Drug
Doxorubicin clinical trials
Also written Adriamycin, Rubex, hydroxydaunorubicin and FI 106.
Includes 237 studies of Liposomal doxorubicin.
Keep track of what changes. Save the Doxorubicin studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Other names
Studies by the year they started
831 studies that test it; most in 2008 (51)
| Year | Studies |
|---|---|
| 1990 | 1 |
| 1992 | 4 |
| 1993 | 2 |
| 1994 | 7 |
| 1995 | 7 |
| 1996 | 9 |
| 1997 | 15 |
| 1998 | 20 |
| 1999 | 19 |
| 2000 | 22 |
| 2001 | 20 |
| 2002 | 25 |
| 2003 | 34 |
| 2004 | 43 |
| 2005 | 36 |
| 2006 | 49 |
| 2007 | 41 |
| 2008 | 51 |
| 2009 | 42 |
| 2010 | 30 |
| 2011 | 21 |
| 2012 | 28 |
| 2013 | 27 |
| 2014 | 19 |
| 2015 | 27 |
| 2016 | 31 |
| 2017 | 23 |
| 2018 | 21 |
| 2019 | 36 |
| 2020 | 14 |
| 2021 | 16 |
| 2022 | 25 |
| 2023 | 18 |
| 2024 | 15 |
| 2025 | 18 |
| 2026 | 15 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 141 · Other 701
National Cancer Institute (NCI) (49) · M.D. Anderson Cancer Center (38) · Children's Oncology Group (28) · Memorial Sloan Kettering Cancer Center (20) · St. Jude Children's Research Hospital (14) · University of Washington (13) · Gynecologic Oncology Group (12) · European Organisation for Research and Treatment of Cancer - EORTC (11)
Often tested with
Tested in the same studies.
Cyclophosphamide (279) · Vincristine (158) · Prednisone (106) · Etoposide (99) · Paclitaxel (93) · Cisplatin (81) · Dexamethasone (74) · Ifosfamide (69)
Studies
Open first, then newest update. How each study uses Doxorubicin is read from its arms, and is right about nine times in ten.
Testing it · 842
- Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract CancerRecruitingPhase 2/3National Cancer Institute (NCI)NCT04628767Written as Doxorubicin Hydrochloride
- Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell LymphomaRecruitingPhase 2National Cancer Institute (NCI)NCT04002947Written as CHOP
- Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS)RecruitingPhase 2National Cancer Institute (NCI)NCT01419561Written as Liposomal Doxorubicin
- Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast CancerRecruitingPhase 3National Cancer Institute (NCI)NCT06058377Written as Doxorubicin
- Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced SarcomaRecruitingPhase 1National Cancer Institute (NCI)NCT05711615Written as Pegylated Liposomal Doxorubicin Hydrochloride
- Sequential Neoadjuvant Chemotherapy in Soft Tissue SarcomaRecruitingPhase 2Oslo University HospitalNCT04776525Written as Doxorubicin
- Epcoritamab With Dose Adjusted Etoposide, Cyclophosphamide, Vincristine, Doxorubicin, Prednisone and Rituximab (EPOCH-R) for the Treatment of Aggressive B-Cell Non-Hodgkin LymphomaRecruitingPhase 2University of WashingtonNCT07097363Written as Doxorubicin
- Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal HistologiesRecruitingPhase 1National Cancer Institute (NCI)NCT04847063Written as Doxorubicin
- A Study of PET Adapted Therapy and Non-invasive Monitoring for Previously Untreated Limited Stage Diffuse Large B Cell LymphomaRecruitingPhase 2University of RochesterNCT03758989Written as Doxorubicin
- Phase II Decentralized Pragmatic Trial of Adjuvant Doxorubicin - Trabectedin Chemotherapy in uLMSRecruitingPhase 2M.D. Anderson Cancer CenterNCT07076186Written as Doxorubicin Hydrochloride
- US/PA/E Imaging for Early Identification of Tumor Response in Patients With Stage II-III Triple Negative Breast Cancer Receiving Neoadjuvant Immunotherapy and ChemotherapyNot yet recruitingPhase 2Emory UniversityNCT07862751Written as Doxorubicin
- Interest of Post-operative Chemotherapy in Patients With Localised Uterine Leiomyosarcoma Suspected of Having a High Risk of Recurrence Based on a Biological Test Performed on the TumourRecruitingPhase 2UNICANCERNCT06524583Written as Doxorubicin
- Metastatic Ewing's Trial Testing Schedule Enhancement to Improve OutcomesRecruitingPhase 1H. Lee Moffitt Cancer Center and Research InstituteNCT07194044Written as Doxorubicin
- Pembrolizumab and Radiation Therapy With or Without Neoadjuvant Doxorubicin and Ifosfamide for the Treatment of High-Risk Resectable Undifferentiated Pleomorphic Sarcoma or Liposarcoma of the Extremity or Trunk WallNot yet recruitingPhase 3Ohio State University Comprehensive Cancer CenterNCT07823491Written as Doxorubicin
