Lymphoma, B-Cell clinical trials
The registry lists 885 studies for Lymphoma, B-Cell across more than 10 countries. 286 are recruiting or about to start. 539 of them are mainly about Lymphoma, B-Cell (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 5 narrower conditions too, such as Lymphoma, Large B-Cell, Diffuse: 3,245 studies, 786 open.
ClinicalTrials.gov finds 4,727 studies for Lymphoma, B-Cell. How that becomes 885 here
This page counts the studies the registry files under Lymphoma, B-Cell, and those it files under no condition that list Lymphoma, B-Cellthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 4,727Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −2,350Filed under a narrower condition, counted on its own pageLymphoma, Large B-Cell, Diffuse 1,673 · Burkitt Lymphoma 361 · Lymphoma, B-Cell, Marginal Zone 260 · Lymphoma, AIDS-Related 20 · Lymphomatoid Granulomatosis 2
- −146List Lymphoma, B-Cell as a condition, but the registry did not file them under itMost often written as “DLBCL - Diffuse Large B Cell Lymphoma” (36), “Large B-cell Lymphoma” (14), and “Non-hodgkin Lymphoma,B Cell” (8). The registry filed them under other conditions only, most often Dendritic Cell Sarcoma, Interdigitating (43) and Recurrence (35).
- −1,346Match it another way182 name it in the title, 19 in a keyword, and 1,145 by a synonym or other text the search reads.
- 885The count on this page105 of them list Lymphoma, B-Cell in their own words; the registry filed them under no condition.
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· Enrollment: 300 → 450 participants
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Status
Who runs them
National Cancer Institute (NCI) (27) · M.D. Anderson Cancer Center (26) · Ruijin Hospital (18) · AstraZeneca (12) · Fred Hutchinson Cancer Center (11) · Institute of Hematology & Blood Diseases Hospital, China (10) · The Lymphoma Academic Research Organisation (10) · Mayo Clinic (9)
What is being tested here
Drugs under test in Lymphoma, B-Cell studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Alkylating agents 10 open · Tyrosine kinase inhibitors (TKIs) 7 open · Antimetabolites 6 open · Immune checkpoint inhibitors 4 open · Antibody-drug conjugates (ADCs) 4 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Feb 2027A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312) · Phase 3 · Acerta Pharma BV
- May 2027Modified DHAP Versus Standard DHAP in Relapsed/Refractory Diffused Large B-cell Lymphoma. · Phase 3 · King Edward Medical University
- Jun 2027Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma · Phase 3 · National Cancer Institute (NCI)
- Oct 2027A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) · Phase 3 · Loxo Oncology, Inc.
- Oct 2027An Open-Label Study Comparing Glofitamab and Polatuzumab Vedotin + Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone Versus Pola-R-CHP in Previously Untreated Patients With Large B-Cell Lymphoma · Phase 3 · Hoffmann-La Roche
- Nov 2027Study of BTK Inhibitor LOXO-305 Versus Approved BTK Inhibitor Drugs in Patients With Mantle Cell Lymphoma (MCL) · Phase 3 · Loxo Oncology, Inc.
- Nov 2026MB-CART19.1 r/r CD19+ B-cell Malignancies (BCM) · Miltenyi Biomedicine GmbH
- Nov 2026Metabolically Fit CD19 CAR T-cell Therapy With CD34 Selection in Patients With CD19+ Relapsed/Refractory NHL, CLL/SLL · Medical University of South Carolina
- Nov 2026The Safety and Efficacy of BRL-201 in the Treatment of r/r B Lymphocyte Non-Hodgkin Lymphoma · Bioray Laboratories
- Nov 2026Study Evaluating ISM8207 in Participants With Advanced Solid Tumors and Relapsed/Refractory B-Cell Lymphoma · InSilico Medicine Hong Kong Limited
Who these studies take
Of the 209 Lymphoma, B-Cell studies recruiting now, 129 (62%) set no upper age limit and 60 (29%) stop at 75 or younger. 37 (18%) take children under 18. 1 (<1%) are for women only and 0 (0%) for men only; 3 (1%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 25 (12%) | 25 (12%) |
| 18 | 199 (95%) | 198 (95%) |
| 30 | 200 (96%) | 199 (95%) |
| 40 | 197 (94%) | 196 (94%) |
| 50 | 197 (94%) | 196 (94%) |
| 65 | 200 (96%) | 199 (95%) |
| 75 | 190 (91%) | 189 (90%) |
| 85 | 137 (66%) | 136 (65%) |
Across all 885 studies, recruiting or not: 30% stop at 75 or younger and 7% at 65; 15% take children; <1% are for women only and <1% for men only; 1% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Lymphoma, B-Cell studies take
