Purpura, Thrombocytopenic, Idiopathic clinical trials
The registry lists 504 studies for Purpura, Thrombocytopenic, Idiopathic across more than 10 countries. 159 are recruiting or about to start. 474 of them are mainly about Purpura, Thrombocytopenic, Idiopathic (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
ClinicalTrials.gov finds 559 studies for Purpura, Thrombocytopenic, Idiopathic. How that becomes 502 here
This page counts the studies the registry files under Purpura, Thrombocytopenic, Idiopathic, and those it files under no condition that list Purpura, Thrombocytopenic, Idiopathicthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 559Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −7List Purpura, Thrombocytopenic, Idiopathic as a condition, but the registry did not file them under itMost often written as “Chronic Immune Thrombocytopenia” (2), “Auto-immune Thrombocytopenic Purpura” (1), and “Lymphoma Idiopathic Thrombocytopenic Purpura” (1). The registry filed them under other conditions only, most often Anemia, Hemolytic, Autoimmune (4) and Purpura (2).
- −50Match it another way35 name it in the title, 2 in a keyword, and 13 by a synonym or other text the search reads.
- 502The count on this page20 of them list Purpura, Thrombocytopenic, Idiopathic in their own words; the registry filed them under no condition.
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Who runs them
Peking University People's Hospital (48) · Shandong University (38) · Institute of Hematology & Blood Diseases Hospital, China (33) · Amgen (18) · Novartis Pharmaceuticals (17) · Assiut University (15) · University Hospital, Bordeaux (12) · GlaxoSmithKline (11)
Who develops what
Save this setEvery programme with a company-led study here in the last two years, whatever its size: 36 programmes from 33 companies, 30 with this as their studies’ main aim; 9 with a live phase 3 study; 12 primary completions in the next 12 months.
Comparator & background therapies
What other companies’ phase 2+ studies give as the comparator or the background here (its leading trial sponsor and partners left out): a sign of what new drugs are measured against, not by itself the standard of care, its prescriptions or its market.
| Drug | Leading trial sponsor · rights | Companies, last 5 years |
|---|---|---|
eltrombopagRecent, limitedEvidence
| GlaxoSmithKline59% of its industry studiesUS: off-patent, 11 generics marketedEU: off-patent, 2 generics authorised | 11 study |
Adrenal Cortex HormonesRecent, limitedEvidence
| — | 11 study |
PrednisoneRecent, limitedPhase 4 trial recordedEvidence
| Johnson & Johnson11% of its industry studies | 11 study |
3 more in limited or earlier use — sign in to see them, free.
Programmes
“Meets, by arms” reads each study’s arms: vs its arm against the therapy’s; + X vs a combination against it; added to it plus the therapy against the therapy; studied with given together only. The next primary completion is the next phase-3 study’s when there is one.
| In phase 3 | Company |
|---|---|
| rilzabrutinibApproved: US 2025 · EU 20252 live phase-3 studies: NCT07007962, NCT07216079 | Sanofi |
| Immunoglobulins, IntravenousApproved: EU 20061 live phase-3 study: NCT07059000 | kedrion s p a |
| Human immunoglobulin (pH4) for intravenous injection1 live phase-3 study: NCT07233213 | Grand Shuyang Life Sciences (Chengdu) Co., Ltd. |
| TQB34731 live phase-3 study: NCT06900920 | Sino Biopharmaceutical Limited |
| efgartigimod alfaApproved: US 2021 · EU 20223 live phase-3 studies: NCT04812925, NCT07194850, NCT06544499 | argenx |
The 5 in phase 3 with the nearest primary completion, of 36 programmes — sign in to see the whole list, free: filter by phase and aim, sort by late development, direct comparisons or the next primary completion.
Primary completion in the next 12 months (12)
Live phase 2 and 3 studies of these programmes. Primary completion is when the main measure’s data collection ends, as the registry states it (most are estimates); results come later, if they are announced.
- 25 Nov 2026 est.rilzabrutinib · Sanofi · Phase 3 main aimNCT07216079 Rilzabrutinib for the Adult Participants With Chronic ITP Who Have Completed Phase 3 Study in Japan — primary endpoint: AEs including SAEs and AESIs · 3 enrolled
- Dec 2026 est.Immunoglobulins, Intravenous · kedrion s p a · Phase 3 main aimNCT07059000 A Study Investigating Intravenous Human Normal Immunoglobulin 10% in Adults With Chronic Immune Thrombocytopenia (ITP) — primary endpoint: Rate of subjects with response (R) · 40 enrolled
- Dec 2026 est.Human immunoglobulin (pH4) for intravenous injection · Grand Shuyang Life Sciences (Chengdu) Co., Ltd. · Phase 3 main aimNCT07233213 An Open-label Study of Intravenous Immunoglobulin (5%) for the Treatment of Primary Immune Thrombocytopenia — primary endpoint: Improved platelet response within 7 days of the first transfusion · 36 enrolled
9 more — sign in to see them all, free.
