DrugSupplement
Thiamine clinical trials
Also written Vitamin B1 and Thiamin.
Includes 5 studies of Thiamine hydrochloride.
- studies test it
- 63
- open now
- 14
- in phase 3
- 9
- first study started
- 2003
Keep track of what changes. Save the Thiamine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
63 studies that test it; most in 2018 (14)
| Year | Studies |
|---|---|
| 2003 | 1 |
| 2004 | 1 |
| 2006 | 1 |
| 2008 | 1 |
| 2009 | 3 |
| 2010 | 3 |
| 2011 | 1 |
| 2012 | 2 |
| 2013 | 1 |
| 2014 | 4 |
| 2015 | 1 |
| 2016 | 1 |
| 2017 | 3 |
| 2018 | 14 |
| 2019 | 5 |
| 2020 | 3 |
| 2021 | 3 |
| 2023 | 3 |
| 2024 | 5 |
| 2025 | 3 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 3
- Phase 1
- 6
- Phase 2
- 18
- Phase 3
- 9
- Phase 4
- 10
- No phase
- 19
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 3 · Other 60
Beth Israel Deaconess Medical Center (8) · Universitas Sumatera Utara (2) · Hamilton Health Sciences Corporation (2) · Daewoong Pharmaceutical Co. LTD. (2) · Baystate Medical Center (2) · University of California, Los Angeles (2) · University of California, San Francisco (1) · Spectrum Health - Lakeland (1)
Often tested with
Tested in the same studies.
Ascorbic Acid (14) · Hydrocortisone (4) · Omega-3 fatty acid (2) · Magnesium (2) · Taurine (2) · Riboflavin (2) · Thioctic Acid (2) · Ursodeoxycholic Acid (2)
Studies
Open first, then newest update. How each study uses Thiamine is read from its arms, and is right about nine times in ten.
Testing it · 63
- Comparative Study of Combination Treatment of Bionerv E+ Versus Vitamin B Complex in Treatment of Diabetic Polyneuropathy in Type 2 Diabetic Patients and Its Effect on Wound HealingRecruitingNot applicableBREGO Life SciencesNCT07877948Written as Alpha-Lipoic Acid, Vitamin B1, Vitamin B6, Vitamin B12, Vitamin E
- THiamine for Recovery In Vulnerable Early-life InfectionsNot yet recruitingPhase 2Milton S. Hershey Medical CenterNCT07868679Written as thiamine hydrochloride 100 mg
- COLchicine and Thiamine in Heart Failure Due to Ischemic Heart DiseaseRecruitingPhase 3Hamilton Health Sciences CorporationNCT05873881Written as Thiamine Mononitrate 300 mg
- Study on Thiamine Supplementation to REduce braiN Injury Associated With Chronic Alcohol Use in Outpatients With Alcohol Use DisorderNot yet recruitingPhase 2Institut National de la Santé Et de la Recherche Médicale, FranceNCT07844720Written as Thiamine
- Oral Thiamine (Vitamin B1) for Depression in Children and AdolescentsNot yet recruitingPhase 2Massachusetts General HospitalNCT07793071Written as thiamine hydrochloride 100 mg
- Thiamine Intervention and Coronary Artery Bypass GraftingRecruitingEarly Phase 1University of California, Los AngelesNCT06326996Written as Thiamine
- Affect of Melatonin on Sleep and Cognition in CirrhosisRecruitingNot applicableWeill Medical College of Cornell UniversityNCT07046429Written as Thiamine
- Effectiveness of Neuroplasticity-Targeted Supplements on Neuroinflammatory Markers, ADHD Symptom Severity, and Clinical Scores in ChildrenRecruitingNot applicableKhyber Medical University PeshawarNCT07665658Written as Thiamine
- Efficacy of Early Intravenous High-dose Vitamin C in Post-cardiac Arrest Shock.RecruitingPhase 2Centre Hospitalier de BethuneNCT05817851Written as Vitamin C (Laroscorbine) + Vitamin B1 (Bevitine)
- Efficacy of Vitamin B1 in Familial Adenomatous Polyposis Patients.Enrolling by invitationNot applicableShanghai Zhongshan HospitalNCT06649825Written as Vitamin B1
- Type 2 Diabetes and Blood Brain Barrier ImprovementRecruitingEarly Phase 1University of California, Los AngelesNCT06322212Written as Thiamine
- Glycine and Magnesium+Thiamine for the Treatment of Primary Ciliary DyskinesiaRecruitingNot applicableInstituto Nacional de Enfermedades RespiratoriasNCT06959251Written as Magnesium+thiamine
- Dose-dependent Kinetics of Thiamin in Healthy Volunteers with and Without Functional OCT1 Hepatic TransportersEnrolling by invitationNot applicableUniversity Medicine GreifswaldNCT06122701Written as Thiamin i.v.
- the Effect of Vitamin B 1 on Menstrual Pattern After Insertion of the IUD.Not yet recruitingPhase 3Beni-Suef UniversityNCT05971680Written as VITAMIN B1 500mg
- Thiamine, Ascorbic Acid, and Their Combination on MMP-9/TIMP-1 and Inflammatory Balance in SepsisCompletedNot applicableUniversitas Sumatera UtaraNCT07786350Written as Thiamine
- Thiamine as Adjunctive Therapy for Diabetic KetoacidosisCompletedPhase 2Beth Israel Deaconess Medical CenterNCT03717896Written as 200mg IV thiamine in 50mL 0.9% saline
- The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart DiseaseCompletedEarly Phase 1Universitas Sumatera UtaraNCT06298344Written as Thiamine
- Thiamine vs. Placebo to Increase Oxygen Consumption After Cardiac ArrestTerminatedPhase 2Beth Israel Deaconess Medical CenterNCT02974257Written as Thiamine
- The Effect of SLC19A3 Inhibition on the Pharmacokinetics of ThiamineCompletedPhase 4University of California, San FranciscoNCT03746106Written as Vitamin B1
- Thiamine, Vitamin C and Hydrocortisone in the Treatment of Septic ShockCompletedNot applicableSpectrum Health - LakelandNCT03540628Written as Thiamine and Vitamin C
See all 63 studies that test Thiamine →
Given in every arm · 1 — Thiamine is usual care beside what is tested
As the comparator · 1 — what is tested is compared with Thiamine
Codes
What other systems call Thiamine · ClinicalTrials.gg INT008303
- MeSH (NLM) D013831ThiamineConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) X66NSO3N35THIAMINEConfirmed FDA, NLM, Wikidata
- RxNorm 10454Confirmed FDA, Wikidata
- Wikidata Q27115611thiamine(1+) chlorideConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C874ThiamineConfirmed FDA, Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D013831 | Thiamine | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | X66NSO3N35 | THIAMINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 10454 | — | Confirmed FDA, Wikidata |
| Wikidata | Q27115611 | thiamine(1+) chloride | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C874 | Thiamine | Confirmed FDA, Wikidata |
Also registered as thiamine mononitrate (UNII 8K0I04919X · RxNorm 10456).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.