Of 207 phase 1 interventional studies under Lymphoma, B-Cell, half reached primary completion within 51 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 51 mo37–78 · 207 studies | 47 mo37–81 · 90 studies | 54 mo37–75 · 117 studies |
| Phase 1/2 | 71 mo55–96 · 94 studies | — | 64 mo45–82 · 52 studies |
| Phase 2 | 55 mo34–77 · 122 studies | — | 61 mo37–81 · 96 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting3
- GLORY: Glofit-GemOx With Liso-Cel For LymphomaOct 22, 2026NCT07711483
- Phase I Study of FXS0683 in the Treatment of Blood TumorsOct 14, 2026NCT07616089
- Bendamustine Versus Fludarabine/Cyclophosphamide for Lymphodepletion in Chimeric Antigen Receptor T-cell Immunotherapy (CAR-T): a Randomized Trial.Oct 13, 2026NCT07593482
Results posted3
- Mosunetuzumab and Polatuzumab Vedotin for Untreated Follicular LymphomaOct 28, 2026NCT05410418
- Observational Study of People Living With HIV Treated With CD19-directed CAR T CellOct 28, 2026NCT05784415
- Adaptive Bridging RT in R/R B-cell Lymphoma (Pre-CAR T)Oct 15, 2026NCT06004167
Stopped2
- CD19/CD20 Dual-CAR-T in B-cell Lymphoma PatientsTerminatedOct 29, 2026NCT04260932
- A Study of CLN-978 in Patients With Relapsed or Refractory (R/R) B Cell Non-Hodgkin Lymphoma (B-NHL)TerminatedOct 22, 2026NCT05879744
Newly registered9
- Smart 3: A Multi-Center Phase 2 Trial Of Golcadomide, Glofitamab And Polatuzumab Vedotin (G2P) For Patients With Newly Diagnosed Large B-Cell LymphomaNov 5, 2026NCT07917832
- GN001 for Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma and B-Cell Acute Lymphoblastic LeukemiaNov 2, 2026NCT07910708
- A Study to Evaluate Surovatamig Combined With R-CHOP in Participants of 18 to < 80 Years of Age With Previously Untreated Large B-cell Lymphoma With IPI Score 2 to 5Nov 2, 2026NCT07911553
- Clinical Study of SYS6055 Injection in Participants With Relapsed/Refractory B-Cell Non-Hodgkin LymphomaOct 29, 2026NCT07905261
- Non-Interventional Study of Ranicabtagene Autoleucel Injection for Relapsed/Refractory B-cell Non-Hodgkin LymphomaOct 22, 2026NCT07888530
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- A Study to Evaluate Treatment Patterns and Investigate Adult Patients With B-cell LymphomaOct 20, 2026NCT07882576
- RPM Signals in Outpatient CAR T TherapyOct 20, 2026NCT07882732
- Bispecific Antibody-Based Holding/Bridging Therapy Before CAR-T in Aggressive B-Cell LymphomasOct 20, 2026NCT07883135
- Microbiome Intervention for CAR-T Optimization and Response (MICRO-CART)Oct 13, 2026NCT07871747
Studies
Recruiting first, then most recently updated. Showing 50 of 885. Browse all 885 → or search them.
- CAR20(NAP)-T Therapy for B Cell Lymphoma (CARMA-01 Study)RecruitingNCT06002659Phase 1/21 country
- A Phase 1/2 Study of UB-VV400 With Rapamycin in Relapsed/Refractory B-cell MalignanciesRecruitingNCT07735533Phase 1/21 country
- BAFFR-targeting CAR T Cells for Patients With Relapsed or Refractory B-NHLRecruitingNCT05370430Phase 11 country
- Smart 3: A Multi-Center Phase 2 Trial Of Golcadomide, Glofitamab And Polatuzumab Vedotin (G2P) For Patients With Newly Diagnosed Large B-Cell LymphomaNot yet recruitingNCT07917832Phase 21 country
- A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )RecruitingNCT07101328Phase 112 countries
- A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell TherapyRecruitingNCT07188558Phase 33 countries
- In VIVO CAR-T Therapy for Relapsed/Refractory Hematological MalignanciesRecruitingNCT07239323Phase 11 country
- A Study of Axicabtagene Ciloleucel and Glofitamab as Second-Line Therapy for Relapsed or Refractory Patients With Large B Cell LymphomaRecruitingNCT06213311Phase 21 country
- Study of NX-5948 in Combination With Other Agents in Adults With B-cell MalignanciesRecruitingNCT07520006Phase 1/21 country
- IKS03 in Patients With Advanced B Cell Non-Hodgkin LymphomasRecruitingNCT05365659Phase 15 countries
- Trial of ONC-PluReceptor NK Cells With Epcoritamab and Tafasitamab for Patients With Recurrent or Refractory B-cell Non-Hodgkin LymphomaRecruitingNCT07283679Phase 1/21 country
- A Study of ARC-02 in B-cell NHLRecruitingNCT07691606Phase 16 countries
- Multi-CAR-T Cells Targeting B Cell LymphomasNot yet recruitingNCT04429438Phase 1/21 country
- A Phase I/II Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Relapsed/Refractory B-cell Non-Hodgkin LymphomaRecruitingNCT07123454Phase 1/28 countries
- A Study to Evaluate Surovatamig Combined With R-CHOP in Participants of 18 to < 80 Years of Age With Previously Untreated Large B-cell Lymphoma With IPI Score 2 to 5Not yet recruitingNCT07911553Phase 3
- Family Study of Lymphoproliferative DisordersRecruitingNCT006264961 country
