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Prehypertension clinical trials

The registry lists 158 studies for Prehypertension across more than 10 countries. 21 are recruiting or about to start. 87 of them are mainly about Prehypertension (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.

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Status

Completed
96
Status unknown
21
Recruiting
11
Terminated
10
Not yet recruiting
9
Withdrawn
6

Phase

Phase 2
17
Phase 4
14
Phase 3
11
Phase 1
6

Where

United States
82
China
8
Korea, Republic of
7
Brazil
7
United Kingdom
5
Pakistan
5

Who runs them

University of Alabama at Birmingham (6) · University of California, San Diego (5) · Florida State University (5) · Johns Hopkins University (4) · Riphah International University (3) · Brown University (3) · University of Minnesota (2) · Capital Medical University (2)

What is being tested here

Drugs under test in Prehypertension studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Amlodipine103
Allisartan isoproxil102
Empagliflozin101
Nigella sativa101
Orforglipron111
Metoprolol003
Nebivolol003
Allopurinol012
Hydrochlorothiazide002
Amiloride012

Drug classes tested here Angiotensin receptor blockers (ARBs) 1 open · Beta blockers 5 · Diuretics 4 · Thiazide diuretics 3

Coming up

1phase 3 study under way
8studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 8

Who these studies take

Of the 11 Prehypertension studies recruiting now, 3 (27%) set no upper age limit and 7 (64%) stop at 75 or younger. 3 (27%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 6 (55%) take healthy volunteers.

Recruiting studies that take each age, of 11
AgeWomenMen
102 (18%)2 (18%)
187 (64%)7 (64%)
308 (73%)8 (73%)
408 (73%)8 (73%)
509 (82%)9 (82%)
656 (55%)6 (55%)
754 (36%)4 (36%)
853 (27%)3 (27%)

Across all 158 studies, recruiting or not: 67% stop at 75 or younger and 49% at 65; 8% take children; 7% are for women only and 4% for men only; 53% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Prehypertension studies take

Of 60 interventional studies with no phase under Prehypertension, half reached primary completion within 20 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase20 mo11–37 · 60 studies—20 mo13–37 · 56 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 50 of 158. Browse all 158 → or search them.