evaluate the PK of Single and Optional Multiple Dosing Regimens of MR Formulations of PCS499 Compared to Trental® Administered to Healthy SubjectsCompletedPhase 1Processa PharmaceuticalsNCT03836222Written as Trental
- Renoprotection by Pentoxifylline and Angiotensin Receptor Blocker in Chronic Kidney Disease (CKD)Status unknownPhase 4National Taiwan University HospitalNCT01377285Written as Pentoxifylline
- Prostaglandin E1 in Outpatients With Intermittent ClaudicationCompletedPhase 3UCB PharmaNCT01263925Written as Pentoxifylline
- Efficacy of Pentoxifylline and Rifaximin Combination in Pentoxifylline Refractory Clinical and Subclinical Hepatopulmonary SyndromeStatus unknownNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT01676597Written as pentoxifylline and rifaximin
- Treatment of Radiation-induced Fibrosis in the Upper Aerodigestive Tract Cancer by a Combination of Pentoxifylline-tocopherol and Hyperbaric OxygenStatus unknownPhase 2Hospital Universitario de CanariasNCT01822405Written as pentoxifylline with tocopherol
- Pentoxifylline Versus Pioglitazone In Non-Alcoholic Steatohepatiti (NASH)Status unknownNot applicableGovind Ballabh Pant HospitalNCT00681733Written as Pentoxifylline
Codes
What other systems call Pentoxifylline · ClinicalTrials.gg INT007976
- MeSH (NLM) D010431PentoxifyllineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) SD6QCT3TSUPENTOXIFYLLINEConfirmed FDA, NLM, Wikidata
- RxNorm 8013Confirmed FDA, Wikidata
- Wikidata Q416331pentoxifyllineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C733PentoxifyllineOne source FDA
- DrugBank DB00806One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D010431 | Pentoxifylline | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | SD6QCT3TSU | PENTOXIFYLLINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 8013 | — | Confirmed FDA, Wikidata |
| Wikidata | Q416331 | pentoxifylline | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C733 | Pentoxifylline | One source FDA |
| DrugBank | DB00806 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.