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Lymphoma, Large B-Cell, Diffuse clinical trials

The registry lists 1,868 studies for Lymphoma, Large B-Cell, Diffuse across more than 10 countries. 355 are recruiting or about to start. 943 of them are mainly about Lymphoma, Large B-Cell, Diffuse (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

ClinicalTrials.gov finds 2,169 studies for Lymphoma, Large B-Cell, Diffuse. How that becomes 1,868 here

This page counts the studies the registry files under Lymphoma, Large B-Cell, Diffuse, and those it files under no condition that list Lymphoma, Large B-Cell, Diffusethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 2,169Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −101List Lymphoma, Large B-Cell, Diffuse as a condition, but the registry did not file them under itMost often written as “DLBCL - Diffuse Large B Cell Lymphoma” (42), “Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma” (10), and “Diffuse Large B Cell Lymphoma Refractory” (5). The registry filed them under other conditions only, most often Dendritic Cell Sarcoma, Interdigitating (52) and Lymphoma (25).
  3. −200Match it another way121 name it in the title, 28 in a keyword, and 51 by a synonym or other text the search reads.
  4. 1,868The count on this page39 of them list Lymphoma, Large B-Cell, Diffuse in their own words; the registry filed them under no condition.

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Status

Completed
873
Recruiting
265
Terminated
256
Status unknown
170
Active, not recruiting
132
Not yet recruiting
80

Phase

Phase 2
899
Phase 1
684
Phase 3
187
Early Phase 1
21
Phase 4
13

Where

United States
1,130
China
304
France
182
Italy
166
United Kingdom
130
Spain
128

Who runs them

National Cancer Institute (NCI) (128) · Fred Hutchinson Cancer Center (67) · Memorial Sloan Kettering Cancer Center (40) · City of Hope Medical Center (39) · Ruijin Hospital (36) · M.D. Anderson Cancer Center (31) · Case Comprehensive Cancer Center (27) · Novartis Pharmaceuticals (26)

What is being tested here

Drugs under test in Lymphoma, Large B-Cell, Diffuse studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Rituximab2032212
Zanubrutinib16127
Polatuzumab vedotin15528
Epcoritamab15323
Lenalidomide14865
Glofitamab13119
Cyclophosphamide118109
Tucidinostat10319
Orelabrutinib8210
Gemcitabine6434

Drug classes tested here Tyrosine kinase inhibitors (TKIs) 41 open · Antimetabolites 21 open · Antibody-drug conjugates (ADCs) 19 open · Alkylating agents 18 open · HDAC inhibitors 14 open

Coming up

51phase 3 studies under way
132studies finish main data collection within a year9 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 265 Lymphoma, Large B-Cell, Diffuse studies recruiting now, 177 (67%) set no upper age limit and 50 (19%) stop at 75 or younger. 25 (9%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 7 (3%) take healthy volunteers.

Recruiting studies that take each age, of 265
AgeWomenMen
1015 (6%)15 (6%)
18236 (89%)236 (89%)
30238 (90%)238 (90%)
40236 (89%)236 (89%)
50235 (89%)235 (89%)
65247 (93%)247 (93%)
75244 (92%)244 (92%)
85196 (74%)196 (74%)

Across all 1,868 studies, recruiting or not: 24% stop at 75 or younger and 11% at 65; 17% take children; <1% are for women only and <1% for men only; 2% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Lymphoma, Large B-Cell, Diffuse studies take

Of 264 phase 2 interventional studies under Lymphoma, Large B-Cell, Diffuse, half reached primary completion within 52 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 155 mo36–82 · 196 studies49 mo33–71 · 84 studies57 mo39–86 · 112 studies
Phase 1/270 mo50–98 · 108 studies75 mo54–99 · 51 studies66 mo46–94 · 57 studies
Phase 252 mo35–85 · 264 studies37 mo22–57 · 54 studies57 mo40–96 · 210 studies
Phase 357 mo39–99 · 73 studies53 mo36–82 · 37 studies—
Interventional, no phase73 mo42–137 · 41 studies—73 mo42–144 · 40 studies
Observational52 mo29–114 · 66 studies—40 mo26–114 · 52 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 12, 2026.

Started recruiting5

Results posted8

Show 3 more

Stopped1

Newly registered11

Show 6 more

Studies

Recruiting first, then most recently updated. Showing 50 of 1,868. Browse all 1,868 → or search them.