Drug
Sitagliptin clinical trials
Also written Januvia and MK0431.
- studies test it
- 313
- open now
- 12
- in phase 3
- 92
- first study started
- 2003
Keep track of what changes. Save the sitagliptin studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
- Sitagliptin
- 194
Development codes
- MK0431
- 31
Studies by the year they started
312 studies that test it; most in 2008 (35)
| Year | Studies |
|---|---|
| 2003 | 1 |
| 2004 | 7 |
| 2005 | 4 |
| 2006 | 14 |
| 2007 | 18 |
| 2008 | 35 |
| 2009 | 27 |
| 2010 | 33 |
| 2011 | 20 |
| 2012 | 22 |
| 2013 | 19 |
| 2014 | 14 |
| 2015 | 20 |
| 2016 | 21 |
| 2017 | 5 |
| 2018 | 5 |
| 2019 | 6 |
| 2020 | 7 |
| 2021 | 6 |
| 2022 | 3 |
| 2023 | 3 |
| 2024 | 7 |
| 2025 | 6 |
| 2026 | 9 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 46
- Phase 2
- 44
- Phase 3
- 92
- Phase 4
- 102
- No phase
- 39
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 125 · Other 188
Merck Sharp & Dohme LLC (77) · AstraZeneca (8) · Emory University (7) · Novo Nordisk A/S (5) · Ono Pharmaceutical Co. Ltd (5) · ADIUM (4) · University of Colorado, Denver (4) · Lund University (4)
Often tested with
Tested in the same studies.
Metformin (49) · Pioglitazone (11) · Dapagliflozin (10) · Glimepiride (8) · Empagliflozin (7) · Vildagliptin (7) · Saxagliptin (7) · Liraglutide (6)
Studies
Open first, then newest update. How each study uses sitagliptin is read from its arms, and is right about nine times in ten.
Testing it · 313
- Comparative Study Between (SGLT-2i) and (DPP-4i) in the Prevention of DICRecruitingPhase 4Tanta UniversityNCT07436663Written as Sitagliptin (DPP4 inhibitor)
- Disease-modifying Efficacy of Sitagliptin Therapy in Early-stage Parkinson's DiseaseNot yet recruitingPhase 2Yonsei UniversityNCT07804381Written as Sitagliptin
- A Phase 2 and Pharmacodynamic Study of Sitagliptin in Patients With Progressive Grade 4 GliomasRecruitingPhase 2Case Comprehensive Cancer CenterNCT07003542Written as Sitagliptin
- Sitagliptin With Pembro in RCC and MelanomaRecruitingPhase 1Fernando Maciel BarbosaNCT07634380Written as Sitagliptin
- Sun Yat-Sen Treatment Strategy for Enhancing Response in Muscle-invasive Bladder CancerRecruitingPhase 2Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityNCT07717242Written as Sitagliptin
- Sitagliptin in Recurrent/Progressive Grade 4 GliomaRecruitingPhase 1Kailin Yang, MD, PhDNCT07541781Written as Sitagliptin
- Neoadjuvant Chemotherapy, Anti-PD-1 Antibody and Sitagliptin for Locally Advanced pMMR CRCRecruitingPhase 1/2Second Affiliated Hospital, School of Medicine, Zhejiang UniversityNCT07365592Written as Sitagliptin (DPP4 inhibitor)
- Metformin, Empagliflozin With Sitagliptin vs Linagliptin in Type 2 DiabetesEnrolling by invitationPhase 4Bahria UniversityNCT07452913Written as Metformin+ Empagliflozin + Sitagliptin
- Effect of Add-on SGLT2i, TZD, or Combination Therapy in Type 2 Diabetes Patients on DPP4 InhibitorsNot yet recruitingPhase 4Yonsei UniversityNCT07108985Written as Sitagliptin 100 mg
- Sitagliptin or BeiDouGen Capsule Improve the Pregnancy Outcome in Patients with PCOSRecruitingNot applicablePeking University Third HospitalNCT06587698Written as Sitagliptin
- Sitagliptin for the Treatment of Type 2 DiabetesRecruitingPhase 4Beijing Chao Yang HospitalNCT04495881Written as Sitagliptin 100mg
- Effects of Sitagliptin in Relatives of T1D PatientsNot yet recruitingPhase 2/3University of MilanNCT05219409Written as Sitagliptin