- Personalized Reduction of Chemotherapy Intensity Through ctDNA Evaluation for the Treatment of Patients With Advanced Hodgkin LymphomaRecruitingPhase 2University of WashingtonNCT06745076Written as Doxorubicin
- N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With NeuroblastomaRecruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT06528496Written as Doxorubicin
- PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric CancerRecruitingPhase 1City of Hope Medical CenterNCT04329494Written as Doxorubicin
- A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)RecruitingPhase 3Children's Oncology GroupNCT06401330Written as Doxorubicin
- A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWTRecruitingPhase 2Children's Oncology GroupNCT04322318Written as Doxorubicin
- Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLyRecruitingPhase 3Children's Oncology GroupNCT03959085Written as Doxorubicin Hydrochloride
See all 842 studies that test Doxorubicin →
Given in every arm · 628 — Doxorubicin is usual care beside what is tested
- A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)RecruitingPhase 2National Cancer Institute (NCI)NCT06124157Written as Doxorubicin
- Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk NeuroblastomaRecruitingPhase 3National Cancer Institute (NCI)NCT06172296Written as Doxorubicin
- A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and NivolumabRecruitingPhase 3National Cancer Institute (NCI)NCT05675410Written as Doxorubicin Hydrochloride
- Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated SarcomasRecruitingPhase 3National Cancer Institute (NCI)NCT06422806Written as Doxorubicin
- A Clinical Trial of MK-1045 and Rituximab in People With Follicular Lymphoma (MK-1045-007)RecruitingPhase 2/3Merck Sharp & Dohme LLCNCT07634471Written as Doxorubicin Hydrochloride
- Phase II Study of Second- Line Pembrolizumab Plus GVD for Relapsed or Refractory Hodgkin LymphomaRecruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT03618550Written as liposomal doxorubicin
- Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged LeukemiaRecruitingPhase 2National Cancer Institute (NCI)NCT06317662Written as Doxorubicin
- Durvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, DURVA+ TrialRecruitingPhase 2National Cancer Institute (NCI)NCT03907475Written as Pegylated Liposomal Doxorubicin Hydrochloride
- A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)RecruitingPhase 3Merck Sharp & Dohme LLCNCT06717347Written as Doxorubicin
- ctDNA-Guided Therapy for Relapsed/Refractory Hodgkin LymphomaRecruitingPhase 2Michael Spinner, MDNCT07021989Written as Liposomal Doxorubicin
- Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic LeukemiaRecruitingPhase 3Alliance for Clinical Trials in OncologyNCT03150693Written as Doxorubicin
- Epcoritamab in Combination With Dose Adjusted EPOCH-R for High-risk Burkitt Lymphoma (BL), The BEDROCK StudyNot yet recruitingPhase 2AIDS Malignancy ConsortiumNCT07662928Written as Doxorubicin
- A Study With NKT3964 for Adults With Advanced/Metastatic Solid TumorsRecruitingPhase 1NiKang Therapeutics, Inc.NCT06586957Written as Doxorubicin
- Cardioprotection Effect of LinagliptinNot yet recruitingPhase 3Tanta UniversityNCT07852546Written as Doxorubicin
- Testing the Addition of an Anti-cancer Drug, Lenalidomide, to the Usual Combination Chemotherapy Treatment ("EPOCH") for Adult T-Cell Leukemia-Lymphoma (ATLL)RecruitingPhase 1National Cancer Institute (NCI)NCT04301076Written as Doxorubicin Hydrochloride
- Testing Blinatumomab With or Without Revumenib in Patients With B-cell Acute Lymphoblastic Leukemia With a Genetic Change Requiring More TreatmentNot yet recruitingPhase 2SWOG Cancer Research NetworkNCT07636564Written as Doxorubicin
- A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)RecruitingPhase 3Merck Sharp & Dohme LLCNCT06966700Written as Doxorubicin
- Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID TrialRecruitingPhase 3SWOG Cancer Research NetworkNCT07220187Written as Doxorubicin Hydrochloride
- Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic LymphomaRecruitingPhase 2M.D. Anderson Cancer CenterNCT00501826Written as Doxorubicin Hydrochloride
- A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)RecruitingPhase 2Merck Sharp & Dohme LLCNCT06890884Written as Doxorubicin
Showing 20 of 628.
