Thiazide diuretics clinical trials
A class of medicines: the studies that test any of its 7 members, each study once. Members are as MeSH files each medicine’s actions, and as the NCI Thesaurus classes newer ones. In MeSH: Sodium Chloride Symporter Inhibitors.
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Medicines in this class
Studies that test each. A study of two counts under both, and once above.
- Bendroflumethiazide
- 2
- Capozide
- 1
Studies by the year they started
261 studies that test it; most in 2005 (22)
| Year | Studies |
|---|---|
| 1997 | 1 |
| 1998 | 2 |
| 1999 | 4 |
| 2000 | 4 |
| 2001 | 1 |
| 2002 | 3 |
| 2003 | 7 |
| 2004 | 14 |
| 2005 | 22 |
| 2006 | 19 |
| 2007 | 15 |
| 2008 | 14 |
| 2009 | 13 |
| 2010 | 12 |
| 2011 | 7 |
| 2012 | 6 |
| 2013 | 14 |
| 2014 | 18 |
| 2015 | 10 |
| 2016 | 10 |
| 2017 | 7 |
| 2018 | 5 |
| 2019 | 9 |
| 2020 | 2 |
| 2021 | 7 |
| 2022 | 8 |
| 2023 | 6 |
| 2024 | 10 |
| 2025 | 4 |
| 2026 | 7 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 117 · Other 147
Novartis (33) · Boehringer Ingelheim (17) · Daiichi Sankyo (6) · Sanofi (5) · Novartis Pharmaceuticals (5) · Boryung Pharmaceutical Co., Ltd (4) · Mylan Pharmaceuticals Inc (4) · Hospital de Clinicas de Porto Alegre (4)
Studies
Open first, then newest update. How each study uses a medicine is read from its arms, and is right about nine times in ten. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing one of them · 264
- Optimal Diuretic Therapies for Acute Heart Failure With Volume OverloadRecruitingPhase 3Johannes GrandNCT06166654Written as Metolazone 2.5 MG
- Cardiac Effects of Mineralocorticoid Receptor Antagonism After Hypertensive Disorders of PregnancyRecruitingPhase 2Massachusetts General HospitalNCT07238400Written as Chlorthalidone 25 mg daily
- Mechanisms of Diuretic Resistance in Heart Failure, Aim 2RecruitingPhase 1Yale UniversityNCT05753059Written as Bendroflumethiazide
- HYDROchlorothiazide to PROTECT Polycystic Kidney Disease Patients and Improve Their Quality of LifeRecruitingPhase 3University Medical Center GroningenNCT05373264Written as Hydrochlorothiazide 25 mg
- Evaluating the Use of Oral Indapamide to Reduce Disabiltiy Progression in Progressive Multiple Sclerosis (MS)Not yet recruitingPhase 2Eva M.M. StrijbisNCT07765212Written as Indapamide
- CaOx Stone PreventionRecruitingPhase 4Icahn School of Medicine at Mount SinaiNCT07225764Written as Chlorthalidone
- Comparative Effectiveness of Dual Antihypertensive Regimens in Patients After Percutaneous Coronary InterventionRecruitingNot applicableNational Medical Research Center for Therapy and Preventive MedicineNCT07683585Written as Losartan + Hydrochlorothiazide
- TACTIC-HF: Sequential Diuretic Strategies in Ambulatory Worsening Heart FailureNot yet recruitingPhase 4Lucrecia Maria BurgosNCT07593612Written as Hydrochlorothiazide (HCT)
- Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite AthletesEnrolling by invitationNot applicableEnhanced Emirates LimitedNCT07568574Written as Chlorothiazide
- Indapamide and Chlorthalidone to Reduce Urine Supersaturation for Kidney Stone PreventionRecruitingPhase 2Insel Gruppe AG, University Hospital BernNCT06111885Written as Indapamide 2.5 MG
- Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in HypertensionRecruitingPhase 4Brigham and Women's HospitalNCT05593055Written as Chlorthalidone
- POcus INTERvention for Tailoring Diuretic Strategy in Acute Decompensated Heart FailureNot yet recruitingPhase 2/3Hospital de Clinicas de Porto AlegreNCT07469722Written as Hydrochlorothiazide (HCTZ) 25 milligrams.
- Add-on Diuretics in Acute Decompensated Heart FailureRecruitingPhase 2Tanta UniversityNCT07372040Written as metolazone
- Blood Pressure Control With Thiazide Diuretics in Peritoneal Dialysis PatientsRecruitingPhase 4Chinese University of Hong KongNCT07271420Written as Hydrochlorothiazide 25mg once per day
- Ertugliflozin in Chronic Heart FailureRecruitingPhase 2Yale UniversityNCT04438213Written as Metolazone
- Treatment With Indapamide in Patients With Post-Surgical HypoparathyroidismRecruitingPhase 4Lars RejnmarkNCT07034677Written as Indapamide 1.5 MG SR
- The Role of Skin Sodium Accumulation in Chronic Kidney DiseaseRecruitingNot applicableAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)NCT07020104Written as Hydrochlorothiazide
- Mitigating the Pro-inflammatory Phenotype of ObesityRecruitingPhase 1University of Kansas Medical CenterNCT04934228Written as Hydrochlorothiazide 12.5Mg Tab
- Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume OverloadRecruitingPhase 4Cairo UniversityNCT06414759Written as Metolazone
- Comparison of the Role of Losartan Alone vs Hydrochlorothiazide Plus LosartanNot yet recruitingNot applicableRESnTEC, Institute of ResearchNCT06491940Written as Losartan + Hydrochlorothiazide
See all 264 studies that test one of the thiazide diuretics →
Codes
What other systems call Thiazide diuretics · ClinicalTrials.gg INT008862
- MeSH (NLM) D049993Sodium Chloride Symporter InhibitorsOne source ClinicalTrials.gov
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D049993 | Sodium Chloride Symporter Inhibitors | One source ClinicalTrials.gov |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.