Hyperbilirubinemia, Neonatal clinical trials
The registry lists 96 studies for Hyperbilirubinemia, Neonatal across more than 10 countries. 20 are recruiting or about to start. 63 of them are mainly about Hyperbilirubinemia, Neonatal (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-25. Counting its narrower condition Jaundice, Neonatal too: 177 studies, 39 open.
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Who runs them
InfaCare Pharmaceuticals Corporation, a Mallinckrodt Company (5) · University of Aarhus (4) · Nanjing Medical University (4) · University of Oxford (3) · National Taiwan University Hospital (2) · University of Patras (2) · St. Olavs Hospital (2) · Karabuk University (2)
What is being tested here
Drugs under test in Hyperbilirubinemia, Neonatal studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 8, phase 3 first
- Nov 2027Newborn Jaundice - An Investigation of Different Approaches to Light Therapy · Phase 3 · Regionshospital Nordjylland
- Dec 2026The Effect of Kangaroo Care on Pain in Infants Receiving Phototherapy · Marmara University
- Dec 2026Transcutaneous Bilirubinometry and Phototherapy · Princess Amalia Children's Clinic
- Dec 2026Modified Diagnosis and Treatment of Neonatal Hemolysis With ETCOc in sNH · Women's Hospital School Of Medicine Zhejiang University
- Jan 2027The Efficacy of Ursodeoxycholic Acid (UDCA) as Adjuvant Therapy to Phototherapy in the Management of Neonatal Indirect Hyperbilirubinemia · Tishreen University Hospital
- Mar 2027Foot Reflexology and Massage in Neonates Receiving Phototherapy · Aydin Adnan Menderes University
- Aug 2027Paternal Involvement in Nursing Guidance and Breastfeeding Self-Efficacy in Mothers of High-Risk Newborns · Taipei Medical University Shuang Ho Hospital
- Aug 2027Bilirubin Thresholds in Preterm Infants on Neonatal Intensive CarE Units: The B-NICE Trial · University Medical Center Groningen
Who these studies take
Of the 14 Hyperbilirubinemia, Neonatal studies recruiting now, 0 (0%) set no upper age limit and 14 (100%) stop at 75 or younger. 13 (93%) take children under 18. 1 (7%) are for women only and 0 (0%) for men only; 7 (50%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 1 (7%) | 0 (0%) |
| 30 | 1 (7%) | 0 (0%) |
| 40 | 1 (7%) | 0 (0%) |
| 50 | 0 (0%) | 0 (0%) |
| 65 | 0 (0%) | 0 (0%) |
| 75 | 0 (0%) | 0 (0%) |
| 85 | 0 (0%) | 0 (0%) |
Across all 96 studies, recruiting or not: 90% stop at 75 or younger and 90% at 65; 94% take children; 5% are for women only and 0% for men only; 38% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hyperbilirubinemia, Neonatal studies take
Of 34 interventional studies with no phase under Hyperbilirubinemia, Neonatal, half reached primary completion within 10 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 10 mo6–21 · 34 studies | — | 10 mo6–21 · 34 studies |
| Observational | 20 mo6–59 · 15 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 96. Browse all 96 → or search them.
- Foot Reflexology and Massage in Neonates Receiving PhototherapyRecruitingNCT07610811Not applicable1 country
- The Effect of Kangaroo Care on Pain in Infants Receiving PhototherapyRecruitingNCT07761689Not applicable1 country
- Hat-Type Glasses Intervention in Phototherapy-Related NewbornsEnrolling by invitationNCT07690930Not applicable1 country
- Predictors of Rebound Hyperbilirubinemia StudyNot yet recruitingNCT076946351 country
- Bilirubin Thresholds in Preterm Infants on Neonatal Intensive CarE Units: The B-NICE TrialNot yet recruitingNCT07674537Not applicable1 country
- The Efficacy of Ursodeoxycholic Acid (UDCA) as Adjuvant Therapy to Phototherapy in the Management of Neonatal Indirect HyperbilirubinemiaRecruitingNCT07110987Not applicable1 country
- Modified Diagnosis and Treatment of Neonatal Hemolysis With ETCOc in sNHRecruitingNCT06832800Early Phase 11 country
- Investigation Into the Dynamic Variations of End-Tidal Carbon Monoxide Concentration (ETCOc) in Neonates Utilizing Non-Dispersive Infrared Spectroscopy and Its Implications for Jaundice ManagementRecruitingNCT07346976Not applicable1 country
- Newborn Jaundice - An Investigation of Different Approaches to Light TherapyRecruitingNCT06702241Phase 2/31 country
- Predictive and Diagnostic Value of BIND Score in Assessment of Severe Neonatal Jaundice Cases in Neonatal Intensive Care UnitNot yet recruitingNCT07150494
- Safe Threshold to Discontinue Phototherapy in Hemolytic Disease of NewbornRecruitingNCT04218318Not applicable1 country
- Role of Serum (B/A) Ratio Compared to (TSB) for Early Prediction of Bilirubin-induced Neurological Dysfunction (BIND).Not yet recruitingNCT06603753