Read from ClinicalTrials.gov, industry-led studies. Main aim: this is the study’s judged main condition; named, not the main aim: the sponsor names it, the study is about something else; registry mapping only: only the registry’s mapping put it here. Leading trial sponsor is the company leading the most industry studies of a drug, a measure of trial activity, not of rights. US and EU rights, and Approved: from the regulators’ records (FDA’s Drugs@FDA via openFDA; EMA’s medicines data) — the holder of a marketed or authorised original, generics and other companies’ versions; not rights elsewhere, nor approval for this condition. Phase 4 trial recorded, where neither lists it: a phase 4 study exists somewhere. Not read yet: labels by indication, exclusivity, licences, line of therapy, academic comparators, sales.
What is being tested here
Drugs under test in Purpura, Thrombocytopenic, Idiopathic studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Eltrombopag | 7 | 9 | 35 |
| Avatrombopag | 5 | 7 | 16 |
| Daratumumab | 5 | 0 | 6 |
| Romiplostim | 4 | 13 | 28 |
| Rituximab | 4 | 10 | 26 |
| Zanubrutinib | 4 | 0 | 5 |
| Teriflunomide | 3 | 0 | 4 |
| Immunoglobulins, Intravenous | 2 | 9 | 12 |
| Immunoglobulin G | 2 | 9 | 12 |
| Efgartigimod alfa | 2 | 7 | 8 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 13 open · JAK inhibitors 4 open · Corticosteroids 3 open · Proteasome inhibitors 1 open · Calcineurin inhibitors 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Efficacy and Safety of Subcutaneous Belimumab or Placebo in Addition of Rituximab in Persistent or Chronic Immune Thrombocytopenia · Phase 3 · Assistance Publique - Hôpitaux de Paris
- Nov 2026Rilzabrutinib for the Adult Participants With Chronic ITP Who Have Completed Phase 3 Study in Japan · Phase 3 · Sanofi
- Dec 2026A Study Investigating Intravenous Human Normal Immunoglobulin 10% in Adults With Chronic Immune Thrombocytopenia (ITP) · Phase 3 · Kedrion S.p.A.
- Dec 2026An Open-label Study of Intravenous Immunoglobulin (5%) for the Treatment of Primary Immune Thrombocytopenia · Phase 3 · Grand Shuyang Life Sciences (Chengdu) Co., Ltd.
- Mar 2027A Study of TQB3473 Tablets Compared to Placebo in the Treatment of Adult Primary Immune Thrombocytopenia · Phase 3 · Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
- Apr 2027High-Dose Dexamethasone Combined With Orelabrutinib Versus High-Dose Dexamethasone Combined With Placebo in Adult Patients With Newly Diagnosed Primary Immune Thrombocytopenia · Phase 3 · Shandong University
- Sep 2027Sirolimus in Patients With Systemic Lupus Erythematosus-Associated Immune Thrombocytopenia · Phase 3 · Chinese SLE Treatment And Research Group
- Oct 2027A Phase 3 Study to Evaluate the Safety and Efficacy of Efgartigimod PH20 Subcutaneous in Adult Patients With Primary Immune Thrombocytopenia · Phase 3 · argenx
- Nov 2027Study to Evaluate the Efficacy and Safety of Oral Rilzabrutinib in Adults With Immune Thrombocytopenia (ITP) Who Failed First-line Treatment · Phase 3 · Sanofi
- Nov 2026Biologic Characterization of Patients With ITP · Gruppo Italiano Malattie EMatologiche dell'Adulto
Who these studies take
Of the 103 Purpura, Thrombocytopenic, Idiopathic studies recruiting now, 49 (48%) set no upper age limit and 42 (41%) stop at 75 or younger. 27 (26%) take children under 18. 1 (1%) are for women only and 0 (0%) for men only; 4 (4%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 19 (18%) | 19 (18%) |
| 18 | 93 (90%) | 92 (89%) |
| 30 | 89 (86%) | 88 (85%) |
| 40 | 89 (86%) | 88 (85%) |
| 50 | 89 (86%) | 88 (85%) |
| 65 | 84 (82%) | 84 (82%) |
| 75 | 72 (70%) | 72 (70%) |
| 85 | 54 (52%) | 54 (52%) |
Across all 504 studies, recruiting or not: 41% stop at 75 or younger and 24% at 65; 25% take children; 2% are for women only and <1% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Purpura, Thrombocytopenic, Idiopathic studies take
Of 66 phase 2 interventional studies under Purpura, Thrombocytopenic, Idiopathic, half reached primary completion within 34 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 34 mo17–41 · 66 studies | — | — |
| Phase 3 | 28 mo22–49 · 57 studies | 25 mo21–44 · 41 studies | — |
| Observational | 55 mo35–… · 31 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 16, 2026.