- GN001 for Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma and B-Cell Acute Lymphoblastic LeukemiaRecruitingNCT07910708Phase 11 country
- A Study to Evaluate MK-1045 (CN201) in Participants With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (MK-1045-001/CN201-101)RecruitingNCT06189391Phase 11 country
- Clinical Study of SYS6055 Injection in Participants With Relapsed/Refractory B-Cell Non-Hodgkin LymphomaNot yet recruitingNCT07905261Phase 1/2
- Phase Ib Clinical Study of KeynatinibRecruitingNCT04807881Phase 11 country
- A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)RecruitingNCT06742996Phase 317 countries
- Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a SolutionRecruitingNCT061318011 country
- A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell MalignanciesRecruitingNCT06564038Phase 1/213 countries
- Biological Analysis of MABs in NHL in a Translational Prospective Observational Study Within Italian Clinical PracticeNot yet recruitingNCT077677991 country
- Bendamustine Versus Fludarabine/Cyclophosphamide for Lymphodepletion in Chimeric Antigen Receptor T-cell Immunotherapy (CAR-T): a Randomized Trial.RecruitingNCT07593482Phase 21 country
- CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell MalignanciesRecruitingNCT05442515Phase 1/21 country
- GLORY: Glofit-GemOx With Liso-Cel For LymphomaRecruitingNCT07711483Phase 21 country
- Geriatric Assessment Guided Interventions to Accelerate Functional Recovery After CAR-T Therapy for Patients 60 Years and Older With B-cell Non-Hodgkin Lymphoma or Multiple Myeloma, GOCART StudyRecruitingNCT06052826Phase 21 country
- Microbiome Intervention for CAR-T Optimization and Response (MICRO-CART)Not yet recruitingNCT07871747Phase 11 country
- Non-Interventional Study of Ranicabtagene Autoleucel Injection for Relapsed/Refractory B-cell Non-Hodgkin LymphomaNot yet recruitingNCT07888530
- Epcoritamab With Dose Adjusted Etoposide, Cyclophosphamide, Vincristine, Doxorubicin, Prednisone and Rituximab (EPOCH-R) for the Treatment of Aggressive B-Cell Non-Hodgkin LymphomaRecruitingNCT07097363Phase 21 country
- RPM Signals in Outpatient CAR T TherapyNot yet recruitingNCT07882732
- A Study to Evaluate Treatment Patterns and Investigate Adult Patients With B-cell LymphomaNot yet recruitingNCT078825761 country
- Bispecific Antibody-Based Holding/Bridging Therapy Before CAR-T in Aggressive B-Cell LymphomasRecruitingNCT07883135Phase 21 country
- This is a Phase I/II Interventional, Open-label Treatment Study Designed to Evaluate the Safety and Efficacy of Anti CD 19/22 CAR- T Cells Immunotherapy for Adults With Relapsed or Refractory Acute Lymphoblastic Leukemia/Lymphoma.Enrolling by invitationNCT07162571Phase 1/21 country
- Pomalidomide After CAR T-cell Therapy for the Treatment of Relapsed or Refractory CD19+ B-cell Leukemia or LymphomaRecruitingNCT07532525Phase 11 country
- A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell MalignanciesRecruitingNCT06528301Phase 12 countries
- Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHLRecruitingNCT06526793Phase 216 countries
- Phase I Study of FXS0683 in the Treatment of Blood TumorsRecruitingNCT07616089Phase 11 country
- Comparing the Effectiveness of the Immunotherapy Agents Rituximab or Mosunetuzumab in Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma, NORM TrialRecruitingNCT05886036Phase 22 countries
- CLIC-2201 for the Treatment of Relapsed/Refractory B Cell MalignanciesRecruitingNCT06208735Phase 11 country
- Study of a Communication Training Intervention for Large B-Cell Lymphoma ProvidersRecruitingNCT05940272Not applicable1 country
- AZD0486 1L Therapy for Elderly or Unfit Participants With LBCLRecruitingNCT07215585Phase 312 countries
- A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL)RecruitingNCT06173518Phase 13 countries
- A Compassionate Use (CU) Program of OdronextamabAvailableNCT05619367
- CD79b-19 CAR T Cells in Non-Hodgkin LymphomaRecruitingNCT06026319Phase 11 country
- Long-Term Follow-up of Patients Treated With Miltenyi Cell and Gene TherapiesRecruitingNCT06508775Not applicable1 country
- Study of GI001 in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma and B-Cell Acute Lymphoblastic LeukemiaRecruitingNCT07862010Early Phase 11 country
- Fully Human Bispecific Anti-CD20, Anti-CD19 CAR T Cells for Patients With Relapsed and/or Refractory B Cell MalignanciesNot yet recruitingNCT07335328Phase 11 country
- T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)RecruitingNCT06343311Phase 1/21 country