- A Pilot Study Evaluating Safety of Sitagliptin Combined With Peg-IFN Alfa-2a + Ribavirin in Chronic Hepatitis C PatientsTerminatedPhase 1Institut National de la Santé Et de la Recherche Médicale, FranceNCT01567540Written as Sitagliptin
- A Pilot Study to Evaluate the Safety of a 3 Weeks Sitagliptin Treatment in HCC Patients Undergoing Liver ResectionCompletedPhase 1Institut National de la Santé Et de la Recherche Médicale, FranceNCT02650427Written as Sitagliptin
- Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes.CompletedPhase 4Fundación para la Investigación del Hospital Clínico de ValenciaNCT06851962Written as Sitagliptin
- Effect of Sitagliptin on Polycystic Ovarian Syndrome PatientsCompletedPhase 2/3Beni-Suef UniversityNCT05972928Written as Sitagliptin 100mg
- A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults.CompletedPhase 1AbbVieNCT07567781Written as Sitagliptin
- Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 50 mg/1000 mg in Healthy Subjects, Fed Study.CompletedNot applicableADIUMNCT07763912Written as Sitagliptin/Metformin FDC
- Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 50 mg/1000 mg in Healthy Subjects, Fast Study.CompletedNot applicableADIUMNCT07763899Written as Sitagliptin/Metformin FDC
- Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 100 mg/1000 mg in Healthy Subjects, Fed Study.CompletedNot applicableADIUMNCT07763964Written as Sitagliptin/Metformin FDC
See all 313 studies that test sitagliptin →
Given in every arm · 20 — sitagliptin is usual care beside what is tested
- Doxycycline in Type II DiabetesCompletedPhase 1/2Mostafa BahaaNCT06329882Written as Sitagliptin 100mg
- Mangosteen Supplement as Adjuvant Therapy With Sitagliptin/Metformin in Iraqi Patients With Type 2 DiabetesCompletedNot applicableMais Qais HbeebNCT07172269Written as Sitagliptin + Metformin
- Study to Evaluate the Efficacy and Safety of DA-1241 in Subjects With Presumed NASHCompletedPhase 2NeuroBo Pharmaceuticals Inc.NCT06054815Written as Sitagliptin
- A Pharmacokinetic Study of SID1903 (FDC of Dapagliflozin and Sitagliptin) in Healthy Adult VolunteersCompletedPhase 1SK Chemicals Co., Ltd.NCT05236998Written as Dapagliflozin and Sitagliptin
- Dipeptidyl Peptidase-4 Inhibition in Psoriasis Patients With Diabetes (DIP): A Randomized Clinical Trial.CompletedPhase 2University College DublinNCT01991197Written as Sitagliptin
- A Comparison of Two Treatment Strategies in Older Participants With Type 2 Diabetes Mellitus (T2DM)TerminatedPhase 4Eli Lilly and CompanyNCT02072096Written as Sitagliptin
- Study of Management of Pasireotide-induced Hyperglycemia in Adult Patients With Cushing's Disease or AcromegalyCompletedPhase 4Novartis PharmaceuticalsNCT02060383Written as Sitagliptin
- Ertugliflozin vs. Glimepiride in Type 2 Diabetes Mellitus (T2DM) Participants on Metformin (MK-8835-002)CompletedPhase 3Merck Sharp & Dohme LLCNCT01999218Written as Sitagliptin
- Safety and Efficacy of Ertugliflozin in the Treatment of Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin (MK-8835-006; VERTIS SITA2)CompletedPhase 3Merck Sharp & Dohme LLCNCT02036515Written as Sitagliptin
- Double-blind Ipragliflozin Add-on Study in Japanese Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Sitagliptin (MK-0431J-843)CompletedPhase 3Merck Sharp & Dohme LLCNCT02577003Written as Sitagliptin
