Proteinuria clinical trials
The registry lists 328 studies for Proteinuria across more than 10 countries. 44 are recruiting or about to start. 71 of them are mainly about Proteinuria (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 2 narrower conditions too, such as Albuminuria: 460 studies, 66 open.
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Who runs them
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (15) · Novartis Pharmaceuticals (10) · Gulhane School of Medicine (5) · Medical University of Gdansk (5) · Mario Negri Institute for Pharmacological Research (5) · Odense University Hospital (4) · AstraZeneca (4) · Children's Hospital of Fudan University (4)
What is being tested here
Drugs under test in Proteinuria studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Iptacopan | 3 | 4 | 4 |
| Huaier Extract Granule | 2 | 0 | 3 |
| Empagliflozin | 2 | 2 | 3 |
| JADE101 | 2 | 1 | 2 |
| Losartan | 1 | 5 | 15 |
| Dapagliflozin | 1 | 1 | 6 |
| Rituximab | 1 | 2 | 6 |
| Mycophenolic Acid | 1 | 2 | 5 |
| Cyclosporine | 1 | 0 | 4 |
| Amiloride | 1 | 0 | 4 |
Drug classes tested here Angiotensin receptor blockers (ARBs) 2 open · SGLT2 inhibitors 2 open · Diuretics 2 open · Endothelin receptor antagonists 2 open · Mineralocorticoid receptor antagonists (MRAs) 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026The Efficacy and Safety of Dapagliflozin in the Treatment of Hereditary Kidney Disease With Proteinuria in Children · Phase 3 · Children's Hospital of Fudan University
- Jan 2027Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy. · Phase 3 · Novartis Pharmaceuticals
- Apr 2027A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria · Phase 3 · Bayer
- Oct 2027FINEPKT - Finerenone in Proteinuria Patients After Kidney Transplan · Phase 3 · kewen Chen,MD
- Nov 2026Kidney Health: Eat Well, Live Well · University of Texas at Austin
- Nov 2026Proteinuria in Pre and Post Transplant · University of Miami
- Dec 2026Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE) · Wake Forest University Health Sciences
- Dec 2026Sparsentan for the Treatment of VEGF Signaling Pathway Inhibitor-Associated Proteinuria · Brigham and Women's Hospital
- Dec 2026Nefecon and Ambrisentan in IgA Nephropathy · The First Hospital of Jilin University
- Jan 2027A Smart Phone Application to Improve Adoption of the 2024 Kidney Disease Improving Global Outcomes (KDIGO) Chronic Kidney Disease (CKD) Guidelines · St. James's Hospital, Ireland
Who these studies take
Of the 31 Proteinuria studies recruiting now, 11 (35%) set no upper age limit and 16 (52%) stop at 75 or younger. 12 (39%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (10%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 8 (26%) | 8 (26%) |
| 18 | 29 (94%) | 29 (94%) |
| 30 | 23 (74%) | 23 (74%) |
| 40 | 22 (71%) | 22 (71%) |
| 50 | 22 (71%) | 22 (71%) |
| 65 | 19 (61%) | 19 (61%) |
| 75 | 16 (52%) | 16 (52%) |
| 85 | 15 (48%) | 15 (48%) |
Across all 328 studies, recruiting or not: 47% stop at 75 or younger and 27% at 65; 20% take children; 6% are for women only and 1% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Proteinuria studies take
Of 25 phase 2 interventional studies under Proteinuria, half reached primary completion within 29 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 29 mo17–52 · 25 studies | — | — |
| Phase 3 | 64 mo21–78 · 20 studies | — | — |
| Observational | 62 mo20–… · 22 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Started recruiting1
- A Phase 3 Blinded Study of JADE101 in Participants With Immunoglobulin A NephropathyNov 3, 2026NCT07902817
Results posted1
- Study of Efficacy and Safety of LNP023 in Primary IgA Nephropathy PatientsNov 4, 2026NCT04578834
Stopped1
- Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- VTerminatedOct 15, 2026NCT05268289
Newly registered1
- A Phase 3 Blinded Study of JADE101 in Participants With Immunoglobulin A NephropathyOct 29, 2026NCT07902817
Studies
Recruiting first, then most recently updated. Showing 50 of 328. Browse all 328 → or search them.