Started recruiting1
- TGD001 Treatment in Thrombotic MicroangiopathiesNov 12, 2026NCT07459114
Stopped1
- Safety and Efficacy Study of PF-06835375 in Primary Immune ThrombocytopeniaTerminatedOct 16, 2026NCT05070845
Newly registered2
- An Open-label Phase I/II Safety and Feasibility Basket Study of UKT-CART19.1Nov 12, 2026NCT07932262
- Study of Thyroid Dysfunction in Immune Thrombocytopenic Purpura PatientsOct 28, 2026NCT07900334
Studies
Recruiting first, then most recently updated. Showing 50 of 504. Browse all 504 → or search them.
- TGD001 Treatment in Thrombotic MicroangiopathiesRecruitingNCT07459114Phase 1/21 country
- Study to Evaluate the Efficacy and Safety of Oral Rilzabrutinib in Adults With Immune Thrombocytopenia (ITP) Who Failed First-line TreatmentRecruitingNCT07007962Phase 310 countries
- Optimal Dose of Zanubrutinib to Treat Adult Immune ThrombocytopeniaNot yet recruitingNCT07315373Phase 2
- An Open-label Phase I/II Safety and Feasibility Basket Study of UKT-CART19.1Not yet recruitingNCT07932262Phase 1/21 country
- An Exploratory Study of CD19/CD22/BCMA CAR-T Cells (BZE2204) in Subjects With Relapsed or Refractory Autoimmune DiseasesRecruitingNCT07174843Early Phase 11 country
- A Study to Assess the Tolerability of Ianalumab (VAY736) With Investigator's Choice Thrombopoietin Receptor Agonist (IC TPO-RA) in Patients With Primary Immune Thrombocytopenia (ITP)RecruitingNCT07421167Phase 21 country
- A Study of Mezagitamab in Adults With Chronic Primary Immune ThrombocytopeniaRecruitingNCT06722235Phase 318 countries
- A Study of Pirtobrutinib in Participants With Immune ThrombocytopeniaRecruitingNCT06721013Phase 1/210 countries
- Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell DisordersRecruitingNCT07104565Phase 27 countries
- A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune ThrombocytopeniaRecruitingNCT06948318Phase 315 countries
- Phase 1 Dose Escalation Study of RXIM002 in Autoimmune CytopeniasNot yet recruitingNCT07765966Phase 1
- Study of Thyroid Dysfunction in Immune Thrombocytopenic Purpura PatientsNot yet recruitingNCT079003341 country
- A Study Investigating Intravenous Human Normal Immunoglobulin 10% in Adults With Chronic Immune Thrombocytopenia (ITP)RecruitingNCT07059000Phase 38 countries
- Safety and Preliminary Efficacy of CTX112 in Adult Participants With Relapsed/Refractory Hematologic Autoimmune DiseaseRecruitingNCT07549698Phase 1/23 countries
- A Study of Efgartigimod IV in Participants From 12 Years to Less Than 18 Years of Age With Chronic Immune Thrombocytopenia (ITP)RecruitingNCT07194850Phase 2/310 countries
- A Real-world Study of Treatment Patterns and Outcomes in Primary Immune Thrombocytopenia Patients Treated With EltrombopagRecruitingNCT075877231 country
- Cognitive Dysfunction in Chronic and Persistent Immune ThrombocytopeniaRecruitingNCT068173951 country
- A Study of Patients' Preferences for Primary Immune Thrombocytopenia TreatmentRecruitingNCT077860771 country
- Comparative Autoantibody and Immunologic Cell Marker StudyEnrolling by invitationNCT024228751 country
- A Study of Romiplostim Plus Predniso(lo)ne vs. Predniso(lo)ne Alone for the Treatment of Previously Untreated Primary Immune Thrombocytopenia (ITP)RecruitingNCT07700238Phase 31 country
- Safety, Tolerability, and Efficacy of NVG-2089 in Participants With Immune ThrombocytopeniaRecruitingNCT07095127Phase 21 country
- Clinical Study of CHT105 Injection in the Treatment of Relapsed/Refractory Autoimmune DiseasesNot yet recruitingNCT07811622Not applicable1 country
