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Rituximab clinical trials

Also written Rituxan, Mabthera, IDEC-C2B8 and MK-8808.

Includes 7 studies of Rituximab and Hyaluronidase Human.

studies test it
1,283
open now
158
in phase 3
253
first study started
1993
Related medicines add 3 studies

Counted the way a researcher would: Rituximab with its salts, dosage forms, brands and biosimilars. Looking for a trial to join? Including related medicines shows more you could take part in.

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How each study uses Rituximab is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study

Get an email when these change. Save the Rituximab studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

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Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

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Approvals

The first approval found in each region, with its record

United States
26 Nov 1997 · RITUXAN · BLA 103705 (FDA, Drugs@FDA)
European Union
2 Jun 1998 · MabThera · EMEA/H/C/000165 (EMA)

From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out

How studies write it

Studies that test it under each name

Name

Rituximab
1,008
MOAB IDEC-C2B8
44
IDEC-C2B8 monoclonal antibody
40
rituximab [MabThera/Rituxan]
22
MabThera/Rituxan
14

Brand

Rituxan
339
Mabthera
173

Development codes

IDEC-C2B8
51
MK-8808
2
RO0452294
1

In one entry with another drug

Given together, or one or the other

dexamethasone and rituximab
2
Bendamustine, Rituximab
2
Rituximab and Bendamustine
2
bortezomib + rituximab
2
IVIG and Rituximab
2
Recombinant Human Interleukin-2 and Rituximab
2

Biosimilars

Rixathon
7
Ruxience
2
ABP 798
2

Studies by the year they started

1,270 studies that test it; most in 2006 (82); 2 more planned to start later

Studies that test Rituximab, by start year
YearStudies
19931
19952
19976
199816
199918
200019
200121
200232
200354
200471
200576
200682
200765
200859
200970
201054
201152
201253
201341
201438
201544
201642
201726
201833
201948
202045
202131
202225
202349
202433
202534
202630

Who runs them

Industry 201 · Other 1,082

M.D. Anderson Cancer Center (73) · Hoffmann-La Roche (60) · National Cancer Institute (NCI) (59) · Memorial Sloan Kettering Cancer Center (26) · Mayo Clinic (23) · Assistance Publique - Hôpitaux de Paris (22) · Alliance for Clinical Trials in Oncology (17) · Genentech, Inc. (17)

Often tested with

Tested in the same studies.

Cyclophosphamide (162) · Lenalidomide (95) · Fludarabine (88) · Bendamustine (72) · Prednisone (64) · Vincristine (63) · Bortezomib (60) · Doxorubicin (59)

Related medicines

As reviewed, each with the page that says it.

Coming up

From the study records. Dates are the sponsors’ own estimates and often move.

Tested against it · 35 phase 3 studies under way

Rituximab is the comparator. A study of two new drugs counts under both.

  • 3Mosunetuzumab · The Lymphoma Academic Research Organisation, Hoffmann-La Roche · next primary completion Sep 2027
  • 3Acalabrutinib · Acerta Pharma BV, AstraZeneca · next primary completion Aug 2027
  • 3Lenalidomide · The Lymphoma Academic Research Organisation, Beijing InnoCare Pharma Tech Co., Ltd. · next primary completion Sep 2027
  • 3Odronextamab · Regeneron Pharmaceuticals · next primary completion Feb 2028
  • 2Pirtobrutinib · Loxo Oncology, Inc.
  • 2Axicabtagene ciloleucel · Kite, A Gilead Company · next primary completion Oct 2030
  • 2ARQ531 · Merck Sharp & Dohme LLC · next primary completion May 2027
  • 2SCTB35 · Sinocelltech Ltd. · next primary completion Nov 2027
Reaching primary completion within a year · 62, 11 in phase 3

Studies that test Rituximab, phase 3 first.

Studies

Open first, then newest update. How each study uses Rituximab is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.

Testing it · 1,283

See all 1,283 studies that test Rituximab →

Given beside what is tested · 589 — Rituximab is usual care or a partner of the new treatment

Showing 20 of 589.

As the comparator · 102 — what is tested is compared with Rituximab

Showing 20 of 102.

Codes

What other systems call Rituximab · ClinicalTrials.gg INT006567

  • MeSH (NLM) D000069283RituximabConfirmed ClinicalTrials.gov, NLM, Wikidata
  • UNII (FDA) 4F4X42SYQ6RITUXIMABConfirmed FDA, NLM, Wikidata
  • RxNorm 121191Confirmed FDA, Wikidata
  • Wikidata Q412323rituximabConfirmed FDA, NLM, Wikidata
  • NCI Thesaurus C1702RituximabOne source FDA
  • DrugBank DB00073One source Wikidata

“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.