- A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS)RecruitingNCT07268638Phase 21 country
- Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.RecruitingNCT04817618Phase 319 countries
- Hypertension in Children and Young People at Risk of Autosomal Dominant Polycystic Kidney DiseaseRecruitingNCT072600711 country
- A Phase 3 Blinded Study of JADE101 in Participants With Immunoglobulin A NephropathyRecruitingNCT07902817Phase 31 country
- A Study of JADE101 in Participants With Immunoglobulin A NephropathyRecruitingNCT07541287Phase 25 countries
- An Open-Label Phase 2 Study of N-Acetyl-D-Mannosamine (ManNAc) in Subjects With Podocyte DiseasesRecruitingNCT06664814Phase 21 country
- Urinary Vitamin C Loss in Diabetic SubjectsRecruitingNCT000715261 country
- Rituximab Plus Cyclosporine in Idiopathic Membranous NephropathyRecruitingNCT00977977Phase 21 country
- A Study to Assess the Effects of Zigakibart on IgA Nephropathy.RecruitingNCT07146906Phase 211 countries
- Clinical Phenotyping Resource and Biobank Core of the Michigan O'Brien Renal CenterEnrolling by invitationNCT010166131 country
- Therapeutic Effect of Hydroxychloroquine on Immunoglobulin A (IgA) Nephropathy Course QUIgAN StudyRecruitingNCT06350630Phase 21 country
- A Study of the Efficacy and Safety of Zigakibart + Atrasentan in Adult Patients With Primary IgA NephropathyNot yet recruitingNCT07850752Phase 3
- A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and ProteinuriaRecruitingNCT05457283Phase 332 countries
- Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Iptacopan in Pediatric Patients With Primary IgANRecruitingNCT06994845Phase 38 countries
- Efficacy and Safety of Mycophenolate Mofetil in Refractory IgA NephropathyNot yet recruitingNCT07785128Phase 21 country
- Sparsentan for the Treatment of VEGF Signaling Pathway Inhibitor-Associated ProteinuriaRecruitingNCT07224776Phase 11 country
- Study of Ravulizumab in Pediatric Participants With Primary IgANRecruitingNCT07024563Phase 37 countries
- Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGNRecruitingNCT05755386Phase 323 countries
- The Efficacy and Safety of Dapagliflozin in the Treatment of Hereditary Kidney Disease With Proteinuria in ChildrenRecruitingNCT06890143Phase 31 country
- Improving Renal Complications in Adolescents With Type 2 Diabetes Through REsearch Cohort Study (National iCARE Study)RecruitingNCT028181921 country
- A Study of Iptacopan in Korean Patients With Paroxysmal Nocturnal Hemoglobinuria or C3 GlomerulopathyRecruitingNCT074161621 country
- Study of BHV-1400 in IgA NephropathyRecruitingNCT07054684Phase 12 countries
- A Study to Determine if BHV-1400 is Effective and Safe in Adults With IgA NephropathyNot yet recruitingNCT07642050Phase 3
- SGLT2 Inhibitors in Adult Primary Nephrotic SyndromeRecruitingNCT07214818Phase 2/31 country
- Optimizing Referral Pathways for Patients With Hematuria and Moderate-Severe ProteinuriaNot yet recruitingNCT07431931Not applicable1 country
- A Smart Phone Application to Improve Adoption of the 2024 Kidney Disease Improving Global Outcomes (KDIGO) Chronic Kidney Disease (CKD) GuidelinesRecruitingNCT07561957Not applicable1 country
- Empagliflozin Treatment in Kidney Transplant RecipientsRecruitingNCT06013865Phase 41 country
- A Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of Treatment With AP1189 in Patients With iMN and Severe ProteinuriaRecruitingNCT04456816Phase 21 country
- Clinical Study on the Use of Huaier Granules for the Treatment of Proteinuria Related to Bevacizumab and Anlotinib in Lung Cancer PatientsNot yet recruitingNCT07358520Phase 41 country
- Huaier Granule and ProteinuriaNot yet recruitingNCT07355361Phase 21 country
- CHART-C3G/CLNP023B12011Not yet recruitingNCT07331259
- Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)RecruitingNCT047522931 country
- Proteinuria in Pre and Post TransplantRecruitingNCT010943271 country
- Nefecon and Ambrisentan in IgA NephropathyRecruitingNCT07030894Phase 41 country
- Role of Vitamin K2 in Chronic Kidney DiseaseRecruitingNCT05942053Phase 41 country
- Role of Coenzyme Q10 in Chronic Kidney DiseaseRecruitingNCT05942027Phase 41 country
- Beneficial Effect of Amiloride on Progression of Chronic Kidney DiseaseRecruitingNCT06923709Phase 21 country
- Biomarkers and Outcome Predictors of Pediatric Nephrotic Syndrome: A Genetic, Transcriptomic, and Secretome Multiomics StudyNot yet recruitingNCT06792448
- Effect Camostat for Kidney Protection in Chronic Kidney DiseaseRecruitingNCT06794593Phase 21 country
- Efficacy of On-venous Laser Irradiation of Blood on Diabetes Kidney Disease PatientsEnrolling by invitationNCT06588465Not applicable1 country
- Comparison of the Role of Losartan Alone vs Hydrochlorothiazide Plus LosartanNot yet recruitingNCT06491940Not applicable1 country
- EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIVEnrolling by invitationNCT0269973636 countries
- ARREST-NEPHROSIS - Austrian Resistant Nephrotic Syndrome Treatment Response Registry and BiobankRecruitingNCT061625461 country
- Effect of Dapagliflozin in Non-Diabetic Patients With Nephrotic Syndrome.Not yet recruitingNCT05966818Phase 4
- Study of Efficacy and Safety of LNP023 in Primary IgA Nephropathy PatientsCompletedNCT04578834Phase 335 countries
- Serum and Urinary sCD163 in IgA NephropathyCompletedNCT077540191 country
- Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- VTerminatedNCT05268289Phase 219 countries
- A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and ProteinuriaActive, not recruitingNCT05196035Phase 332 countries
- Body Composition, Urine Protein, and Kidney Blood Flow After Nutritional Counseling in Children With Nutcracker SyndromeCompletedNCT078684061 country
- Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)Active, not recruitingNCT06291376Phase 328 countries