- Effect of DPP4 Inhibition on VasoconstrictionCompletedPhase 4Vanderbilt UniversityNCT02639637Written as Sitagliptin
- A Study of LY3325656 in Healthy Participants and Participants With Type 2 DiabetesCompletedPhase 1Eli Lilly and CompanyNCT03115099Written as Sitagliptin
- Metformin Add-on Regimen Comparison Study in Japanese Participants With Type 2 Diabetes Mellitus (MK-0431A-136)CompletedPhase 3Merck Sharp & Dohme LLCNCT01545388Written as Sitagliptin
- A Study of the Safety and Efficacy of Glimepiride, Gliclazide, Repaglinide or Acarbose When Added to Sitagliptin + Metformin Combination Therapy in Chinese Participants With Diabetes (MK-0431-313)CompletedPhase 4Merck Sharp & Dohme LLCNCT01709305Written as Sitagliptin
- Effect of DPP4 Inhibition on Growth Hormone SecretionCompletedPhase 4Vanderbilt UniversityNCT01701973Written as Sitagliptin
- Effects of Exercise and Inhibition of Dipeptidyl Peptidase-4 on Insulin Secretion in Subjects With Type 1 DiabetesCompletedPhase 2University Hospital, Basel, SwitzerlandNCT02127047Written as Sitagliptin
- Addition Of Januvia (Sitagliptin) Improves Glycemic Control In Patients Inadequately Controlled By Metformin (MK0431-078)CompletedPhase 3Merck Sharp & Dohme LLCNCT00545584Written as sitagliptin phosphate
- Effect of Detemir and Sitagliptin on Blood Glucose Control in Type 2 DiabetesCompletedPhase 3Novo Nordisk A/SNCT00789191Written as sitagliptin
- Treatment of Wolfram Syndrome Type 2 With the Chelator Deferiprone and Incretin Based TherapyStatus unknownPhase 2/3Hadassah Medical OrganizationNCT02882477Written as Sitagliptin and Metformin
- Evaluation of the Effect of Dapagliflozin in Combination With Metformin on Body Weight in Subjects With Type 2 DiabetesCompletedPhase 3AstraZenecaNCT00855166Written as Sitagliptin
As the comparator · 87 — what is tested is compared with sitagliptin
- Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset DiabetesRecruitingPhase 3The University of Texas Health Science Center at San AntonioNCT06246799Written as Sitagliptin
- Triple Hypoglycemic Regimens In Patients With Newly Diagnosed Type 2 Diabetes MellitusRecruitingPhase 1/2Second Affiliated Hospital of Guangzhou Medical UniversityNCT07374328Written as Sitagliptin (DPP4 inhibitor)
- A Phase IV Clinical Trial to Compare the Efficacy and Safety of Metformin+Sodium-Glucose Cotransporter 2 Inhibitor(SGLT2-i)+Thiazolidinedione (TZD) in Patients With Type 2 DiabetesRecruitingPhase 4Boryung Pharmaceutical Co., LtdNCT06972732Written as Dapagliflozin/Sitagliptin
- Comparison Between Efficacy of Trelagliptin and Sitagliptin in Type II Diabetic PatientsEnrolling by invitationPhase 3Khyber Medical College, PeshawarNCT07073768Written as Sitagliptin 100mg OD
- To Compare the Safety and Efficacy of Dapagliflozin Plus Metformin Versus Sitagliptin Plus Metformin for Treatment of Diabetes in Patients With Compensated and Stable Decompensated CirrhosisNot yet recruitingNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT06147518Written as Sitagliptin
- Semaglutide vs SitagliptinActive, not recruitingPhase 4University Health Network, TorontoNCT05195944Written as Sitagliptin 100mg
- Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of MBX-2982 Administered Daily for 4 Weeks as Monotherapy in Patients With Type 2 DiabetesCompletedPhase 2Gilead SciencesNCT01035879Written as Sitagliptin
