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Non-alcoholic Fatty Liver Disease clinical trials

The registry lists 1,618 studies for Non-alcoholic Fatty Liver Disease across more than 10 countries. 323 are recruiting or about to start. 1,253 of them are mainly about Non-alcoholic Fatty Liver Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.

ClinicalTrials.gov finds 1,709 studies for Non-alcoholic Fatty Liver Disease. How that becomes 1,617 here

This page counts the studies the registry files under Non-alcoholic Fatty Liver Disease, and those it files under no condition that list Non-alcoholic Fatty Liver Diseasethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 1,709Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −5List Non-alcoholic Fatty Liver Disease as a condition, but the registry did not file them under itMost often written as “Non-alcoholic Fatty Liver Disease NAFLD” (2), “NAFLD - Non-Alcoholic Fatty Liver Disease” (1), and “Non-alcoholic Fatty Liver Diseases” (1). The registry filed them under other conditions only, most often Fatty Liver (2) and Diabetes Mellitus, Type 2 (1).
  3. −89Match it another way54 name it in the title, 2 in a keyword, and 33 by a synonym or other text the search reads.
  4. 1,615Counted here and found by its search14 of them list Non-alcoholic Fatty Liver Disease in their own words; the registry filed them under no condition.
  5. +2
    Counted here, but its search does not find them
  6. 1,617The count on this page

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Status

Completed
845
Status unknown
220
Recruiting
220
Terminated
94
Active, not recruiting
89
Not yet recruiting
82

Phase

Phase 2
351
Phase 1
181
Phase 3
92
Phase 4
80
Early Phase 1
15

Where

United States
547
China
142
United Kingdom
122
France
104
Italy
99
Canada
91

Who runs them

Assiut University (25) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (20) · Massachusetts General Hospital (16) · Gilead Sciences (16) · AstraZeneca (15) · Cairo University (15) · Pfizer (15) · University of California, San Diego (14)

What is being tested here

Drugs under test in Non-alcoholic Fatty Liver Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Pioglitazone4319
Semaglutide4216
Empagliflozin4116
Efimosfermin alfa324
Liraglutide206
Pegozafermin225
Tirzepatide213
ECC0509203
ECC4703203
Mazdutide202

Drug classes tested here GLP-1 receptor agonists 6 open · SGLT2 inhibitors 5 open · Statins 3 open · DPP-4 inhibitors 8 · Androgens 4

Coming up

23phase 3 studies under way
90studies finish main data collection within a year5 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 220 Non-alcoholic Fatty Liver Disease studies recruiting now, 66 (30%) set no upper age limit and 125 (57%) stop at 75 or younger. 27 (12%) take children under 18. 8 (4%) are for women only and 2 (1%) for men only; 55 (25%) take healthy volunteers.

Recruiting studies that take each age, of 220
AgeWomenMen
1021 (10%)21 (10%)
18180 (82%)178 (81%)
30184 (84%)181 (82%)
40195 (89%)191 (87%)
50192 (87%)191 (87%)
65178 (81%)177 (80%)
75138 (63%)136 (62%)
8576 (35%)75 (34%)

Across all 1,618 studies, recruiting or not: 63% stop at 75 or younger and 33% at 65; 11% take children; 2% are for women only and 3% for men only; 25% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Non-alcoholic Fatty Liver Disease studies take

Of 185 phase 2 interventional studies under Non-alcoholic Fatty Liver Disease, half reached primary completion within 26 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 110 mo5–21 · 125 studies10 mo4–16 · 104 studies—
Phase 1/223 mo16–36 · 21 studies——
Phase 226 mo16–36 · 185 studies22 mo15–30 · 132 studies40 mo25–56 · 53 studies
Phase 336 mo25–61 · 34 studies——
Phase 425 mo13–46 · 44 studies—25 mo13–46 · 41 studies
Interventional, no phase25 mo12–48 · 385 studies19 mo10–27 · 28 studies26 mo12–51 · 357 studies
Observational49 mo25–124 · 170 studies—55 mo29–125 · 159 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 15, 2026.

Started recruiting2

Results posted2

Newly registered7

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Studies

Recruiting first, then most recently updated. Showing 50 of 1,618. Browse all 1,618 → or search them.