- SG301-SC Injection Safety Study in Subjects With Primary ITP PatientsRecruitingNCT07710248Phase 21 country
- OM336 in Autoimmune CytopeniasRecruitingNCT07083960Phase 12 countries
- Selective Mediterranean Diet in Immune ThrombocytopeniaNot yet recruitingNCT07798050Not applicable
- Multi-target Drugs Sequential Combination Therapy in Adults Patients With Newly Diagnosed Primary Immune ThrombocytopeniaRecruitingNCT07788456Phase 41 country
- A Phase Ib/II Clinical Trial of Multiple Doses of STSA-1301 Subcutaneous Injection in Healthy Subjects and Patients With Immune Thrombocytopenia (ITP)RecruitingNCT06929299Phase 1/21 country
- A Phase 1b/2a Study of Velinotamig in Adults With Relapsed/Refractory ITP and wAIHANot yet recruitingNCT07738822Phase 1/21 country
- Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)RecruitingNCT06371417Phase 120 countries
- Modeling the Early Stages of Autoimmunity Through the Study of Immunological Thrombocytopenic Purpura and Juvenile LupusNot yet recruitingNCT07680010Not applicable1 country
- Phase 1b Long-term Extension Trial of RAY121 in Immunological Diseases (RAINBOW-LTE Trial)Enrolling by invitationNCT06723106Phase 119 countries
- Eltrombopag Plus Telitacicept vs. Eltrombopag Alone for Steroid-refractory/Relapsed ITPNot yet recruitingNCT07687134Phase 21 country
- rhTPO Dose Escalation vs Eltrombopag Switch in ITPNot yet recruitingNCT07476846Not applicable
- A Study of Ianalumab in Addition to Eltrombopag in Pediatric Patients With Primary ITP Who Failed Corticosteroids.Not yet recruitingNCT07660172Phase 2
- TPO-RA Plus Baricitinib vs. TPO-RA for ITPNot yet recruitingNCT07669675Phase 2
- Atorvastatin Combined With NAC Plus Romiplostim for Management of ITPNot yet recruitingNCT07662525Not applicable1 country
- Sirolimus in Patients With Systemic Lupus Erythematosus-Associated Immune ThrombocytopeniaRecruitingNCT07657793Phase 2/31 country
- RN1201 Injection in the Treatment of Antibody-Mediated DiseasesRecruitingNCT07072247Phase 11 country
- A Clinical Study to Evaluate JCXH-213 in the Treatment of Adults With Primary Immune ThrombocytopeniaNot yet recruitingNCT07622329Phase 1
- Contribution of Anti-platelet Antibodies Identified With MAIPA Assay in the Demonstration of the Auto-immune Character of a Thrombocytopenia at DiagnosisRecruitingNCT04800458Not applicable1 country
- IASO-782 in Autoimmune Hematological DiseasesRecruitingNCT06534021Phase 11 country
- Phase I Study of SHR-2173 Injection in Patients With Primary Immune ThrombocytopeniaRecruitingNCT07206758Phase 11 country
- Romiplostim for Oral TPO-RA Resistant ITPRecruitingNCT07612319Not applicable1 country
- Safety and Efficacy of GL-2045 in Patients With Immune ThrombocytopeniaRecruitingNCT07605845Phase 11 country
- CD20 Monoclonal Antibody Combined With BTK Inhibitor for the Treatment of Refractory Immune-related CytopeniaNot yet recruitingNCT07574073Phase 1
- Universal STAR-T Cell Injection in R/R Autoimmune Diseases.Not yet recruitingNCT07599280Phase 11 country
- ATRA for Management of Primary ITPNot yet recruitingNCT07597395Phase 31 country
- A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune ThrombocytopeniaRecruitingNCT06544499Phase 317 countries
- High-Dose Dexamethasone Combined With Orelabrutinib Versus High-Dose Dexamethasone Combined With Placebo in Adult Patients With Newly Diagnosed Primary Immune ThrombocytopeniaRecruitingNCT07559331Phase 31 country
- Eltrombopag Combining Rituximab Versus Eltrombopag in the Management of Primary Immune Thrombocytopenia (ITP) in AdultsRecruitingNCT04518475Phase 41 country