- Efficay and Safety of Empagliflozin Versus Sitagliptin for the In-patient Management of HyperglycemiaCompletedNot applicableMedanta, The Medicity, IndiaNCT06187285Written as Sitagliptin 100mg
- Exploratory Study to Compare the Effects of Tenelia® or Januvia® on Glucose Variability in add-on to Metformin (CGMS Study)CompletedPhase 4Handok Inc.NCT02512523Written as Sitagliptin
- Sitagliptin in Combination With Beidougen Capsule for Type 2 DiabetesStatus unknownPhase 4Beijing Chao Yang HospitalNCT05667220Written as Sitagliptin
- Cardiovascular Effects of GLP-1 Receptor ActivationCompletedPhase 4Vanderbilt University Medical CenterNCT03101930Written as Sitagliptin
- Efficacy of Ipragliflozin Compared With Sitagliptin in Uncontrolled Type 2 Diabetes With Sulfonylurea and MetforminCompletedPhase 3Seoul National University Bundang HospitalNCT03076112Written as Sitagliptin
- IDG-16177 for the Evaluation of Its Safety and PharmacokineticsStatus unknownPhase 1IlDong Pharmaceutical Co LtdNCT04982705Written as [Part 2] Sitagliptin
- Efficacy and Long-term Safety of Oral Semaglutide Versus Sitagliptin in Subjects With Type 2 DiabetesCompletedPhase 3Novo Nordisk A/SNCT02607865Written as sitagliptin
- Efficacy and Safety of Oral Semaglutide Using a Flexible Dose Adjustment Based on Clinical Evaluation Versus Sitagliptin in Subjects With Type 2 Diabetes Mellitus.CompletedPhase 3Novo Nordisk A/SNCT02849080Written as sitagliptin
- The Effect of Glimepiride Compared With Sitagliptin as an add-on Therapy to Metformin in Severe Insulin Deficiency DiabetesStatus unknownPhase 4Peking University People's HospitalNCT05386186Written as Sitagliptin
- Effect of CPL-2009-0031 in the Treatment of Patients With Uncontrolled Type 2 Diabetes MellitusCompletedPhase 3Cadila PharnmaceuticalsNCT04801199Written as Sitagliptin 100mg
- Metabolic Responses of Dapagliflozin vs Sitagliptin in T2DM Patients Inadequately Controlled With Insulin TherapyCompletedPhase 4The University of Hong KongNCT03959501Written as Sitagliptin 100mg
- Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin in Subjects With Type 2 Diabetes (SUSTAIN - CHINA MRCT)CompletedPhase 3Novo Nordisk A/SNCT03061214Written as Sitagliptin
- A Study to Evaluate the Safety, Tolerability, PK and PD of DA-1241 in Healthy Male Subjects and Subjects With T2DMCompletedPhase 1Dong-A ST Co., Ltd.NCT03646721Written as Sitagliptin
Showing 20 of 87.
Codes
What other systems call sitagliptin · ClinicalTrials.gg INT006560
- MeSH (NLM) D000068900Sitagliptin PhosphateConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) QFP0P1DV7ZSITAGLIPTINConfirmed FDA, NLM, Wikidata
- RxNorm 593411Confirmed FDA, Wikidata
- Wikidata Q419832sitagliptinConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C73838SitagliptinOne source FDA
- DrugBank DB01261One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000068900 | Sitagliptin Phosphate | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | QFP0P1DV7Z | SITAGLIPTIN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 593411 | — | Confirmed FDA, Wikidata |
| Wikidata | Q419832 | sitagliptin | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C73838 | Sitagliptin | One source FDA |
| DrugBank | DB01261 | — | One source Wikidata |
Also registered as sitagliptin phosphate (UNII TS63EW8X6F · RxNorm 621590) and sitagliptin phosphate anhydrous (UNII 494P4635I6).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.