As the comparator · 121 — what is tested is compared with Doxorubicin
- A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube CancerRecruitingPhase 2/3Daiichi SankyoNCT06161025Written as PLD
- A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)RecruitingPhase 3Merck Sharp & Dohme LLCNCT07060807Written as Pegylated liposomal doxorubicin
- A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003).RecruitingPhase 1/2Merck Sharp & Dohme LLCNCT06843447Written as Pegylated liposomal doxorubicin
- Sacituzumab Govitecan With Bevacizumab Compared to Usual Chemotherapy (Carboplatin, Pegylated Liposomal Doxorubicin and Bevacizumab) for Treating Recurrent Platinum-Sensitive Ovarian Cancer After PARP Inhibitor Maintenance TherapyRecruitingPhase 2National Cancer Institute (NCI)NCT07504588Written as Pegylated Liposomal Doxorubicin Hydrochloride
- A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine CancerRecruitingPhase 3BioNTech SENCT06340568Written as Doxorubicin
- A Clinical Trial of Raludotatug Deruxtecan (R-DXd) With or Without Bevacizumab in Participants With Ovarian Cancer Who Have Progressed During Treatment With PARP-inhibitors Treatment on First Line Maintenance (MK-5909-008/ENGOT-ov107/GOG-3142 / REJOICE-Ovarian05)RecruitingPhase 3Merck Sharp & Dohme LLCNCT07743164Written as Pegylated liposomal doxorubicin (PLD)
- A Study to Investigate Mocertatug Rezetecan Compared With Standard of Care in Participants With Platinum-resistant Ovarian Cancer (BEHOLD-Ovarian01)RecruitingPhase 3GlaxoSmithKlineNCT07286266Written as Pegylated liposomal doxorubicin (PLD)
- A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)RecruitingPhase 3Merck Sharp & Dohme LLCNCT06312176Written as Liposomal doxorubicin
- A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian CancerRecruitingPhase 3Eli Lilly and CompanyNCT07213804Written as Pegylated liposomal doxorubicin (PLD)
- A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian CancerRecruitingPhase 3Verastem, Inc.NCT06072781Written as Pegylated liposomal doxorubicin
- Study to Assess the Efficacy and Safety of Rina-S With or Without Bevacizumab Compared to Investigator's Choice of Platinum-based Chemotherapy With or Without Bevacizumab as Second-line Treatment in Participants With Recurrent Platinum-sensitive Ovarian CancerRecruitingPhase 3GenmabNCT07564141Written as PLD
- A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular LymphomaRecruitingPhase 3Regeneron PharmaceuticalsNCT06091254Written as Doxorubicin
- An Extension Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer in ChinaRecruitingPhase 3GenmabNCT07604766Written as Pegylated liposomal doxorubicin (PLD)
- A Study to Investigate Mocertatug Rezetecan Compared With Chemotherapy in Participants With Endometrial Cancer After Platinum-based Chemotherapy and Immunotherapy (BEHOLD-Endometrial01)RecruitingPhase 3GlaxoSmithKlineNCT07286331Written as Doxorubicin
- A Study to Investigate Mocertatug Rezetecan With Bevacizumab Compared With Platinum Doublet With Bevacizumab in Participants With Platinum-sensitive Ovarian Cancer (BEHOLD-Ovarian02)RecruitingPhase 3GlaxoSmithKlineNCT07684612Written as Pegylated liposomal doxorubicin (PLD)
- Trastuzumab Rezetecan and Carboplatin ± Bevacizumab Versus Investigator's Choice Chemotherapy in Patients With Platinum-sensitive Recurrent Ovarian CancerNot yet recruitingPhase 2Sun Yat-sen UniversityNCT07776171Written as Carboplatin + pegylated liposomal doxorubicin
- Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)RecruitingPhase 3AstraZenecaNCT07044336Written as Doxorubicin
- A Multicenter, Prospective, Open-Label, Randomized Controlled Clinical Study of Orelabrutinib Combined With Obinutuzumab and Lenalidomide Versus Obinutuzumab Plus Chemotherapy for Treatment-Naive Follicular LymphomaNot yet recruitingPhase 3Ruijin HospitalNCT07719855Written as Doxorubicin
- AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian CancerRecruitingPhase 3AstraZenecaNCT07218809Written as Pegylated liposomal Doxorubicin (PLD)
- A Study Comparing BL-M07D1 With Physician's Choice of Chemotherapy in Patients With HER2-Expressing Platinum-Resistant Recurrent Epithelial Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal CancerNot yet recruitingPhase 3Sichuan Baili Pharmaceutical Co., Ltd.NCT07545460Written as Liposomal Doxorubicin
Showing 20 of 121.
Codes
What other systems call Doxorubicin · ClinicalTrials.gg INT007399
- MeSH (NLM) D004317DoxorubicinConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 80168379AGDOXORUBICINConfirmed FDA, NLM, Wikidata
- RxNorm 3639Confirmed FDA, Wikidata
- Wikidata Q18936doxorubicinConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C456DoxorubicinOne source FDA
- DrugBank DB00997One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D004317 | Doxorubicin | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 80168379AG | DOXORUBICIN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 3639 | — | Confirmed FDA, Wikidata |
| Wikidata | Q18936 | doxorubicin | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C456 | Doxorubicin | One source FDA |
| DrugBank | DB00997 | — | One source Wikidata |
Also registered as doxorubicin citrate (UNII AJQ2ZNG2WL) and doxorubicin hydrochloride (UNII 82F2G7BL4E · RxNorm 142433).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.