- Transcutaneous Bilirubinometry and PhototherapyNot yet recruitingNCT04246229Not applicable1 country
- Validation of a Jaundice Diagnostic and Monitoring Device for Low-Resource SettingsRecruitingNCT038662132 countries
- Preventive Effect of Perinatal Oral Probiotic Supplementation (POPS) on Neonatal JaundiceRecruitingNCT06087874Phase 21 country
- Evaluation of Bilirubin Estimates in Newborns From Smartphone Digital Images in a Population in BotswanaRecruitingNCT06399146Not applicable1 country
- Prediction and Evaluation by ETCOc of Neonatal Hyperbilirubinemia CohortRecruitingNCT063415821 country
- Hyperbilirubinemia in Full-term NeonatesRecruitingNCT06238349Phase 41 country
- The Effect and Mechanism of Gene Variation on Neonatal HyperbilirubinemiaRecruitingNCT061863491 country
- Screening and Follow-up Study of Neonatal Jaundice Based on Mobile NetworkRecruitingNCT042512861 country
- Paternal Involvement in Nursing Guidance and Breastfeeding Self-Efficacy in Mothers of High-Risk NewbornsActive, not recruitingNCT07834008Not applicable1 country
- Effectiveness of Aluminum Foil vs White Linen Reflectors in Phototherapy for Neonatal HyperbilirubinemiaCompletedNCT07266246Not applicable1 country
- Efficacy & Safety of Oral Adjuvants to Phototherapy in Neonatal HyperbilirubinemiaCompletedNCT06517862Phase 41 country
- The Effects of Underrunning Water Bathing and Underrunning Water Bathing-Massage Combination on Bilirubin Levels in Term Newborns With HyperbilirubinemiaCompletedNCT07771985Not applicable1 country
- Evaluation of Bili-ruler, a Low-cost, Plastic Icterometer for Community-based Screening of Jaundice in NewbornsCompletedNCT066877464 countries
- Wireless Irradiance SEnsors During Neonatal PhototherapyActive, not recruitingNCT070576351 country
- White Cover & Massage Effects on Bilirubin and Phototherapy in ABO-Incompatible NewbornsCompletedNCT06921330Not applicable1 country
- Relationship Between Delayed Cord Clamping at Birth and Neonatal Bilirubin Levels in Parturients With a Prior Child Requiring Therapy for Neonatal JaundiceCompletedNCT03741803Not applicable1 country
- White Cover and Massage Impact on Bilirubin Levels and Phototherapy Duration in NewbornsCompletedNCT06209489Not applicable1 country
- White Reflective Drape in Phototherapy for Neonatal HyperbilirubinemiaCompletedNCT07156721Not applicable1 country
- TCB Self-Monitoring in Healthy Term and Near-Term NeonatesCompletedNCT066451581 country
- The Effect of Total Body Massage on Neonatal Jaundice in Preterm NeonatesCompletedNCT07106164Not applicable1 country
- Massage, Tub Bathing, and Sponge Bathing Effects on Neonatal Bilirubin and ComfortCompletedNCT07084987Not applicable1 country
- Accuracy of TcB Measurements During and After PhototherapyCompletedNCT070803981 country
- The Effect of Position Change Frequency on HyperbilirubinemiaCompletedNCT06324799Not applicable1 country
- Effect of Probiotic Lacobacillus Reuterii on Serum Bilirubin Levels in Preterm InfantsCompletedNCT06672406Not applicable1 country
- The Effect of Massage on the Bilirubin Level in Term Infants Receiving PhototherapyCompletedNCT05356273Not applicable1 country
- Effects of Oil and Dry Neonatal Massage on Hyperbilirubinemia and ComfortCompletedNCT06630689Not applicable1 country
- Parental Participation on the Neonatal Ward - the neoPARTNER StudyActive, not recruitingNCT053434031 country
- Tactile and Kinaesthetic Stimulation in Neonates With HyperbilirubinaemiaCompletedNCT05077787Not applicable1 country
- Effectiveness of Phototherapy With and Without ProbioticsCompletedNCT06173856Not applicable1 country
- Transcutaneous Bilirubin Levels From Covered SkinCompletedNCT061058791 country
- The Effect of Phototherapy Treatment on Oxygen Saturation Measurement in NewbornsCompletedNCT044942171 country
- MRA and ABR as Early Predictors of Bilirubin-Induced Neurologic Dysfunction in Full-term Jaundiced NeonatesCompletedNCT060180121 country
- The Efficacy of Oral Probiotics on Neonatal HyperbilirubinemiaStatus unknownNCT03876678Not applicable1 country
- A Light Emitting Diode (LED) Mattress for Phototherapy of Jaundiced NewbornsCompletedNCT037230051 country
- Study on Newborn Babies With a Yellow Skin Color (Neonatal Jaundice Study)CompletedNCT023617881 country
- Identification of Jaundice in Newborns Using SmartphonesCompletedNCT04182555Not applicable1 country
- Intelligent Follow-up of Neonatal Jaundice Based on Early Indicators and Internet CommunicationsStatus unknownNCT05365984Not applicable
- Bundling Gentle Body Massage Along With Regular Position Change Under PhototherapyCompletedNCT05260138Not applicable1 country